LOCUS       NM_001402224            5734 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus NFKB repressing factor (Nkrf), mRNA.
ACCESSION   NM_001402224 XM_003752133
VERSION     NM_001402224.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5734)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 5734)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 5734)
  AUTHORS   Nourbakhsh,M. and Hauser,H.
  TITLE     Constitutive silencing of IFN-beta promoter is mediated by NRF
            (NF-kappaB-repressing factor), a nuclear inhibitor of NF-kappaB
  JOURNAL   EMBO J 18 (22), 6415-6425 (1999)
   PUBMED   10562553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Mar 8, 2022 this sequence version replaced XM_003752133.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.63102.1,
                                           SRR26643429.59787.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN14984031 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-699               JAXUCZ010000021.1  121009553-121010251 c
            700-830             JAXUCZ010000021.1  120998216-120998346 c
            831-5734            JAXUCZ010000021.1  120992038-120996941 c
FEATURES             Location/Qualifiers
     source          1..5734
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq34"
     gene            1..5734
                     /gene="Nkrf"
                     /note="NFKB repressing factor"
                     /db_xref="GeneID:100910054"
                     /db_xref="RGD:6500424"
     exon            1..699
                     /gene="Nkrf"
                     /inference="alignment:Splign:2.1.0"
     CDS             428..2788
                     /gene="Nkrf"
                     /note="NF-kappa-B-repressing factor-like; NF-kappaB
                     repressing factor"
                     /codon_start=1
                     /product="NF-kappa-B-repressing factor"
                     /protein_id="NP_001389153.1"
                     /db_xref="GeneID:100910054"
                     /db_xref="RGD:6500424"
                     /translation="MAGGRLLLGGDFLSPPPLPPLPPPPPPLPPLPPPPPEPVLEQWR
                     YSHESDWQWALRRSFICRHLHSYPGAALDQLLALSAAWTNHVFLGCRYSPRLMEKILH
                     MAEGIDIGEMPSYDLMLPKPSKGQKRYLSTYDGQNPPKRQAGSKFHVRPRFEPVHFVA
                     SSSKAERQEDPYGPQTEEVNGRTHFASMPRNFYQDYTQDSFSIQDGNSQYCNSSGFIF
                     TKDQPVATNMYFDSGNPAPSSASQQANCQPAPEPPPSQMYPESVVAEKQYFIEKLTAT
                     IWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTD
                     GYACEVRCQNIYLSTGYAGSKNGSRDRATELAVKLLQKRIEVRVVRRKFKHIIGEDLV
                     VCQIGVLSYEFPPALKPPEDLVVLGKDASGQPIFNSSAKHWTNFVITENANDAIGILN
                     NSASFNKMSIEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKVLQKT
                     QPTYSSVKSSQCHSGSSPKGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVY
                     ERMTGLRWKCKVILESEVIAEAVGVKKSVKYEAAGEAVKTLKKTQPTVINNLKKGTVE
                     DVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQH
                     KREGLGLDVERVNKIAKRDIEQIIRNYARSESHSDLTFSTELTNDERKQIHQIAQKYG
                     LKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN"
     exon            700..830
                     /gene="Nkrf"
                     /inference="alignment:Splign:2.1.0"
     exon            831..5734
                     /gene="Nkrf"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcacaacct cggggtggca cgagggaggt agggtgagag atctgagccg gggaacccac
       61 cgtgctggtg cttcttcctc ctcttcttct tttttttttc cttgccgcta ttctctcagt
