LOCUS       XM_008767925            3787 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus NLR family, pyrin domain containing 1B
            (Nlrp1b), mRNA.
ACCESSION   XM_008767925
VERSION     XM_008767925.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051345.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XM_008767925.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3787
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3787
                     /gene="Nlrp1b"
                     /note="NLR family, pyrin domain containing 1B; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 11 Proteins, and 82% coverage of the annotated genomic
                     feature by RNAseq alignments, including 18 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:691998"
                     /db_xref="RGD:1593294"
     CDS             1..3363
                     /gene="Nlrp1b"
                     /codon_start=1
                     /product="NACHT, LRR and PYD domains-containing protein 1b
                     allele 3-like"
                     /protein_id="XP_008766147.2"
                     /db_xref="GeneID:691998"
                     /db_xref="RGD:1593294"
                     /translation="MKQKGENIHSTQPLKRENVFRNFTNLLLFRKFCPRDSEKLVRKS
                     WHSCVPEEGGHMIEIQDLFDPNSDTEKRPQLVIVEGAAGIGKSTLARQVRRAWKEGQL
                     YRDRFQHVFFFSCRELAQCKQLSLAELIAQGQEVPTAPIRQILSRPKKLLFILDGIDE
                     PAWVLEDQNPELCVHWSQAQPVHTLLGSLLGKSILPEASLMLTARTTALQKIIPSLGQ
                     PNQVQVLGFTEVERENYFYRYFAKQRVAMTAHMKLQSNPVLQTLCEVPWVCWLVCACL
                     EKQMQQGEVLSLTSQTTTALCLKYLSLTIPGQHLSTQLRTLCSLAAEGICQRRTLFSK
                     SDLCKQGLARNAINTFLEIGVLQRQPSSLSYSFAHLCLQEFFAAMSYILEDSEERHGD
                     MGNDRTVETLVERYGRQNLFEAPTVRFLFGLLSEEGLKEMEKFFSCNLLRKTKLELLW
                     HILAKFQSHQPHSLGFLRCLYENQETQLLSHVMHDLQGIIVPDTNDRAHSVIQTNVKH
                     LVIQTDMELMVVTFCIQFCYHVRSLQVNMERQQGYELTAPRMVLHRWTPITDASWKIL
                     FSNLKFTRNLEELDLSGNPLSYSAVCSLCKALKQPDCQLKSLWLVECGLTSRCCSLLA
                     EVLSAHSRLTELDLQVNDLGDNGVRLLCKGLRSPACNLSILRLDQASLSDQVIMELRD
                     LEAKNPKLRISSTWMPHMMVPTENMDGEDIMDSFKQQRQQSRETLMETLGTEDDFWGP
                     SGPVSTEVVDRERNLYRVQLPMAGVYHCPSTGLHFVVTRAVTIQIEFCAWSQFLDKTP
                     LQHRYMVAGPLFDIKAEQGAVTAVYLPHFVSIQDPKASTFDFKVAHFQEHGAVLETPV
                     RVKHRYAALKNPSFSPLGVVLRIIPAARRFIPITSITLIYYHLSLEEVTLHLYLIPND
                     CTIQKAIDEEEKKFQFVRIHKPPPVDSLYIGSRYIVSGSEKLEITPKELELCYRSSKE
                     FQLFSEIYVGHMGSEIKLQIKDKKHTQLIWEALLKPGDLRPALPRIAPATKDAPALLH
                     FMDQHREQLVARVTSVDPLLDKLHSLVLSEDSYEAVRAETTNQDKMRKLLSLSRAWSR
                     AGKDQFYNALKETHPHLVMDLLEMSGGVSLRY"
ORIGIN      
        1 atgaaacaaa aaggggagaa tattcactcc actcagccat tgaaaaggga gaatgtgttc
       61 cgaaatttta caaacctact actcttccga aaattttgcc caagagattc agagaaattg
      121 gtcaggaaaa gctggcattc atgtgtacca gaagaaggag gacatatgat tgagatccaa
      181 gacttatttg acccaaattc agatactgag aaaagacctc aattagtcat agtagagggg
      241 gctgctggga ttgggaagtc aacactggcc aggcaggtga ggagagcctg gaaggagggc
      301 cagctctaca gggatcgctt ccagcatgtc ttcttcttca gctgcagaga gctggcccag
      361 tgcaagcagc tgagtctggc tgagctcata gcacaaggcc aggaagtgcc cacagctccc
      421 atcagacaga tcctgtctcg ccctaagaag ctgctcttca tcctggatgg catagatgag
      481 ccagcatggg tcttggagga ccagaatcct gagctgtgtg tgcactggag tcaagcacaa
      541 cctgtgcaca cactcctggg gagtttgctg gggaaatcca tccttcctga ggcttcctta
      601 atgctcacag ctcggaccac agctctacaa aaaatcattc cttctctggg gcagccaaat
      661 caagttcaag tcctaggatt cactgaggtt gaacgggaga actatttcta cagatatttt
      721 gcaaagcaaa gagttgcaat gaccgctcat atgaagcttc aatctaaccc agtgcttcag
