LOCUS       NM_031553               2569 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus nuclear transcription factor Y subunit beta
            (Nfyb), mRNA.
ACCESSION   NM_031553
VERSION     NM_031553.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2569)
  AUTHORS   Muller,P.A. and Vousden,K.H.
  TITLE     p53 mutations in cancer
  JOURNAL   Nat Cell Biol 15 (1), 2-8 (2013)
   PUBMED   23263379
  REMARK    Review article
REFERENCE   2  (bases 1 to 2569)
  AUTHORS   Freed-Pastor,W.A. and Prives,C.
  TITLE     Mutant p53: one name, many proteins
  JOURNAL   Genes Dev 26 (12), 1268-1286 (2012)
   PUBMED   22713868
  REMARK    Review article
REFERENCE   3  (bases 1 to 2569)
  AUTHORS   Tarantino,C., Paolella,G., Cozzuto,L., Minopoli,G., Pastore,L.,
            Parisi,S. and Russo,T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   4  (bases 1 to 2569)
  AUTHORS   Chang,M., Jin,W. and Sun,S.C.
  TITLE     Peli1 facilitates TRIF-dependent Toll-like receptor signaling and
            proinflammatory cytokine production
  JOURNAL   Nat Immunol 10 (10), 1089-1095 (2009)
   PUBMED   19734906
REFERENCE   5  (bases 1 to 2569)
  AUTHORS   Stros,M., Polanska,E., Struncova,S. and Pospisilova,S.
  TITLE     HMGB1 and HMGB2 proteins up-regulate cellular expression of human
            topoisomerase IIalpha
  JOURNAL   Nucleic Acids Res 37 (7), 2070-2086 (2009)
   PUBMED   19223331
REFERENCE   6  (bases 1 to 2569)
  AUTHORS   Niimi,T., Hayashi,Y., Futaki,S. and Sekiguchi,K.
  TITLE     SOX7 and SOX17 regulate the parietal endoderm-specific enhancer
            activity of mouse laminin alpha1 gene
  JOURNAL   J Biol Chem 279 (36), 38055-38061 (2004)
   PUBMED   15220343
REFERENCE   7  (bases 1 to 2569)
  AUTHORS   Haze,K., Okada,T., Yoshida,H., Yanagi,H., Yura,T., Negishi,M. and
            Mori,K.
  TITLE     Identification of the G13 (cAMP-response-element-binding
            protein-related protein) gene product related to activating
            transcription factor 6 as a transcriptional activator of the
            mammalian unfolded protein response
  JOURNAL   Biochem J 355 (Pt 1), 19-28 (2001)
   PUBMED   11256944
REFERENCE   8  (bases 1 to 2569)
  AUTHORS   Sinha,S., Maity,S.N., Lu,J. and de Crombrugghe,B.
  TITLE     Recombinant rat CBF-C, the third subunit of CBF/NFY, allows
            formation of a protein-DNA complex with CBF-A and CBF-B and with
            yeast HAP2 and HAP3
  JOURNAL   Proc Natl Acad Sci U S A 92 (5), 1624-1628 (1995)
   PUBMED   7878029
REFERENCE   9  (bases 1 to 2569)
  AUTHORS   Vuorio,T., Maity,S.N. and de Crombrugghe,B.
  TITLE     Purification and molecular cloning of the 'A' chain of a rat
            heteromeric CCAAT-binding protein. Sequence identity with the yeast
            HAP3 transcription factor
  JOURNAL   J Biol Chem 265 (36), 22480-22486 (1990)
   PUBMED   2266139
REFERENCE   10 (bases 1 to 2569)
  AUTHORS   Hooft van Huijsduijnen,R., Li,X.Y., Black,D., Matthes,H.,
            Benoist,C. and Mathis,D.
  TITLE     Co-evolution from yeast to mouse: cDNA cloning of the two NF-Y
            (CP-1/CBF) subunits
  JOURNAL   EMBO J 9 (10), 3119-3127 (1990)
   PUBMED   1698608
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC089791.1.
