LOCUS       NM_001034148            1099 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus N-myc (and STAT) interactor (Nmi), mRNA.
ACCESSION   NM_001034148 XM_229916
VERSION     NM_001034148.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1099)
  AUTHORS   Brozzi,F., Gerlo,S., Grieco,F.A., Nardelli,T.R., Lievens,S.,
            Gysemans,C., Marselli,L., Marchetti,P., Mathieu,C., Tavernier,J.
            and Eizirik,D.L.
  TITLE     A combined 'omics' approach identifies N-Myc interactor as a novel
            cytokine-induced regulator of IRE1 protein and c-Jun N-terminal
            kinase in pancreatic beta cells
  JOURNAL   J Biol Chem 289 (30), 20677-20693 (2014)
   PUBMED   24936061
  REMARK    GeneRIF: identified NMI induction as a novel negative feedback
            mechanism that decreases IRE1alpha-dependent activation of JNK and
            apoptosis in cytokine-exposed beta cells
REFERENCE   2  (bases 1 to 1099)
  AUTHORS   Wang,J., Yang,B., Hu,Y., Zheng,Y., Zhou,H., Wang,Y., Ma,Y., Mao,K.,
            Yang,L., Lin,G., Ji,Y., Wu,X. and Sun,B.
  TITLE     Negative regulation of Nmi on virus-triggered type I IFN production
            by targeting IRF7
  JOURNAL   J Immunol 191 (6), 3393-3399 (2013)
   PUBMED   23956435
REFERENCE   3  (bases 1 to 1099)
  AUTHORS   Yu,H., Tardivo,L., Tam,S., Weiner,E., Gebreab,F., Fan,C.,
            Svrzikapa,N., Hirozane-Kishikawa,T., Rietman,E., Yang,X.,
            Sahalie,J., Salehi-Ashtiani,K., Hao,T., Cusick,M.E., Hill,D.E.,
            Roth,F.P., Braun,P. and Vidal,M.
  TITLE     Next-generation sequencing to generate interactome datasets
  JOURNAL   Nat Methods 8 (6), 478-480 (2011)
   PUBMED   21516116
REFERENCE   4  (bases 1 to 1099)
  AUTHORS   Bannasch,D., Weis,I. and Schwab,M.
  TITLE     Nmi protein interacts with regions that differ between MycN and Myc
            and is localized in the cytoplasm of neuroblastoma cells in
            contrast to nuclear MycN
  JOURNAL   Oncogene 18 (48), 6810-6817 (1999)
   PUBMED   10597290
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC100089.1.
            
            [WARNING] On Jul 19, 2024 this sequence was replaced by
            NM_001034148.2.
            
            On Oct 14, 2005 this sequence version replaced XM_229916.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100089.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1099
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q12"
     gene            1..1099
                     /gene="Nmi"
                     /note="N-myc (and STAT) interactor"
                     /db_xref="GeneID:311021"
                     /db_xref="RGD:1311721"
     exon            1..19
                     /gene="Nmi"
                     /inference="alignment:Splign:2.1.0"
     exon            20..95
                     /gene="Nmi"
                     /inference="alignment:Splign:2.1.0"
     exon            96..191
                     /gene="Nmi"
                     /inference="alignment:Splign:2.1.0"
     CDS             114..956
                     /gene="Nmi"
                     /codon_start=1
                     /product="N-myc-interactor"
                     /protein_id="NP_001029320.1"
                     /db_xref="GeneID:311021"
                     /db_xref="RGD:1311721"
                     /translation="MRENSKLDEEIKKLEAELQSNAREFQIKENVPERKLKFTSVERP
                     EDGDHFSNSSCSFQVNSQILYEVQRGQALITFEKEEVAQNVISMGTHVVQMEGTSVKV
                     SAHPVPLSTGVRFQVHVDISKMKINVTGIPDELSEEQTRDKLELSFYKSKNGGGEVES
                     VDYDRKSRSAVITFVVAGVADKILKKKTYPLYMNQKWYNVTVSPFIERRLEKYQVFSA
                     VSKKTVLLTGLDGIRVDEETGEDLLNIHFQRKNNGGGEVEVVKCSLDQSFIACFEEEA
                     RGTT"
     exon            192..354
                     /gene="Nmi"
                     /inference="alignment:Splign:2.1.0"
     exon            355..461
                     /gene="Nmi"
                     /inference="alignment:Splign:2.1.0"
     exon            462..648
                     /gene="Nmi"
                     /inference="alignment:Splign:2.1.0"
     exon            649..755
                     /gene="Nmi"
                     /inference="alignment:Splign:2.1.0"
     exon            756..1019
                     /gene="Nmi"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgctgcgcg gcagagaggg gcgtcatgga taacaacgta aggcaagctt atgaagagtg
       61 ctcaccagag aaggacatca tgagaggcga acaaaggatt acttcatgaa attatgaggg
      121 aaaacagcaa gctagacgag gagatcaaaa aacttgaagc tgaattgcag tcgaatgcca
      181 gagaattcca aattaaagag aatgtaccag aaagaaagct taaattcacc tctgtggaga
      241 gacccgagga tggagaccat ttctcaaata gctcctgttc atttcaagtg aactcgcaaa
      301 ttctttatga ggtacagaga ggacaagcgc ttatcacctt tgagaaggaa gaagttgcac
      361 agaacgtgat atcgatgggg acgcatgtcg tgcagatgga aggcacctcg gtgaaggtct
      421 ctgcacaccc agtcccactg agcacaggtg tcagatttca ggttcatgtg gacatttcta
      481 aaatgaagat caatgttacg gggattcccg atgaactgtc tgaggagcag acaagggaca
      541 agctggagct gagcttctat aagtccaaga atggcggcgg agaagtggaa agtgtagact
      601 atgacaggaa gtccagaagc gctgtcatca catttgtggt agctggagtt gctgacaaga
      661 ttttgaaaaa gaaaacctat cctctctaca tgaatcagaa gtggtataac gtgactgttt
      721 ccccatttat agaaagacgc ttggaaaagt accaggtgtt ttcagctgtg tccaagaaga
      781 cagtacttct gactggatta gacggcattc gtgtagatga ggagactggg gaagacttac
      841 tcaacatcca cttccaacgg aagaataacg gagggggaga agtggaggtg gtcaagtgtt
      901 ctctagatca gtccttcata gcatgtttcg aagaagaggc cagaggaacc acatgaaact
      961 tacagctctg agcccaaatc attgtcaaca tttatgaaat attgttttcc ttaacaataa
     1021 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1081 aaaaaaaaaa aaaaaaaaa
//