      781 accctgtgtg aggtcccctg ggtgtgctgg ttggtctgcg cttgcctgga aaagcagatg
      841 cagcagggtg aagtactctc actgacctca cagaccacca cagccctctg cctgaaatac
      901 ctttccctga caattccagg tcagcacctg agcacccagc ttaggaccct ctgttcactg
      961 gctgctgagg ggatctgcca aagaaggacc ctgttcagta aaagtgacct ctgtaagcaa
     1021 gggttagcaa ggaatgccat taacactttc ctggagatcg gtgtccttca aaggcagccc
     1081 agctctctga gctacagctt tgcccacttg tgtctccagg agttctttgc agcgatgtcc
     1141 tacatcttgg aggatagtga ggaaagacat ggggatatgg gaaacgacag aactgtggaa
     1201 acactggtag aacggtatgg aagacaaaac ctgtttgagg cacccactgt gcgctttcta
     1261 tttggtcttt tgagtgaaga gggattgaaa gaaatggaaa agttcttttc ctgcaacctt
     1321 cttaggaaga caaagttgga attactatgg cacatccttg caaaattcca atcccatcaa
     1381 ccgcattctc tgggttttct acgctgtctg tatgaaaatc aggaaacgca gctcctatca
     1441 cacgtgatgc atgatcttca aggaataata gtgcctgaca caaatgatag ggcacactca
     1501 gtgatccaga caaatgtgaa gcacttggtg atacagacag acatggagct catggtggtc
     1561 actttctgta ttcagttctg ctatcatgtg aggagccttc aggtgaatat ggaaagacag
     1621 caaggatatg agttgacagc cccaaggatg gttctgcaca ggtggacccc aatcactgat
     1681 gccagttgga agattttatt ctccaatctt aaattcacca gaaacctgga ggagctggac
     1741 ctaagtggaa atccactgag ctactctgca gtatgcagtc tctgtaaggc cctgaaacag
     1801 cctgactgcc aactaaagag cttgtggctt gttgaatgtg gcctcacatc cagatgctgt
     1861 tcactcctgg ccgaagtgct cagtgcccac tccaggctga ctgagctaga cctgcaggtg
     1921 aatgacctgg gtgacaatgg tgtgaggctg ctgtgtaagg gactcaggag tcctgcctgc
     1981 aacctcagca tcctgcggtt ggaccaggcc tctctcagtg accaggtgat tatggagctc
     2041 agagacttgg aggcaaagaa tccaaagcta cgaatctcca gcacatggat gccacacatg
     2101 atggtcccca ctgagaacat ggatggagaa gatatcatgg actcattcaa acagcagaga
     2161 caacagtcaa gagagacact catggaaact ctgggaactg aagatgactt ctggggccct
     2221 tcaggacctg tgtctactga ggtggttgac agagagagga acctgtaccg agtgcaattg
     2281 cccatggctg gtgtctacca ctgtcccagc acaggactac actttgtggt gacaagggca
     2341 gtgacaatac agatcgaatt ctgtgcctgg agtcaattcc tggacaagac tcccttacaa
     2401 cacagataca tggtagctgg acctctgttt gacatcaagg ctgagcaagg agctgtgact
     2461 gctgtgtacc tccctcattt tgtgtccatc caagacccaa aggcaagcac atttgacttc
     2521 aaggtggccc actttcaaga acatggggcg gttctagaaa cgccagttag ggtgaagcat
     2581 cgctatgcag cactgaaaaa cccaagcttc tcgccattag gagttgtgct gagaataatc
     2641 cctgctgccc ggcgcttcat ccccatcact tccatcacac tgatctacta tcacctcagt
     2701 cttgaagagg tcacccttca cctctacctc atccccaatg actgcaccat tcagaaggcc
     2761 attgatgagg aagaaaagaa gtttcagttc gtgagaatac acaagccacc cccagtagat
     2821 agcctgtaca tcggctcccg ctacatcgtg tctggttctg agaagctgga aatcaccccg
     2881 aaggaactgg agctatgcta caggagcagc aaggaattcc agctcttctc tgagatctat
     2941 gttggacaca tgggttcaga gattaagctg caaatcaaag acaagaagca cacgcaactc
     3001 atatgggagg ccttgctgaa accaggagac ctcagacctg cactgcccag gattgctcca
     3061 gccacaaaag atgctcctgc cctgctacac ttcatggacc agcatcggga gcagctggtg
     3121 gcccgagtga catcagtgga ccctctcttg gacaagctgc atagtctggt gctgagtgaa
     3181 gattcctatg aggcagtgag ggctgaaacc acaaaccaag acaagatgag gaagctgtta
     3241 agcctcagcc gggcctggag tcgagccggc aaagaccaat tctacaacgc tctgaaggag
     3301 acccatcctc acctggtcat ggatctgctt gagatgtcgg gtggagtctc tttgagatac
     3361 tgacatcctg tctgagggcc tttttgagac aatgttttgc tgtgcagtcc ttgctgtcct
     3421 gaaatacact ctgtagacca gggtgcactt gaaccctcag tgaagagatc catttgcctc
     3481 ggctacctga gggctgggaa taaagccatg tgccaacacc atccagccaa acaatgtctt
     3541 tatccctctt catcattgtg tcagttctcg atcctataca cttgtccata aggtcaagta
     3601 gtaggagttg caggggattc gtggtggcgt tagctaacat gatcaccccg gaagtctagt
     3661 ctttaaccag tgagcagtgc ttccttcaag gtgtgaccct catgattgct ttgggcaatg
     3721 tataaactgg tgaaaaagac cagacctatg aatcctcctc agctccctct tgcagcctgc
     3781 attcagc
//
