LOCUS       NM_212509               1479 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus NFKB inhibitor like 1 (Nfkbil1), mRNA.
ACCESSION   NM_212509 XM_342089
VERSION     NM_212509.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1479)
  AUTHORS   Chiba,T., Miyashita,K., Sugoh,T., Warita,T., Inoko,H., Kimura,M.
            and Sato,T.
  TITLE     IkappaBL, a novel member of the nuclear IkappaB family, inhibits
            inflammatory cytokine expression
  JOURNAL   FEBS Lett 585 (22), 3577-3581 (2011)
   PUBMED   22024480
REFERENCE   2  (bases 1 to 1479)
  AUTHORS   Atzei,P., Gargan,S., Curran,N. and Moynagh,P.N.
  TITLE     Cactin targets the MHC class III protein IkappaB-like (IkappaBL)
            and inhibits NF-kappaB and interferon-regulatory factor signaling
            pathways
  JOURNAL   J Biol Chem 285 (47), 36804-36817 (2010)
   PUBMED   20829348
REFERENCE   3  (bases 1 to 1479)
  AUTHORS   Hurt,P., Walter,L., Sudbrak,R., Klages,S., Muller,I., Shiina,T.,
            Inoko,H., Lehrach,H., Gunther,E., Reinhardt,R. and Himmelbauer,H.
  TITLE     The genomic sequence and comparative analysis of the rat major
            histocompatibility complex
  JOURNAL   Genome Res 14 (4), 631-639 (2004)
   PUBMED   15060004
REFERENCE   4  (bases 1 to 1479)
  AUTHORS   Okamoto,K., Makino,S., Yoshikawa,Y., Takaki,A., Nagatsuka,Y.,
            Ota,M., Tamiya,G., Kimura,A., Bahram,S. and Inoko,H.
  TITLE     Identification of I kappa BL as the second major histocompatibility
            complex-linked susceptibility locus for rheumatoid arthritis
  JOURNAL   Am J Hum Genet 72 (2), 303-312 (2003)
   PUBMED   12509789
REFERENCE   5  (bases 1 to 1479)
  AUTHORS   Lambracht-Washington,D. and Fischer Lindahl,K.
  TITLE     Does the rat have an H2-D orthologue next to Bat1?
  JOURNAL   Immunogenetics 53 (12), 1039-1046 (2002)
   PUBMED   11904681
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX883046.1 and BC099772.1.
            
            On Oct 2, 2009 this sequence version replaced NM_212509.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099772.1, CK480351.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                BX883046.1         83595-83650         c
            57-1479             BC099772.1         1-1423
FEATURES             Location/Qualifiers
     source          1..1479
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1479
                     /gene="Nfkbil1"
                     /gene_synonym="IkBL"
                     /note="NFKB inhibitor like 1"
                     /db_xref="GeneID:361794"
                     /db_xref="RGD:1303310"
     exon            1..163
                     /gene="Nfkbil1"
                     /gene_synonym="IkBL"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..1252
                     /gene="Nfkbil1"
                     /gene_synonym="IkBL"
                     /note="ikappaBL; I-kappa-B-like protein; inhibitor of
                     kappa B-like protein; nuclear factor of kappa light
                     polypeptide gene enhancer in B-cells inhibitor-like 1;
                     putative inhibitor of Rel family transcription factors"
                     /codon_start=1
                     /product="NF-kappa-B inhibitor-like protein 1"
                     /protein_id="NP_997674.1"
                     /db_xref="GeneID:361794"
                     /db_xref="RGD:1303310"
                     /translation="MSNPSPQAPEEEASTSVCRPQSSMASVSRRHRRERRFRRYLSAG
                     RLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTAL
                     HAAARQGPNAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEDEEVS
                     KEREWRQKLQGELEDEWQEVIGRFEDDASRETQEPESFSAWSERLAREHAQKQRRQQL
                     EAEGSRRPPRAEGSSHSWRQQEEEQRLFRERARVKEKELCESRARRAQEAQGDRGPAP
                     PRARPRAEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALKRYL
                     RVQQVRWHPDRFLQRFRNQIETWELGRVMGAVTALSQALNRHAEALK"
     exon            164..440
                     /gene="Nfkbil1"
                     /gene_synonym="IkBL"
                     /inference="alignment:Splign:2.1.0"
     exon            441..662
                     /gene="Nfkbil1"
                     /gene_synonym="IkBL"
                     /inference="alignment:Splign:2.1.0"
     exon            663..1458
                     /gene="Nfkbil1"
                     /gene_synonym="IkBL"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccttgcgtgc ctcctccctc cacacctccc ttctccgagc gtccttaaac ccaggcctcc
       61 ggcctccgtc tctgagggtc cttgaggggg gcggggagca ggtctgatga gtaacccctc
      121 cccccaggcc ccagaggaag aagcctctac gtctgtctgt cggccccaga gttccatggc
      181 ctccgtttcc cgccggcacc gccgagagcg acgcttcagg cggtacttgt ctgcaggacg
      241 gctggtgcga gcccaggctc tcctccagcg acatcccggc cttgatgtgg atgctgggca
      301 gcccccgcct ctccacaggg cctgtgcccg ccacgatgcc cctgccctgt gcttgctgct
      361 gcgtcttggc gccgaccctg cccaccagga ccgccatggg gacacggcgc tgcatgctgc
      421 tgcccgccag ggccctaatg cttacacgga cttcttcctg ccactgctga gtcgatgccc
      481 atctgccatg ggcataaaga ataaggatgg ggagactcct gggcagattc taggctgggg
      541 acctccctgg gactctgctg aagaggaaga ggatgaggag gtttccaagg agcgggaatg
      601 gcggcagaag ctacaaggcg agctggagga tgagtggcag gaggtcatcg gaaggtttga
      661 agatgatgcc tcccgggaga cgcaggagcc cgagtccttc tcagcctggt cagagcgcct
      721 ggcccgagag catgcccaga agcagcggcg gcagcagctg gaggcagagg gatcccgccg
      781 acccccaagg gctgagggct ccagtcacag ctggcgacag caagaggagg agcagcggct
      841 tttccgggag cgagcccggg tcaaggagaa ggaactgtgt gagagccgag ccaggagggc
      901 ccaagaggct caaggggacc gagggccagc gcctcccagg gcccggccta gggcagagca
      961 ccctcgaggg gcagggaggg gcagcctctg gcgctttggc gatgtgccct ggccctgccc
     1021 tggtggaggg gacccagagg ccatggctgc agctttggtg gccaggggtc ccccactgga
     1081 ggaacaggga gctctgaaga ggtacttaag agtccagcag gtccgatggc accctgaccg
     1141 attcttgcag cgattccgaa accagattga gacctgggag ctgggccgtg tgatgggagc
     1201 cgtgacagcc ctttctcagg ccctgaaccg ccatgcagaa gccctcaagt gatcctaggg
     1261 aatgagcaag aacctgtggg gatgtagcct ccaggacaga tggaaggaag caaggtcgtg
     1321 gatggggatg gtcaagaggc cgctgccccg cagagaggat atgggatggc taacgtaatg
     1381 ggtgcgaggg tggggtgggg aaggctctac cactgctctg gactgccatt tcctaataag
     1441 acttggttcc acacctcaaa aaaaaaaaaa aaaaaaaaa
//
