LOCUS       NM_001398938            9112 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus nuclear factor I/B (Nfib), transcript variant 1,
            mRNA.
ACCESSION   NM_001398938 XM_006238336
VERSION     NM_001398938.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 9112)
  AUTHORS   Zhang,W.Q., Feng,L., Wang,H.J., Du,X.F., Hao,X.L., Li,Y.Z. and
            Cheng,L.
  TITLE     Inhibition of microRNA-495 inhibits hypoxia-induced apoptosis in
            H9c2 cells via targeting NFIB
  JOURNAL   Eur Rev Med Pharmacol Sci 25 (1), 335-343 (2021)
   PUBMED   33506922
  REMARK    GeneRIF: Inhibition of microRNA-495 inhibits hypoxia-induced
            apoptosis in H9c2 cells via targeting NFIB.
REFERENCE   2  (bases 1 to 9112)
  AUTHORS   Yang,B., Dong,R. and Zhao,H.
  TITLE     Inhibition of microRNA-346 inhibits myocardial inflammation and
            apoptosis after myocardial infarction via targeting NFIB
  JOURNAL   Eur Rev Med Pharmacol Sci 24 (22), 11752-11760 (2020)
   PUBMED   33275244
  REMARK    GeneRIF: Inhibition of microRNA-346 inhibits myocardial
            inflammation and apoptosis after myocardial infarction via
            targeting NFIB.
REFERENCE   3  (bases 1 to 9112)
  AUTHORS   Schanze,I., Bunt,J., Lim,J.W.C., Schanze,D., Dean,R.J., Alders,M.,
            Blanchet,P., Attie-Bitach,T., Berland,S., Boogert,S., Boppudi,S.,
            Bridges,C.J., Cho,M.T., Dobyns,W.B., Donnai,D., Douglas,J.,
            Earl,D.L., Edwards,T.J., Faivre,L., Fregeau,B., Genevieve,D.,
            Gerard,M., Gatinois,V., Holder-Espinasse,M., Huth,S.F., Izumi,K.,
            Kerr,B., Lacaze,E., Lakeman,P., Mahida,S., Mirzaa,G.M.,
            Morgan,S.M., Nowak,C., Peeters,H., Petit,F., Pilz,D.T.,
            Puechberty,J., Reinstein,E., Riviere,J.B., Santani,A.B.,
            Schneider,A., Sherr,E.H., Smith-Hicks,C., Wieland,I., Zackai,E.,
            Zhao,X., Gronostajski,R.M., Zenker,M. and Richards,L.J.
  TITLE     NFIB Haploinsufficiency Is Associated with Intellectual Disability
            and Macrocephaly
  JOURNAL   Am J Hum Genet 103 (5), 752-768 (2018)
   PUBMED   30388402
REFERENCE   4  (bases 1 to 9112)
  AUTHORS   Mellas,R.E., Kim,H., Osinski,J., Sadibasic,S., Gronostajski,R.M.,
            Cho,M. and Baker,O.J.
  TITLE     NFIB regulates embryonic development of submandibular glands
  JOURNAL   J Dent Res 94 (2), 312-319 (2015)
   PUBMED   25403566
REFERENCE   5  (bases 1 to 9112)
  AUTHORS   Archambaud,C., Nahori,M.A., Soubigou,G., Becavin,C., Laval,L.,
            Lechat,P., Smokvina,T., Langella,P., Lecuit,M. and Cossart,P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   6  (bases 1 to 9112)
  AUTHORS   Grunder,A., Ebel,T.T., Mallo,M., Schwarzkopf,G., Shimizu,T.,
            Sippel,A.E. and Schrewe,H.
  TITLE     Nuclear factor I-B (Nfib) deficient mice have severe lung
            hypoplasia
  JOURNAL   Mech Dev 112 (1-2), 69-77 (2002)
   PUBMED   11850179
REFERENCE   7  (bases 1 to 9112)
  AUTHORS   Baumeister,H., Gronostajski,R.M., Lyons,G.E. and Margolis,F.L.
  TITLE     Identification of NFI-binding sites and cloning of NFI-cDNAs
            suggest a regulatory role for NFI transcription factors in
            olfactory neuron gene expression
  JOURNAL   Brain Res Mol Brain Res 72 (1), 65-79 (1999)
   PUBMED   10521600
REFERENCE   8  (bases 1 to 9112)
  AUTHORS   Osada,S., Matsubara,T., Daimon,S., Terazu,Y., Xu,M., Nishihara,T.
            and Imagawa,M.
