LOCUS       NP_954542                365 aa            linear   ROD 20-MAR-2023
DEFINITION  NF-kappa-B inhibitor epsilon [Rattus norvegicus].
ACCESSION   NP_954542 XP_236939
VERSION     NP_954542.1
DBSOURCE    REFSEQ: accession NM_199111.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 365)
  AUTHORS   Hayden MS and Ghosh S.
  TITLE     Shared principles in NF-kappaB signaling
  JOURNAL   Cell 132 (3), 344-362 (2008)
   PUBMED   18267068
  REMARK    Review article
REFERENCE   2  (residues 1 to 365)
  AUTHORS   Shimazu D, Yamamoto N, Umino A, Ishii S, Sakurai S and Nishikawa T.
  TITLE     Inhibition of D-serine accumulation in the Xenopus oocyte by
            expression of the rat ortholog of human 3'-phosphoadenosine
            5'-phosphosulfate transporter gene isolated from the neocortex as
            D-serine modulator-1
  JOURNAL   J Neurochem 96 (1), 30-42 (2006)
   PUBMED   16277611
  REMARK    GeneRIF: D-serine modulator-1 is the rat orthologue of the human
            3'-phosphoadenosine 5'-phosphosulfate transporter 1 gene
REFERENCE   3  (residues 1 to 365)
  AUTHORS   Ishida N and Kawakita M.
  TITLE     Molecular physiology and pathology of the nucleotide sugar
            transporter family (SLC35)
  JOURNAL   Pflugers Arch 447 (5), 768-775 (2004)
   PUBMED   12759756
  REMARK    Review article
REFERENCE   4  (residues 1 to 365)
  AUTHORS   Kamiyama S, Suda T, Ueda R, Suzuki M, Okubo R, Kikuchi N, Chiba Y,
            Goto S, Toyoda H, Saigo K, Watanabe M, Narimatsu H, Jigami Y and
            Nishihara S.
  TITLE     Molecular cloning and identification of 3'-phosphoadenosine
            5'-phosphosulfate transporter
  JOURNAL   J Biol Chem 278 (28), 25958-25963 (2003)
   PUBMED   12716889
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC061795.1.
            
            On Jan 1, 2004 this sequence version replaced XP_236939.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061795.1, EV764951.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16093046 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q12"
     Protein         1..365
                     /product="NF-kappa-B inhibitor epsilon"
                     /note="nuclear factor of kappa light polypeptide gene
                     enhancer in B-cells inhibitor, epsilon; solute carrier
                     family 35, member B2"
                     /calculated_mol_wt=38998
     Region          122..359
                     /region_name="ANKYR"
                     /note="Ankyrin repeat [Signal transduction mechanisms];
                     COG0666"
                     /db_xref="CDD:440430"
     Region          123..156
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          160..189
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          191..232
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          235..265
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Site            order(236,240..241,244..246,248..249,253,256,265,268,270,
                     274..275,278..280,282..283,287,290,299,301,303,307..308,
                     311..313,315..316,320,323,335)
                     /site_type="other"
                     /note="oligomer interface [polypeptide binding]"
                     /db_xref="CDD:293786"
     Region          268..299
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          301..335
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     CDS             1..365
                     /gene="Nfkbie"
                     /gene_synonym="Slc35b2"
                     /coded_by="NM_199111.1:182..1279"
                     /db_xref="GeneID:316241"
                     /db_xref="RGD:735070"
ORIGIN      
        1 msdarkgpde addsqcdsgi eslrslrslp dpaaapvsgs shsgcpqpws hapktdkepe
       61 gkedadgera dstyassslt eslpllerpe akdpnpptps spvspagvls pqqlealtyi
      121 sedgdtllhl aviheapsvl fcclaflpqe vldiqnnlyq talhlavhld qpdvvralvl
      181 kgasrilqdq hgdtalhvac qrqnlacacc lleeqpepgr qpshpldlql knwqglaclh
      241 iatlqrnqpl ielllqngad idaqegtsgk talhlavetq erslvqfllq agarvdarml
      301 ngctplhlaa grglnsisst lceagadsll lnvedetpqd laedllsylp fddlkisgkp
      361 llctd
//
