LOCUS       XM_006240118            2721 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus NK2 homeobox 1 (Nkx2-1), transcript
            variant X3, mRNA.
ACCESSION   XM_006240118
VERSION     XM_006240118.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051341.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XM_006240118.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2721
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2721
                     /gene="Nkx2-1"
                     /gene_synonym="Titf1; TTF1"
                     /note="NK2 homeobox 1; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 2 mRNAs, 8 ESTs, 14
                     Proteins, and 96% coverage of the annotated genomic
                     feature by RNAseq alignments, including 15 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:25628"
                     /db_xref="RGD:3866"
     CDS             457..1575
                     /gene="Nkx2-1"
                     /gene_synonym="Titf1; TTF1"
                     /codon_start=1
                     /product="homeobox protein Nkx-2.1 isoform X3"
                     /protein_id="XP_006240180.1"
                     /db_xref="GeneID:25628"
                     /db_xref="RGD:3866"
                     /translation="MSMSPKHTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQG
                     QAAPPAAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVGGYCNGNLGNVSELPPYQD
                     TMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGDVSKNMAPLPSAP
                     RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKR
                     QAKDKAAQQQLQQDSGGGGGGGGGAGCPQQQQAQQQSPRRVAVPVLVKDGKPCQAGAP
                     APGAASLQGHAQQQAQQQAQAAQAAAAAISVGSGGAGLGAHPGHQPGSAGQSPDLAHH
                     AASPAALQGQVSSLSHLNSSGSDYGAMSCSTLLYGRTW"
ORIGIN      
        1 tgctagccgg atgagaggcg cccaattgaa gcagaatgat cctcatctac taatatccag
       61 cgtagccaca aagcaaccgg ccatttacgc cgccacttta gacaaagata tttggttatt
      121 cccggggaag cgagtgcact tttgcatggc tgtgctccgg gaggaggcga gcctcagccc
      181 agcctcccgc ccgctgggct gcgggcttcg aaatattcgc ctcctcccgg acaacgagtt
      241 ccaccggggt tcagactcaa ttccactctg caacggacct gagggctctc acgcggctcc
      301 ccgcccgggc tttccttgaa gcatcgaagg gggaaacggc ggggatctca actggggtgc
      361 tgggactggg atgtcctcgg aaagacagca ccagcttctg aagccgaagt atccaggcca
      421 tgggcaaggg tcgggggcac cagccgacgc cgaatcatgt cgatgagtcc aaagcacacg
      481 actccgttct cagtgtctga catcttgagt cccctggagg aaagctacaa gaaagtgggc
      541 atggagggcg gcggcctcgg ggctccgctc gcagcttaca gacagggcca ggcggccccg
      601 ccggccgcgg ccatgcagca gcacgccgtg gggcaccacg gcgccgtcac cgccgcctac
      661 cacatgacgg cggcgggggt gccccagctc tcccactccg ccgtgggggg ctactgcaac
      721 ggcaacctgg gcaacgtgag cgagctgcca ccttaccagg acaccatgcg gaacagcgct
      781 tcgggccccg gatggtacgg cgccaaccca gatccgcgct tccccgccat ctcccgcttc
      841 atgggcccgg cgagcggcat gaatatgagc ggcatgggcg gcctgggctc gctgggggac
      901 gtgagcaaga acatggcccc gctgcccagc gcaccccgcc ggaagcgtcg ggtgctcttc
      961 tcccaggcgc aggtgtacga gctcgagcga cgcttcaagc agcagaagta cctgtcggcg
     1021 ccggagcgcg agcatctggc cagcatgatt cacctgacac ccacgcaggt caagatctgg
     1081 ttccagaacc accgctacaa gatgaagcgc caggcgaagg acaaggcggc gcagcagcaa
     1141 ctgcagcagg acagcggcgg cggcggaggc ggcggcggcg gcgcgggttg cccgcagcag
     1201 cagcaagctc agcagcagtc gccgcgccgg gtggccgtgc cggtcctggt gaaagacggc
     1261 aaaccctgcc aagcgggcgc ccctgcaccg ggagccgcca gcctgcaagg ccacgcgcaa
     1321 caacaagctc agcagcaggc gcaggcggca caagcggctg ccgcggccat ctctgtgggc
     1381 agcggtggtg cgggtctagg agcacaccca ggccaccagc ccggcagcgc agggcagtcc
     1441 ccggacctgg cgcaccacgc agccagcccc gcagcgctgc agggccaggt ctctagccta
     1501 tctcatctga actcctctgg ctcggactat ggcgccatgt cttgctctac tttgctttat
     1561 ggtcggacct ggtgagatgt gggacgcgcc tgagccctgt gcgacctcac cgctttccct
     1621 ctaccctccg caaagaccac cattcgcccg ctgctccacg cccttctact tttttctcat
     1681 gtttagacca aggaaaagta cacaaagacc aaactgctgg actccttctt cttcttcttc
     1741 ttcttcttct tcttcttctt cttcttcttc ttcttcttct tcttcttctt cttcttcttc
     1801 ttcttcttct tcttcttctt cttcttcttc ttttcttctt cttcttcttc tccttcttct
     1861 ttttctgctt cttcttcttc ttcctcttct tcctcttctt cctcctcctc cttcttcctc
     1921 ctttttctcc ttgtccccac tcctcctttt ctctttctcc ttttcctacg tttccccttt
     1981 ttttccttca tccttctccc tttcctttct ctttcctacc taaaacttgt ggactttttt
     2041 ttaacataaa aagaaaatag aaacagtcaa gcaaatccaa cccctttacg aattctttaa
     2101 ccagagaagg acaaagaaca aatttggggg tctttctggt agttcaaatg ggttctcaag
     2161 cttaggcatg gcacaatttt ggggcctgct ctatgcttcc acggccctga actctgaagc
     2221 cggaaaactt ccctgtggat gcactctgcc agcaaagaga gcttgcttgt aaataccagg
     2281 atttttcgtt tgtttgtttc agaagggagg acagaaactg gagagaggaa agattcttca
     2341 gcataaccca cttgtccctg acacaaagga agtgtcccct cccaggtgcc ctctggccct
     2401 ataggttcag tccaggctgg cctttcagaa aattgtttta ggtttgatgt gaacttgtag
     2461 ctgtaaaatg ctgtcaaaag ttggactaaa tgcctagttt ttagtaacct gtacattatg
     2521 ttgtaaaaag aactccagtc ccagtccctg gcccctcact ttttaaaagg gcatcatgga
     2581 caagcctgtg tatattactc cacggtttgg tatttgcagc accagttgcc ccctcccttt
     2641 tttctgttgt aacttatgta gatatttggc ttaaatatag ttcctaagaa gcttctaata
     2701 aattatacga atttaaaaag a
//