  TITLE     Expression, DNA-binding specificity and transcriptional regulation
            of nuclear factor 1 family proteins from rat
  JOURNAL   Biochem J 342 (Pt 1) (Pt 1), 189-198 (1999)
   PUBMED   10432316
REFERENCE   9  (bases 1 to 9112)
  AUTHORS   Liu,Y., Bernard,H.U. and Apt,D.
  TITLE     NFI-B3, a novel transcriptional repressor of the nuclear factor I
            family, is generated by alternative RNA processing
  JOURNAL   J Biol Chem 272 (16), 10739-10745 (1997)
   PUBMED   9099724
REFERENCE   10 (bases 1 to 9112)
  AUTHORS   Chaudhry,A.Z., Lyons,G.E. and Gronostajski,R.M.
  TITLE     Expression patterns of the four nuclear factor I genes during mouse
            embryogenesis indicate a potential role in development
  JOURNAL   Dev Dyn 208 (3), 313-325 (1997)
   PUBMED   9056636
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            [WARNING] On Apr 23, 2024 this sequence was replaced by
            NM_001398938.2.
            
            On Dec 28, 2021 this sequence version replaced XM_006238336.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB012230.2, SRR26643287.13440.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760393,
                                           SAMN12840107 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1049              JAXUCZ010000005.1  102018897-102019945 c
            1050-1581           JAXUCZ010000005.1  102012471-102013002 c
            1582-1635           JAXUCZ010000005.1  101896201-101896254 c
            1636-1704           JAXUCZ010000005.1  101874530-101874598 c
            1705-1825           JAXUCZ010000005.1  101868484-101868604 c
            1826-1944           JAXUCZ010000005.1  101865549-101865667 c
            1945-2079           JAXUCZ010000005.1  101846206-101846340 c
            2080-2264           JAXUCZ010000005.1  101843662-101843846 c
            2265-2403           JAXUCZ010000005.1  101839693-101839831 c
            2404-2486           JAXUCZ010000005.1  101836387-101836469 c
            2487-2575           JAXUCZ010000005.1  101825921-101826009 c
            2576-9112           JAXUCZ010000005.1  101805168-101811704 c
FEATURES             Location/Qualifiers
     source          1..9112
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q31"
     gene            1..9112
                     /gene="Nfib"
                     /note="nuclear factor I/B"
                     /db_xref="GeneID:29227"
                     /db_xref="RGD:62015"
     exon            1..1049
                     /gene="Nfib"
                     /inference="alignment:Splign:2.1.0"
     CDS             1020..2705
                     /gene="Nfib"
                     /note="isoform 1 is encoded by transcript variant 1;
                     olfactory epithelium nuclear factor I-B; nuclear factor 1
                     B-type"
                     /codon_start=1
                     /product="nuclear factor 1 B-type isoform 1"
                     /protein_id="NP_001385867.1"
                     /db_xref="GeneID:29227"
                     /db_xref="RGD:62015"
                     /translation="MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKK
                     HEKRMSKDEERAVKDELLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHP
                     CCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNP
