LOCUS       NM_001271254            2188 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus negative elongation factor complex member C/D
            (Nelfcd), mRNA.
ACCESSION   NM_001271254 XM_001055035 XM_003749639
VERSION     NM_001271254.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2188)
  AUTHORS   Kwak,H. and Lis,J.T.
  TITLE     Control of transcriptional elongation
  JOURNAL   Annu Rev Genet 47, 483-508 (2013)
   PUBMED   24050178
  REMARK    Review article
REFERENCE   2  (bases 1 to 2188)
  AUTHORS   Antunes,A.A., Leite,K.R., Reis,S.T., Sousa-Canavez,J.M.,
            Camara-Lopes,L.H., Dall'oglio,M.F. and Srougi,M.
  TITLE     GREB1 tissue expression is associated with organ-confined prostate
            cancer
  JOURNAL   Urol Oncol 30 (1), 16-20 (2012)
   PUBMED   19945309
REFERENCE   3  (bases 1 to 2188)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 2188)
  AUTHORS   Narita,T., Yamaguchi,Y., Yano,K., Sugimoto,S., Chanarat,S.,
            Wada,T., Kim,D.K., Hasegawa,J., Omori,M., Inukai,N., Endoh,M.,
            Yamada,T. and Handa,H.
  TITLE     Human transcription elongation factor NELF: identification of novel
            subunits and reconstitution of the functionally active complex
  JOURNAL   Mol Cell Biol 23 (6), 1863-1873 (2003)
   PUBMED   12612062
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On or before Sep 12, 2012 this sequence version replaced
            XM_001055035.3, XM_003749639.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.2549060.1,
                                           SRR26360172.597884.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-121               JAXUCZ010000003.1  183631968-183632088
            122-240             JAXUCZ010000003.1  183635774-183635892
            241-350             JAXUCZ010000003.1  183636097-183636206
            351-460             JAXUCZ010000003.1  183637380-183637489
            461-568             JAXUCZ010000003.1  183638123-183638230
            569-721             JAXUCZ010000003.1  183638590-183638742
            722-852             JAXUCZ010000003.1  183638911-183639041
            853-1018            JAXUCZ010000003.1  183639572-183639737
            1019-1153           JAXUCZ010000003.1  183640197-183640331
            1154-1293           JAXUCZ010000003.1  183640704-183640843
            1294-1408           JAXUCZ010000003.1  183641492-183641606
            1409-1504           JAXUCZ010000003.1  183641908-183642003
            1505-1645           JAXUCZ010000003.1  183642083-183642223
            1646-1775           JAXUCZ010000003.1  183642458-183642587
            1776-2188           JAXUCZ010000003.1  183642676-183643088
FEATURES             Location/Qualifiers
     source          1..2188
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q43"
     gene            1..2188
                     /gene="Nelfcd"
                     /note="negative elongation factor complex member C/D"
                     /db_xref="GeneID:679203"
                     /db_xref="RGD:1590753"
     exon            1..121
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..1810
                     /gene="Nelfcd"
                     /note="negative elongation factor complex member C/D,Th1l"
                     /codon_start=1
                     /product="negative elongation factor C/D"
                     /protein_id="NP_001258183.1"
                     /db_xref="GeneID:679203"
                     /db_xref="RGD:1590753"
                     /translation="MAGPAPGTIMGEDYFGNASEWGEEADGGQHQEEDSGEGEDDAEV
                     QQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQLLSENYTAVAQTVNLLAEWL
                     IQTGVEPVQVQETVENHLKSLLIKHFDPRKADSIFTEEGETPAWLEQMIAHTTWRDLF
                     YKLAEAHPDCLMLNFTVKLISDAGYQGEITSVSTACQQLEVFSRVLRTSLATILDGGE
                     ENLEKNLPEFAKMVCHGEHTYLFAQAMMSVLAQEEQGGSAVRRVAQEVQRFAQEKGHD
                     ASQITLALGTAASYPRACQALGAMLSRGALNPADITVLFKMFTSMDPPPVELIRVPAF
                     LDLFMQSLFKPGAKINQDHKHKYIHILAYAASVVETWKKNKRVSIGKDELKSTSKAVE
