LOCUS       NM_031567               1565 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus nuclear factor I/C (Nfic), mRNA.
ACCESSION   NM_031567 XM_001075535 XM_345789
VERSION     NM_031567.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1565)
  AUTHORS   Zhang F, Liang M, Zhao C, Fu Y and Yu S.
  TITLE     NFIC promotes the vitality and osteogenic differentiation of rat
            dental follicle cells
  JOURNAL   J Mol Histol 50 (5), 471-482 (2019)
   PUBMED   31432308
  REMARK    GeneRIF: pregulation of NFIC may promote the proliferation and
            osteogenic/cementogenic differentiation of dental follicle cells.
REFERENCE   2  (bases 1 to 1565)
  AUTHORS   Chen X, Chen G, Feng L, Jiang Z, Guo W, Yu M and Tian W.
  TITLE     Expression of Nfic during root formation in first mandibular molar
            of rat
  JOURNAL   J Mol Histol 45 (6), 619-626 (2014)
   PUBMED   25074584
  REMARK    GeneRIF: Nfic mRNA expression in dental papilla cells is elevated
            by the presence of Hertwig's epithelial root sheath cells.
REFERENCE   3  (bases 1 to 1565)
  AUTHORS   Lee HK, Lee DS, Park SJ, Cho KH, Bae HS and Park JC.
  TITLE     Nuclear factor I-C (NFIC) regulates dentin sialophosphoprotein
            (DSPP) and E-cadherin via control of Kruppel-like factor 4 (KLF4)
            during dentinogenesis
  JOURNAL   J Biol Chem 289 (41), 28225-28236 (2014)
   PUBMED   25138274
  REMARK    GeneRIF: NFIC regulates DSPP and E-cadherin via control of KLF4
            during dentinogenesis.
REFERENCE   4  (bases 1 to 1565)
  AUTHORS   Riffel AK, Schuenemann E and Vyhlidal CA.
  TITLE     Regulation of the CYP3A4 and CYP3A7 promoters by members of the
            nuclear factor I transcription factor family
  JOURNAL   Mol Pharmacol 76 (5), 1104-1114 (2009)
   PUBMED   19706729
REFERENCE   5  (bases 1 to 1565)
  AUTHORS   Royland JE and Kodavanti PR.
  TITLE     Gene expression profiles following exposure to a developmental
            neurotoxicant, Aroclor 1254: pathway analysis for possible mode(s)
            of action
  JOURNAL   Toxicol Appl Pharmacol 231 (2), 179-196 (2008)
   PUBMED   18602130
REFERENCE   6  (bases 1 to 1565)
  AUTHORS   Szpirer C, Van Vooren P, Riviere M, Scohy S, Collau G and Szpirer
            J.
  TITLE     Localization of 54 rat genes, and definition of new synteny groups
            conserved in the human and the rat
  JOURNAL   Mamm Genome 11 (9), 729-735 (2000)
   PUBMED   10967130
REFERENCE   7  (bases 1 to 1565)
  AUTHORS   Baumeister H, Gronostajski RM, Lyons GE and Margolis FL.
  TITLE     Identification of NFI-binding sites and cloning of NFI-cDNAs
            suggest a regulatory role for NFI transcription factors in
            olfactory neuron gene expression
  JOURNAL   Brain Res Mol Brain Res 72 (1), 65-79 (1999)
   PUBMED   10521600
REFERENCE   8  (bases 1 to 1565)
  AUTHORS   Osada S, Matsubara T, Daimon S, Terazu Y, Xu M, Nishihara T and
            Imagawa M.
  TITLE     Expression, DNA-binding specificity and transcriptional regulation
            of nuclear factor 1 family proteins from rat
  JOURNAL   Biochem J 342 (Pt 1) (Pt 1), 189-198 (1999)
   PUBMED   10432316
REFERENCE   9  (bases 1 to 1565)
  AUTHORS   Chaudhry AZ, Lyons GE and Gronostajski RM.
  TITLE     Expression patterns of the four nuclear factor I genes during mouse
            embryogenesis indicate a potential role in development
  JOURNAL   Dev Dyn 208 (3), 313-325 (1997)
   PUBMED   9056636
REFERENCE   10 (bases 1 to 1565)
  AUTHORS   Nehls MC, Grapilon ML and Brenner DA.
  TITLE     NF-I/Sp1 switch elements regulate collagen alpha 1(I) gene
            expression
  JOURNAL   DNA Cell Biol 11 (6), 443-452 (1992)
   PUBMED   1524678
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB012233.2.
