LOCUS       NM_001107682            1848 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus NMD3 ribosome export adaptor (Nmd3), mRNA.
ACCESSION   NM_001107682 XM_001067083
VERSION     NM_001107682.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1848)
  AUTHORS   Bai B, Moore HM and Laiho M.
  TITLE     CRM1 and its ribosome export adaptor NMD3 localize to the nucleolus
            and affect rRNA synthesis
  JOURNAL   Nucleus 4 (4), 315-325 (2013)
   PUBMED   23782956
REFERENCE   2  (bases 1 to 1848)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 1848)
  AUTHORS   Panse VG and Johnson AW.
  TITLE     Maturation of eukaryotic ribosomes: acquisition of functionality
  JOURNAL   Trends Biochem Sci 35 (5), 260-266 (2010)
   PUBMED   20137954
  REMARK    Review article
REFERENCE   4  (bases 1 to 1848)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 1848)
  AUTHORS   Zemp I and Kutay U.
  TITLE     Nuclear export and cytoplasmic maturation of ribosomal subunits
  JOURNAL   FEBS Lett 581 (15), 2783-2793 (2007)
   PUBMED   17509569
  REMARK    Review article
REFERENCE   6  (bases 1 to 1848)
  AUTHORS   Thomas F and Kutay U.
  TITLE     Biogenesis and nuclear export of ribosomal subunits in higher
            eukaryotes depend on the CRM1 export pathway
  JOURNAL   J Cell Sci 116 (Pt 12), 2409-2419 (2003)
   PUBMED   12724356
REFERENCE   7  (bases 1 to 1848)
  AUTHORS   Trotta CR, Lund E, Kahan L, Johnson AW and Dahlberg JE.
  TITLE     Coordinated nuclear export of 60S ribosomal subunits and NMD3 in
            vertebrates
  JOURNAL   EMBO J 22 (11), 2841-2851 (2003)
   PUBMED   12773398
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC161998.1.
            
            On Sep 1, 2012 this sequence version replaced NM_001107682.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161998.1, SRR8487231.172970.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132274, SAMD00132286
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1848              BC161998.1         1-1848
FEATURES             Location/Qualifiers
     source          1..1848
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q32"
     gene            1..1848
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /note="NMD3 ribosome export adaptor"
                     /db_xref="GeneID:310512"
                     /db_xref="RGD:1308468"
     exon            1..131
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            132..185
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..1653
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /note="NMD3 homolog"
                     /codon_start=1
                     /product="60S ribosomal export protein NMD3"
                     /protein_id="NP_001101152.1"
                     /db_xref="GeneID:310512"
                     /db_xref="RGD:1308468"
                     /translation="MEYMTESVDRSPGHILCCECGVPISPNPANICVACLRSKVDISQ
                     GVPKQVSISFCKQCQRYFQPPASWVQCALESRELLALCLKKIKAPLSKVRLVDAGFVW
                     TEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVR
                     QKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQGTVPC
                     RYKSSQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICICIR
                     VTSAIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVIECSIVRDLKRNAGAG
                     VISKKHTLGEVWIQKTSEMDTDKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEHVNK
                     MKSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARDREDMDTDDERQYQDFLEDLEEDE
                     TIRKNVNIYRDSTVPVESDTDDEGAPRISLAEMLEDLRISQDATGEEGASMMS"
     exon            186..320
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            321..417
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            418..498
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            499..627
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            628..718
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            719..797
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            798..894
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            895..1012
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1158
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1271
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            1272..1344
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1451
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1522
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..1848
                     /gene="Nmd3"
                     /gene_synonym="RGD1308468"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acacccttca acacgcggga tttccggtct tcctatcgcg agatctccct ggtggtggtg
       61 tggcgctgtg ggaactgaag gtgcgtcccg gccagcaggt tgccggctgt tcgtgtcttt
      121 tgccctgtca cgccccgaac catggagtac atgacagaat ctgttgaccg cagcccggga
      181 cacatcttgt gctgtgaatg tggtgtccca attagtccaa atcctgccaa tatttgtgtg
      241 gcctgtttac gaagtaaagt tgacatcagc caaggtgttc caaagcaggt ctccatttct
      301 ttctgcaaac aatgtcaaag atattttcag ccaccagcat catgggtaca gtgtgcttta
      361 gaatccaggg aacttcttgc tttgtgtttg aaaaaaatta aagctcctct gagtaaggtt
      421 cggcttgttg acgcaggctt tgtttggact gagcctcatt ccaagagact taaagttaaa
      481 ttgacaattc agaaagaggt gatgaatggt gctatcctgc agcaagtgtt tgtggtggat
      541 tatgttgttc agtcccaaat gtgtggagac tgccatagag tagaagctaa ggatttctgg
      601 aaggctgtga tccaagtcag gcagaagact ctgcacaaga aaacattcta ctatctggaa
      661 cagttaattc tgaaatatgg aatgcatcag aatactctgc gtatcaagga gattcatgat
      721 ggtctggatt tttattattc ttcaaaacag catgctcaga agatggtgga gtttcttcag
      781 ggtacagttc cctgtagata caaatcatca caaagattga tctcccagga tattcatagt
      841 aacacataca attacaagag tactttttct gtggaaattg ttccaatatg caaggataat
      901 gttgtctgtc tgtcaccaaa actggcacag agccttggaa atatgaacca gatatgtatt
      961 tgtatacgag taactagtgc catccatctc atagacccaa ataccttaca agttgcagac
     1021 attgatggga acaccttctg gagtcatcct ttcaatagtt tatgccatcc taaacagcta
     1081 gaagaattta ttgtgataga atgcagcata gtccgagatc tgaagcgaaa cgcgggggct
     1141 ggagtgatat caaagaagca cacccttggg gaagtctgga tccagaagac atctgaaatg
     1201 gatacagata aacagtattt ttgccggact cacttgggac atcttttaaa tcctggagac
     1261 ctggtgttgg gatttgattt ggccaactgt aacttaaatg atgagcatgt caacaaaatg
     1321 aaatcagata gagttccaga tgtggtcttg attaagaaga gctatgaccg taccaaacgc
     1381 cagcgccgta gaaactggaa actgaaagag cttgcaagag acagagaaga catggacaca
     1441 gatgatgaaa ggcaatatca agattttctt gaagatcttg aagaagatga gacaattaga
     1501 aaaaatgtca acatttacag agattcaacc gtccctgtgg aaagtgacac agatgatgaa
     1561 ggagcgcctc gaattagtct ggctgagatg cttgaagacc ttcgtatttc tcaagatgct
     1621 actggtgaag aaggtgcatc aatgatgtca tgatgagtca tatgctgttt gcatatctgt
     1681 gaacttagga agttggcaaa ataatcttga ttgtatagta catgtattcc cttatatttt
     1741 ggggtttttt tgtttgtttt tttccggagc tgaggactcc cttatatttt gaaaggagca
     1801 attttacctt aaacttgaat aaattactat tttgattgtt cacttaaa
//
