LOCUS       NM_001098724            1772 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus N-terminal EF-hand calcium binding protein 3
            (Necab3), mRNA.
ACCESSION   NM_001098724 XM_001062462 XM_230761
VERSION     NM_001098724.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1772)
  AUTHORS   Yoo,J.C., Chang,J.R., Kim,S.H., Jang,S.K., Wolgemuth,D.J., Kim,K.
            and Rhee,K.
  TITLE     NIP1/XB51/NECAB3 is a potential substrate of Nek2, suggesting
            specific roles of Nek2 in Golgi
  JOURNAL   Exp Cell Res 292 (2), 393-402 (2004)
   PUBMED   14697346
REFERENCE   2  (bases 1 to 1772)
  AUTHORS   Sumioka,A., Imoto,S., Martins,R.N., Kirino,Y. and Suzuki,T.
  TITLE     XB51 isoforms mediate Alzheimer's beta-amyloid peptide production
            by X11L (X11-like protein)-dependent and -independent mechanisms
  JOURNAL   Biochem J 374 (Pt 1), 261-268 (2003)
   PUBMED   12780348
REFERENCE   3  (bases 1 to 1772)
  AUTHORS   Lee,D.S., Tomita,S., Kirino,Y. and Suzuki,T.
  TITLE     Regulation of X11L-dependent amyloid precursor protein metabolism
            by XB51, a novel X11L-binding protein
  JOURNAL   J Biol Chem 275 (30), 23134-23138 (2000)
   PUBMED   10833507
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB801563.1, CK598536.1, CO397705.1 and JAXUCZ010000003.1.
            
            On or before Jun 20, 2007 this sequence version replaced
            XM_230761.4, XM_001062462.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.19494.1,
                                           SRR26360190.2949498.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-412               CB801563.1         1-412
            413-938             CK598536.1         130-655
            939-1192            CO397705.1         461-714
            1193-1772           JAXUCZ010000003.1  163509683-163510262 c
FEATURES             Location/Qualifiers
     source          1..1772
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..1772
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /note="N-terminal EF-hand calcium binding protein 3"
                     /db_xref="GeneID:311562"
                     /db_xref="RGD:1310124"
     exon            1..105
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /inference="alignment:Splign:2.1.0"
     CDS             4..1059
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /note="amyloid beta (A4) precursor protein-binding, family
                     A, member 2 binding protein; amyloid beta (A4) precursor
                     protein-binding, family A, member 1 binding protein"
                     /codon_start=1
                     /product="N-terminal EF-hand calcium-binding protein 3"
                     /protein_id="NP_001092194.1"
                     /db_xref="GeneID:311562"
                     /db_xref="RGD:1310124"
                     /translation="MACAGLLTVCLLGPPAPQPTRHSAPAAGHALFQDVFRRADKNDD
                     GKLSFEEFQNYFADGVLSSAELRELFSGIDEQLTDNLETEKLCDYFSTHLGVYRPVLA
                     ALESLNRAVLTAMDTTKLEYEQASKVDQFVTRFLLRETANQLQALQNSLEGASDTLEA
                     QAQRLDEENIKVQSRSCGSRRAGRRALRSISWSPTWSPGSSDTGRSSEAELQWRLQVN
                     RLQELIDQLECKAPRLEPMHEGDLAKGLDSHILVAQRQVQVAEDALQDFHRALCCYMN
                     FTGAQSHCLHVSAQKMLDNAAFTLYEFWQDEASWRRHQQSPCSKAFQRTLIDHLRAPD
                     TLTTVFFPASWWIMNNN"
     exon            106..130
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            131..239
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            240..265
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            266..363
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            364..494
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            495..613
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            614..693
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            694..747
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            748..860
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            861..938
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1030
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1772
                     /gene="Necab3"
                     /gene_synonym="Apba2bp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccatggcgt gcgctgggct gctcactgtg tgcctgcttg ggccacctgc gccccagccg
       61 acgcgacact ctgcgcctgc cgcgggacac gcgctttttc aggacgtttt ccgcagagca
      121 gacaagaatg atgatggtaa gctctcgttt gaagaattcc agaattactt tgccgatggg
      181 gttctcagct ctgcggagct gcgggaactg ttcagcggca tcgatgagca gcttactgac
      241 aatttagaaa cagagaaact gtgtgactat ttctccacac acctgggtgt ctatcggcct
      301 gtgctggctg cgctggagtc tctgaaccgt gcggtgctca ctgccatgga cacgacaaag
      361 ctggagtatg aacaggcctc caaggtggac cagtttgtca cacgattcct gctgcgggag
      421 actgcgaatc agctacaagc cctacagaac tccctggagg gggcatcaga cactctggag
      481 gcccaggccc agcggttgga tgaagaaaat atcaaagtgc agagtaggtc ctgtggcagt
      541 cggagggcag gacgcagagc cctgaggagc atcagttggt caccaacctg gtctcctgga
      601 tcctctgata cagggcggag ttcagaggct gagctgcagt ggcggctgca ggtcaaccgc
      661 ctccaagagc tcatagacca gcttgagtgc aaggcaccac ggttggaacc catgcatgaa
      721 ggggaccttg ccaagggtct tgactcacac atccttgtag cacagaggca agtacaagtg
      781 gcagaggatg ccctgcagga tttccatcgt gctctgtgct gctacatgaa cttcacagga
      841 gcccaaagcc actgtctgca tgtatctgcc cagaagatgc tagacaatgc tgctttcacc
      901 ctatatgagt tctggcagga tgaggcctcc tggagaaggc accagcagtc accctgcagc
      961 aaggctttcc agcgcaccct cattgatcac ctgcgggcgc cagacactct caccactgtg
     1021 ttcttcccag cctcctggtg gattatgaat aataactgag tcgctggtga ctatagccct
     1081 gcctattact ctagagcccg ttgcactggc caactctacg ctaagatcaa ggagtctgcc
     1141 tgttcccagg ctaaaggcct ggtcagctgg tacagggtct ctcagcccag gaatcaggag
     1201 ccaggccgtt tgcttgcttt atttatttta ctgtttgtaa cttccaagca cctgggcttc
     1261 tgcctgattc aggaaaccca gattctggtc tccctttcct ctaccttgct gtgtgaccca
     1321 ggcagatccc tcacctctct ggctgcctag gggagttctt ctttctgctt actgctttgg
     1381 ggttatgttt ctgttcttcc tcaatcagtg gcagaaccag ggctgatgct cagggacccc
     1441 cctcaaaccc tggaaccttg acccttaagg ccatgccaac acagtgcata gtgtagagac
     1501 ctgggtgtct atcaccctgg ggtcagtcct aacatttcta gcattagtag ttgtaccaga
     1561 gacctctgga agatcctggg ttggtttgca tgtcatttac atatcatttg catgctcata
     1621 ccccacccat tctcagggca ctatgggaag ccccaagatg accttgcaaa gtagcaataa
     1681 tttgggccta gagttgcctg ctgcccccca gagatctctg aaccccagcc tgggtcttca
     1741 gcacagaggc aataaagttg gtagtcacct gt
//
