LOCUS       NM_001108133            5179 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus nuclear factor related to kappa B binding protein
            (Nfrkb), mRNA.
ACCESSION   NM_001108133 XM_001056399 XM_236009
VERSION     NM_001108133.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5179)
  AUTHORS   Chen,L., Cai,Y., Jin,J., Florens,L., Swanson,S.K., Washburn,M.P.,
            Conaway,J.W. and Conaway,R.C.
  TITLE     Subunit organization of the human INO80 chromatin remodeling
            complex: an evolutionarily conserved core complex catalyzes
            ATP-dependent nucleosome remodeling
  JOURNAL   J Biol Chem 286 (13), 11283-11289 (2011)
   PUBMED   21303910
REFERENCE   2  (bases 1 to 5179)
  AUTHORS   Watanabe,S. and Peterson,C.L.
  TITLE     The INO80 family of chromatin-remodeling enzymes: regulators of
            histone variant dynamics
  JOURNAL   Cold Spring Harb Symp Quant Biol 75, 35-42 (2010)
   PUBMED   21502417
  REMARK    Review article
REFERENCE   3  (bases 1 to 5179)
  AUTHORS   Yao,T., Song,L., Jin,J., Cai,Y., Takahashi,H., Swanson,S.K.,
            Washburn,M.P., Florens,L., Conaway,R.C., Cohen,R.E. and
            Conaway,J.W.
  TITLE     Distinct modes of regulation of the Uch37 deubiquitinating enzyme
            in the proteasome and in the Ino80 chromatin-remodeling complex
  JOURNAL   Mol Cell 31 (6), 909-917 (2008)
   PUBMED   18922472
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474007.2.
            
            [WARNING] On Mar 13, 2025 this sequence was replaced by
            NM_001108133.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001056399.1, XM_236009.4.
FEATURES             Location/Qualifiers
     source          1..5179
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..5179
                     /gene="Nfrkb"
                     /note="nuclear factor related to kappa B binding protein"
                     /db_xref="GeneID:315523"
                     /db_xref="RGD:1310558"
     exon            1..113
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            114..269
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..4025
                     /gene="Nfrkb"
                     /codon_start=1
                     /product="nuclear factor related to kappa-B-binding
                     protein"
                     /protein_id="NP_001101603.1"
                     /db_xref="GeneID:315523"
                     /db_xref="RGD:1310558"
                     /translation="MDSLDHMLTDPLELGPCGDGHSTGIMEDCLLGGTRVSLPEDLLE
                     DPEIFFDVVSLSTWQEVLSDSQREHLQQFLPQFPTDTVEQQNELILALFSGENFRFGN
                     PLHIAQKLFRDGHFNPEVVKYRQLCFKSQYKRYLSSQQQYFHRLLRQILASRSDLLEM
                     ARTSGPALPFRHKHHSPSRSPEEREWRTQQRYLKVLREVKEECGDTALSSDEEDLSSW
                     LPSSPARSPSPAVPLRVVPTLSTTDMKTADKIELGDSDLKLMLKKHHEKRKHQPDHPD
                     LLTGDLTLSDIMTRVNAGRKGSLAALYDLAVLKKKVKEKEEKKKKKIKLIKSEAEDLA
                     EPLSNTEGVPTLSQAPSPLAISSIKEEPLEDIKPCLGINEISSSFFSLLLEILLLESQ
                     ASLPMLEDRVLDWQSSPASSLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVE
                     FKEKTQQWKLLGQSQDNEKELAALFHLWLETKDQAFCKENEDSSDAMTPVPRVRTDYV
                     VRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHS
                     LLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSTQVNTVVSG
                     ALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKARKALQQKPKPP
                     SKVKSSNKEGSVKGLSGPSEPSQMSLSDSSMPPTPVTPVTPTTPALPTPISPPPVSAV
                     SRSGSTTVSEPAKSSSGVLLVSSPTMPQLGTMLSPASIQTPPSSQTTARVVSHSSSAG
                     LPQVRVVAQPSLPAVSQQSVGPAQPLPQMPAGPQIRVPVTATQTKVVPQAVVATVPVK
                     GQTTAASVQRPGPAQTGLTVTSLPAAVSPGSKTAMSSPGSSAPSASTTAVIQNVTGQN
                     IIKQVSITGQLGVKPQTGNSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRITPD
                     MMATLAKSQVTTVKLTQDLFGAGSGTAGKGISATLHVTSNPVHAADSPAKAPSASVPS
                     SAPAGTTVVKVTPDLKPTETSSSAFRLMPALGVSVADQKGKNTVASSEAKPAATIRIV
                     QGLGVMPPKAGQTITVAAHAKQGASVAGGSGTVHSSTVSLPSINATVSKTVAVASGAT
                     STPISIGTGAPTVRQVPVNTTVVSTSQSGKLPTRITVPLSVISQPMKGKSVVTAPIIK
