LOCUS       NM_001169149            3012 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus NLR family, pyrin domain containing 9 (Nlrp9),
            mRNA.
ACCESSION   NM_001169149 XM_001072936 XM_218248
VERSION     NM_001169149.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3012)
  AUTHORS   Zhu,S., Ding,S., Wang,P., Wei,Z., Pan,W., Palm,N.W., Yang,Y.,
            Yu,H., Li,H.B., Wang,G., Lei,X., de Zoete,M.R., Zhao,J., Zheng,Y.,
            Chen,H., Zhao,Y., Jurado,K.A., Feng,N., Shan,L., Kluger,Y., Lu,J.,
            Abraham,C., Fikrig,E., Greenberg,H.B. and Flavell,R.A.
  TITLE     Nlrp9b inflammasome restricts rotavirus infection in intestinal
            epithelial cells
  JOURNAL   Nature 546 (7660), 667-670 (2017)
   PUBMED   28636595
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Dec 19, 2009 this sequence version replaced
            XM_218248.3, XM_001072936.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.848.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-271               JAXUCZ010000001.1  77370096-77370366   c
            272-1850            JAXUCZ010000001.1  77356931-77358509   c
            1851-2015           JAXUCZ010000001.1  77352575-77352739   c
            2016-2180           JAXUCZ010000001.1  77351441-77351605   c
            2181-2348           JAXUCZ010000001.1  77339916-77340083   c
            2349-2519           JAXUCZ010000001.1  77336726-77336896   c
            2520-2690           JAXUCZ010000001.1  77324424-77324594   c
            2691-2861           JAXUCZ010000001.1  77323697-77323867   c
            2862-3012           JAXUCZ010000001.1  77320034-77320184   c
FEATURES             Location/Qualifiers
     source          1..3012
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     gene            1..3012
                     /gene="Nlrp9"
                     /gene_synonym="Nalp9a; Nalp9b; Nlrp9b"
                     /note="NLR family, pyrin domain containing 9"
                     /db_xref="GeneID:292577"
                     /db_xref="RGD:1308981"
     CDS             1..3012
                     /gene="Nlrp9"
                     /gene_synonym="Nalp9a; Nalp9b; Nlrp9b"
                     /note="NACHT, LRR and PYD containing protein 9b; NLR
                     family, pyrin domain containing 9B; NACHT, LRR and PYD
                     containing protein 9a"
                     /codon_start=1
                     /product="NACHT, LRR and PYD domains-containing protein 9"
                     /protein_id="NP_001162620.1"
                     /db_xref="GeneID:292577"
                     /db_xref="RGD:1308981"
                     /translation="MVDTSGYGLLKHLRKLSDGEFWSFKELLRKEPEKFKLKPISWMK
                     IENASKEELVMLLNTHYPKQAWDMALSLFLQVNREDLSIMAQKKRRYKQTKYKKFMKT
                     TFQSIWTLESNICIPDRSYHLIVEHQYRKLQNIFDSESEPVTAVVTGPTGEGKTVFLR
                     KAMLDWASGILWQNRFQYVFFFSVLSLNNTTELSLAELISSKLPESSETLNDILSDPK
                     KILFILDGFDYLKFDLELRTNLCNDWRKILPTQIILSSLLQKIMLPESSLLLELGHIS
                     LPKIFPLLQYPRDITIQGFSERCLKTYFISFFNTEKGIEVFENLKSNQMLKLCSNPYL
