LOCUS       NM_021595                891 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ninjurin 2 (Ninj2), mRNA.
ACCESSION   NM_021595
VERSION     NM_021595.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 891)
  AUTHORS   Guo,H.M., Zhang,Y., Zhang,Y., Jiao,P.F., Fan,X.C., Kong,C.L.,
            Wang,T., Li,X.X., Zhang,H.W., Zhang,L.R., Ma,M.Y. and Bu,H.L.
  TITLE     Spinal Ninjurin2 contributes to the neuropathic pain via
            NF-kappaB-mediated neuroinflammation in the spared sciatic nerve
            injury rats
  JOURNAL   Int Immunopharmacol 99, 107918 (2021)
   PUBMED   34320458
  REMARK    GeneRIF: Spinal Ninjurin2 contributes to the neuropathic pain via
            NF-kappaB-mediated neuroinflammation in the spared sciatic nerve
            injury rats.
REFERENCE   2  (bases 1 to 891)
  AUTHORS   Araki,T. and Milbrandt,J.
  TITLE     Ninjurin2, a novel homophilic adhesion molecule, is expressed in
            mature sensory and enteric neurons and promotes neurite outgrowth
  JOURNAL   J Neurosci 20 (1), 187-195 (2000)
   PUBMED   10627596
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Mar 26, 2021 this sequence version replaced NM_021595.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF250322.1, AB040815.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-162               JAXUCZ010000004.1  154978801-154978962
            163-397             JAXUCZ010000004.1  155078496-155078730
            398-582             JAXUCZ010000004.1  155079248-155079432
            583-891             JAXUCZ010000004.1  155080552-155080860
FEATURES             Location/Qualifiers
     source          1..891
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..891
                     /gene="Ninj2"
                     /note="ninjurin 2"
                     /db_xref="GeneID:59115"
                     /db_xref="RGD:620552"
     exon            1..162
                     /gene="Ninj2"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..564
                     /gene="Ninj2"
                     /note="nerve injury-induced protein 2"
                     /codon_start=1
                     /product="ninjurin-2"
                     /protein_id="NP_067606.1"
                     /db_xref="GeneID:59115"
                     /db_xref="RGD:620552"
                     /translation="MESDREIIHLQHRHSTPGGNQRHINLNHYATKKSVAESMLDVAL
                     FMSNAMRLKSVLEQGPFSQYYTTLLTLISASLLLQVVIGILLVVIARLNLNEVENQWR
                     LNQLNNAATTLVFITVVINIFITAFGAHKTGSVAARTSSNPI"
     exon            163..397
                     /gene="Ninj2"
                     /inference="alignment:Splign:2.1.0"
     exon            398..582
                     /gene="Ninj2"
                     /inference="alignment:Splign:2.1.0"
     exon            583..891
                     /gene="Ninj2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaatagctgg tctgtcttgc agcagcgctg tctcccacct cagaagagct ggaagcacag
       61 actgccctgc taagagccca cgcaaactac aggcactcgg cgggtggcaa gtggcccaag
      121 gacagcaaga tggagtcaga ccgagaaatc atccaccttc aacacaggca ctccacaccc
      181 ggagggaacc agaggcacat caacctgaac cattatgcca ccaagaagag tgtggcagag
      241 agcatgctgg atgtggctct ctttatgtcc aatgccatgc ggctgaaatc agtcctggag
      301 caagggccat tctcgcagta ctacaccacc ctcctcaccc tcatcagcgc ctccctgctc
      361 ctgcaagtgg tcattggcat ccttcttgtg gtcatcgcca ggctgaacct gaatgaggta
      421 gaaaaccagt ggcgtttaaa ccagctcaac aatgctgcca ccaccttggt cttcataact
      481 gtggtcatca acatttttat cactgctttt ggggcacaca agacaggttc cgtggctgcc
      541 aggacctcca gcaatcctat ttaatgtcca cctaggtccc aggagctggg tctaaagcca
      601 cttcagcctt tgtttctgac ctgtcaggct aactagcact tccaacagcc tcctggagag
      661 cttcggggac aatggagatg cccctgcctc tcacccacag caccagagtt aaggttcgcc
      721 cctttactgg gtgacataat tgcatcttgg tctggaggcc tgagcttctt ccaccaacag
      781 taactccgtc tgctgaggca gcatccgggc actctggttg cactgcactc cttccctcca
      841 tattcccttt ctgcaaaatg gaatctatct ataaaggtat ctgaaaatcc a
//