                     GNLGANLSGLGRNIILTTMPAGAKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVP
                     ASHLQQGTASGSSKAVSTVVVTTAPSPKQAPEQQ"
     exon            270..471
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            472..599
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            600..774
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            775..876
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            877..950
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1035
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1216
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..1325
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1452
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            1453..1518
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1598
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            1599..1642
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1703
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            1704..1878
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..1985
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            1986..2109
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            2110..2189
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            2190..2404
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            2405..2675
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            2676..2888
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            2889..3656
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            3657..3763
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            3764..3899
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
     exon            3900..5179
                     /gene="Nfrkb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggttcgcccc tacaggtccc gccccttccg ctgccggagc ccggaacgtg cgcgcaccca
       61 aactccttgc gggagcgagc gcgtccggga gcccacggcc ggacgagccc cggtgtacct
      121 gtggagaaga aacaatggat tccttggatc acatgctgac agatccccta gaacttggtc
      181 cttgtggaga tggtcacagt acagggatca tggaggactg ccttctgggt ggaaccaggg
      241 ttagtctgcc tgaagacctg ctggaggatc ctgaaatatt ctttgacgtc gtcagcctct
      301 ccacatggca ggaagtacta agtgactctc agcgtgaaca tctccagcag tttctgccgc
      361 agtttcctac agacactgta gagcagcaga atgagctcat ccttgcccta ttcagtgggg
      421 agaacttccg cttcggaaac cctctgcaca tcgcccagaa gctcttccga gatggacact
      481 ttaaccctga ggtggtcaag tatcggcagc tctgcttcaa gtcacagtac aagcggtacc
      541 tcagctccca acagcagtat ttccaccggc tgctgagaca gattcttgct tccagaagtg
      601 atctcctgga gatggctcgc acgagcggcc cggctcttcc ctttcgacac aagcaccatt
      661 caccatcccg aagcccggag gagcgggagt ggcggaccca gcagcgttac ctgaaagtct
      721 tgagggaagt gaaggaggag tgtggcgaca ctgccctgtc gtctgatgag gaggatctca
      781 gctcatggct tccaagctct ccagcacgct ctcctagtcc tgcggtgccc ctgagggtgg
      841 tgcccacgct ttccaccacg gatatgaaaa ctgcagataa aatagaactg ggggacagtg
      901 acctgaagtt aatgttaaag aaacaccatg agaagcggaa acatcaacca gatcacccag
      961 accttttgac aggggatctg actctcagcg acatcatgac tcgagtaaat gccggcagga
     1021 agggctctct agcagccttg tatgatttgg ctgttcttaa aaaaaaggtg aaggaaaagg
     1081 aggagaagaa aaagaagaaa ataaagttga ttaaatcgga ggcagaggat ctggctgagc
     1141 ccctaagcaa tactgaaggg gtcccaacgc tctcccaggc cccctctccc ctggcaatat
     1201 cgtctatcaa ggaagaaccc ctggaagaca tcaagccttg tcttggaatc aatgaaatat
     1261 cttccagttt tttctctctt ctgttagaga tcttgctgct ggagagtcag gctagccttc
     1321 ctatgctgga ggaccgggtt ttggattggc agtcttctcc agccagctcc ctcaacagct
     1381 ggttctctgc tgcccccaac tgggctgagt tggtgttgcc tgctctgcag tatcttgctg
     1441 gagaaagccg agcagttcct tccagttttt ctccatttgt tgaattcaaa gagaaaaccc
     1501 agcagtggaa attgcttggt caatctcaag ataatgaaaa ggaattagcc gctctcttcc
     1561 acttgtggct agaaaccaaa gaccaggctt tctgtaagga aaatgaagac agctcagatg
     1621 ccatgacacc tgtgcctcga gtaagaactg actatgtggt tcggcctagc acaggagagg
     1681 agaaacgggt ttttcaagag caggagcgtt acaggtatag ccaaccccat aaggcattca
     1741 cctttcgcat gcatggcttt gagtctgtgg tggggccagt gaagggcgtg tttgacaagg
     1801 agacctccct caacaaggct cgtgagcact cactgctgcg ctctgaccgg cctgcctatg
