LOCUS       NM_001419519           23357 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus nebulin (Neb), mRNA.
ACCESSION   NM_001419519
VERSION     NM_001419519.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 23357)
  AUTHORS   Wei,J.H., Chang,N.C., Chen,S.P., Geraldine,P., Jayakumar,T. and
            Fong,T.H.
  TITLE     Comparative decline of the protein profiles of nebulin in response
            to denervation in skeletal muscle
  JOURNAL   Biochem Biophys Res Commun 466 (1), 95-102 (2015)
   PUBMED   26325472
  REMARK    GeneRIF: The results revealed that denervation induced muscle
            atrophy is accompanied by decreased nebulin content in a
            time-dependent manner.
REFERENCE   2  (bases 1 to 23357)
  AUTHORS   Gokhin,D.S., Lewis,R.A., McKeown,C.R., Nowak,R.B., Kim,N.E.,
            Littlefield,R.S., Lieber,R.L. and Fowler,V.M.
  TITLE     Tropomodulin isoforms regulate thin filament pointed-end capping
            and skeletal muscle physiology
  JOURNAL   J Cell Biol 189 (1), 95-109 (2010)
   PUBMED   20368620
REFERENCE   3  (bases 1 to 23357)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (bases 1 to 23357)
  AUTHORS   Pappas,C.T., Bhattacharya,N., Cooper,J.A. and Gregorio,C.C.
  TITLE     Nebulin interacts with CapZ and regulates thin filament
            architecture within the Z-disc
  JOURNAL   Mol Biol Cell 19 (5), 1837-1847 (2008)
   PUBMED   18272787
  REMARK    GeneRIF: Nebulin interacts with CapZ to from a thin filament of an
            adjacent sarcomere, thus providing a structural link between
            sarcomeres.
REFERENCE   5  (bases 1 to 23357)
  AUTHORS   Moncman,C.L. and Andrade,F.H.
  TITLE     Nebulin isoforms of extraocular muscle
  JOURNAL   Cell Tissue Res 327 (2), 415-420 (2007)
   PUBMED   17053899
  REMARK    GeneRIF: Extraocular muscle does not express nebulette and contains
            a nebulin isoform with a mass consistent with that found in the
            prototypical fast hindlimb muscle extensor digitorum longus.
REFERENCE   6  (bases 1 to 23357)
  AUTHORS   Horowits,R.
  TITLE     Nebulin regulation of actin filament lengths: new angles
  JOURNAL   Trends Cell Biol 16 (3), 121-124 (2006)
   PUBMED   16480876
  REMARK    GeneRIF: Nebulin knockdown leads to loss of actin filament-length
            regulation in cardiomyocytes, providing functional evidence that is
            consistent with the molecular ruler concept.
REFERENCE   7  (bases 1 to 23357)
  AUTHORS   McElhinny,A.S., Schwach,C., Valichnac,M., Mount-Patrick,S. and
            Gregorio,C.C.
  TITLE     Nebulin regulates the assembly and lengths of the thin filaments in
            striated muscle
  JOURNAL   J Cell Biol 170 (6), 947-957 (2005)
   PUBMED   16157704
  REMARK    GeneRIF: Nebulin regulates the assembly and lengths of the thin
            filaments in striated muscle.
REFERENCE   8  (bases 1 to 23357)
  AUTHORS   Chen,S.P., Sheu,J.R., Lai,C.Y., Lin,T.Y., Hsiao,G. and Fong,T.H.
  TITLE     Detection of myofibrillar proteins using a step gradient minigel
            with an ambiguous interface
  JOURNAL   Anal Biochem 338 (2), 270-277 (2005)
   PUBMED   15745747
REFERENCE   9  (bases 1 to 23357)
  AUTHORS   Young,P., Ferguson,C., Banuelos,S. and Gautel,M.
