LOCUS       NM_001033900            1349 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Rattus norvegicus neugrin, neurite outgrowth associated (Ngrn),
            transcript variant 2, mRNA.
ACCESSION   NM_001033900 XM_218821
VERSION     NM_001033900.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1349)
  AUTHORS   Arroyo,J.D., Jourdain,A.A., Calvo,S.E., Ballarano,C.A.,
            Doench,J.G., Root,D.E. and Mootha,V.K.
  TITLE     A Genome-wide CRISPR Death Screen Identifies Genes Essential for
            Oxidative Phosphorylation
  JOURNAL   Cell Metab 24 (6), 875-885 (2016)
   PUBMED   27667664
REFERENCE   2  (bases 1 to 1349)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 1349)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 1349)
  AUTHORS   Ishigaki,S., Niwa,J., Yoshihara,T., Mitsuma,N., Doyu,M. and
            Sobue,G.
  TITLE     Two novel genes, human neugrin and mouse m-neugrin, are upregulated
            with neuronal differentiation in neuroblastoma cells
  JOURNAL   Biochem Biophys Res Commun 279 (2), 526-533 (2000)
   PUBMED   11118320
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM062823.1, BC101926.1 and AA818112.1.
            
            On Jul 16, 2009 this sequence version replaced NM_001033900.1.
            
            Transcript Variant: This variant (2) encodes the functional
            protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM062823.1, FQ215222.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                FM062823.1         1-26
            27-1322             BC101926.1         1-1296
            1323-1349           AA818112.1         1-27                c
FEATURES             Location/Qualifiers
     source          1..1349
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..1349
                     /gene="Ngrn"
                     /gene_synonym="Neugrin"
                     /note="neugrin, neurite outgrowth associated"
                     /db_xref="GeneID:499191"
                     /db_xref="RGD:1583734"
     exon            1..215
                     /gene="Ngrn"
                     /gene_synonym="Neugrin"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..933
                     /gene="Ngrn"
                     /gene_synonym="Neugrin"
                     /note="neurite outgrowth-associated protein; mesenchymal
                     stem cell protein DSC92"
                     /codon_start=1
                     /product="neugrin precursor"
                     /protein_id="NP_001029072.2"
                     /db_xref="GeneID:499191"
                     /db_xref="RGD:1583734"
                     /translation="MALSLSLFLGGRVRAAVARCGFASQGVAGPGSISREPDPDSDWE
                     PEERELQEVESALKRQKKAMRFQKIRRQMEAPGAPPRTLTWEAMEQIRYLHKEFAESW
                     SVPRLAEGFDVSTDVIRRVLKSKFIPTLEQKLKQDQKVLKKAGITRVVWQLPVSEDTL
                     KPLSAGHPMSGPLLMPGDEVSSNSQTHSRALKVKSNAPSAEAQKKREEKNKRIRVLAE
                     SLVPTTTALGHQRELQKYTTHDSEADRRANNHILPSVEKLEELEAGEPGDQNFSSKVV
                     QKGREFFDSNGNFLYRI"
     exon            216..326
                     /gene="Ngrn"
                     /gene_synonym="Neugrin"
                     /inference="alignment:Splign:2.1.0"
     exon            327..1332
                     /gene="Ngrn"
                     /gene_synonym="Neugrin"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgcttccggt gctctccggt cgcgagctgt agatcacctc ctcgcatcgc aatggcgctg
       61 tctctgagcc ttttcttggg cggtcgtgtc cgcgctgctg tcgctcgctg tgggtttgcg
      121 tcccagggcg tggcgggtcc gggttctatc agccgcgagc cagatcccga ttccgactgg
      181 gagccggagg agcgggaact ccaggaagtg gagagcgctt tgaaacgaca gaaaaaagca
      241 atgcgattcc agaaaattcg aaggcaaatg gaggctccag gtgccccacc tagaacactg
      301 acatgggaag ccatggaaca gatccggtat ttacataagg aatttgcaga gtcctggtca
      361 gttcccaggt tggcagaagg ctttgatgtc agcactgatg ttatccgaag ggttttaaaa
      421 agtaagttta tacccacttt agagcagaaa ctgaagcagg accaaaaggt cttgaaaaaa
      481 gcggggatta cccgagtggt ttggcagctc cctgtttctg aagatacgtt gaagccgctc
      541 agtgcaggcc atcctatgtc tggccctctg ctgatgccag gggatgaagt ctcctctaac
      601 agtcagactc acagcagagc tttgaaagta aagtcaaacg ctcccagcgc agaggcacag
      661 aagaaacggg aagaaaagaa taaaagaatc cgagtcttgg cagaaagcct ggtgcctacc
      721 accacagcct tgggtcatca gagagagctt cagaaataca ccacccatga ctctgaggct
      781 gacaggagag ccaacaatca tatattacca agtgtggaga agctggaaga gttggaggct
      841 ggggagccag gtgaccagaa cttcagcagc aaagtagtac agaaggggcg tgagttcttt
      901 gacagtaacg gaaacttcct ctacagaatt tgagcctggg cctggatttt ggaaatgcct
      961 agacacagct ggacaagtag atttgaagct gccagcatcg ggcagccatt ggccactttg
     1021 gagtaagagt cgatgaggcc aggatgaggg tggatggctt acttataggt aggtcagact
     1081 tcctggagta agccccatgg atccctgtgg atctaaggac tcattcatct ttgttccttg
     1141 gaggtctttc tgttgagaac aagaattcta ggtatcctgt catggatttt tgtgataccg
     1201 tgttgggagg aagttgaaag cttgctcttg acctcttttc ctttctaatt cctgaacact
     1261 attcttgctc tgtctaatca gttggtttcc ttatgtgcag aataaagtaa aatggtgcgg
     1321 tttgatgctt ggaaaaaaaa aaaaaaaaa
//
