LOCUS       NM_138532               1659 bp    mRNA    linear   ROD 14-APR-2024
DEFINITION  Rattus norvegicus NME/NM23 family member 7 (Nme7), mRNA.
ACCESSION   NM_138532
VERSION     NM_138532.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1659)
  AUTHORS   Sedova,L., Prochazka,J., Zudova,D., Bendlova,B., Vcelak,J.,
            Sedlacek,R. and Seda,O.
  TITLE     Heterozygous Nme7 Mutation Affects Glucose Tolerance in Male Rats
  JOURNAL   Genes (Basel) 12 (7), 1087 (2021)
   PUBMED   34356103
  REMARK    GeneRIF: Heterozygous Nme7 Mutation Affects Glucose Tolerance in
            Male Rats.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1659)
  AUTHORS   Sedova,L., Bukova,I., Bazantova,P., Petrezselyova,S., Prochazka,J.,
            Skolnikova,E., Zudova,D., Vcelak,J., Makovicky,P., Bendlova,B.,
            Seda,O. and Sedlacek,R.
  TITLE     Semi-Lethal Primary Ciliary Dyskinesia in Rats Lacking the Nme7
            Gene
  JOURNAL   Int J Mol Sci 22 (8), 3810 (2021)
   PUBMED   33916973
  REMARK    GeneRIF: Semi-Lethal Primary Ciliary Dyskinesia in Rats Lacking the
            Nme7 Gene.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1659)
  AUTHORS   Sedova,L., Skolnikova,E., Hodulova,M., Vcelak,J., Seda,O. and
            Bendlova,B.
  TITLE     Expression profiling of Nme7 interactome in experimental models of
            metabolic syndrome
  JOURNAL   Physiol Res 67 (Suppl 3), S543-S550 (2018)
   PUBMED   30484681
  REMARK    GeneRIF: ln a rat model of metabolic syndrome, expression of Nme7
            may have relevance for carbohydrate and lipid metabolism as well as
            ciliogenesis.
REFERENCE   4  (bases 1 to 1659)
  AUTHORS   Vogel,P., Read,R.W., Hansen,G.M., Payne,B.J., Small,D., Sands,A.T.
            and Zambrowicz,B.P.
  TITLE     Congenital hydrocephalus in genetically engineered mice
  JOURNAL   Vet Pathol 49 (1), 166-181 (2012)
   PUBMED   21746835
REFERENCE   5  (bases 1 to 1659)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   6  (bases 1 to 1659)
  AUTHORS   Lai,C.K., Gupta,N., Wen,X., Rangell,L., Chih,B., Peterson,A.S.,
            Bazan,J.F., Li,L. and Scales,S.J.
  TITLE     Functional characterization of putative cilia genes by high-content
            analysis
  JOURNAL   Mol Biol Cell 22 (7), 1104-1119 (2011)
   PUBMED   21289087
REFERENCE   7  (bases 1 to 1659)
  AUTHORS   Tarantino,C., Paolella,G., Cozzuto,L., Minopoli,G., Pastore,L.,
            Parisi,S. and Russo,T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   8  (bases 1 to 1659)
  AUTHORS   Vogel,P., Read,R., Hansen,G.M., Freay,L.C., Zambrowicz,B.P. and
            Sands,A.T.