     1861 tcaccattct gtctcttgtt cgggatgctg cggctcggct gcctaatgga gaaggcactc
     1921 gggcagagat ctgtgagctg ctcaaggact ctcagtttct tgctcctgat gtcaccagca
     1981 ctcaggtgaa cacggtagtg agtggcgcac tggatcgatt gcattatgag aaggaccctt
     2041 gtgtgaaata cgacattggt cggaagctgt ggatctacct gcatcgtgac cggagtgagg
     2101 aagagtttga acggatccat caagctcaag cagcagcagc taaagccaga aaagctcttc
     2161 agcaaaaacc caaaccgcca tccaaggtga agtccagtaa taaggagggc tccgtgaagg
     2221 gccttagtgg tccttctgag cccagccaga tgagcctcag tgactccagc atgccaccta
     2281 ccccagttac gcctgtaacc cccaccacgc cagcattgcc tacccctatc tctcctccac
     2341 ctgtgtcagc ggtgagcaga agtggctcta ccactgtctc tgagccagcc aagtctagtt
     2401 caggtgttct tctggtgtcc tcaccaacaa tgccacagct aggaacgatg ctttcccctg
     2461 cttccatcca gactccgccc agttctcaga ccactgctcg ggttgtcagc cattccagct
     2521 cagcaggact gccccaggtt cgggtagtag cccagcccag ccttcctgct gtttcccagc
     2581 agtcagtagg gccagcacag ccactacccc agatgccagc aggaccacag atccgtgtgc
     2641 cagtcaccgc tacccaaacc aaagtagtac cccaggcagt tgtggctaca gttccagtca
     2701 aggggcagac tacagcggcc tctgtgcaac ggcctggacc tgcacagaca ggacttacag
     2761 tgacgagtct tcctgctgca gttagccccg ggagcaagac agccatgagt tctcctggga
     2821 gctctgctcc aagtgcctcc acaaccgccg tcattcagaa tgtcacagga cagaacatca
     2881 tcaagcaggt gtcaatcact ggacagcttg gtgtgaagcc ccagacaggc aacagcattc
     2941 cactcacagc cacaaacttc cgtatccagg gtaaagatgt actgcgcctg ccgccttctt
     3001 ccatcaccac agatgccaag ggccagacgg ttctgagaat cactccagac atgatggcca
     3061 cactggccaa gtctcaggtc accacagtca agttgactca ggacctcttt ggggcaggta
     3121 gcggcactgc aggcaaaggc atctctgcta ccttgcatgt gacttccaac cctgtccatg
     3181 cggctgacag ccctgccaag gccccttcag ccagtgttcc ttcatcagct ccagcgggca
     3241 ctaccgtggt caaagtaact cctgatctca agccaacaga aacctccagt tcagcttttc
     3301 gcttgatgcc agctcttggc gtgagtgtgg cagatcagaa ggggaagaac acagtggcct
     3361 cttcagaagc aaaacctgct gccacaatcc gcattgtgca ggggctggga gtgatgcctc
     3421 ctaaagcagg ccagaccatt actgttgcag cacatgcaaa gcaaggagcc tctgttgctg
     3481 gtgggtctgg aactgtccat tcttcaactg tgtccttacc cagtatcaat gccactgtgt
     3541 ctaagactgt ggctgtggct tctggagcaa caagcacccc catcagcatc gggactggag
     3601 cccccaccgt gcgacaggtt cctgttaaca ctacagttgt gtccacatcc cagtctggga
     3661 agctgcctac caggatcaca gttcctctct ctgtgattag ccagccaatg aagggcaaga
     3721 gcgtggtcac agcccccatc atcaaaggca accttggagc caatctcagt gggctgggtc
     3781 gcaacatcat cctcacaacc atgccagcgg gtgctaagct cattgctggc aataagccag
     3841 tgagtttcct caccgcccag cagttgcagc agcttcagca gcaaggtcag gctacacagg
     3901 tacgcatcca gactgtgcca gcatcccatc tgcaacaggg cacagcttcc ggctcctcca
     3961 aagccgtgtc cactgttgtt gtgaccacag ctccatctcc taaacaagca cctgagcagc
     4021 agtgactgag aagaaaggcg gcttctttaa gagaccaggc ctggtttatc tcggctgaca
     4081 gaaagggagc agggaggctg caccattctt ctgagctgtc ctgcttgagg cagggtggtg
     4141 gagagtgatg gcaactgtgg cctagattgt gctgccacac tccagagtga agcccttttt
     4201 agggttccag ggatgatctg ttatcctgga ctaccaggaa gagggaagga acatcagagt
     4261 ctggggaggt cacagtcaca caagccgggg ttacctcctg aatgttgggt tcccagggag
     4321 caggcctgcc agttggtgag tggaccggca gggaataagc ctcattctgt gtgaggattt
     4381 tactttttag tttctgatct tctccgtgac ttgttgagat gtgagttttg tgtccagaga
     4441 atttttgtgt aacttatttt tttaaagaac ctactctacg tcttttatca aatagaaacc
     4501 tgggcttcag tgcccctaaa ctgatcactt accccttcaa ccagaatgag agcatagcaa
     4561 gactcttaat agtttggcgg cttacttgat aatggagagg ttatatagta agaaaatgta
     4621 ggccttgagt tagcatggac cccctcaagt gggactagtt caatgccgtg tactaaatat
     4681 gggcatctga atctcggttg tccctatgtc ttctcttgtg ggcattgtcc ttgacaagcc
     4741 tgttcatgga agttcagagc ttttggacag gagtagggga agatgaggtg ctgctctcac
     4801 cgtgcacttg cttacagccc agacattgca cattctcctt gctgtagaac agccattgct
     4861 aaccagaccc ttggagctgg ccacttgact gggacagaga agaaatgggg aggtgggggc
     4921 aggggtaggc actgcctggc agtgccatct tgaggggaaa ggatgttttt attctggcca
     4981 tttcatattt ctcagccacc accagccaca gacagggctc agaagggtac tttacaaagt
     5041 ccaagtactt aatgtactag gtgtatctta acgtgtcttg ctgtggtgca ggggtgggta
     5101 ggaaaacctt tctgcaggga tagtgcttcc ctgtctcttt gtgaaaatat ccaaattatt
     5161 aaaaacatat ctttaattt
//
