LOCUS       NM_001401447            2349 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus nitric oxide associated 1 (Noa1), transcript
            variant 1, mRNA.
ACCESSION   NM_001401447 XM_006250845
VERSION     NM_001401447.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2349)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   2  (bases 1 to 2349)
  AUTHORS   Kolanczyk,M., Pech,M., Zemojtel,T., Yamamoto,H., Mikula,I.,
            Calvaruso,M.A., van den Brand,M., Richter,R., Fischer,B., Ritz,A.,
            Kossler,N., Thurisch,B., Spoerle,R., Smeitink,J., Kornak,U.,
            Chan,D., Vingron,M., Martasek,P., Lightowlers,R.N., Nijtmans,L.,
            Schuelke,M., Nierhaus,K.H. and Mundlos,S.
  TITLE     NOA1 is an essential GTPase required for mitochondrial protein
            synthesis
  JOURNAL   Mol Biol Cell 22 (1), 1-11 (2011)
   PUBMED   21118999
REFERENCE   3  (bases 1 to 2349)
  AUTHORS   Tang,T., Zheng,B., Chen,S.H., Murphy,A.N., Kudlicka,K., Zhou,H. and
            Farquhar,M.G.
  TITLE     hNOA1 interacts with complex I and DAP3 and regulates mitochondrial
            respiration and apoptosis
  JOURNAL   J Biol Chem 284 (8), 5414-5424 (2009)
   PUBMED   19103604
REFERENCE   4  (bases 1 to 2349)
  AUTHORS   Parihar,A., Parihar,M.S., Chen,Z. and Ghafourifar,P.
  TITLE     mAtNOS1 induces apoptosis of human mammary adenocarcinoma cells
  JOURNAL   Life Sci 82 (21-22), 1077-1082 (2008)
   PUBMED   18456285
REFERENCE   5  (bases 1 to 2349)
  AUTHORS   Zemojtel,T., Kolanczyk,M., Kossler,N., Stricker,S., Lurz,R.,
            Mikula,I., Duchniewicz,M., Schuelke,M., Ghafourifar,P.,
            Martasek,P., Vingron,M. and Mundlos,S.
  TITLE     Mammalian mitochondrial nitric oxide synthase: characterization of
            a novel candidate
  JOURNAL   FEBS Lett 580 (2), 455-462 (2006)
   PUBMED   16380119
  REMARK    Erratum:[FEBS Lett. 2007 May 15;581(10):2072-3]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            On Feb 11, 2022 this sequence version replaced XM_006250845.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643296.32900.1,
                                           SRR26643290.44155.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1228              JAXUCZ010000014.1  31189570-31190797
            1229-1393           JAXUCZ010000014.1  31192007-31192171
            1394-1599           JAXUCZ010000014.1  31193171-31193376
            1600-1731           JAXUCZ010000014.1  31195036-31195167
            1732-1848           JAXUCZ010000014.1  31199014-31199130
            1849-1966           JAXUCZ010000014.1  31202543-31202660
            1967-2349           JAXUCZ010000014.1  31205218-31205600
FEATURES             Location/Qualifiers
     source          1..2349
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p11"
     gene            1..2349
                     /gene="Noa1"
                     /gene_synonym="RGD1359460"
                     /note="nitric oxide associated 1"
                     /db_xref="GeneID:289562"
                     /db_xref="RGD:1359460"
     exon            1..1228
                     /gene="Noa1"
                     /gene_synonym="RGD1359460"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..2163
                     /gene="Noa1"
                     /gene_synonym="RGD1359460"
                     /note="isoform 1 is encoded by transcript variant 1;
                     MMR_HSR1 domain containing protein RGD1359460; nitric
                     oxide-associated protein 1"
                     /codon_start=1
                     /product="nitric oxide-associated protein 1 isoform 1"
                     /protein_id="NP_001388376.1"
                     /db_xref="GeneID:289562"
                     /db_xref="RGD:1359460"
                     /translation="MLPARLGCRLLCGLLRGPAPAAACRGPARWLLEGKCEATICQRG
                     SSLGRRAPPSSTATEDCEEGTDTEERFLFPEYVPERTPEEQLRELRELRELQQLQQEK
                     ERQRLQRREERLQQKLRAGLRALPVPELPDASVPPSGIYCSGCGAELHCQHPGLPGYL
                     PGEKFRDAAQAEGGLARTVCQRCWLLVHHRRALRLQVSRDQYLELVSTALQRPGPALV
                     LYMVDLLDLPDALLPDLPKLVGPKQLFVLGNKVDLLPQDAPGYLQRLRKRLWNDCIRA
                     GLVVAPGHRGPQYPTGNEPLDEIKNQNPSSRSRTVVKDVRLISAKTGYGVEELISALQ
                     RSWRYRGDVYLVGTTNAGKSTLFNTLLESDYCTAKGSEAIDRATISPWPGTTLNLLKF
                     PICNPTPYRMFKRQKRLQEDASKTEEDLSEQEQSQLNQLKKHGYIVGRVGRTFLHSRQ