            
            On or before May 24, 2007 this sequence version replaced
            XM_345789.3, XM_001075535.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB012233.2, SRR8487226.74840.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1565
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..1565
                     /gene="Nfic"
                     /note="nuclear factor I/C"
                     /db_xref="GeneID:29228"
                     /db_xref="RGD:62016"
     CDS             1..1320
                     /gene="Nfic"
                     /note="olfactory epithelium nuclear factor I-C"
                     /codon_start=1
                     /product="nuclear factor 1 C-type"
                     /protein_id="NP_113755.1"
                     /db_xref="GeneID:29228"
                     /db_xref="RGD:62016"
                     /translation="MYSSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKK
                     HEKRMSKDEERAVKDELLGEKAEVKQKWASRLLAKLRKDIRPECREDFVLAVTGKKAP
                     GCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLVKAAACAHP
                     VLCVQPHHIGVAVKELDLYLAYFVRERDAEQSSSPRTGVGSDQEDSKPITLDTTDFQE
                     SFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASAGMRRTLPSTSS
                     SGSKRHKSGSMEEDVDTSPGGDYYTSPNSPTSSSRNWTEDMEGGISSPVKKTEMDKSP
                     FNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPATPILPQTASTYFPHT
                     AIRYPPHLNPQDPLKDLVSLACDPATQQPGPPALRPARPLQTVPLWD"
     exon            1..30
                     /gene="Nfic"
                     /inference="alignment:Splign:2.1.0"
     exon            31..562
                     /gene="Nfic"
                     /inference="alignment:Splign:2.1.0"
     exon            563..634
                     /gene="Nfic"
                     /inference="alignment:Splign:2.1.0"
     exon            635..709
                     /gene="Nfic"
                     /inference="alignment:Splign:2.1.0"
     exon            710..833
                     /gene="Nfic"
                     /inference="alignment:Splign:2.1.0"
     exon            834..958
                     /gene="Nfic"
                     /inference="alignment:Splign:2.1.0"
     exon            959..1084
                     /gene="Nfic"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1269
                     /gene="Nfic"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1346
                     /gene="Nfic"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1565
                     /gene="Nfic"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtattcct ccccgctctg cctgacccag gatgagttcc acccattcat cgaggctctg
       61 ctgccgcatg tgcgtgcctt cgcctacacc tggttcaacc tgcaggcgcg caagcgcaag
      121 tacttcaaga agcacgagaa gcgcatgtcg aaggacgagg agcgcgcggt gaaggatgaa
      181 ctgctgggtg aaaaggccga ggtgaagcag aagtgggcgt cacggctgct ggccaagctg
      241 cgcaaggaca tccggcccga gtgccgcgaa gacttcgtac tggctgtgac aggcaagaag
      301 gcaccaggct gtgtgctgtc caacccggac cagaagggca agatgcggcg catcgactgc
      361 ctgcgccagg ctgacaaagt atggcgcctg gacctggtca tggtcatcct gttcaagggt
      421 atcccactgg agagcacgga cggcgagcgg ctggtgaagg ccgctgcctg cgcgcacccc
      481 gtgctgtgtg tgcagccgca ccatattggc gtggccgtca aggagctgga cctgtacctg
      541 gcctacttcg tgcgggagcg cgatgcggag cagagcagca gtccccggac aggagtgggc
      601 tcagaccagg aggacagcaa gcccattaca ctggacacga cagacttcca ggagagcttc
      661 gtcacatctg gcgtgttcag tgtcacggag ctgatccagg tgtctcggac acctgtggtg
      721 accggaaccg ggcccaactt ctccctggga gagctgcagg gccacctggc atacgacctg
      781 aacccagcca gcgctggcat gagaaggact ctacccagta cttcctccag tgggagcaag
      841 cggcacaagt cgggctcgat ggaggaggac gtggacacga gccctggcgg agactactac
      901 acatcaccca actcgcccac gagtagcagc cgcaactgga cggaagacat ggaaggaggc
      961 atctcatccc cggtgaagaa gacagagatg gacaaatctc cattcaacag cccatccccc
     1021 caggactccc cccggctctc cagcttcaca cagcaccaca ggcccgtcat cgcggtacac
     1081 agcggcatcg cgcggagccc ccacccgtcc tcagccctgc acttccctgc cacgcccatc
     1141 ctgccgcaga cagcctccac ctacttcccc cacactgcca tccggtaccc gccacatctc
     1201 aacccccagg acccactcaa ggatctggtg tccctggcct gcgacccggc cacccagcag
     1261 ccaggaccgc ctgctctccg cccggcacgt cccctgcaaa cagtcccttt gtgggattag
     1321 gacggaggga tcctcttgcg ggacagtcct ggtacctggg gtagcggagg ttgccttccc
     1381 acacctcctt catcgccggt ggagtcccag ggtgacagtc ccagcctgca tttttggtgg
     1441 aaaattagac gagtgagaag tcccctgcca actcccagct caatggcaat gacaggagga
     1501 gaaaggacaa aagacaaaca agaaacaaaa cccttcccaa ccaagatgaa aacacatggg
     1561 agctc
//
