LOCUS       NM_001401452            4135 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus NIPA-like domain containing 1 (Nipal1), mRNA.
ACCESSION   NM_001401452 XM_006250895
VERSION     NM_001401452.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4135)
  AUTHORS   Goytain,A., Hines,R.M. and Quamme,G.A.
  TITLE     Functional characterization of NIPA2, a selective Mg2+ transporter
  JOURNAL   Am J Physiol Cell Physiol 295 (4), C944-C953 (2008)
   PUBMED   18667602
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            On Feb 11, 2022 this sequence version replaced XM_006250895.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.54491.1,
                                           SRR26643294.49941.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-142               JAXUCZ010000014.1  35915517-35915658   c
            143-409             JAXUCZ010000014.1  35903662-35903928   c
            410-466             JAXUCZ010000014.1  35901673-35901729   c
            467-557             JAXUCZ010000014.1  35898639-35898729   c
            558-718             JAXUCZ010000014.1  35895720-35895880   c
            719-4135            JAXUCZ010000014.1  35891647-35895063   c
FEATURES             Location/Qualifiers
     source          1..4135
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p11"
     gene            1..4135
                     /gene="Nipal1"
                     /gene_synonym="Npal1; RGD1310092"
                     /note="NIPA-like domain containing 1"
                     /db_xref="GeneID:289594"
                     /db_xref="RGD:1310092"
     exon            1..142
                     /gene="Nipal1"
                     /gene_synonym="Npal1; RGD1310092"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..1347
                     /gene="Nipal1"
                     /gene_synonym="Npal1; RGD1310092"
                     /codon_start=1
                     /product="magnesium transporter NIPA3"
                     /protein_id="NP_001388381.1"
                     /db_xref="GeneID:289594"
                     /db_xref="RGD:1310092"
                     /translation="MGAQLRLPPGEPCREGYVLSLVCSNSSQALCEITNVSQPLAYPV
                     LYTNPNSSTSNFSISAGVENKYSLYVGLVLAISSSFFIGSSFILKKKGLLQLADKGIT
                     RAGQGGHSYLKEWLWWAGLLSMGAGEAANFAAYAFAPATLVTPLGALSVLISAILSSY
                     FLNEHLNIHGKIGCILSILGSTVMVIHAPQEGEVTSLHEMEMKLRDPGFISFAVIVSV
                     ISLVLILVVAPRKGQTNILVYISICSLIGAFSVSSVKGLGIAIKELLERKPVYKDPLV
                     FILLAVLTLSVTTQINYLNKALDTFNTSLVTPIYYVFFTSMVVTCSAILFQEWYGMRA
                     GDIIGTLSGFFTIINGIFLLHAFKNTNITWSELTSTAKKEVLSSNGSQNSYVLLENAD
                     CSTSGCDDDITLFSRTGDQSIHKL"
     exon            143..409
                     /gene="Nipal1"
                     /gene_synonym="Npal1; RGD1310092"
                     /inference="alignment:Splign:2.1.0"
     exon            410..466
                     /gene="Nipal1"
                     /gene_synonym="Npal1; RGD1310092"
                     /inference="alignment:Splign:2.1.0"
     exon            467..557
                     /gene="Nipal1"
                     /gene_synonym="Npal1; RGD1310092"
                     /inference="alignment:Splign:2.1.0"
     exon            558..718
                     /gene="Nipal1"
                     /gene_synonym="Npal1; RGD1310092"
                     /inference="alignment:Splign:2.1.0"
     exon            719..4135
                     /gene="Nipal1"
                     /gene_synonym="Npal1; RGD1310092"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctccactg ctcctccgga acctacgctg gtcccgggac actgactggt ttgtgagaaa
       61 ctattgctag cacggagaaa gcccggtccc caggccatgg gggcacagct gaggctgcca
      121 cccggagagc cctgccgcga agggtatgtg ctgtctctgg tctgctcaaa ctcttcccag
      181 gctctgtgtg agatcacaaa cgtgtcacag ccgctggctt atcctgtcct ctacacgaac
      241 ccgaattcct ccacaagcaa cttcagcatc tcagcaggtg tagaaaacaa atatagtctg
      301 tatgtgggct tggtattggc cataagctcc agctttttta ttggctcaag tttcatactc
      361 aaaaagaagg gtctcttgca actggccgac aagggcatta ccagagcagg gcaaggtgga
      421 cattcttacc tcaaggaatg gctgtggtgg gcgggactgc tgtcgatggg agctggagag
      481 gctgcaaact tcgccgctta tgcctttgca cctgccacct tggtcacccc tctgggggct
      541 ctgagcgttc tcataagtgc aatattatct tcctattttt taaatgagca cttgaacatt
      601 catgggaaaa taggctgcat actaagcata ttggggtcaa ctgtgatggt tatccacgcc