  TITLE     Molecular structure of the sarcomeric Z-disk: two types of titin
            interactions lead to an asymmetrical sorting of alpha-actinin
  JOURNAL   EMBO J 17 (6), 1614-1624 (1998)
   PUBMED   9501083
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760386
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                JAXUCZ010000003.1  57220631-57220709   c
            80-161              JAXUCZ010000003.1  57219989-57220070   c
            162-226             JAXUCZ010000003.1  57219418-57219482   c
            227-268             JAXUCZ010000003.1  57215776-57215817   c
            269-469             JAXUCZ010000003.1  57213983-57214183   c
            470-577             JAXUCZ010000003.1  57212213-57212320   c
            578-682             JAXUCZ010000003.1  57211667-57211771   c
            683-787             JAXUCZ010000003.1  57210634-57210738   c
            788-892             JAXUCZ010000003.1  57209906-57210010   c
            893-997             JAXUCZ010000003.1  57205207-57205311   c
            998-1102            JAXUCZ010000003.1  57201471-57201575   c
            1103-1210           JAXUCZ010000003.1  57200766-57200873   c
            1211-1327           JAXUCZ010000003.1  57197323-57197439   c
            1328-1432           JAXUCZ010000003.1  57195853-57195957   c
            1433-1540           JAXUCZ010000003.1  57195651-57195758   c
            1541-1645           JAXUCZ010000003.1  57195442-57195546   c
            1646-1744           JAXUCZ010000003.1  57194899-57194997   c
            1745-1849           JAXUCZ010000003.1  57193702-57193806   c
            1850-1957           JAXUCZ010000003.1  57192424-57192531   c
            1958-2071           JAXUCZ010000003.1  57192085-57192198   c
            2072-2173           JAXUCZ010000003.1  57191026-57191127   c
            2174-2278           JAXUCZ010000003.1  57190628-57190732   c
            2279-2377           JAXUCZ010000003.1  57189354-57189452   c
            2378-2482           JAXUCZ010000003.1  57187234-57187338   c
            2483-2590           JAXUCZ010000003.1  57186591-57186698   c
            2591-2704           JAXUCZ010000003.1  57185846-57185959   c
            2705-2902           JAXUCZ010000003.1  57183338-57183535   c
            2903-3010           JAXUCZ010000003.1  57181135-57181242   c
            3011-3109           JAXUCZ010000003.1  57178944-57179042   c
            3110-3214           JAXUCZ010000003.1  57178577-57178681   c
            3215-3322           JAXUCZ010000003.1  57178389-57178496   c
            3323-3634           JAXUCZ010000003.1  57176468-57176779   c
            3635-3841           JAXUCZ010000003.1  57176185-57176391   c
            3842-3946           JAXUCZ010000003.1  57175099-57175203   c
            3947-4054           JAXUCZ010000003.1  57174270-57174377   c
            4055-4366           JAXUCZ010000003.1  57172449-57172760   c
            4367-4573           JAXUCZ010000003.1  57171322-57171528   c
            4574-4678           JAXUCZ010000003.1  57169575-57169679   c
            4679-4786           JAXUCZ010000003.1  57167902-57168009   c
            4787-5098           JAXUCZ010000003.1  57166871-57167182   c
            5099-5305           JAXUCZ010000003.1  57165786-57165992   c
            5306-5410           JAXUCZ010000003.1  57165259-57165363   c
            5411-5518           JAXUCZ010000003.1  57165050-57165157   c
            5519-5830           JAXUCZ010000003.1  57164196-57164507   c
            5831-6037           JAXUCZ010000003.1  57162841-57163047   c
            6038-6142           JAXUCZ010000003.1  57160352-57160456   c
            6143-6250           JAXUCZ010000003.1  57159380-57159487   c
            6251-6562           JAXUCZ010000003.1  57157907-57158218   c
            6563-6769           JAXUCZ010000003.1  57157569-57157775   c
            6770-6874           JAXUCZ010000003.1  57156880-57156984   c
            6875-6982           JAXUCZ010000003.1  57154256-57154363   c
            6983-7294           JAXUCZ010000003.1  57150670-57150981   c
            7295-7498           JAXUCZ010000003.1  57150271-57150474   c
            7499-7603           JAXUCZ010000003.1  57146674-57146778   c
            7604-7711           JAXUCZ010000003.1  57145437-57145544   c
            7712-8023           JAXUCZ010000003.1  57144808-57145119   c
            8024-8227           JAXUCZ010000003.1  57144263-57144466   c
            8228-8332           JAXUCZ010000003.1  57143925-57144029   c
            8333-8440           JAXUCZ010000003.1  57143736-57143843   c
            8441-8752           JAXUCZ010000003.1  57135546-57135857   c
            8753-8956           JAXUCZ010000003.1  57134946-57135149   c
            8957-9061           JAXUCZ010000003.1  57134392-57134496   c
            9062-9169           JAXUCZ010000003.1  57131358-57131465   c
            9170-9481           JAXUCZ010000003.1  57128879-57129190   c
            9482-9685           JAXUCZ010000003.1  57126875-57127078   c
            9686-9790           JAXUCZ010000003.1  57126472-57126576   c
            9791-9898           JAXUCZ010000003.1  57124964-57125071   c
            9899-10210          JAXUCZ010000003.1  57123570-57123881   c
            10211-10414         JAXUCZ010000003.1  57122941-57123144   c
            10415-10519         JAXUCZ010000003.1  57122029-57122133   c