      121 gtgtgggtct aagggtcggc tgtgtggcag gacccaactc cgctgcctag tgtgccccat
      181 atataaggaa accctcacgt tcccacatta gttggagcgg tgtggccggc gtggcgacag
      241 ccaccgttga ccccccactc ccgtttccct gtaagcctag tcccccaggc acacactccg
      301 gtcccccgag actcggtccc gagcgcccct cacacacagg tctcccccga ccccagccac
      361 ctcgcttgct cgcggccagt ttgtaggcat cgtccctggg gggcgtcccc actctgaagc
      421 agagaagatg gctggaggac gtctgttgct ggggggggac ttcctgtcgc cgccgccgct
      481 gcccccccta ccgccgccgc cgccgccgct gccgccccta ccgccgcccc cgcctgagcc
      541 agtgctggag cagtggcgct atagccacga aagtgactgg cagtgggctc tgcggcggag
      601 cttcatctgc cggcacctgc acagctatcc cggggctgcc ctggaccagc tcctcgcgct
      661 ctccgccgcc tggaccaacc acgttttcct gggctgcagg tatagcccac gcttgatgga
      721 aaaaattctt cacatggctg aaggtattga tattggggag atgccgtcat atgatctgat
      781 gctgcccaaa ccttccaaag gccaaaaacg ctacctttca acctacgatg gtcagaatcc
      841 tcctaaaagg caagctggtt ccaaattcca tgtgagacct cgctttgagc ctgtccattt
      901 tgtagctagt agttcaaaag ccgaaagaca ggaagaccca tatggccccc aaacagaaga
      961 ggtaaacgga cggacgcact ttgccagcat gccaagaaac ttctaccaag attatactca
     1021 agactctttc agtatacagg atgggaattc tcagtattgt aattcatcag gattcatttt
     1081 cacaaaagac cagcctgtag caaccaacat gtattttgac agtgggaacc ctgccccaag
     1141 cagcgcatcc cagcaggcaa actgtcagcc agctcccgag ccccctcctt cacagatgta
     1201 ccccgagtca gtggttgccg agaaacagta ttttatcgaa aagttaacag caactatctg
     1261 gaagaaccta tccaatccag agatgacttc tggatctgat aagattaatt atacctacat
     1321 gctaactcgc tgtattcagg cctgtaagac aaatcctgag tatatatatg ctcctttaaa
     1381 agaaatccct cctgctgaca tccccaaaaa taaaaaactt ctcacggatg gttatgcgtg
     1441 tgaggttaga tgccaaaata tctatctaag tacaggttat gcaggtagca agaatgggtc
     1501 cagagatcgg gctactgagc tagctgtaaa actcttgcag aagcggatcg aggttagagt
     1561 tgtccggcgg aaattcaagc acataattgg agaggacctt gtggtgtgtc agattggtgt
     1621 gctttcctat gaatttcccc cagctctgaa accaccagaa gacctggtag tactgggaaa
     1681 ggatgcttct gggcagccta tttttaatag ttctgccaaa cactggacca attttgtcat
     1741 tacagaaaat gcaaatgatg cgattggcat ccttaacaat tctgcctcat tcaacaaaat
     1801 gtcaattgag tacaaatacg agatgatgcc aaaccgcaca tggcggtgcc gcgtattcct
     1861 gcaagatcac tgcttagctg agggttatgg aaccaagaaa acaagcaaac atgcagctgc
     1921 tgatgaggct ttgaaagttc tccaaaaaac acaacccact tattcgtctg tcaaaagttc
     1981 ccagtgccac tcgggctctt cacccaaagg ctctggaaag aagaaagata taaaagatct
     2041 tgtagtttac gagaattctt ccaatcctgt gtgcacactg aatgatacgg ctcaatttaa
     2101 ccgaatgacg gttgaatatg tctatgaaag gatgacaggt ctccgctgga aatgcaaggt
     2161 gattctcgag agtgaagtga ttgcggaagc agttggagtg aagaaaagtg tcaagtatga
     2221 agctgctgga gaagctgtaa aaaccctcaa gaagacacag ccaactgtca ttaataactt
     2281 gaagaaaggg actgttgaag atgtgatttc aaggaatgaa attcagggcc gctcagcaga
     2341 agaagcttac aaacagcaaa tcaaagaaga taacataggg aatcaactgc tgaggaagat
     2401 gggttggacg ggtggtggtt taggtaaatc tggtgagggc atacgggagc ctatctcagt
     2461 taaagagcag cataagcggg aagggcttgg tctagatgtc gagagggtca ataaaattgc
     2521 taagagggat atagaacaga tcatcagaaa ctatgcccgc tctgaaagcc actcagattt
     2581 gaccttctcc acagagctga ccaatgacga acggaagcaa atacatcaga ttgctcagaa
     2641 gtatggccta aagagtaagt ctcatggggt gggccatgat aggtacctgg tggtaggtag
     2701 aaaacggcgg aaggaagacc tactagatca actcaaacag gagggccaag tgggacatta
     2761 tgagcttgtt atgccccaag caaactaaga ttttactaaa ttaatcttat aaatgcctga
     2821 tgaggcagat atacagataa caaaaaagct acatgttccg gttgaagagt attcattctt
     2881 aagatgtttc accttgttca tttcatatag tgctttatta ggtattggaa cctggagaat