      661 ccgcaagagg gagaagtcac gtctttgcat gaaatggaaa tgaaactgag agatccaggg
      721 ttcatttcct ttgctgtgat cgtctctgtg atctcactgg tgctgatttt ggttgtggcc
      781 ccgaggaaag gccagactaa tatattggtc tatatctcaa tctgttcttt gattggagcg
      841 ttttccgttt cttccgtgaa aggcttgggg attgccatta aggaactgct ggaacggaag
      901 cctgtttaca aggatcccct ggtcttcatc ctgttggccg tgcttacact ttcagtgacg
      961 acccagatta actatctcaa caaggccctg gacactttca acacgtctct ggtgactccc
     1021 atttactatg tgttcttcac atccatggtg gtgacatgtt ccgccatctt gttccaggag
     1081 tggtatggca tgagagctgg ggatatcatc ggcaccctga gcgggttctt caccatcatc
     1141 aatggcatct tccttctaca tgcttttaaa aacaccaaca tcacctggag cgagctcacg
     1201 tctacggcta agaaagaagt cctttcttca aatggcagtc agaacagtta tgttttacta
     1261 gagaatgcag actgctcaac ctctgggtgt gatgacgaca tcaccctgtt tagcaggact
     1321 ggtgaccaaa gtatccataa actttgaacc tcaaccaaga cacccgaaga gaaacaatac
     1381 ttattcttgg aaggtctgtt ggtatgttag catgtgtaac actgtacaag tcctctggat
     1441 gggaggccaa gcaaaaagcc tttgctctgc agagcctcca aattggaaaa tcaagtttaa
     1501 tcttcttcta gaggattcct gtcttttaag ttttcaaaac cactgaaaca gtccccaagt
     1561 gccacagaag tcaaaggtgt acgtttgtct cagaataagt cttcgggcca gtagatttgg
     1621 ccctgccagg gggtgcctcc tctcttcctc cctgcctgct cttggactca gggtgactca
     1681 cagatctgct aactgtgctc tgagtgagca gagtctcgga cgccattgcc caatgagtca
     1741 taagctcaag ctattgaaac taagaaacgg gacactggtg tattgacctc tggcctgcag
     1801 tgccttcttt ctaaagtaca cagcagacag gcaaaatgtt aaggaacata ctggactaaa
     1861 atgtttctgg aatgtatttt tctttctttt tcccaaacac acatatacaa ttatgtcaga
     1921 gaatctatta acacagacct ggatactgta ggcaaaacat attttctgga aatcccaagt
     1981 gaatttagct ttgcaatgac ttacaacagt cattttgttc cgttttctgt tttcttttct
     2041 ttcttggttc tttcagacat gttcttgcta tatgacccag gccggcctcc agttcagcac
     2101 tcctttgcgt ctgtctccta agtgcctggg ttaaaggttt gtaccaccat gccaacttct
     2161 ttctgaaaaa ctactatttc gtagatttct tcttgttgac atagaggttt cgtgaaagca
     2221 gtcactatac aatgtgaagt tcatagcgtg cttccgtttc ctcagaggtc ttatccttaa
     2281 aaggtgggtc atccaaaacc gaggacagct aacagattcc ttgcacaatc ttaatgttct
     2341 tttaaaattt accattttca ccttaataag gaaattataa acagtttaac tttccagaat
     2401 gggcacggcc tactgttgtg ttcagtaact gatgcctttt tttttttctt ttatccaact
     2461 gaattcctca tgaccacact ttccaattca gatcattgat aagtgtattt gtagaaattc
     2521 cttttaagaa gagtcctgag acatgctaca ggaagtatgt tttgctcatt aaaattttgc
     2581 atttgatttc tctgactcat tctagacctg tgctcttgga atcttcagcg agagtagcgg
     2641 ttgagtgcag ttaactgcac tgtgtgtttg ggaagctgat aatccgtggg catcccatga
     2701 attgatacct caaggcaaat acatgtttac tctctgtcac tgactccctt tgggtagcag
     2761 acgtagaagc tgtgagcaca cgtttgtaga aaattatctt ctgaaaggat agtgtgtttg
     2821 aaacctgtac aaattctttt gccagttttc ctttatgctt tgacaactcc actgagttcc
     2881 ccagggtatt ttcttggtga ggacctcagt cctctccctt gacatctttc ctcaggttgt
     2941 gcccattctc cattctagtg atcttaactt tgagacactt agtaaatgtc atttgttact
     3001 tgacacctta gctgtcaagt tttccccttg gtacattgtt cataggtcaa agattcctgg
     3061 aacacaagaa ccgatgtgtc ctggtttgga gaatgagctg ggttaacata cacccccagg
     3121 agaaagactg agagatttca tcagttgtca tatgtggaga agcaataaac aattggcaaa
     3181 cattttcaaa tctctggaaa gattgctgtt agtacacatt taaaaaatta agacattact
     3241 gtagatctaa taccacgact gaatcttggg ttggaagata ctaatggagg aagagtaaac
     3301 tactgtgtcc ctctatgaca ttccgaactg ctctcttact catgcgcatt tgaatgtgta
     3361 tccttgtcat cacagagaca tgagttattt ggtggatatc aacgtgtgtg taaagaaact
     3421 ggttttgcct tttgaattgt aacttcacca ttaggtcaat gattaatgat tctatttttc
     3481 atccagagta aaaggtaatc ataaaattga aacattggat taaattaaca cttctttttt
     3541 taaaaaaagg aagaaaatac taatccacat acatcgaaag cttcttatgt tgtgcccagt
     3601 aagccatagg cacttcatta gagatgattc tcattgaact ggaattctaa tcctccttct
     3661 tactagagag aggaggacct cagaggacaa gtttgtgtga attaattctt catcgctcct
     3721 actgaggatt attcattctt agacagtcca agtgaaggtg aattcatcat tgtccactct
     3781 acatcacaat acagaaccat tccaacaaaa atattttccc cagagagggg gaatgtagct
     3841 cagtgctctg ctgacatagc tgatgtgggc acagacactg gctttgctct tcaacatgag
     3901 ggggcaaatt ataaaaccag tggaaccaaa ctaagtgtca ccttcacctt tgaaagcttt
     3961 ggatgaatgg cagggggagg gggaatcata tgaatatgtt gaatgttctc aaatattttt
     4021 gataaactgt gttcatgaga gttatatttt tcaactgttt ataaatacta ttcattttag
     4081 tttgtacatt tgtaatgcct cggtatattt ccaataaaat aatattgttt tattg
//