                     ALCVQPHHITVSVKELDLFLAYYVQEQDSGQSGSPSHNDPAKNPPGYLEDSFVKSGVF
                     NVSELVRVSRTPITQGTGVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTIS
                     IDENMEPSPTGDFYPSPNSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSSTSPQDSSP
                     RLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPH
                     LNPQDTLKNYVPSYDPSSPQTSQPNSSGQVVGKVPGHFTPVLAPSPHPSAVRPVTLTM
                     TDTKPITTSTEAYTASGTSQANRYVGLSPRDPSFLHQQQLRICDWTMNQNGRHLYPST
                     SEDTLGITWQSPGTWASLVPFQVSNRTPILPANVQNYGLNIIGEPFLQAETSN"
     exon            1050..1581
                     /gene="Nfib"
                     /inference="alignment:Splign:2.1.0"
     exon            1582..1635
                     /gene="Nfib"
                     /inference="alignment:Splign:2.1.0"
     exon            1636..1704
                     /gene="Nfib"
                     /inference="alignment:Splign:2.1.0"
     exon            1705..1825
                     /gene="Nfib"
                     /inference="alignment:Splign:2.1.0"
     exon            1826..1944
                     /gene="Nfib"
                     /inference="alignment:Splign:2.1.0"
     exon            1945..2079
                     /gene="Nfib"
                     /inference="alignment:Splign:2.1.0"
     exon            2080..2264
                     /gene="Nfib"
                     /inference="alignment:Splign:2.1.0"
     exon            2265..2403
                     /gene="Nfib"
                     /inference="alignment:Splign:2.1.0"
     exon            2404..2486
                     /gene="Nfib"
                     /inference="alignment:Splign:2.1.0"
     exon            2487..2575
                     /gene="Nfib"
                     /inference="alignment:Splign:2.1.0"
     exon            2576..9112
                     /gene="Nfib"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcggggtcc agagggtgga accggtgaat ctttcaactt gcaagttttt caaggaaaga
       61 aagcgagaga gggaggggga aagcgcccag aacagaaaag aggagtttgc agccaagcgg
      121 gatcgatcgt ttgggatttt tttcaggagg tccttccgat cccttccgtg ggctgtgggc
      181 atcggcaccg gcagcggagt ccacgctcgg cgggtcagac gcggggcgag gcgggcgggc
      241 ggcggtgtgg cggggcagga gcgcagcaaa ggcttttccg cccgggagct ccgcgcctgc
      301 gccccctccc tcaccccggc ctctccctgc tcccccctcc ccacccccac ccggccctct
      361 ccggcgcgcg ccccgccacc cgcgcgcact cgcttgcgct ccccctcgcg cacacacatg
      421 gtcggctcgc ggcaaagttt cgcctgcgtt cgccactccc ggatcctgct gcagtattgg
      481 cggcggtaac cttgaacttt cccagcgcgg tgacacattc tcctcgcttt ccccaccgcc
      541 cggcctcctg cgcccccctc cccgcctttt tttaaaaaaa gcatttcacc acccaccacc
      601 accccaatcc aacacacgcc gaactctcgc gcaccccaag cccccaacaa caacaacaac
      661 aacaacaaca acaacaacaa caacaactgc aaaacagaaa acaaatcccc taaaccgggc
      721 gaccagcagc ctgcaccggc ggcggcctcg gagagctcgg ccggcgcgcg cggaccgcaa
      781 gagggttaaa agtgtagatt ggatttcacc ccgggaaatc tagctcgccg agtgaacttg
      841 aatctttggc tatttaagga ggactgggtt tgttgcgaag ttgcggtgat ccggcgcaga
      901 gccccgtcct gattgatcgc accgctgggc tcagatgact gtaaaatgaa tagatgaaat
      961 ccttgcttct cgaagatttt cttgggcatc tccgggaaag tgcgttttaa ggcgaagtca
     1021 tgatgtattc tcccatctgt ctcactcagg atgaattcca cccatttatt gaggcgcttc
     1081 ttccacacgt ccgtgcaatc gcctatacgt ggttcaacct gcaggctcga aaacgcaagt
