LOCUS       NM_001106732            1078 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus NK2 homeobox 8 (Nkx2-8), mRNA.
ACCESSION   NM_001106732 XM_001079326 XM_234179
VERSION     NM_001106732.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1078)
  AUTHORS   Tian J, Mahmood R, Hnasko R and Locker J.
  TITLE     Loss of Nkx2.8 deregulates progenitor cells in the large airways
            and leads to dysplasia
  JOURNAL   Cancer Res 66 (21), 10399-10407 (2006)
   PUBMED   17079460
REFERENCE   2  (bases 1 to 1078)
  AUTHORS   Dillon AK, Fujita SC, Matise MP, Jarjour AA, Kennedy TE, Kollmus H,
            Arnold HH, Weiner JA, Sanes JR and Kaprielian Z.
  TITLE     Molecular control of spinal accessory motor neuron/axon development
            in the mouse spinal cord
  JOURNAL   J Neurosci 25 (44), 10119-10130 (2005)
   PUBMED   16267219
REFERENCE   3  (bases 1 to 1078)
  AUTHORS   Kajiyama Y, Tian J and Locker J.
  TITLE     Regulation of alpha-fetoprotein expression by Nkx2.8
  JOURNAL   Mol Cell Biol 22 (17), 6122-6130 (2002)
   PUBMED   12167706
REFERENCE   4  (bases 1 to 1078)
  AUTHORS   Apergis GA, Crawford N, Ghosh D, Steppan CM, Vorachek WR, Wen P and
            Locker J.
  TITLE     A novel nk-2-related transcription factor associated with human
            fetal liver and hepatocellular carcinoma
  JOURNAL   J Biol Chem 273 (5), 2917-2925 (1998)
   PUBMED   9446603
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473947.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_234179.4, XM_001079326.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN16676784,
                              SAMN16676785 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1078
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q23"
     gene            1..1078
                     /gene="Nkx2-8"
                     /gene_synonym="Nkx2-9"
                     /note="NK2 homeobox 8"
                     /db_xref="GeneID:299061"
                     /db_xref="RGD:1310629"
     exon            1..372
                     /gene="Nkx2-8"
                     /gene_synonym="Nkx2-9"
                     /inference="alignment:Splign:2.1.0"
     CDS             225..929
                     /gene="Nkx2-8"
                     /gene_synonym="Nkx2-9"
                     /note="NK2 transcription factor related, locus 9"
                     /codon_start=1
                     /product="homeobox protein Nkx-2.8"
                     /protein_id="NP_001100202.1"
                     /db_xref="GeneID:299061"
                     /db_xref="RGD:1310629"
                     /translation="MASSGRLGFTVRSLLNLPEQDAQPRVRCEQQTCVPQTAAWLESE
                     RSHYPSSDESGLETSPADSSQLASLGRASPGSDAEKRRKRRVLFSKAQTLELERRFRQ
                     QRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLKRGRAPGVTESSDVTASADLHAAP
                     GLLRRVVVPVLVHDRSPCNGRGEGTAAVPQDKCSSRLATACPVQGYTAFGPGSALGLF
                     PAYQHLAPPALVSWNW"
     exon            373..1078
                     /gene="Nkx2-8"
                     /gene_synonym="Nkx2-9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cactcattca ggtacttaag accccggaca cccggaccgt ggctttcaaa gcccaccgag
       61 tggcaagggc tgtttataaa aacagggatt cctccgcaaa ggcgctgata acctgaggcc
      121 agcgcatggc gagcgcctcc cacttccatc cttaggagcg gcgtccccag gcgtccctgg
      181 gttcctagcc tgccctgccc cccaccttct tcccctcctg ggccatggcc tcctctggac
      241 gcctcggctt caccgtgcga agcctcctga atttacccga acaggatgcg cagcccaggg
      301 tgaggtgcga gcaacagacg tgcgttcctc agacggccgc ctggctggag tcggagcgca
      361 gccactaccc gtcctctgat gaaagcggcc tggagactag ccctgcagac tcgtcgcagc
      421 tggcttccct cgggcgggcg tcccctggct ccgacgcaga gaagaggagg aagcggcggg
      481 tgctgttctc caaggcccag actttggagt tggagcggcg ctttcggcag cagcggtacc
      541 tgtcggcgcc cgagcgggaa cagctggctc gacttctgcg cctcacgccc acgcaggtca
      601 agatctggtt ccagaaccac cgctacaagc tgaagcgtgg gcgagcgcca ggggtcacag
      661 aatcttcgga tgtgacagca tcagctgatc tgcacgccgc tcccggcctg ctgcgccgcg
      721 tagtggtacc cgtgctggtt cacgaccgat caccgtgcaa tggcaggggt gaggggaccg
      781 ctgcggtgcc ccaggacaag tgcagctcac gcctggccac tgcgtgccca gtgcaaggtt
      841 acactgcctt cggaccgggc tcagcattag gcctcttccc tgcctaccag cacttagcac
      901 caccagctct ggtctcctgg aactggtgag gctgctgcga ggtgcctaga gccgccctag
      961 gcttgggaca ttgctgtttg gcctgccgca gtagcgctac agccgcacca aactcaggaa
     1021 gtgacccttg caggatccac tcttgagtcc tgggtccctg ggttgctcta accagcaa
//
