LOCUS       NM_001399191            2617 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus NOC2-like nucleolar associated transcriptional
            repressor (Noc2l), transcript variant 1, mRNA.
ACCESSION   NM_001399191 XM_006239584
VERSION     NM_001399191.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2617)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 2617)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 2617)
  AUTHORS   Wu,L., Ma,C.A., Zhao,Y. and Jain,A.
  TITLE     Aurora B interacts with NIR-p53, leading to p53 phosphorylation in
            its DNA-binding domain and subsequent functional suppression
  JOURNAL   J Biol Chem 286 (3), 2236-2244 (2011)
   PUBMED   20959462
REFERENCE   4  (bases 1 to 2617)
  AUTHORS   Heyne,K., Willnecker,V., Schneider,J., Conrad,M., Raulf,N.,
            Schule,R. and Roemer,K.
  TITLE     NIR, an inhibitor of histone acetyltransferases, regulates
            transcription factor TAp63 and is controlled by the cell cycle
  JOURNAL   Nucleic Acids Res 38 (10), 3159-3171 (2010)
   PUBMED   20123734
REFERENCE   5  (bases 1 to 2617)
  AUTHORS   Hublitz,P., Kunowska,N., Mayer,U.P., Muller,J.M., Heyne,K., Yin,N.,
            Fritzsche,C., Poli,C., Miguet,L., Schupp,I.W., van Grunsven,L.A.,
            Potiers,N., van Dorsselaer,A., Metzger,E., Roemer,K. and Schule,R.
  TITLE     NIR is a novel INHAT repressor that modulates the transcriptional
            activity of p53
  JOURNAL   Genes Dev 19 (23), 2912-2924 (2005)
   PUBMED   16322561
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Jan 4, 2022 this sequence version replaced XM_006239584.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360181.1991306.1,
                                           SRR26360186.2622828.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-67                JAXUCZ010000005.1  172102369-172102435
            68-226              JAXUCZ010000005.1  172102550-172102708
            227-401             JAXUCZ010000005.1  172103718-172103892
            402-530             JAXUCZ010000005.1  172103975-172104103
            531-651             JAXUCZ010000005.1  172105491-172105611
            652-742             JAXUCZ010000005.1  172105698-172105788
            743-821             JAXUCZ010000005.1  172106739-172106817
            822-932             JAXUCZ010000005.1  172106932-172107042
            933-1046            JAXUCZ010000005.1  172107309-172107422
            1047-1235           JAXUCZ010000005.1  172108181-172108369
            1236-1375           JAXUCZ010000005.1  172108545-172108684
            1376-1487           JAXUCZ010000005.1  172109488-172109599
            1488-1601           JAXUCZ010000005.1  172110582-172110695
            1602-1703           JAXUCZ010000005.1  172111082-172111183
            1704-1847           JAXUCZ010000005.1  172112144-172112287
            1848-1961           JAXUCZ010000005.1  172112412-172112525
            1962-2097           JAXUCZ010000005.1  172112806-172112941
            2098-2187           JAXUCZ010000005.1  172113399-172113488
            2188-2617           JAXUCZ010000005.1  172113739-172114168
FEATURES             Location/Qualifiers
     source          1..2617
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2617
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /note="NOC2-like nucleolar associated transcriptional
                     repressor"
                     /db_xref="GeneID:313777"
                     /db_xref="RGD:1309387"
     exon            1..67
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..2288
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /note="isoform 1 is encoded by transcript variant 1;
                     nucleolar complex protein 2 homolog"
                     /codon_start=1
                     /product="nucleolar complex protein 2 homolog isoform 1"
                     /protein_id="NP_001386120.1"
                     /db_xref="GeneID:313777"
                     /db_xref="RGD:1309387"
                     /translation="MAVSRCPRRRLAELTVDEFLASGFESESESELEDIKEPAAKEKK
                     GQRAVANREQRGAHTSPSLHKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDS
                     DTSVEEEEQFHSLPDRLEETSETEEDGGGDSDTLPRGLQRKKNEPVPVTLAMVERWKQ
                     GAMHHLTPKLFHEVVQAFRAAVATTQGDQEAPETCRFQVTDSAVFNALVTFCIRDLCG
                     CLQKLLFAKTVKDSSRMLLPSSSPLWGKLRVDVKTYLSAVVQLVASLAEATVSAAVLQ
                     HISSLVPYYLTFPKQCRMLVKRMIVLWSTGEESLRVLAFLVLIKVCRHKKESFLGPIL
                     KQMYIMYVRNCKFTSPSTLPLISFMQRTLTELLALDPSVSYQHAFLYIRQLAVHLRNA
                     MTTGKKETYQSVYNWQYVHCLYLWCRVLSALGSSEVLQPLLYPLSQIIIGCIKLLPTA
                     RFYPLRMHCVRALTLLSQTVGTFIPVLPFILEIFQQVDFNKRPGRMSSKPINFSVILK
                     LSSTNLQEKAYRDGLLEQLYDLIMEYLHGQAHSIAFPELVLPTVLQLKSFLRECKVAN
                     YCRQVRQLLEKVQENAEHIRSLRQRVTFSVSDQLAVDAWEKKVREEGTPLTRYYSHWK