     2941 tctgtccact tgtactataa gcttaatcca gcagagatat tgtgcagcta ctgtttgtgt
     3001 ctttgatatt gctctgttcc ctcagatttt agtagtttgt acaagcaaaa acacccatct
     3061 aagtgcaatt tcaccctgag gaaaataatt cacattataa agggcatagc acagtaatct
     3121 gcaacaatct gtagtcaatg ctgagactct aactacgcta attccagatt tacttaacat
     3181 gtcaggtcat tttgtatcat cgattttcat ctttgtgaga agccagttgt agagcattta
     3241 acaataaagt gtgctgtacg tgtaaatgtc tttatcaact aaatgatgta aaactttctt
     3301 taaagtaatt ttagtgtgtg tttatttata acttctacca tgtgatttcc aggatattgg
     3361 aagtgattta ctgtatcttg tgacatgtga cttttaacaa attctagtct tcacgctgag
     3421 agagcactac ttgagagaga tgtcgaaaag tttccaaaag gtcttgattc aatcagaaga
     3481 aaggaagctt gaactgtttg ttcttggtgc cttgcagaga gactcagagc aactctccat
     3541 tgtagctttc atacggtttg tgcaccacac ccaaggcaac cagagctgtg gtagagcttg
     3601 gtaaaagacg gaagatacat tggtgctttg atgaaaaagg tcagttagct ggttcccctc
     3661 tcaaaaagct tatttctccc caaagccaac tttgtaacat acttaaaact gctattttcg
     3721 cttatttctg gaatataaaa atgtataaaa ataagagtta gtgtatgctt cctgaataaa
     3781 aaggagccag agttgatcaa aatggtggtg taattatttc tggagagcag cctggcagca
     3841 atattttgga tttttgaaag tgatggttac ataaaatatt tcagttagag cacacatgga
     3901 taaatgtaat gacttagcaa acgggagcag aatctgtcac tcgtcacggt ttttttgttt
     3961 tgtggttttt tttccttgaa tgccaatatt ctagcttatc aaatctttgg tttactttta
     4021 tgtatcttag atgagtcaac taaaatccag caatatagca aatgaatatt aatatttagt
     4081 tatctccaga aaaaaatgat ggtaaggact cttaggttgt ttgcaatgtc tttttaaaaa
     4141 atatttattt ttttataatg tgtgtatgtc tgtgtgtgta gtgtgggggc ggttatatgc
     4201 atgtgtgtgc atatgcccat ggaggccaga ggtgtcagtt ggagctggca atacaagcag
     4261 tagtgagtct cctgacactg gtgctggaaa ctgagctctg gtcctctggg atgtgttctt
     4321 aactgctgag ccagctcttg agtgcccatt tgcagtgtcc gtgtttggca gataaatggc
     4381 tcacgataca tggtaaattc ctttttgccc tccccttttc tatttaatgc taaaaagcta
     4441 gagtaaaatg agtatttaaa aatatcactt agcttttata cctggatctc ttaactttca
     4501 tgcgcctaca ttgggcagca cagtatggca tcagccttcc acttgttttg cataccatag
     4561 tctacatact tcattagttt tagtaaaaga gatgtgcatt ttattttggt gcttaatgct
     4621 ttagcaaaaa aagagaacta tgatagaatt ttgtgattat aattattttt ttacctgcaa
     4681 aattcactcc cattttggaa agttgtagtt caggtagtta gaacactgtg tccttggttg
     4741 tctgagtggc aaaaggtggt ttttagagat tacaagatgt ggaaacttgg tttgcattct
     4801 ctctttacat atcttcctcc cagaatgttt ggttgtttgg tttgggtgga aaaaatggta
     4861 ggaaatccaa agttaggttt gtttttaaaa gtgtactaaa gcagatgact tacacttaag
     4921 gctttgtgat aattgggaaa ggtttataag aattgtgttc attttagggg gccaaataac
     4981 ttggtagagc agctttagta tcaatgtgga attagaacaa agtcaccaac tgcctgagaa
     5041 taaagtaatg tggagaaatg aggttgaggg atgagctgct gtcgacttgg ctgttccagt
     5101 ttgcagtttc cccttttgtt ggtccttgca ttttcctctt ctaagagata gcagtcattt
     5161 ttagctgagg aactttgctg taaaacctga cagtatatga gcacttctaa gtttcatttg
     5221 tattaaatat aagctgaaaa ctctttatgt gcttgtgctc acagagccac tttttcatcc
     5281 ctcccacctt gattgcaaaa gtgaagagaa atacacattc cattggggcc atttctttac
     5341 ttttttaaaa atagtattca gtgtgttcgc tttgctctga gtaacccttg aaacggttcc
     5401 taaataaagg actctaatta caactttggt tcttcagcat acccttcccc acataagcag
     5461 gtgcagaatt gaaggcaaga ttgtatctca aaaaggcacc ttgcaaatct gctttagctt
     5521 tcttgtaatt acatgcaggc aaggcagcct gtgttaaaaa ttataaagga gagaaaaggg
     5581 tgatttgtac taaatgttcc aaggagtgtt tagtagtggt agctttgact atgtctatgc
     5641 cagcttcatt attaaggctg taaaaggatt atctcatcag aaattggaga tggtgtttct
     5701 cagaaagtgt acaaaataaa atgttactaa atca
//
