LOCUS       XM_006251191            2111 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus NF2, moesin-ezrin-radixin like
            (MERLIN) tumor suppressor (Nf2), transcript variant X3, mRNA.
ACCESSION   XM_006251191
VERSION     XM_006251191.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051349.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XM_006251191.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2111
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2111
                     /gene="Nf2"
                     /gene_synonym="merlin"
                     /note="NF2, moesin-ezrin-radixin like (MERLIN) tumor
                     suppressor; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 8 ESTs, 1 long SRA read, 13
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 91 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:25744"
                     /db_xref="RGD:3169"
     CDS             439..1938
                     /gene="Nf2"
                     /gene_synonym="merlin"
                     /codon_start=1
                     /product="merlin isoform X3"
                     /protein_id="XP_006251253.1"
                     /db_xref="GeneID:25744"
                     /db_xref="RGD:3169"
                     /translation="MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGK
                     DLFDLVCRTLGLRETWFFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYP
                     ENAEEELVQEITQHLFFLQVKKQILDEKVYCPPEASVLLASYAVQAKYGDYDPSVHKR
                     GFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYG
                     VNYFTIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPL
                     DKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQM
                     ERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITE
                     EEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKE
                     ADQLKQDLQEAREAERRAKQKLLEIATKPTYPICTGAQTAQPWRQKSLA"
ORIGIN      
        1 gggtcgctga ggtgggggtt ggtagaggac gcttcccgag ggcgcgcgga gcggagccgg
       61 tgacagacac gcacgcgcgt gtgcgctccc aactactgcg cggccccgcg acccccgtgg
      121 gtcgctgaga ggcccggcgt cggcgccact gccgtctagg atttctgtct aagaggcgtc
      181 cccggcgtcc ccagcccgaa tctccaagct ccgggccgcg cccgctcttg ccggcgtccc
      241 gtacccccag cgtcagagcc agagccgggt cctcgcggcc catgctggcc gctggggacc
      301 caggcagcct aggtctgtct cctgccggcc agccggccac catggtggcc ctgaggcctg
      361 tgcagctact ccaggggggc taagagaccc agaacgcggg cctaggggta agggggtccc
      421 aggccagtac cccgcgccat ggccggagcc atcgcttccc gcatgagctt cagctcactc
      481 aagaggaagc agcccaagac attcacggtg cggatcgtca ccatggatgc cgagatggag
      541 ttcaactgcg agatgaagtg gaaagggaag gacctgtttg atttggtatg ccggacgctg
      601 gggcttcggg agacctggtt ctttggactg cagtatacaa tcaaggacac ggtggcctgg
      661 ctcaaaatgg acaagaaggt gttggatcac gatgtttcga aggaagaacc agttaccttt
      721 catttcctgg ccaaatttta tcctgaaaat gctgaggagg agctagtcca ggagatcacg
      781 cagcacttat ttttcttaca ggtgaagaag cagattttgg atgaaaaggt ctattgccct
      841 cctgaggcgt ccgtgctctt ggcgtcatat gctgttcagg ccaagtatgg cgactatgac
      901 ccctctgtgc acaagcgagg atttttagcc caagaggaat tgcttccgaa aagggtgata
      961 aatctctatc agatgactcc ggaaatgtgg gaggagagaa ttactgcttg gtatgcggag
     1021 caccggggca gagccaggga tgaagctgaa atggagtatt tgaagatagc tcaggacttg
     1081 gagatgtatg gcgtgaacta ctttacaatc cggaataaaa agggcacaga gttgctgctt
     1141 ggagtggatg ctctgggcct tcacatctac gaccctgaga acaggctgac ccccaagatc
     1201 tccttcccgt ggaatgaaat ccgaaacatc tcctacagcg acaaggagtt tactattaaa
     1261 ccactggata agaaaattga tgtctttaaa tttaactctt caaagcttcg tgttaataag
     1321 ctgattcttc agctgtgtat tgggaaccat gacctattta tgaggagaag gaaagctgac
     1381 tctttagaag ttcagcagat gaaagcccag gccagggaag agaaggcaag aaaacagatg
     1441 gagcggcagc ggctggctcg agaaaagcag atgcgggagg aggccgagcg cacgagagat
     1501 gagttagaga ggaggctcct gcagatgaaa gaggaagcaa cgatggccaa tgaagctctg
     1561 atgcggtctg aggaaacagc tgacctgttg gctgaaaagg ctcagatcac agaagaggag
     1621 gccaagcttc tggctcaaaa ggctgcagag gctgagcaag agatgcagcg aatcaaggcc
     1681 acagccattc ggacagagga ggagaagcgc ctgatggagc agaaggtgct ggaggctgaa
     1741 gtgctggcgt tgaagatggc tgaggagtca gagaggaggg ccaaggaggc tgatcagtta
     1801 aagcaagact tgcaggaagc ccgagaagca gagcgaagag ccaagcagaa gctcttagaa
     1861 atcgccacca agcccacata tccaatatgc acaggtgccc agacagccca gccttggagg
     1921 cagaaaagct tggcatgact gacttctgca gaggagcagg gaagagagga tggaatattc
     1981 tagcccatga acccaatccc agcaccactg cctcctgaca taccgagctt cgacattatt
     2041 ggtgacagct tgtcattcga cttcaaggac acggacatga agcgactttc catggagata
     2101 gagaaagaga a
//
