LOCUS       NM_001394370            2066 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus nipsnap homolog 2 (Nipsnap2), transcript variant
            1, mRNA.
ACCESSION   NM_001394370 XM_006249280
VERSION     NM_001394370.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2066)
  AUTHORS   Shanmughapriya S, Rajan S, Hoffman NE, Higgins AM, Tomar D, Nemani
            N, Hines KJ, Smith DJ, Eguchi A, Vallem S, Shaikh F, Cheung M,
            Leonard NJ, Stolakis RS, Wolfers MP, Ibetti J, Chuprun JK, Jog NR,
            Houser SR, Koch WJ, Elrod JW and Madesh M.
  TITLE     SPG7 Is an Essential and Conserved Component of the Mitochondrial
            Permeability Transition Pore
  JOURNAL   Mol Cell 60 (1), 47-62 (2015)
   PUBMED   26387735
REFERENCE   2  (bases 1 to 2066)
  AUTHORS   Brittain JM, Wang Y, Wilson SM and Khanna R.
  TITLE     Regulation of CREB signaling through L-type Ca2+ channels by
            Nipsnap-2
  JOURNAL   Channels (Austin) 6 (2), 94-102 (2012)
   PUBMED   22627147
  REMARK    GeneRIF: The experiments highlight a novel role of Nipsnap2 in
            transcriptional regulation via L-type Ca(2+) channels.
REFERENCE   3  (bases 1 to 2066)
  AUTHORS   Zhao X, Leon IR, Bak S, Mogensen M, Wrzesinski K, Hojlund K and
            Jensen ON.
  TITLE     Phosphoproteome analysis of functional mitochondria isolated from
            resting human muscle reveals extensive phosphorylation of inner
            membrane protein complexes and enzymes
  JOURNAL   Mol Cell Proteomics 10 (1), M110.000299 (2011)
   PUBMED   20833797
REFERENCE   4  (bases 1 to 2066)
  AUTHORS   Martherus RS, Sluiter W, Timmer ED, VanHerle SJ, Smeets HJ and
            Ayoubi TA.
  TITLE     Functional annotation of heart enriched mitochondrial genes GBAS
            and CHCHD10 through guilt by association
  JOURNAL   Biochem Biophys Res Commun 402 (2), 203-208 (2010)
   PUBMED   20888800
REFERENCE   5  (bases 1 to 2066)
  AUTHORS   Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl
            E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES and
            Mann M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000227.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001394370.2.
            
            On Apr 16, 2021 this sequence version replaced XM_006249280.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR8487227.315198.1,
                                           SRR8487231.101674.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN11044071
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-117               JACYVU010000227.1  8213825-8213941     c
            118-257             JACYVU010000227.1  8200336-8200475     c
            258-303             JACYVU010000227.1  8200196-8200241     c
            304-398             JACYVU010000227.1  8195080-8195174     c
            399-469             JACYVU010000227.1  8194636-8194706     c
            470-610             JACYVU010000227.1  8193227-8193367     c
            611-642             JACYVU010000227.1  8191320-8191351     c
            643-737             JACYVU010000227.1  8186484-8186578     c
            738-821             JACYVU010000227.1  8184903-8184986     c
            822-2066            JACYVU010000227.1  8181456-8182700     c
FEATURES             Location/Qualifiers
     source          1..2066
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q13"
     gene            1..2066
                     /gene="Nipsnap2"
                     /gene_synonym="Gbas"
                     /note="nipsnap homolog 2"
                     /db_xref="GeneID:498174"
                     /db_xref="RGD:1566421"
     exon            1..117
                     /gene="Nipsnap2"
                     /gene_synonym="Gbas"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..886
                     /gene="Nipsnap2"
                     /gene_synonym="Gbas"
                     /note="glioblastoma amplified sequence"
                     /codon_start=1
                     /product="protein NipSnap homolog 2"
                     /protein_id="NP_001381299.1"
                     /db_xref="GeneID:498174"
                     /db_xref="RGD:1566421"
                     /translation="MAARVLLARGGLLRPAAPGSFLPGLRRVTSSGHRAREDSWLKSL
                     FVRKVDPRKDAHSNLLAKKETSSLYKLQFHNVKPECLDAYNKICQEVLPKIHEDKQYP