            
            On Feb 13, 2005 this sequence version replaced NM_031553.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089791.1, CO561802.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2569
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..2569
                     /gene="Nfyb"
                     /gene_synonym="CBF-B; CBFB; Nfya"
                     /note="nuclear transcription factor Y subunit beta"
                     /db_xref="GeneID:25336"
                     /db_xref="RGD:3172"
     exon            1..133
                     /gene="Nfyb"
                     /gene_synonym="CBF-B; CBFB; Nfya"
                     /inference="alignment:Splign:2.1.0"
     exon            134..219
                     /gene="Nfyb"
                     /gene_synonym="CBF-B; CBFB; Nfya"
                     /inference="alignment:Splign:2.1.0"
     CDS             214..837
                     /gene="Nfyb"
                     /gene_synonym="CBF-B; CBFB; Nfya"
                     /note="CBF-A; NF-YB; nuclear transcription factor Y
                     subunit B; CCAAT-binding transcription factor subunit A;
                     CAAT box DNA-binding protein subunit B; nuclear
                     transcription factor - Y beta; CCAAT binding transcription
                     factor of CBF-B/NFY-B; CCAAT-binding transcription factor
                     subunit B; nuclear transcription factor-Y beta"
                     /codon_start=1
                     /product="nuclear transcription factor Y subunit beta"
                     /protein_id="NP_113741.1"
                     /db_xref="GeneID:25336"
                     /db_xref="RGD:3172"
                     /translation="MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHED
                     TNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEAS
                     ERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVSATDG
                     LSEELTEEAFTNQLPAGLITADGQQQNVMVYTTSYQQISGVQQIQFS"
     exon            220..313
                     /gene="Nfyb"
                     /gene_synonym="CBF-B; CBFB; Nfya"
                     /inference="alignment:Splign:2.1.0"
     exon            314..444
                     /gene="Nfyb"
                     /gene_synonym="CBF-B; CBFB; Nfya"
                     /inference="alignment:Splign:2.1.0"
     exon            445..642
                     /gene="Nfyb"
                     /gene_synonym="CBF-B; CBFB; Nfya"
                     /inference="alignment:Splign:2.1.0"
     exon            643..724
                     /gene="Nfyb"
                     /gene_synonym="CBF-B; CBFB; Nfya"
                     /inference="alignment:Splign:2.1.0"
     exon            725..804
                     /gene="Nfyb"
                     /gene_synonym="CBF-B; CBFB; Nfya"
                     /inference="alignment:Splign:2.1.0"
     exon            805..2541
                     /gene="Nfyb"
                     /gene_synonym="CBF-B; CBFB; Nfya"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggcccgcgg cggagggagg ggaggccgag tcctggaagt ggagctccgc gctgggactg
       61 gttccttcgc agccattttc tgtccaacca aacagccgat tggagacggg agccaaccag
      121 ggctgcattg gaggttaaaa ttggacaaag atccaccacc tttaggacag gtgttcaaga
      181 accctgcaga taacacaatt ctgacagtat ttcatgacaa tggatggcga cagctctaca
      241 acagatgctt ctcaactagg gatttctgca gactacatcg gaggaagtca ttatgtgatc
      301 cagccccacg atgatactga ggacagcatg aatgatcatg aagatacaaa tggttcaaaa
      361 gaaagtttca gagaacaaga tatttatctt cccattgcaa atgtggctag gataatgaaa
      421 aatgccatac ctcaaacagg aaagattgca aaggatgcca aagaatgcgt tcaggagtgt
      481 gtgagtgagt ttataagctt cataacatct gaagcaagtg agcgctgtca ccaggagaag
      541 cggaagacca tcaacgggga ggacattctg ttcgccatgt ccactctcgg cttcgacagc
      601 tacgtggagc ctctgaaact gtacctccag aagttcagag aggccatgaa gggagagaag
      661 ggcattggtg gggccgtgtc tgctacagat ggactcagcg aggagctcac ggaagaggca
      721 ttcactaacc agttaccggc tgggttaata actgcagatg gccaacaaca aaacgttatg
      781 gtttacacga cgtcctatca acagatttct ggtgtccagc agattcagtt ttcatgatat
      841 gaaggaagga tggagccggg ctgtgtggag agcgcgagcg agagtctgac ggagtctgga
      901 gcagaggcat tgggaggaag tgagagtgag gccgcctcct tgtataataa gtagctgtaa
      961 cgtagcttcc tgatgcctga ctaattgagg tgttaattct gacttgagaa tctttttcat
     1021 gaatgatttt aaaagaaaaa aattggattt taaaggtatt aaaaatattt ttgttttgta
     1081 cgagagtgtg ttgctctgtg acgcctgtat gcattgtata ttgcgattta ttactgtcag
     1141 agatttgtag acagtttctt attttcatat tgaatcatgt tattttgtaa ttcaagtaag
     1201 cagctgggtt aattcataat gtttattacc cttttaataa aatataaggg tagagttcat
     1261 tttgaatgaa agttgccttt attacgaatt tgcgtttgtc ttagctatac actatcctgc
     1321 atggtaactt agccgaatgt ttagcattta tttattgaaa acattttttt tttttttttg
     1381 gtaaacagtc atagcttaag caacgtcatt tttttaactg aataattaag ttggatgcag
     1441 aagcaagtgt tgcctggcct gtcagacctg gtgcctgttg ctgtctgtgc tgttgaggca
     1501 gcttccgtta ctgccatgcc tgtgagaatt cctttccctt ccatacggtc ctgccacctc
     1561 tgaaatggcc cctttcttct tcaagtatca cagtcccctt cctgaagagg gagttttcag
     1621 tccactgata gtcatttccc ttcatggaaa ggtcaggtcc ctgtcgggct gtgggagccg
     1681 agcagtgggc gtggttctgt gcagatgctg caggtgagag caagtgagcg gaggagcggt
     1741 gaggcagggg agcagccagc acttggaatc aggagacacg gagccttttg gtgtgctgtc
     1801 acaccatctg cagtaagcta gcattagttg atgtagcgtg gtttcttttt taaagtgaag
     1861 atttctattt tctcatctag tctttttagt aatacttcct ttgaattttt gtgtatgtag
     1921 tgtggtagtt ttagccctat caaaaatggc ttattgtata gtttgtccag aggaaatttt
     1981 ggggctccag tggacaaaag caagcagttc cctaggtcca ggctgatcag taatggccac
     2041 ttgccaagag tcttgtggaa cacagctagc tactctgaga ttaaataatt cccccttctc
     2101 cttcctcctt tccttttcag tagtcacctt ctgtgtagga gatgcacata gggaagaacg
     2161 ggaggtgacg gtcaagcaga accagcagtc gtcctactgt gctgaagtaa caatgttaat
     2221 attttgataa ctcatttgtc cttttacttt gctaaatatg tatattttta taaagatggg
     2281 ctcgtgttgt gcacactgtt ttgtaactcg tttttcactt aatacattgt gaacatcttt
     2341 cccaggtcat gcatgatctt ctgcatcatt tttactgggt ttttattctg ttatatgact
     2401 gaatcatgat taatttattt aattgcctat tgcacagttt gacctttttc catctcttca
     2461 tagttataaa catagttata taagttcact gaatcttgtg tacatcgtaa cttttcttga
     2521 aataaattct tagaagtaga aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