                     KLRDREIQLEISGKERLEDLNFPEIKRRKVEDRKDEDRKELKDLFELDSSEGEDSTDF
                     FERGVPGLLESHRGMKEGGQEEEHKEDSDSSSEDGDTDTGVDLSELWQLAQGPQDELE
                     DLQLSEED"
     exon            68..226
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            227..401
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            402..530
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            531..651
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            652..742
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            743..821
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            822..932
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1046
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1235
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1375
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            1376..1487
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            1488..1601
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            1602..1703
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            1704..1847
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            1848..1961
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            1962..2097
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            2098..2187
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
     exon            2188..2617
                     /gene="Noc2l"
                     /gene_synonym="RGD1309387"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attgtgggcc cggaagtgcg gcgcatgctg ctttgagcat catggctgtg tctcgctgtc
       61 cacggaggcg actggcggag ttaacagtcg acgagttctt ggcctcgggc tttgagtcgg
      121 aatccgagtc ggagctggag gacatcaagg agcctgcggc gaaggagaaa aaagggcaaa
      181 gagcagtcgc taaccgggag cagcggggag cgcacacctc acccagcctg cataaggggc
      241 gtgcttctga gcacaaagac cagctctctc ggctcaagga cagagaccct gagttctaca
      301 agttcctgca ggagaatgac cagagcctac tgaacttcag tgactcagac acctctgtgg
      361 aggaagaaga gcaattccac tccctgccag ataggctgga ggaaacaagt gaaacggagg
      421 aagatggagg aggggacagt gacacattgc ccagagggct gcagaggaag aagaatgagc
      481 ctgtacctgt gacccttgcc atggtggaga ggtggaagca gggcgccatg caccacctta
      541 ctcccaagct gtttcatgaa gttgtacagg cattccgggc agctgtagcc accacccaag
      601 gagaccagga agctcctgag acttgcaggt tccaggtcac agacagtgct gtgttcaatg
      661 ctctggttac cttctgcatt cgagacctct gtggttgcct tcagaagcta ctgtttgcaa
      721 agacagtaaa ggatagcagc cggatgctgc tgccctctag tagcccactg tgggggaagc
      781 ttcgtgtgga tgtgaagaca tatctgagtg cagttgtaca gctggtcgcc tctctggctg
      841 aagccacggt gtctgccgct gtcctgcagc atatcagcag cttggttcct tactacctga
      901 ctttccctaa gcagtgccga atgctggtca agaggatgat agttctgtgg agcacgggtg
      961 aagaatctct gcgggtcctg gccttcctgg tactcatcaa agtctgccgg cacaagaagg
     1021 aatcctttct tggtcccatc ctgaagcaaa tgtacatcat gtatgtgaga aactgcaagt
     1081 tcacctctcc cagtaccctc cccctcataa gcttcatgca gcggacactg acggaactgc
     1141 ttgccctgga ccccagcgtc tcctatcagc acgccttcct ctacatccga cagcttgcag
     1201 tccacctgcg taatgctatg accactggca agaaggagac ataccagtct gtgtacaact
     1261 ggcaatacgt gcactgcctg tacctgtggt gtcgagtcct gagtgccctt ggttccagcg
     1321 aggtcctgca acccttactc taccctctct cacagatcat cattggctgt atcaagttgt
     1381 tgcccactgc ccgcttttat ccgttacgca tgcattgtgt acgtgccctg acactgctgt
     1441 cccagaccgt cggtaccttc atccctgttc tgcccttcat tctcgagatt ttccaacagg
     1501 tggacttcaa taagcggcca ggccgcatga gctccaagcc catcaacttc tctgtgatct
     1561 tgaagctgtc cagcaccaac ctgcaggaga aggcataccg ggatggtctg ctggaacagc
     1621 tgtatgacct tattatggaa tacctgcacg gccaggccca cagcatcgct ttcccggagt
     1681 tggtgctgcc tactgttcta cagctgaaat cttttctccg ggagtgcaaa gtggctaact
     1741 actgccggca ggtgcgtcag ctgctggaga aagtgcaaga gaacgcagaa cacatccgaa
     1801 gccttcgaca gagagtgacc ttcagtgtgt ctgaccagct ggcagtggat gcttgggaga
     1861 agaaggtccg tgaagagggg acccctctca ccagatacta cagccactgg aagaagctga
     1921 gggaccgtga gatccagctg gagatcagtg gcaaagagcg gctagaagac ctgaacttcc
     1981 cagagatcaa aaggcggaaa gtagaagaca ggaaggatga agacaggaaa gaattaaaag
     2041 acctgtttga gttggacagt tctgagggag aggacagcac agacttcttt gagagaggag
     2101 ttcctgggct cctggaatct cacagaggaa tgaaagaagg aggtcaggag gaagaacata
     2161 aggaagatag tgacagcagt tcagaggatg gagacacaga cacaggggtg gatctgagtg
     2221 aactgtggca gctggctcag ggaccacagg atgagctaga ggatcttcag ctctcagaag
     2281 aggactgagg gcctcctgcc agctcctgga ggccttgagg acaacaactg ttttgcaaga
     2341 ggacaggaga cagtaaacag ggttttattg ttacagcaca acagaacaag tgttctaaga
     2401 gccattatga ccctgaaaga gaactatttc tgcagagcct tctgctgccc caagcaggag
     2461 gctgaccctg acctacagag ttgtcccagt tcagagtggg gagggtggct ccatggcctc
     2521 tccactttgt ctttggtttg tctgcagacc tctgcagtta tccctagaag gtgaatccat
     2581 tactttctta ttaagccata tgttttcctt ttaaaaa
//