     1141 actttaaaaa gcatgagaag cggatgtcga aggatgaaga aagagcagtc aaagatgagc
     1201 tgctcagtga aaagcctgaa atcaaacaga agtgggcatc caggctcctg gccaagctgc
     1261 gcaaagatat ccgccaggag taccgcgagg actttgtgct taccgtgact ggcaagaagc
     1321 acccgtgctg tgtcttatcc aatccagacc agaagggtaa gattaggagg atcgactgcc
     1381 tgcgacaggc agacaaagtc tggcgtctgg atctagtcat ggtgatcctg ttcaaaggca
     1441 tccctttgga gagtaccgat ggagagcgac ttatgaagtc cccacactgc acaaacccag
     1501 cactttgtgt gcagccgcac catatcacag tatcagttaa ggagcttgac ctgtttttgg
     1561 catactacgt gcaggagcaa gattctgggc aatcaggaag tccaagccac aatgatcctg
     1621 ccaagaatcc tccagggtac ctagaggaca gttttgtaaa atccggagtc ttcaacgtat
     1681 cagagcttgt gagagtatcc agaacaccca taacccaggg gactggagtc aacttcccaa
     1741 tcggagaaat ccccagccaa ccatactatc atgacatgaa ctctggcgtg aacctgcaga
     1801 ggtcgctgtc ttctccaccg agcagcaaaa gacccaaaac tatatccata gatgaaaata
     1861 tggagccaag tcctacagga gacttttacc cctctccaaa ttcaccagct gctggaagtc
     1921 gaacatggca tgagcgagat caagatatgt cttctccaac tacaatgaag aagcctgaga
     1981 agccactgtt tagctctaca tctccacagg attcttcccc aagattgagc acttttcccc
     2041 agcaccacca tcccggaata cctggagtcg cgcacagtgt catctcaact cgaactccac
     2101 ctccaccctc accgttgcca tttccaacgc aagctatcct tcctccagca ccatcaagtt
     2161 acttttctca tccaacaatc agatatcctc ctcacctgaa tcctcaggat actctgaaga
     2221 actatgtacc ttcttatgac ccgtccagtc ctcaaacgag ccagcctaac agcagtggtc
     2281 aagtagtagg gaaagtgcct ggccatttca cgcctgtctt ggcaccctct ccccatccca
     2341 gtgcagtgcg acctgtgacc ctgaccatga cagatactaa acccatcact acatccactg
     2401 aagcctacac agcctcaggc acatctcaag ccaatcgata tgtgggacta agcccaagag
     2461 acccatcctt cctgcatcag caacagctga ggatttgtga ctggaccatg aatcaaaacg
     2521 gcaggcattt ataccccagt accagtgagg atacattggg aattacttgg caaagtcctg
     2581 gtacctgggc tagcttggtt ccttttcaag tgtcaaatag gacacccatc ttaccggcaa
     2641 atgtccaaaa ttatggtttg aacataattg gagaaccttt ccttcaagcg gagacaagca
     2701 actgagggga aagaaacaca accatagtgt aagaaaatta ggggaaaaac acccaacaaa
     2761 agaaaagagg aagactggac aacagggaga aaggagagaa actgaagaaa gaagacgcta
     2821 gaccagcatt gcagcacttc cggtcactaa ttcccttaag gttgagactg tagtgacagg
     2881 aaagggtcaa tgacatctca ccgatgctag actgcagccc ctgcaccgta gcctttgttc
     2941 catgaagtcc gctgggaaat agatgttctg tctctatgac aatatatttt aactgacttt
     3001 ctagatgcct taatatttgc atgataagct agttttcttg gttagtattc ttgttgttta
     3061 cgcatggagt cactattcct ggttatctca acaacgaagg ctaggaggcg gcgtcagagg
     3121 ggctggggac agagccatga gccagccatt ttataagcac tctgatttct aaaagttaaa
     3181 aaaaattata tatatatata tataaaaatc tctgtagcct ttagttatcc gtacagattt
     3241 attaaatttt ggcccttaac ccagcctttt ccagtgtgta acccagtttg aaaatcttaa
     3301 aaaggaaaaa aaaagaaaac tagggaaaaa atggtttgaa ctcaaaggct ctatggaaga
     3361 aatgcctcta ggtgggtaaa gggttacctc tgcatgcaac agtaaaaatt aatataatat
     3421 tttccccaca aaagaaacac ttaacagagg caagtgcaat ttataaattt atatctaaag
     3481 gggaatcatg attataagtc cttcagccct tggactctaa attgagggga ttaaaaagaa
     3541 tttaaaataa ttttgagtga atttattttc ccctcagttt ttgagggcac ttaaaaaggc
     3601 attaaatcaa gacaaatcat gtgcttgaac agaaaaaaat aaaaaataaa aaaaaatatt
     3661 gaaaacacag cacttaggtt ggcttagctg cagcctcctc agaggtcgaa ttatttattt
     3721 aaaattactg gttgcatcaa gaacccatag ggtgtacaaa tggttctata caatctgcat