                     QKEEVPFEFDADSLAFDMGNEPVVSVRKSTKQTELTPEDVKDAHWFYDTPGITKENCI
                     LNLLTEKEIDIVLPTHSIIPRTFVLKPGMVLFLGGIARVDFLQGNQSAWFTVVASNFL
                     PVHISSLDKADALYEKHAGQELLLVPMGGKERMAQFPPLVAEDITLKGGGEAEAVADI
                     KFSSAGWVAVTPYSEGTLHLRAYTPEGTALTVHPPVLPYIVNVKGQRIKKSAAYKTKK
                     PPSLIHNLKKHR"
     exon            1229..1393
                     /gene="Noa1"
                     /gene_synonym="RGD1359460"
                     /inference="alignment:Splign:2.1.0"
     exon            1394..1599
                     /gene="Noa1"
                     /gene_synonym="RGD1359460"
                     /inference="alignment:Splign:2.1.0"
     exon            1600..1731
                     /gene="Noa1"
                     /gene_synonym="RGD1359460"
                     /inference="alignment:Splign:2.1.0"
     exon            1732..1848
                     /gene="Noa1"
                     /gene_synonym="RGD1359460"
                     /inference="alignment:Splign:2.1.0"
     exon            1849..1966
                     /gene="Noa1"
                     /gene_synonym="RGD1359460"
                     /inference="alignment:Splign:2.1.0"
     exon            1967..2349
                     /gene="Noa1"
                     /gene_synonym="RGD1359460"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcgttgtctg gtcctgggag tttctcggac gctaacacgc gtgcgcgctc gaggccccgc
       61 cctcctcgcg ctgtccacat gctgcccgcg cgcctgggtt gtaggctgct gtgcgggctc
      121 ctacggggcc ccgcaccagc cgctgcgtgc cgtggcccag cacggtggct cctggagggg
      181 aagtgtgagg ccaccatctg ccagcgtgga tcatccctgg gccgccgagc tccccctagt
      241 tccacggcga ccgaggactg tgaagaagga accgacacgg aggaacgctt tctgttcccg
      301 gagtacgtcc cggagcggac ccctgaggaa cagctgcggg aattgcggga gctgcgggag
      361 ttgcagcagc tgcagcagga gaaagaacga cagaggttgc agcggcggga ggagcggctt
      421 cagcagaaac tgcgggcagg cctccgggct ctgccggtcc cggagcttcc agacgcatcg
      481 gtgccgccca gcggcatcta ctgctcgggc tgcggagccg agctccactg ccagcatcct
      541 ggcctgcccg gctacttgcc gggcgagaag ttccgcgatg ctgcccaggc ggaaggtggc
      601 ctggcgcgga ccgtgtgcca acgctgctgg ctactggtgc accaccgccg tgccctgcgc
      661 ctgcaggtga gccgcgatca gtacctggag cttgtgagca ccgcgctgca gagaccgggg
      721 cccgctctgg tgctttatat ggtggatctg cttgacctgc cggacgctct gctgcccgac
      781 ttgcccaagc tggtgggccc caagcagctc ttcgtgctgg ggaataaagt ggacctgctg
      841 ccccaggatg cgcccggcta cttacagcgg ctgcggaagc ggctgtggaa cgactgtatc
      901 cgcgccgggc tcgtggtggc ccctggtcat cgaggaccac agtaccctac tggaaatgag
      961 ccactggacg agataaagaa tcagaatccg tcgtccaggt cccgcacggt ggtcaaagac
     1021 gtgcggctga ttagcgccaa gacgggctat ggagttgaag aactgatctc tgctcttcag
     1081 cgttcctggc gctaccgcgg cgatgtctac ctggtgggca ccacgaacgc tggcaagtcc
     1141 actctcttta acacactcct ggagtctgat tactgcaccg ccaagggctc cgaagccatc
     1201 gacagagcca ccatctcccc ctggccaggt accacattaa acctcctgaa gtttcctatt
     1261 tgcaacccga ctccttacag aatgttcaaa agacaaaaaa ggcttcaaga ggatgcgagc
     1321 aaaactgaag aagatcttag tgagcaagaa caaagtcagc tcaatcagct gaaaaagcac
     1381 ggctacatag taggaagagt cggaagaaca ttcttgcact ccagacagca gaaggaagag
     1441 gttccctttg agtttgatgc tgactcgctg gcctttgaca tgggaaatga acccgttgtg
     1501 tctgtgcgca aaagcaccaa acaaacagaa ctgaccccag aagacgtgaa agacgcccac
     1561 tggttttatg acacccctgg gatcacaaaa gaaaactgca ttctaaatct tctaacagaa
     1621 aaagaaatcg atattgtttt gccgacacat tctattatcc cgagaacctt tgtcctcaag
     1681 cccggaatgg ttctattttt gggtggtata gcccgagtag atttcctaca gggaaatcaa
     1741 tcagcctggt ttacagttgt ggcttccaac ttccttcccg ttcatatttc ttccttggac
     1801 aaggcagatg ctctatatga gaaacatgca ggtcaggagt tactgctggt tccaatggga
     1861 gggaaagaac gaatggccca gtttccccct cttgttgctg aagacattac gttaaaggga
     1921 ggtggagagg ccgaagcagt agctgatatc aagttctcct ctgcaggttg ggttgcagta
     1981 actccttatt ctgagggcac actgcatctc cgagcttaca cacctgaagg gactgctctg
     2041 actgtccacc cccctgtctt gccatatatc gttaatgtca aaggacagcg catcaagaaa
     2101 agtgcggcct ataaaaccaa gaagcctccg tccctcatac acaatctgaa gaagcacaga
     2161 tgagtgaggc agatgtgggc cacactggat ataaatgcag aagtatgtcg aagtatacta
     2221 aacgcaaaaa taataaagac actcgaacac ttatcattca cttttaaaga tcttcaaagt
     2281 caactgtttg aactacttga gactatgctt atgtaataca gtatttataa ataaaaacta
     2341 ttcttagta
//
