LOCUS       NM_012799               1583 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus neuromedin B receptor (Nmbr), mRNA.
ACCESSION   NM_012799 XM_218316
VERSION     NM_012799.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1583)
  AUTHORS   Li,P., Janczewski,W.A., Yackle,K., Kam,K., Pagliardini,S.,
            Krasnow,M.A. and Feldman,J.L.
  TITLE     The peptidergic control circuit for sighing
  JOURNAL   Nature 530 (7590), 293-297 (2016)
   PUBMED   26855425
  REMARK    GeneRIF: peptidergic pathways comprise the core of a sigh control
            circuit that integrates physiological and perhaps emotional input
            to transform normal breaths into sighs
REFERENCE   2  (bases 1 to 1583)
  AUTHORS   Kwitek,A.E., Gullings-Handley,J., Yu,J., Carlos,D.C., Orlebeke,K.,
            Nie,J., Eckert,J., Lemke,A., Andrae,J.W., Bromberg,S., Pasko,D.,
            Chen,D., Scheetz,T.E., Casavant,T.L., Soares,M.B., Sheffield,V.C.,
            Tonellato,P.J. and Jacob,H.J.
  TITLE     High-density rat radiation hybrid maps containing over 24,000
            SSLPs, genes, and ESTs provide a direct link to the rat genome
            sequence
  JOURNAL   Genome Res 14 (4), 750-757 (2004)
   PUBMED   15060019
REFERENCE   3  (bases 1 to 1583)
  AUTHORS   Giladi,E., Nagalla,S.R. and Spindel,E.R.
  TITLE     Molecular cloning and characterization of receptors for the
            mammalian bombesin-like peptides
  JOURNAL   J Mol Neurosci 4 (1), 41-54 (1993)
   PUBMED   8391296
REFERENCE   4  (bases 1 to 1583)
  AUTHORS   Wada,E., Way,J., Shapira,H., Kusano,K., Lebacq-Verheyden,A.M.,
            Coy,D., Jensen,R. and Battery,J.
  TITLE     cDNA cloning, characterization, and brain region-specific
            expression of a neuromedin-B-preferring bombesin receptor
  JOURNAL   Neuron 6 (3), 421-430 (1991)
   PUBMED   1848080
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_012799.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U37058.1, SRR26360176.403343.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMN06621351
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-553               JAXUCZ010000001.1  10954984-10955536
            554-902             JAXUCZ010000001.1  10961423-10961771
            903-1583            JAXUCZ010000001.1  10964875-10965555
FEATURES             Location/Qualifiers
     source          1..1583
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p13"
     gene            1..1583
                     /gene="Nmbr"
                     /gene_synonym="NMB-R"
                     /note="neuromedin B receptor"
                     /db_xref="GeneID:25264"
                     /db_xref="RGD:3181"
     exon            1..553
                     /gene="Nmbr"
                     /gene_synonym="NMB-R"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..1304
                     /gene="Nmbr"
                     /gene_synonym="NMB-R"
                     /note="neuromedin-B-preferring bombesin receptor"
                     /codon_start=1
                     /product="neuromedin-B receptor"
                     /protein_id="NP_036931.1"
                     /db_xref="GeneID:25264"
                     /db_xref="RGD:3181"
                     /translation="MPPRSLPNLSLPTEASESELEPEVWENDFLPDSDGTTAELVIRC
                     VIPSLYLIIISVGLLGNIMLVKIFLTNSTMRSVPNIFISNLAAGDLLLLLTCVPVDAS
                     RYFFDEWVFGKLGCKLIPAIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGVVLWT
                     SLKAVGIWVVSVLLAVPEAVFSEVARIGSSDNSSFTACIPYPQTDELHPKIHSVLIFL
                     VYFLIPLVIISIYYYHIAKTLIRSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFV
                     FCWFPNHILYLYRSFNYKEIDPSLGHMIVTLVARVLSFSNSCVNPFALYLLSESFRKH
                     FNSQLCCGQKSYPERSTSYLLSSSAVRMTSLKSNAKNVVTNSVLLNGHSTKQEIAL"
     exon            554..902
                     /gene="Nmbr"
                     /gene_synonym="NMB-R"
                     /inference="alignment:Splign:2.1.0"
     exon            903..1583
                     /gene="Nmbr"
                     /gene_synonym="NMB-R"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtggctcag ttccaggagc cacaaacttg ccaggatcag agacaatcaa ctaaacccag
       61 gtcgtactca ccgcactttc gagacgcgcg agtgcaggaa aactcccgcg aatcccctgg
      121 gaaaggacac catgcccccc aggtctctcc ccaacctctc cttgcccacc gaggcgagcg
      181 agagcgagtt ggaacccgag gtgtgggaaa atgatttcct gcctgactca gacgggacca
      241 ccgcggagtt ggtaatccgc tgtgtgatac catccctcta cctaatcatc atctcggtgg
      301 gcttgctggg caacatcatg ctggtgaaga tattcctcac caacagcacc atgcggagtg
      361 tccccaacat cttcatctct aacctggctg cgggagacct gctgctgctg ctgacctgcg
      421 tcccagtgga tgcctcccga tacttctttg atgaatgggt gttcggcaag ctgggctgca
      481 aactcatccc agccatccag ctcacctcgg tgggggtttc cgtgttcact ctcacggccc
      541 tcagcgctga caggtacaga gctatcgtga accccatgga catgcagacg tctggtgtgg
      601 tgctgtggac cagtttgaag gccgtgggca tctgggtggt ctctgtgctg ttggctgtcc
      661 ctgaggctgt gttttcggaa gtagcacgca tcggtagctc ggataacagc agtttcacag
      721 catgcatacc ctacccacaa acagatgagt tacatccaaa gatccactca gtgctcattt
      781 ttcttgtcta tttcctcata ccccttgtta tcatcagcat ttattattat cacattgcga
      841 agactttaat tagaagtgca cacaatcttc ctggagaata caatgaacat accaaaaagc
      901 agatggagac acggaaacgc ctggccaaga tcgttctggt gtttgtgggc tgctttgtct
      961 tctgctggtt tcccaaccac atcctctact tgtataggtc tttcaactac aaggagatcg
     1021 atccttctct tggacacatg attgtcacct tagtggcccg ggttctgagt ttcagcaact
     1081 cctgtgtcaa cccgtttgct ctttacctgc tcagtgaaag cttcaggaag catttcaaca
     1141 gccagctctg ttgtgggcag aagtcctatc ctgagaggtc taccagctac ctcctcagct
     1201 cttcagcagt aagaatgact tctctgaaaa gcaacgcgaa gaatgtggtg accaattctg
     1261 tcctgctcaa cggacatagc acaaagcaag aaatagcact gtgatcggag accatccaat
     1321 tcatcctcgg gaaataccat tttcgcagct tttccattat tattgagcga agcagagcta
     1381 aataatcacc acatttatac tgctccccag ctaattcatg attgactcaa gcgcaaggca
     1441 cgcacttttg tctgaataga aagaatttta ccttacacca cacacatcta actcacacgt
     1501 aattcacata tatctcctgc taacatcggt ttacacattc ccttgggatt taagacattc
     1561 caacaagcaa atgtggcata ttg
//