     3781 agtagagaca aagaggcagg ttaatccatg tcacaagggt aaagcttcca gtgtacaggc
     3841 tgggaacgcc agggcataga ataggaaaac acgctcttca gagaagtgcc atcagggtgc
     3901 tgggaacatg catggtgctt tcggacatta gccttgttca acacatttct cgtaatgaca
     3961 gatctatagt gtgcatgggc agacacatgt tgcctctatg tctcttaaaa ttttaattaa
     4021 aaagtactct ttccagtaat cctaatttgc acgaagatat aatgtccaca ttacgtgcct
     4081 tgccttgaaa tctaaaaaac aaaagacaaa aaaaaaaaat ccacaaaagt gacatcacta
     4141 cacttgtttt gctgcattta ttatcgtttt aaatctttac catttttatg acaaaatatt
     4201 ttgtactcca gacgaagaaa aatgtgtgac atcatggatt ttttagacag ttacaccttt
     4261 atctcacatt tataaagcat atcatggctg tgtatagttg ccgcttaaaa attgtaatcg
     4321 accagcaata ttttcagtat tttggtgttt tttctattaa cctttcatgt ttttcatctt
     4381 ccaattaata tttgggggga ggggtttcaa atttatacga attatgcaat accaagtttt
     4441 gcctatgtag gtagtgcttt tagctgtatt ggttattata ggtaagtaca cagatttaaa
     4501 aagaaataat gtatgctttt tttgtttgtt tgtttatttg tttgtttgtt ttaattgacc
     4561 aaagtgggta ctgctatttt tgcagtgtga tgaggtcctt ttgtgtactg agagatggac
     4621 aggggatttt ttttaatata catatataaa tatatatata ttccggggtg ggtgggagga
     4681 tttttaaccc tttacagtgt agctgtgaag cactgtaccc tgagataggt ctgggctgca
     4741 aagcgactgt tctgcctact gtgacaaact tcaacttaga caggttcccc tccccctgcc
     4801 cccactttcc cccctggggt gcaagctgaa ctcatttctg gttttcaatc taagaaacca
     4861 ggaagaaaaa gcaagcacag cacagcgaag cctcctagag gcagacttag aagaactgcc
     4921 ctgtcttatt ttagttgttg tcgatagttt ttcctgaaag ttccgaaacc acagtggaaa
     4981 gtgagcctgt ctcatctttg gcaaagacat ttcttgaagt gcccacatag cagatgttgg
     5041 ctgtttcaca cttttgagtt taacacagga atacgcttcc ttctaccaaa cgcattcgcc
     5101 catctggagg gagagcaccc ctgccccttc ctagcgctcc tccattttgt taatgacaga
     5161 tatgttgttc ctgtgactta ctacttcaaa tggatggcat tgcacttagg attttgtttt
     5221 ttggcatcca gaaggttgac cagacagaag gttgctcttc ttgaatgtat ttggaccgat
     5281 agattaaaat caaagttcag tttttaagga acaaaaataa gccagtcctt ttattctacc
     5341 tgcccttgta aactgagaag tagagcagag ggaaatgtag agttttaagc aactgatttt
     5401 cctgtggatg aatttaagcg tgtttgataa tgatgggagg aacttcttgt gaaggggtgg
     5461 tacttcaagt atatatttga attagtttcc cctgaggact agaggtgaat ggaaaccagt
     5521 tttattttgt cttcccctca ctttcacctg gtcctgttga gtgtatccat tactccaagg
     5581 agatctttca gaattagtga catacacagt cagctgccaa gaagccttct tgacccccac
     5641 cccaggccat gccctagtaa atgaactgtc aagtgtatgc atagcagatc gtttaatcgt
     5701 gagtacttta gaccagtgct cagaggcctg agaattgtac ctgaccagtc cattcagttt
     5761 catgtccacg tgctggatag cacagtcgga tgctaggatg caggttccaa gaaagtctag
     5821 ccatgtctgc gatatcagct gtgcagataa cagatcctct cagccaagct cttggtgtat
     5881 ttctgaccta tttgctgaag agtgtgaccc tacatgacac agcattcttt ccaggcagtc
     5941 ccctctcctt gtcaccagtg aatgaacaat tcatggcaca ctgtgggcaa ccctgccttc
     6001 ctcttgggta cagaggccta gggcaagtgt tccttttttt ttttttttta aacctagatc
     6061 aatttttctt ttctttgaga taaacttatt aaaaaagcac tactatagaa aatctcaaat
     6121 ccacttttag ccttctattt tttttttaaa ccaggaagta tattctgacg aagggcccca
     6181 cttttgcagg tcttgcacgc cccttcctta cccagactgc agagcttcag gatggtgaag
     6241 atcacccaag ggcatctgta gggggtggtg tctccagcca ccagctcaag gcactgtcca
     6301 gcctgtgttg tatttgcttt gcagcccacc actcccagtg cctctgaagt gtgttttccc
     6361 cagagtgacg tgagcagtcg agacttgcct aagggggaac agaaacctga gaggcagtga
     6421 aggagactgt acataaagac gtggcaaacc ttaagtatag caatatagtt accgggtgat