            10520-10627         JAXUCZ010000003.1  57117464-57117571   c
            10628-10939         JAXUCZ010000003.1  57116134-57116445   c
            10940-11143         JAXUCZ010000003.1  57114703-57114906   c
            11144-11248         JAXUCZ010000003.1  57113151-57113255   c
            11249-11356         JAXUCZ010000003.1  57111778-57111885   c
            11357-11668         JAXUCZ010000003.1  57110224-57110535   c
            11669-11872         JAXUCZ010000003.1  57108529-57108732   c
            11873-11977         JAXUCZ010000003.1  57107298-57107402   c
            11978-12085         JAXUCZ010000003.1  57107052-57107159   c
            12086-12397         JAXUCZ010000003.1  57106222-57106533   c
            12398-12601         JAXUCZ010000003.1  57105412-57105615   c
            12602-12706         JAXUCZ010000003.1  57104055-57104159   c
            12707-12814         JAXUCZ010000003.1  57103025-57103132   c
            12815-13126         JAXUCZ010000003.1  57101253-57101564   c
            13127-13330         JAXUCZ010000003.1  57100318-57100521   c
            13331-13435         JAXUCZ010000003.1  57099234-57099338   c
            13436-13543         JAXUCZ010000003.1  57098506-57098613   c
            13544-13855         JAXUCZ010000003.1  57097361-57097672   c
            13856-14059         JAXUCZ010000003.1  57095158-57095361   c
            14060-14164         JAXUCZ010000003.1  57094740-57094844   c
            14165-14269         JAXUCZ010000003.1  57091434-57091538   c
            14270-14581         JAXUCZ010000003.1  57091015-57091326   c
            14582-14686         JAXUCZ010000003.1  57090039-57090143   c
            14687-14785         JAXUCZ010000003.1  57088634-57088732   c
            14786-14887         JAXUCZ010000003.1  57088368-57088469   c
            14888-14995         JAXUCZ010000003.1  57088147-57088254   c
            14996-15307         JAXUCZ010000003.1  57087176-57087487   c
            15308-15412         JAXUCZ010000003.1  57086046-57086150   c
            15413-15517         JAXUCZ010000003.1  57085831-57085935   c
            15518-15622         JAXUCZ010000003.1  57085316-57085420   c
            15623-15730         JAXUCZ010000003.1  57084270-57084377   c
            15731-15844         JAXUCZ010000003.1  57084053-57084166   c
            15845-16042         JAXUCZ010000003.1  57083434-57083631   c
            16043-16147         JAXUCZ010000003.1  57083061-57083165   c
            16148-16252         JAXUCZ010000003.1  57082263-57082367   c
            16253-16357         JAXUCZ010000003.1  57082060-57082164   c
            16358-16465         JAXUCZ010000003.1  57081671-57081778   c
            16466-16579         JAXUCZ010000003.1  57079767-57079880   c
            16580-16777         JAXUCZ010000003.1  57079086-57079283   c
            16778-16882         JAXUCZ010000003.1  57078658-57078762   c
            16883-16987         JAXUCZ010000003.1  57077974-57078078   c
            16988-17095         JAXUCZ010000003.1  57076906-57077013   c
            17096-17200         JAXUCZ010000003.1  57075236-57075340   c
            17201-17308         JAXUCZ010000003.1  57073693-57073800   c
            17309-17413         JAXUCZ010000003.1  57073078-57073182   c
            17414-17518         JAXUCZ010000003.1  57072873-57072977   c
            17519-17617         JAXUCZ010000003.1  57071852-57071950   c
            17618-17728         JAXUCZ010000003.1  57071367-57071477   c
            17729-17833         JAXUCZ010000003.1  57070676-57070780   c
            17834-17938         JAXUCZ010000003.1  57069984-57070088   c
            17939-18043         JAXUCZ010000003.1  57069438-57069542   c
            18044-18148         JAXUCZ010000003.1  57067352-57067456   c
            18149-18253         JAXUCZ010000003.1  57067117-57067221   c
            18254-18358         JAXUCZ010000003.1  57066290-57066394   c
            18359-18463         JAXUCZ010000003.1  57065033-57065137   c
            18464-18568         JAXUCZ010000003.1  57063571-57063675   c
            18569-18673         JAXUCZ010000003.1  57062827-57062931   c
            18674-18778         JAXUCZ010000003.1  57061327-57061431   c
            18779-18886         JAXUCZ010000003.1  57060891-57060998   c
            18887-18991         JAXUCZ010000003.1  57059729-57059833   c
            18992-19096         JAXUCZ010000003.1  57058226-57058330   c
            19097-19201         JAXUCZ010000003.1  57057767-57057871   c
            19202-19306         JAXUCZ010000003.1  57056993-57057097   c
            19307-19417         JAXUCZ010000003.1  57056792-57056902   c
            19418-19528         JAXUCZ010000003.1  57056062-57056172   c
            19529-19630         JAXUCZ010000003.1  57055744-57055845   c
            19631-19735         JAXUCZ010000003.1  57055548-57055652   c
            19736-19846         JAXUCZ010000003.1  57052957-57053067   c
            19847-19951         JAXUCZ010000003.1  57052375-57052479   c
            19952-20056         JAXUCZ010000003.1  57051572-57051676   c
            20057-20161         JAXUCZ010000003.1  57050130-57050234   c
            20162-20272         JAXUCZ010000003.1  57047673-57047783   c
            20273-20383         JAXUCZ010000003.1  57047098-57047208   c
            20384-20497         JAXUCZ010000003.1  57046401-57046514   c