                     CWMFCSCLKWQFDREEEAYFQAKTDSVFFTSFMVSAFKSAYASNPPKQNRAQLKSLCT
                     LAVEGMWKQLFVFDSEDLRRNGISESDKAVWLRMKFLQNHDNHIVFYHPTLQLYFASM
                     FYFLKQDKDTHVPVIGSIPQLLRKIYARDHTQWLQIGIFLFGLATEQVASLLKPYFGF
                     IQHRDVRQEVMRYLKSLSQRECCEKLERPQNLFACLRDNKEEKFVREVVDLFEEITVD
                     ITNSHVLSIIANHLQKSSKLKKLHLHIQKRVFLEIHDPEYSDSETFTQDKKNAAEYWK
                     KLCHIFVNLHVLDLDSCNFNKQVIEELCNVLSPSPKIPLMAFKLESLLCSFMTNFGDG
                     SLFHTLLQLPHLKYLNLYGTNLSNSRIENLCSALRRSTCKVEELLLGKCDISSEACGI
                     IATSLMNSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLETLMLSYCCLTFIACGHLY
                     EALVSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCILKELWLSGCFLTSECCEEISA
                     VLTCNNNLKTLKLGNNDIEDTGVKHLCEALSHPNCKLECLGLDLCKFTSDCCEDLASA
                     LTTCKTLNSLNLDWKTLEHSGVVALCEALNHKKCNLKMLGLDKSAFSVESQTLLQAVE
                     KKNNNLSILHYPWVEEERKKRGVRLVWNSKN"
     exon            1..271
                     /gene="Nlrp9"
                     /gene_synonym="Nalp9a; Nalp9b; Nlrp9b"
                     /inference="alignment:Splign:2.1.0"
     exon            272..1850
                     /gene="Nlrp9"
                     /gene_synonym="Nalp9a; Nalp9b; Nlrp9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1851..2015
                     /gene="Nlrp9"
                     /gene_synonym="Nalp9a; Nalp9b; Nlrp9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2016..2180
                     /gene="Nlrp9"
                     /gene_synonym="Nalp9a; Nalp9b; Nlrp9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2181..2348
                     /gene="Nlrp9"
                     /gene_synonym="Nalp9a; Nalp9b; Nlrp9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2349..2519
                     /gene="Nlrp9"
                     /gene_synonym="Nalp9a; Nalp9b; Nlrp9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2520..2690
                     /gene="Nlrp9"
                     /gene_synonym="Nalp9a; Nalp9b; Nlrp9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2691..2861
                     /gene="Nlrp9"
                     /gene_synonym="Nalp9a; Nalp9b; Nlrp9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2862..3012
                     /gene="Nlrp9"
                     /gene_synonym="Nalp9a; Nalp9b; Nlrp9b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggtggaca cgtctggata tggcttgctg aagcatctgc gaaaactgag tgacggggag
       61 ttctggagct ttaaagagct tctcaggaaa gagccagaga aatttaagct caaaccaata
      121 tcctggatga aaattgagaa tgcttccaaa gaagaactgg taatgctatt gaacacacat
      181 tatccaaaac aggcatggga tatggcgttg agcctgtttc tacaggtcaa tcgggaagac
      241 ctctcaatca tggctcagaa aaagaggaga tataaacaaa ctaaatataa aaagtttatg
      301 aagactacat ttcaaagcat atggacattg gagagcaaca tttgtatacc tgatagaagc
      361 taccatttaa ttgtagaaca ccagtacaga aaactgcaga acatatttga ttctgaatca
      421 gagccagtca ctgcagttgt aacaggtcca acaggagaag gaaaaaccgt tttcctgaga
      481 aaagcaatgt tggattgggc atcaggaatt ttatggcaga accggtttca atatgttttc