  TITLE     Situs inversus in Dpcd/Poll-/-, Nme7-/-, and Pkd1l1-/- mice
  JOURNAL   Vet Pathol 47 (1), 120-131 (2010)
   PUBMED   20080492
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF202049.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF202049.1, BC060314.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132265
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1659
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q23"
     gene            1..1659
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /note="NME/NM23 family member 7"
                     /db_xref="GeneID:171566"
                     /db_xref="RGD:619880"
     exon            1..20
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
     exon            21..203
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
     exon            204..286
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
     CDS             227..1414
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /EC_number="2.7.4.6"
                     /note="nucleoside diphosphate kinase 7; NDK 7; NDP kinase
                     7; non-metastatic cells 7, protein expressed in
                     (nucleoside-diphosphate kinase); protein kinase NME7; NDP
                     kinase homolog 7; 3'-5' exonuclease NME7"
                     /codon_start=1
                     /product="nucleoside diphosphate kinase homolog 7"
                     /protein_id="NP_612541.1"
                     /db_xref="GeneID:171566"
                     /db_xref="RGD:619880"
                     /translation="MKAGQQGRSCGLISPYLAPKNQSERFAFIAEWYDPNASLLRRYE
                     LLYYPVDGSVEMHDVKNRRTFLKRTKYEDLRVEDLFIGNKVNVFSRQLVLIDYGDQYT
                     ARQLGSRKEKTLALIKPDAVSKAGEIIEMINKSGFTITKLRMMTLSRKEAADFHVDHH
                     SRPFYNELIQFITSGPVIAMEILRDDAICEWKRLLGPANSGIARSEAPGSVRALFGTD
                     GIRNAAHGSDTFESAAREMELFFPSSGGCGPTNTAKFTNCTCCIIKPHAISEGMLGKI
                     LIAIRDACFEISAIQMFNMDRANVEEFYEVYKGVLSDYNDMVTELYSGPCVAIEIQQS
                     NPTKTFREFCGPSDPEIARHLRPETLRANFGKTKVQNAVHCTDLPEDGLLEVQYFFKI
                     LDN"
     exon            287..394
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
     exon            395..561
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
     exon            562..672
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
     exon            673..723
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
     exon            724..931
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
     exon            932..1037
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1102
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
     exon            1103..1171
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1273
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
     exon            1274..1381
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
     exon            1382..1659
                     /gene="Nme7"
                     /gene_synonym="nm23-H7; Nm23-r7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctgagatcc acaaactatg ttttcaagct tgcaggccca tttcgacgtg atgctgtatc
       61 atcactaacc tgaatattgg agtgtgttct cccaggcggc ggagttctgc ctagcatctc
      121 ctaccaggac cgcttagtaa tagatgtctg caggctcagc ttctagtcca ttgcatactt
      181 tccagatctc tgtgttttag cagccggcat tgcatcctcg ggcagcatga aagctggtca
      241 gcagggaaga agttgcggtt tgatttctcc gtatcttgca cccaagaatc agagtgagag
      301 gtttgctttc attgcagagt ggtatgaccc aaatgcttca ctgctccgac gctatgagct
      361 tctgtactac ccggtagatg gatctgttga aatgcatgat gtcaagaatc gtcgcacctt
      421 cttaaagcgg accaagtatg aggacctgcg cgtggaagat ttatttatag gcaacaaagt
      481 caatgtgttt tctcgacagc tggtgctgat tgactatggg gaccagtaca cagcccgcca
      541 gctgggcagc aggaaagaga aaactttagc cctcatcaaa ccggatgcag tatcgaaggc
      601 tggagaaatc attgagatga taaacaaaag tgggttcact ataaccaaac tccgaatgat
      661 gacgctgtca aggaaagaag cagcagactt tcatgtagac caccactcaa ggccttttta
      721 taacgaactg atccagttta tcacaagtgg gcctgttatt gccatggaga tcttgagaga
      781 tgatgccata tgtgagtgga aaaggttgct tggacccgca aactctggga tagcgcgttc
      841 agaagccccc ggaagcgtcc gagccctctt tgggacagat ggcataagaa atgcggctca
      901 cggctctgat acttttgagt ccgctgccag agaaatggaa ttatttttcc cctccagtgg
      961 aggctgtggc ccaacaaaca ctgctaaatt taccaattgt acctgctgca ttatcaagcc
     1021 ccatgctatc agtgaaggaa tgttgggaaa gattttaata gctattcgag atgcatgctt
     1081 tgagatctca gcaatacaga tgttcaatat ggatcgagct aatgttgaag aattctatga
     1141 agtctataaa ggtgtactgt ccgattataa tgacatggtg acagagctgt actccggccc
     1201 ttgcgtagca atagagatcc agcagagcaa tcctacgaag acgttccgag aattctgtgg
     1261 accttccgat cctgaaatcg ccaggcattt acgacctgag accctcaggg caaattttgg
     1321 taaaaccaag gttcaaaatg ctgttcattg tacagatctg ccagaggatg ggctcctgga
     1381 ggtccagtat ttcttcaaga tcttggataa ttagccgtac agagtaaaga caacacagac
     1441 ggagacgctc agacaagtga gtcacacacg tgaagaatgt gttcattctt ttattgtcca
     1501 ttgtgttaac ctgactgaca caagaccaac aagagcactg tactcctggc aatcattaca
     1561 tatgctagaa catggatttg cactgtagac aacatttaac accagtctat ggggtactgc
     1621 attgcttttt ataaagttca aaataaagat tttattttc
//