            20498-20602         JAXUCZ010000003.1  57045394-57045498   c
            20603-20707         JAXUCZ010000003.1  57044435-57044539   c
            20708-20812         JAXUCZ010000003.1  57043731-57043835   c
            20813-20905         JAXUCZ010000003.1  57043017-57043109   c
            20906-20998         JAXUCZ010000003.1  57041867-57041959   c
            20999-21091         JAXUCZ010000003.1  57039907-57039999   c
            21092-21184         JAXUCZ010000003.1  57039371-57039463   c
            21185-21277         JAXUCZ010000003.1  57038391-57038483   c
            21278-21370         JAXUCZ010000003.1  57037393-57037485   c
            21371-21463         JAXUCZ010000003.1  57035573-57035665   c
            21464-21556         JAXUCZ010000003.1  57034685-57034777   c
            21557-21649         JAXUCZ010000003.1  57034075-57034167   c
            21650-21742         JAXUCZ010000003.1  57032379-57032471   c
            21743-21835         JAXUCZ010000003.1  57031976-57032068   c
            21836-21928         JAXUCZ010000003.1  57031554-57031646   c
            21929-22036         JAXUCZ010000003.1  57030627-57030734   c
            22037-22220         JAXUCZ010000003.1  57030113-57030296   c
            22221-22313         JAXUCZ010000003.1  57029772-57029864   c
            22314-22466         JAXUCZ010000003.1  57028655-57028807   c
            22467-22573         JAXUCZ010000003.1  57027984-57028090   c
            22574-23357         JAXUCZ010000003.1  57022822-57023605   c
FEATURES             Location/Qualifiers
     source          1..23357
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q12"
     gene            1..23357
                     /gene="Neb"
                     /note="nebulin"
                     /db_xref="GeneID:311029"
                     /db_xref="RGD:1311134"
     exon            1..79
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            80..161
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            162..226
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     CDS             191..22747
                     /gene="Neb"
                     /codon_start=1
                     /product="nebulin"
                     /protein_id="NP_001406448.1"
                     /db_xref="GeneID:311029"
                     /db_xref="RGD:1311134"
                     /translation="MADEEEYEEVIEYYTEETVYEEVPGETITEIYETTTTRTSDYDQ
                     SETSTPALAQPQPAKPVERKKVIRKKVDTSKFMTPYIEHSQKMQGLFSPNKYKENYEK
                     AKGQPYAITSDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQ
                     QVSKVLYKQNWEDTKDKYLLPPDAPELVQAIKNTAMFSKKLYTEDWEADKGLFYPYND
                     SPELRRVAQAQKALSDIAYKKGLTEQQTQFTSLPDPPDLEFAKKVTNQVSKQKYKEDY
                     EKKVKGKWSETPCFEIATARMNADNLSTRKYQEDFENMKDQIYFMQTETPEYKMNKQA
                     GVAASKVKYKEDYEKNKGKADYNVLPASENPLLRQLKTAGNALSDKLYKENYEKTKAK
                     SINYCETPKYQLDSVLQNFSSDTKYKDSYLKNILGHYVGSFEDPYHTHCMKVTAQNSD
                     KNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLVQ
                     AQVNSKQLSDLNYKAKHESEKFKCHIPPDAPAFIQHRVNAYNLSDNVYKQDWEKSKAK
                     KFDIKVDAIPLLAAKANSKNASDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKN
                     QSDRLYRENYEKTKAKSMNYCETPKYQLDTLLKNFSEKSYKAEYEEDKGKCYFPQTIT
                     QEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDTPVLLQAQLNTKQLSDLNYKAKHEGEK
                     FKCSVPADAPEFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANSKNA
                     SDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPL
                     DMIQVTQAKKSQAIASDVDYKHILHNYSYPPDSINVDLAKKAYALQSDVEYKADYNSW
                     MKGCGWVPFGSLEMEKAKRASEILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRS
                     DIAYKAKGEEILHKYNLPADLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRIDAI
                     PIKAAKAARQAASDIHYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKD
                     YEKTKTKYNTPHDMVDVVAAKKAQDVISNTNYKHSLHHYTYLPDAMDLELSKNMMHIQ
                     SDNAYKEDYNTWMKGIGWIPIGSLDQEKVKKAGDALSEKKYRQHPDTLKFTSIVDSPV
                     MVQAKQNTQQVSDILYKAKGEDVKHKYTLNPDLPQFLQAKCNAYNISDVCYKRDWHDL
                     IAKGNNVLADAIPITAAKSSRNIASDYKYKEAYEKAKGKHVGFRSLQDDPKLVHYMNV
                     AKLQSDREYKKNYENTKTSYHTPGDMVSITAARMAQDVATNVNYKQPIHHYTYLPDSL
                     SLEHTRNANQIQSDNVYKDEYNSFFKGIGWIPIGSLEVEKAKKAGDALNERKYRQHPD
                     TIKFTSVPDSMGMVLAQQNTKQLSDLNYKVEGEKLKHKYTMDPELPQFIQAKVNAINM
                     SDAHYKADWKKTLAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQIGFLSL
                     QDDPKLVHYMNVAKIQSDREYKKGYEASKTRYHTPLDMFSVTAAKKSQEVATNSNYRQ
                     PYHNYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIDSLEVEKAKKAGE
                     ILSERKYRQHPEKLKFTYSMDTMEQALNKSNKLTMDKRLYTEKWNKDKTSIHVMPDTP
                     DILLSRVNQITMSDKLYKAGWEEEKKKGYDLKPDAISIKAAKASRDIASDYKYKQAYE
                     QAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMVSVVAAKK
                     SQEVATNANYRNIIHTYNMLPDAMGFELAKNMMQIQSDNQYKADYADFMKGIGWLPLG
                     SLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNNHLYKQAWEA
                     DKTKIHIMPDIPEIVLAKANAINMSDKLYKLSLEESRKKGYDLRTDAIPIKAAKASRD
                     IASDYKYKHSYEKEKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYEKTKTSYHT
                     PADMLSVTAAKDAQANITNTNYKRLIHKYILLPDAMNIELTRNMNHIQSDNEYKQDYR
                     EWYRGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNAHT
                     MNKHLYTVDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKFYRLGWEEALKKGYDLPVD
                     AISVQLAKTSRDIASDFKYKQGYRKQLGHHIGFLSVQDDPKLVLSMNVAKMQSEREYK
                     KDFEKWKTKYTSPVDMLGVVLAKKCQALVSDVDYKNYLHQWTCLPDQNDVIQAKKVYE
                     LQSENMYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAM
                     DIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIILAKANLINTSDKLYKMGYEE
                     LKKKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIKDDPKMMWSMH
                     VAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDADYRNYLHQWTCLPDQ
                     NDVIHARQAYDLQSDNLYKADLQWLKGIGWITSGSLEDEKNKRATQILSDHVYRQHPD
                     KFKFSSLMDSMPMVLAKNNAITMNHHLYTEAWNNDKTTVHIMPDTPEVMLAKQNKVNY
                     SEKLYKLGLEEAKRKGYDMRLDAIPIKSAKASRDIASDFKYKEGYRKQLGHHIGARAI
                     HDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKN
                     YLHQWTCLPDQNDVIHARQAYDLQSDNMYKSDLQWLRGIGWVPIGSLDVEKCKRATEI
                     LSDKIYRQPPDKFKFTSVTDSLEQVLAKNNAITMNKRLYTEAWDKDKTQIHIMPDTPE
                     IMLARMNKVNYSESLYKLANEEAKKKGYDLRSDAIPIVAAKASRDIASDYKYKDGYRK
                     QLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKYSSPVDMLGVVLAKKC
                     QTLVSDVDYKNYLHQWTCLPDQNDVIHARQAYDLQSDNVYKSDLQWLRGIGWVPIGSL
                     DVVKCKRAAEILSDNVYRQPPNKFKFTSVTDSLEQVLAKSNALNMNKRLYTEAWDKDK
                     IQIHVMPDTPEIVLARQNRINYSESLYKLANEEAKKKGYDLRVDAIPIVAAKASRDIA
                     SDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKYSSPV
                     DMLGVVLAKKCQTLVSDVDYRNYLHQWTCLPDQNDVIHARQAYDLQSDNVYKSDLQWL
                     RGIGWVPIGSLDVVKCKRAAEILSDNVYRQPPNKFKFTSVTDSLEQVLAKNNALNMNK
                     RLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIP
                     IVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKMMWSLHIAKVQSDREYKKEF
                     EKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHLLHEWTCLPDQNDVIQARKAYDLQS
                     DNLYKADLEWMKGIGWVPIGSLEVVKAKRATEILSDNIYRQRPDALKFTSITDSLEQV
                     LAKNNAINMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLSLEEARR
                     QGYDLRVDAIPIRSAKASREIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAK
                     IQSDREYKKDFEKWKTKYSSPVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDV
                     IQARKAYDLQSDAVYKADLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLK
                     FTCITDTPEIVLAKNNAITMSKHLYTEAWDADKASIHVMPDTPEILLAKSNSANISQK
                     LYTKGWDESKMKDYDLREDAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQCVEDD
                     PRIVCAMHAGKIHSDREYKKEFQKWKTKFSSPVDMLGLVLARKCQTLVSDIDYRNYLH
                     NWTCLPDQNDIIQAKKAYELQSDSVYKADLEWLRGIGWIPEGSVEMTRVKGAQDLVNE
                     RLYRTRPEALKFTSIVDTPEVVLAKANSLQMSERLYQEAWNKDKTNISIPLDTPAMLQ
                     AQINALQISNKLYQKDWDEAKQKGYDLRADAIEIKHAKASREIASEYKYKEGYRKQLG
                     HHVGFRSLQDDPKLVWSIHAAKIQSDREYKKAYEKSKGIYNTPLDMMSIVQAKKCQVL
                     VSDVDYRNYLHQWTCLPDQNDVIQAKKAYELQSDNVYKSDLEWMKGIGWLTEGSVDVM
                     RVKNAQNLLNERLYRIKPEAYKFTSIVDTPEVILAKTNALQISEPLYRDAWDKEKANV
                     NVPADTPVMLQSKLNAIQISNKQYQKAWEDVKMTGYDIRADAIGIQHAKASRDIASDY
                     LYKTAYEKQKGHYIGCPSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPGDMV
                     SINAAKEGQALASNVDYRQYLHQWSCFPDQNDVIQARKAYDLQSDAIYKADLEWLRGI
                     GWMPEGSPEVLRVKNAQEILCDSVYRTPVVKLKYTSIVDTPEVVLAKSNAENISIPKY
                     REVWDKDKTSIHIMPDTPEINLARANALNVSHKLYREGWDEVKMSCDVRLDAIPIQAA
                     KASREIASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIAGKIQNEREYRLQWAKWK
                     TKFQSPVDMLSILHSKKCQTLVSDIDYRNYLHQWTCMPDQNDVIQAKKAYELQSDAVY
                     KADLEWLRGIGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQ
                     SSEIRDDIKYRKDWNAIKSKYTLTETPLLHTAQEAARILDQYLYKEGWEKQKATGYIL
                     PPDAVPFVHAHHSSDVQSELKYKAEHVKQRGHYVGVPTMRDDPKLVWFEHAGQIQNDR
                     LYKESYHKSKAKINIPADMVSVVAAKEGQSLVSDIDYRQYLHQWTCHPDQNDVIQAKI
                     AYDLQSDNVYKADLEWLRGIGWIPLDSVDHVRVTKNQEMVNQIKYKKDALDNYPNFTS
                     VVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYMFSPDTPYISHSKDMGKLYSTILYK
                     GAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKEISEFPGV
                     VHCLDFQQMRSALNYRKDYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWT
                     SLPEEPNVIRARNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQY
                     TAASKENLQNYNLVTDTPVYVTALQSGINASEVKYKENYHQIKDKYTTVLETADYDRT
                     KNLKSLYSSNIYKEAWDKVKATSYNLPTSTLSLTHAKNQKHLASRIKYREEYEKFKAL
                     YTLPKSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKINIVPDMVEMVTAKDSQKKV
                     SEIDYRLHLHEWICHPDLQVNSHVRKVTDQISDIVYKDDLTWLKGIGCYVWDTPEILH
                     AKHAYDLRNDIKYKAHVQKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYIHSVRG
                     KVAPTTKTVDLDRALHAYKLQSENLYKKGLRFLPTGYRLPVDTPHFNHTKDTRYMSSY
                     FKYKEAYEHIKANGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPE
                     IRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVLHCRYVGDITSDIKYKEDLQIL
                     KGLGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHL
                     SELVYRASGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTT
                     ALQHAKDVKDMVSEKKYKIQYEKMKDKYTPVADTPILIRAKRAYWNASDLRYKETFQK
                     TKGKYHTVKDALDIVYHRKVTDDISKVKYKENYMSQLGIWSSIPDRPEHFHHRAVTDA
                     VSDVKYKEDLTWLKGIGCYAYDTPDLALAEQNKTLYSKYKYKEVFERTKSNFKYVADC
                     PINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQRKYKSSAK
                     MLLKQGCNEILRPDMLTALYNTHMWSQIKYRKKYEKSKDKFTSVVDTPEHLRTTKVNK
                     QISDILYKLEYNKARPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIKP
                     DAVHIKAAKDAYKVNTNLDYKKQYEANKAYWKWTPDRPDFIQAAKSSLQQSDFEYKLD
                     REFLKGCKLSVTDDKDMVLALRNSLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTV
                     SNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKAVTKHVSDTNYKKKFVKEKGKSN
                     YSIMQEPPEVKHAMDVAKKQSDVAYKKDAKENLHYTTVADRPDIKKATQAAKQASEVE
                     YRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLY
                     KTMKDANNLASEVKYKADLKKLHKPVTDMKESLIMHHVLNTSQLASSYQYKKNYEKSK
                     GHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQS
                     GKEYRKDYEESIKGRNLTGLEVTPALLHVRHATKIASEKEYRKDLEESIRGRGLTEME
                     DTPEMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKY
                     KQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEMQRV
                     RENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIG
                     KTPEMLRVKQTQDHISSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENLGTG
                     IPTTVTPEIERVKRNQENFSSVLYKESLGKGTPTAVTPEMERVKRNQENFSSILYKEN
                     LSKGTPLPVTPEMERVKRNQENFSSILYKENLSKGTPLPVTPEMERVKRNQENFSSVL
                     YKENLGKGIPIPITPEMERVKHNQENFSSVLYKENLGTGIPIPITPEMQRVKLNQENL
                     SSVLYKENMGKGTPLPVTPEMERVKHNQENISSVLYKENVGKATPTPVTPEMQRVKRN
                     QENISSVLYKENLGKATPTPFTPEMERVKRNQENFSSVLYKENMRKATPTPVTPDMER
                     AKRNQENISSVLYSDSFRKQIQGKAAYVLDTPEMRRVRETQRHISTVKYHEDFEKHKG
                     CFTPVVTDPITERVKKNTQDFSDINYRGIQRKVVEIEQKRNDQDQDTITGLRVWRTNP
                     GSVFDYDPAEDNIQSRSLHMVNVQAQRRSRDQSRSASALSISGGEEKSEHSEAADQRL
                     STYSDGGAFFSATSTAYKHVKTTELPQQRSSSVATQQTTLSSIPSHPSTAGKIFRAIY
                     DYMAADADEVSFKDGDAIVNAQAIDEGWMYGTVQRTGRTGMLPANYVEAI"
     exon            227..268
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            269..469
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            470..577
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            578..682
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            683..787
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            788..892
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            893..997
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1102
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1103..1210
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1327
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1328..1432
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1433..1540
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1541..1645
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1744
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1745..1849
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1850..1957
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            1958..2071
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2072..2173
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2174..2278
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2279..2377
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2378..2482
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2483..2590
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2591..2704
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2705..2902
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            2903..3010
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3011..3109
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3110..3214
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3215..3322
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3323..3634
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3635..3841
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3842..3946
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            3947..4054
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            4055..4366
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            4367..4573
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            4574..4678
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            4679..4786
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            4787..5098
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            5099..5305
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            5306..5410
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            5411..5518
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            5519..5830