      541 tttttctctg tcctctcact taacaatacc acagagttaa gcttagctga gcttatctca
      601 agtaagttac ctgagtcttc agagacactg aatgacattt tatctgatcc aaagaaaatc
      661 ttgtttatcc tggatggatt tgattacctg aaatttgact tggaactcag gacaaacttg
      721 tgtaatgact ggaggaagat attgccaaca caaatcatct tgagtagttt actacagaaa
      781 ataatgctcc cagaatcctc tttgcttctt gaattaggac atataagttt accaaaaatc
      841 ttccctttgc tgcagtatcc aagggacata actatccaag gattctctga gcggtgtcta
      901 aagacctatt ttatatcctt cttcaatact gaaaaaggca tagaagtctt tgagaatttg
      961 aagtctaatc aaatgctcaa attatgcagc aatccttatc tatgctggat gttctgtagt
     1021 tgtttaaagt ggcagtttga cagggaagag gaagcgtact ttcaggctaa aacagattcg
     1081 gtcttcttca caagctttat ggttagtgca ttcaaatcag catatgccag taatccacct
     1141 aaacaaaaca gagcccaatt aaagagcctg tgtaccttgg ctgtagaagg aatgtggaaa
     1201 cagttgtttg tttttgactc tgaagatctc aggaggaatg gtatatctga atcagataag
     1261 gcagtgtggc tgagaatgaa atttctccag aatcatgata accacattgt gttttatcat
     1321 cctacactac agttatactt tgcttccatg ttctatttcc tcaaacaaga caaagacacg
     1381 catgtcccag tcattggaag catacctcaa ctcctaagaa aaatttatgc tcgtgaccac
     1441 acacaatggc tccagatagg gatttttttg tttggactcg ccactgagca agttgcctcc
     1501 ttgctcaaac catactttgg ctttatacag cacagagatg taagacagga agtcatgaga
     1561 taccttaaga gtctcagtca acgagagtgc tgtgagaaat tggaaagacc ccagaatttg
     1621 tttgcctgtc tacgtgacaa caaggaggaa aaatttgtaa gagaagtggt agatctattt
     1681 gaagaaatta ctgttgatat tactaattca catgtattgt caataattgc aaaccatctt
     1741 cagaaatcct ccaaattaaa gaaacttcac ctgcatatac aaaagagagt ttttttagaa
     1801 attcatgacc cagaatatag tgactcagaa acctttacac aggacaaaaa aaatgcagct
     1861 gaatattgga agaagttatg tcatattttt gtcaacttac atgtgttgga tctggacagc
     1921 tgtaatttca acaaacaggt catagaggaa ctctgtaatg tgctgtctcc atcacctaag
     1981 atacctctga tggcttttaa gctcgaaagc ttgttgtgtt cattcatgac taactttgga
     2041 gatggttcac tatttcacac ccttcttcag ctacctcacc tgaaatacct aaacctgtat
     2101 ggcaccaacc tctccaacag taggattgag aatctgtgct ctgctctgag acgctcaaca
     2161 tgcaaagtag aggaactact gttgggtaaa tgtgacatat caagtgaggc atgtggcata
     2221 attgctactt cccttatgaa ctctaaagtg aaacatctct cattggttga aaatcccttg
     2281 aagaacaaag gagtgatgtc actgtgtgaa atgctgaagg atccaagctg tgtccttgag
     2341 acactgatgt tgtcttactg ctgtctcaca ttcattgcct gtggccatct ctatgaagcc
     2401 cttgtgagca ataaacacct ctccctgctt gatctggggt caaatttcct ggaagatact
     2461 ggagtgaacc ttctgtgtga agctttgaaa gacccaaact gcatcctcaa ggagttatgg
     2521 ttgtcaggtt gctttttaac ttcagaatgc tgtgaggaga tctctgctgt cctgacttgc
     2581 aataataatc taaagaccct gaaactgggc aacaatgaca tagaagacac tggtgtcaaa
     2641 catttatgtg aagccctgag tcatcctaac tgtaaattag aatgtcttgg gttagacctg
     2701 tgcaagttca caagtgactg ttgtgaagac ctggcctcag ctctcaccac ctgcaaaaca
     2761 ctgaatagct taaatctgga ctggaaaacc ttggaacact ctggagtcgt ggctctctgt
     2821 gaggctttga atcacaagaa atgtaacttg aagatgcttg gactggacaa atctgcattt
     2881 tctgtggaat cgcagacatt actgcaagct gtggaaaaga aaaacaataa tctgagtatt
     2941 ttacattatc cctgggttga agaggaacgc aagaagaggg gtgttcgtct ggtctggaac
     3001 agcaagaatt ga
//