     6481 gttcgggtgg gcagctccat tataaagagt gtgaatgagt ctgtgaagct gcaattagca
     6541 agaagaacgt ggtcttctta atgaaccgcc taccttgtag acagtaattt gtacactgta
     6601 tagttttgtt aagaattttt ttttaaatta aagttcccat gtttgtaaag ctaacttttt
     6661 aacaattata atggaactgt atgttgtttc catttttaaa gtaaacaaga atattccttg
     6721 tttagagact ggactcgagt taaaactctc caggctctta agttatgtat taaaaaaaaa
     6781 atctgtccat gttaggagat atttcacaga ttcccatgct tgaaaagcat aggacactaa
     6841 tcctttaaaa aaagtgtaaa tggagaaaag ttatatttta tgaaggttat tttgttgtat
     6901 ttagtattgg aaaagttggt tttcagagca tttcagaatg tcggaagcac cactgtcctt
     6961 ttattagtat ataagatctt tagcaaacat tttctctctt ttttttttaa tggttattcc
     7021 atgatggtat ttaaggttac gtttcacaga gcattcagga taggcagaaa acaaagcagt
     7081 gctatgtctc acataacgtg tcctcaggga gcagaatctt ggatttgtga cttgtagctt
     7141 caaaaggact caacggcaga gactgcacgg gaacatcttg agcagcaaag cagggcatgt
     7201 tctctaccta gacgcagatt caatgtactg tgtgaacgga tgaaggctgc agaaagttac
     7261 cccatatcag tggacagtat tcattctccg tgaaacaact ctacaatctt gctggcagat
     7321 aggccccaag catgacattc aatatagttt acatgttcct gtcaaggtct tttgttaaca
     7381 ttaaccagct gcatgcttcc tggactttaa aaattggggt ttctatattt taaaaaaaaa
     7441 ttttttttat gtgcaggcta ttcaagttca atagtaaaaa ctcaaaattg aatgttctcc
     7501 tccatgctga aggagctgaa aactgccttc ttcatagttt gcactttctg gtagtcgccc
     7561 tgttttctct aactccttaa aattgtgtgg gtggagtgga tccctgcact gggggataac
     7621 atggaccact gattttgccc tttgaccctg cacaatgacc tttgcatcag ccaaactcat
     7681 tgccatgaca actctttgta ctgtgtcgtg ccacagatct gttggtcaca ttgttaatag
     7741 taaaggggac aagttggaga cggtcaattt ttacattttt ttttttgttg ttgcagtttt
     7801 tcttcaatgg ttgtaagtag tttttttttt tttttaatga taaaagggtt cagtagttaa
     7861 tactctttag aaatatctgt gtgttgcaat tcaaatgtat gttgagattg tgaaagcgct
     7921 tcagtggcac tagcctacgg ggaccctaga ttaagccttt gataactttt attgcatgat
     7981 acagtaccag taacaaaagg tggcctaaac acatgaaaag cagtgtaagc tagtgacact
     8041 aaagccagtc ttgtattact gtatttttga cagatggttt tgaaaactgt gctacaggga
     8101 ctgatgtggc aaatatatct ctttatgcag aaggaagtct tttttttttt ttaagaaaaa
     8161 aagaagtatg gcttattatg cattcttcat cgagggcatt gaagttgcat ggactgataa
     8221 aagttgatgc aaaatgagaa agaaacaaaa aacaaaaaca aaaaaaaaaa acaaaaaaca
     8281 aaaaaaccag caaaatgttt accaaaaaac tcaaacaaat gagcagtgcc tgttcaattt
     8341 cacagtctct gttgagttca gttgtaaata tgtttcaaat gacattttct tgggaaaaaa
     8401 aaaatctcta caacattgtg gaatgtgagg ggcaactgtc tcccgggcat aggcgtctca
     8461 aagctgcagt agattgcgcc ttgatcaggt ggttaatttg tgcttttatc acggagaact
     8521 ttgagcatcc tgggaagagg tgcccccacc tcaatgatat ttctctgaga acaacttttg
     8581 taggactgtg tgtttcttta gatacattta gtacaactgt aggtgacgag tagtcagtga
     8641 ttgcttgcta gctacacacc agggttgatc cattttaaaa cttttggcat tttgtcctcg
     8701 tgggccataa atacagaacc ttgtgtttta attagatttt cggggggaaa aggaggcaca
     8761 tgcataatct ccatgtaaca aacctttagc cgtgggatgt attatatgac agttacttaa
     8821 tttctggagt tcgggcctct gggataggcc cccagacggg gccagaatgt tagtgaaggt
     8881 tttattgtgc ccggttggag gataacgttc tttgtgtact ttttgtgggt cgcaaatgaa
     8941 ctcaattgcc acaagtttta aactggtgta aatcaagctt gacttaatgt gattgttact
     9001 gttatatcca gcctatactg ctagcagctg ctcatactgc agtcaattac tggaagcgga
     9061 tatatttcct atgcaaaaac tgtttaaaca ataaaatgag ctatgctaca ga
//