                     CTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLRENQEFVSFRKARSDMLLSRK
                     NQLLLEFSFWNEPVPRSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDSNEAVGGF
                     FSQIGQLYMVHHLWAYKDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLK
                     TSPLQ"
     exon            118..257
                     /gene="Nipsnap2"
                     /gene_synonym="Gbas"
                     /inference="alignment:Splign:2.1.0"
     exon            258..303
                     /gene="Nipsnap2"
                     /gene_synonym="Gbas"
                     /inference="alignment:Splign:2.1.0"
     exon            304..398
                     /gene="Nipsnap2"
                     /gene_synonym="Gbas"
                     /inference="alignment:Splign:2.1.0"
     exon            399..469
                     /gene="Nipsnap2"
                     /gene_synonym="Gbas"
                     /inference="alignment:Splign:2.1.0"
     exon            470..610
                     /gene="Nipsnap2"
                     /gene_synonym="Gbas"
                     /inference="alignment:Splign:2.1.0"
     exon            611..642
                     /gene="Nipsnap2"
                     /gene_synonym="Gbas"
                     /inference="alignment:Splign:2.1.0"
     exon            643..737
                     /gene="Nipsnap2"
                     /gene_synonym="Gbas"
                     /inference="alignment:Splign:2.1.0"
     exon            738..821
                     /gene="Nipsnap2"
                     /gene_synonym="Gbas"
                     /inference="alignment:Splign:2.1.0"
     exon            822..2066
                     /gene="Nipsnap2"
                     /gene_synonym="Gbas"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgacaccga ggcggtagga gcttcaggct ccggagcaag atggcggcgc gggtgctgct
       61 cgcgcgagga ggcctgctgc ggccagccgc ccccggcagc ttcctgcccg ggctccggag
      121 agtgacgtcc tcgggtcacc gagctcggga agacagctgg ctaaagtcct tatttgtcag
      181 aaaggtcgat ccgagaaaag acgcccactc caacctccta gccaaaaagg agacaagcag
      241 tctgtacaag ttacagtttc acaacgttaa gccggaatgc ctagatgctt acaacaaaat
      301 ttgtcaagaa gtgttaccaa agatccatga agacaagcag tacccttgca ccttggtggg
      361 cacgtggaac acgtggtacg gcgagcagga tcaagccgtc cacctctgga ggtatgaggg
      421 aggctatcca gccctcacgg aggtcatgaa taaactcaga gaaaaccagg aatttgtaag
      481 tttccgtaag gccagaagcg acatgcttct ctccaggaag aatcagctgc tgttggagtt
      541 cagtttctgg aatgagccgg tgccgagatc aggccccaat atatacgaac tcaggtccta
      601 ccaactccga ccaggaacga tgatcgaatg gggcaattac tgggcccgtg ccatccgctt
      661 tagacaagac agtaatgagg cagtcggggg attcttctct caaattgggc agctatatat
      721 ggtgcatcat ctttgggctt ataaagatct tcagaccagg gaggacatac ggaacgcagc
      781 ctggcacaaa catggctggg aggaacttgt gtactatacg gtcccactca tccaggaaat
      841 ggagtccagg atcatgatcc cgctcaagac ctccccgctc cagtgacgct tccgtgtgcc
      901 tacgcagatt cccgtgatga atgtgtgtca tgatttcatc tcacccagtc atcgagtgga
      961 aagcaagccg aggtgtaaac tgctgtacat agcttgtaag atgtcttttc tttaaaattt
     1021 aataatcatg caatggaaac tcaggagggt tggactcaca gaagcggcgc cgtctctgct
     1081 caccaaacgc tccttagcct ccggcccttc aggaaaacag gatcttttga ggccgggtgt
     1141 ggtagtttag cactcaggga gcagaggcag gagaattaca gtaagtccta ggccaatctg
     1201 gcctacttac agagtttcag accagcttgg accttgtgag accctgtctg aataaccaaa
     1261 attaaagtcc gaattctctc agagtaaaat cccagctatg aaaaggaatc agctattatc
     1321 tcttgctatt aaaaaaaaaa aatctgtttc acgattacag atttttacaa atttccttcc
     1381 ttcaggaaga aatacaaatg aaatcatgtt tcctgagcaa tttttcttga gtctcaaacg
     1441 aggaacaaat tctgggtgta cccaatggct gcgaatgcta tgattttgtg attttttttt
     1501 tttttttttt tttttttttt tggtcagtgg gtcagcaggc cggaagggtg gccaccgtgc
     1561 acctagccag ccatgcagcc tccctccacc aggcactgcg tgccaagagg ttggcatgaa
     1621 gccctgcgcc acatgtgatt ttgaataaac acctcaacta gcactaattt tatttgcaat
     1681 atttttctat aaaacacgta gctcttggaa aagaggtttt attttccaag ccaccgtttc
     1741 tgacctccaa cctctggttc tattttggta agctcccagc agacacttcc aagatctcgt
     1801 accaagggca gtgcacactg ggtctaagtt ggcataaagc ttcatattct gtccgtctct
     1861 gtttggtttt gttttttaat agagcgtgcc aattttgtga ctgtaatcat gtgaaagccc
     1921 cactgaaccg aagaattgtg tctgccctac aaattgatct gtgtaaaata aaatataact
     1981 aaatctccta tcagatgtct aatttttaca ggcaaatggt tttctccaag aacatattaa
     2041 ataaaatcct cttaattttc acgttt
//