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            5831..6037
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            6038..6142
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            6143..6250
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            6251..6562
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            6563..6769
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            6770..6874
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            6875..6982
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            6983..7294
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            7295..7498
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            7499..7603
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            7604..7711
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            7712..8023
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            8024..8227
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            8228..8332
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            8333..8440
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            8441..8752
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            8753..8956
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            8957..9061
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            9062..9169
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            9170..9481
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            9482..9685
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            9686..9790
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            9791..9898
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            9899..10210
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            10211..10414
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            10415..10519
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            10520..10627
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            10628..10939
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            10940..11143
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            11144..11248
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            11249..11356
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            11357..11668
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            11669..11872
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            11873..11977
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            11978..12085
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            12086..12397
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            12398..12601
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            12602..12706
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            12707..12814
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            12815..13126
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            13127..13330
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            13331..13435
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            13436..13543
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            13544..13855
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            13856..14059
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14060..14164
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14165..14269
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14270..14581
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14582..14686
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14687..14785
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14786..14887
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14888..14995
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            14996..15307
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15308..15412
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15413..15517
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15518..15622
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15623..15730
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15731..15844
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            15845..16042
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16043..16147
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16148..16252
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16253..16357
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16358..16465
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16466..16579
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16580..16777
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16778..16882
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16883..16987
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            16988..17095
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17096..17200
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17201..17308
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17309..17413
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17414..17518
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17519..17617