                     TVHNLCCNENKGASELVAELSTLYQCIRFPVVAMGVLKWVDWTVSEPRYFQLQTDHTP
                     VHLALLDEISTCHQLLHPQVLQLLVKLFETEHSQLDVMEQLELKKTLLDRMVHLLSRG
                     YVLPVVSYIRKCLEKLDTDISLIRYFVTEVLDVIAPPYTSDFVQLFLPILENDSIAGT
                     IKAEGEHDPVTEFIAHCKSNFIVVN"
     exon            122..240
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     exon            241..350
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     exon            351..460
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     exon            461..568
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     exon            569..721
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     exon            722..852
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     exon            853..1018
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1153
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1293
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1408
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1504
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     exon            1505..1645
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1775
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
     exon            1776..2188
                     /gene="Nelfcd"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgtccgcgc acgcgcagtg aagtcgcggc aaatatggcg ggtccagcgc cgggtacgat
       61 tatgggagaa gactacttcg ggaatgcgtc tgagtggggt gaagaggcgg acggcggcca
      121 gcatcaggaa gaagattctg gagaaggaga ggatgatgcc gaggtgcagc aggaatgtct
      181 gcataagttt tccacccggg actacatcat ggagccctcc atcttcaaca ctctgaagag
      241 gtatttccaa gcaggagggt ccccagaaaa tgtcatccag ctcttatctg agaactatac
      301 ggcggtggcc cagactgtga acctgctggc tgagtggctc attcagacag gtgttgagcc
      361 agtgcaggta caggagactg tggaaaacca cctcaagagt ttgctgatca agcactttga
      421 ccctcggaaa gcagattcta tcttcactga agaaggggag accccggctt ggcttgagca
      481 gatgatcgca cacaccacat ggagagatct gttttataag ttggctgagg cccatcctga
      541 ctgtttgatg ctcaacttca ctgtgaagct catctctgat gcaggctacc aaggtgagat
      601 caccagcgtg tccacggcct gccagcagct ggaagtgttc tccagagtgc tgcggacctc
      661 tctagccaca atcttggacg gaggagaaga aaacctggag aaaaatctcc ctgagtttgc
      721 aaagatggtg tgccatgggg aacacacgta cctgtttgcc caagccatga tgtccgtact
      781 ggcccaggag gaacagggtg gctctgcagt gcgcagggtc gctcaagaag tccagcgctt
      841 cgcccaggag aaaggtcatg atgccagcca gatcacactg gccttgggca cagctgcctc
      901 ctacccccgt gcctgccaag cccttggagc catgctgtcc aggggagccc tgaatcctgc
      961 agacatcacg gtcttgttca agatgttcac cagcatggac cctcctcctg tggagctcat
     1021 ccgggtgcca gccttcctgg acctgtttat gcagtcgctc ttcaagccag gggccaagat
     1081 caaccaggac cacaagcaca agtacattca catcctggct tacgctgcta gtgtggttga
     1141 gacctggaag aagaacaagc gggttagcat tggcaaagat gagctcaagt ccacgtcaaa
     1201 ggctgtagag accgtccaca atctgtgctg caatgagaac aaaggggcct ccgagctggt
     1261 ggctgagctg agcacacttt atcagtgcat taggtttcca gtggtagcaa tgggcgtgct
     1321 gaagtgggta gattggactg tgtctgagcc aaggtacttc cagctacaga ctgaccacac
     1381 tccggttcac ctggccttgt tggatgagat cagcacctgc caccagctcc tgcaccccca
     1441 ggtcctgcag ctgctcgtca agcttttcga gaccgagcac tcccagctag acgtgatgga
     1501 gcagctcgag ttaaaaaaga cgctgctgga caggatggtg cacctgctga gccgtggcta
     1561 cgtcctccct gtggtcagct acatccgcaa gtgtctggag aagctggaca cggacatctc
     1621 actcatccgc tactttgtca ctgaggttct ggacgtcatc gcccctccat acacctcaga
     1681 ctttgtgcaa cttttcctcc ccatcttgga aaacgacagc attgcaggca ccatcaaggc
     1741 agagggcgag catgaccccg tgacggagtt cattgctcac tgcaagtcta acttcatcgt
     1801 ggtgaactga gagcatccat tactgaagcc aaaccttagc caaaccctcc gtacccagct
     1861 cgggaggaca aggactggtc cagaaagccg ctctgtgaag aggctcaccc agcctcttgc
     1921 aagcagggcc tgctgggaag gagcaggcag ctcaaaggta gctgctatag tgacagcccc
     1981 tctgtattgc agtgtggctc acatgccggg taggtgtgtg ccacctctgg agaggagccc
     2041 agtgagccgc tgggtggtgg gtgtccagca gctgggtcac ttccatgaag ggtttctgta
     2101 ccttcccttc ctatgaccca gatggttgat cattttattg tttatgctac tctcatgtaa
     2161 ataaagtaca cagtgtggtg acgccaga
//
