LOCUS       NM_001007692            1498 bp    mRNA    linear   ROD 15-JUL-2024
DEFINITION  Rattus norvegicus nuclear factor of activated T-cells 2 interacting
            protein (Nfatc2ip), mRNA.
ACCESSION   NM_001007692 XM_219329
VERSION     NM_001007692.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1498)
  AUTHORS   Zhao,L., Qian,X., Ren,Z. and Wang,A.
  TITLE     miR-31-5p suppresses myocardial hypertrophy by targeting Nfatc2ip
  JOURNAL   J Cell Mol Med 28 (12), e18413 (2024)
   PUBMED   38894694
  REMARK    GeneRIF: miR-31-5p suppresses myocardial hypertrophy by targeting
            Nfatc2ip.
REFERENCE   2  (bases 1 to 1498)
  AUTHORS   Bettelli,E., Dastrange,M. and Oukka,M.
  TITLE     Foxp3 interacts with nuclear factor of activated T cells and
            NF-kappa B to repress cytokine gene expression and effector
            functions of T helper cells
  JOURNAL   Proc Natl Acad Sci U S A 102 (14), 5138-5143 (2005)
   PUBMED   15790681
REFERENCE   3  (bases 1 to 1498)
  AUTHORS   Rengarajan,J., Mittelstadt,P.R., Mages,H.W., Gerth,A.J.,
            Kroczek,R.A., Ashwell,J.D. and Glimcher,L.H.
  TITLE     Sequential involvement of NFAT and Egr transcription factors in
            FasL regulation
  JOURNAL   Immunity 12 (3), 293-300 (2000)
   PUBMED   10755616
REFERENCE   4  (bases 1 to 1498)
  AUTHORS   Hodge,M.R., Chun,H.J., Rengarajan,J., Alt,A., Lieberson,R. and
            Glimcher,L.H.
  TITLE     NF-AT-Driven interleukin-4 transcription potentiated by NIP45
  JOURNAL   Science 274 (5294), 1903-1905 (1996)
   PUBMED   8943202
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079050.1.
            
            On Nov 29, 2004 this sequence version replaced XM_219329.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079050.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1498
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q36"
     gene            1..1498
                     /gene="Nfatc2ip"
                     /note="nuclear factor of activated T-cells 2 interacting
                     protein"
                     /db_xref="GeneID:308983"
                     /db_xref="RGD:1359096"
     exon            1..490
                     /gene="Nfatc2ip"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..1366
                     /gene="Nfatc2ip"
                     /note="nuclear factor of activated T-cells, cytoplasmic
                     2-interacting protein; nuclear factor of activated
                     T-cells, cytoplasmic, calcineurin-dependent 2 interacting
                     protein"
                     /codon_start=1
                     /product="NFATC2-interacting protein"
                     /protein_id="NP_001007693.1"
                     /db_xref="GeneID:308983"
                     /db_xref="RGD:1359096"
                     /translation="MAEPLRRRGPRSRGGRASRGARRARAARGRCPRAPRSPTRLIPD
                     TVLVDLVSDSDEEVLEVVADPGEVPVARLPAPAAPEQDSDSDSEGAAEGPAGAPRTLV
                     RRRRRLLDPGEAPVVPVYSGKVQSSLNLIPDNSSLLKLCPSEPEDEADLTDSGSPPSE
                     DALPPGSPWKKKLRKKHEKEEKKMEEFPDQDISPLPQPSSRNKSRKHTEALQKLREVN
                     KRLQDLRSCLSPKQHQSPALQNTDDEVVLVEGSVLPQNPRLFTLKIRCRADLVRLPVK
                     TSEPLQNVVDHMASHLGVSPNRILLLFGETELSPTATPRTLKLGVADIIDCVVLASSS
                     EDTETSQELRLRVQGKEKHQMLEISLSPDSPLKVLMSHYEEAMGLSGHKLSFFFDGTK
                     LSGKELPTDLGLESGDLIEVWG"
     exon            491..563
                     /gene="Nfatc2ip"
                     /inference="alignment:Splign:2.1.0"
     exon            564..684
                     /gene="Nfatc2ip"
                     /inference="alignment:Splign:2.1.0"
     exon            685..765
                     /gene="Nfatc2ip"
                     /inference="alignment:Splign:2.1.0"
     exon            766..952
                     /gene="Nfatc2ip"
                     /inference="alignment:Splign:2.1.0"
     exon            953..1097
                     /gene="Nfatc2ip"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1207
                     /gene="Nfatc2ip"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..1474
                     /gene="Nfatc2ip"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagagcgtgt gggcgggaag aggtgatgac cggcaggctg ttcgtccaat gaaaggtaca
       61 gacgctaatg tggggtgccg gaggcttgta gaggccggtg tttgtggaag ctgtgtgaga
      121 gatggcggaa cccctgagaa gacgtggtcc gaggtcccgc ggtggccgcg ctagccgagg
      181 cgctcggaga gcccgagccg cccgtggccg gtgtcctcgc gccccgcggt ctccgactag
      241 gctcattcca gacaccgtgc ttgtggactt ggtcagtgac agcgacgaag aggttctgga
      301 agtggtcgcg gacccaggag aggtgcctgt cgcccgcctc cccgcaccgg ccgcacctga
      361 gcaggacagc gacagtgaca gtgaaggggc ggccgagggg cctgcaggag ccccgcgtac
      421 attggtccga cggcggcggc ggctgctgga tcccggggag gcgccggtgg ttcctgtgta
      481 ctctggaaag gtacagagca gcctcaacct cattcctgat aattcatccc tcttgaaact
      541 ttgtccctca gagcctgaag atgaggcaga tctgacagat tctggcagtc ctccctcaga
      601 ggatgccctg cctccaggtt ccccctggaa aaagaagctg aggaagaagc atgagaaaga
      661 agaaaagaaa atggaagagt ttccggacca ggacatctct cctttgcccc aaccgtcatc
      721 aaggaacaaa agcagaaagc ataccgaggc gctccagaag ttaagggaag tgaacaagcg
      781 tctccaagac ctccggtcct gcctgagccc caagcagcac cagagtccag cccttcagaa
      841 cacagatgat gaggtggtcc tagtggaagg gtctgtcttg ccacagaacc ctcgactctt
      901 tacactcaag atccggtgcc gggctgacct agtcagattg cctgtcaaga cgtcggagcc
      961 ccttcagaat gtggtggatc acatggccag tcatcttggg gtgtccccaa acaggattct
     1021 tttgctcttt ggagagacag agctgtcccc tactgccacc cctaggaccc taaagcttgg
     1081 agtggctgac atcattgatt gtgtggtgct agcaagttct tcagaggaca cagagacatc
     1141 ccaggagctt cggctccggg tgcaggggaa ggagaaacac cagatgttgg agatctcact
     1201 atctcctgat tctcctctta aggtcctcat gtcacactat gaggaagcca tgggactctc
     1261 tggacacaag ctctccttct tctttgatgg gacaaagctt tcaggcaagg agttgccgac
     1321 tgatctgggt ctggaatccg gagatctcat cgaagtctgg ggctgaagct ccctcactgt
     1381 gatcagacgc agagccaaga catgtggaca ttagttccca ctttcattat tattatttct
     1441 tgccccataa gggctaacag aagctgaact agaaaaaaaa aaaaaaaaaa aaaaaaaa
//