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17618..17728
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17729..17833
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17834..17938
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            17939..18043
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18044..18148
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18149..18253
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18254..18358
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18359..18463
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18464..18568
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18569..18673
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18674..18778
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18779..18886
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18887..18991
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            18992..19096
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19097..19201
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19202..19306
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19307..19417
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19418..19528
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19529..19630
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19631..19735
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19736..19846
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19847..19951
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            19952..20056
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20057..20161
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20162..20272
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20273..20383
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20384..20497
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20498..20602
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20603..20707
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20708..20812
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20813..20905
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20906..20998
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            20999..21091
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21092..21184
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21185..21277
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21278..21370
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21371..21463
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21464..21556
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21557..21649
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21650..21742
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21743..21835
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21836..21928
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            21929..22036
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            22037..22220
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            22221..22313
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            22314..22466
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            22467..22573
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
     exon            22574..23357
                     /gene="Neb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcttttgcc tgggcgtctc aggaggggag agcggggaga ggatttgctg ctggccaggg
       61 ttattcacat agctcgaaga cttgaacaag agctacagaa aggaaaaaaa atccgtggaa
      121 gccaatggtt ttccagaaga aaataacccc gttgccttga gtttgtaggt accactactg
      181 ctctggaaaa atggcggatg aggaagagta tgaggaggtg atagagtact acaccgagga
      241 gacggtgtac gaggaggtgc caggagagac aattacagaa atctatgaaa ccacaactac
      301 aaggacatct gactatgacc aatcagaaac ttccacacca gcgctggcac agccacaacc
      361 agcaaaaccg gtggagcgga agaaggtcat tcgaaagaag gtggacacgt ccaagttcat
      421 gaccccctac atagagcaca gtcagaaaat gcagggtctt ttcagcccaa ataaatacaa
      481 agagaactac gagaaagcaa agggacagcc atacgccatc acaagtgata ctccagaact
      541 tcgcagaatc aagaaagtcc aggatcaact cagtgaggtt aagtatcgaa tggatggaga
      601 cgttgctaaa actatctgtc atgtggacga aaaagccaaa gatattgaac atgctaagaa
      661 agtgtcgcag caagtcagca aggttttata caagcagaac tgggaagaca ccaaggataa
      721 gtacctgctt ccccctgatg cccctgaact tgtccaagcc atcaagaaca cagccatgtt
      781 cagtaagaaa ctgtacactg aagactggga agcggacaaa gggttgtttt atccctataa
      841 tgacagtccg gagctgagga gggtcgccca ggcccagaaa gcacttagtg atattgccta
      901 caaaaaagga ctcactgagc agcagactca gttcacatcc ctgcctgatc ctcctgatct
      961 ggaatttgcc aagaaagtaa ccaaccaagt gagcaagcaa aaatataaag aagactatga
     1021 gaagaaagtc aaaggaaaat ggagtgagac accatgcttt gaaattgcaa cagcgagaat
     1081 gaatgcagac aatctcagca caaggaagta tcaggaagac tttgagaaca tgaaagacca
     1141 gatctacttc atgcagactg aaacacctga gtataaaatg aataaacagg ctggggttgc
     1201 cgcgagcaag gtaaaataca aagaagacta tgaaaagaat aaagggaaag cagactacaa
     1261 tgttcttcct gcttcagaga acccactgct taggcagctg aagacggcag gaaacgccct
     1321 cagtgataaa ctatacaagg aaaactatga aaagacaaaa gcgaagagca tcaattactg
     1381 tgagacgccc aagtatcagc tcgactctgt gctacagaac ttcagtagtg acactaagta
     1441 taaagattcc tacctaaaga atatcttggg gcactacgtg ggcagctttg aggacccgta
     1501 tcacacgcac tgtatgaagg ttacagctca aaatagcgat aaaaactaca aagccgagta
     1561 tgaagaggac agaggcaaag gcttcttccc ccagacaatt actcaggaat atgaagcaat
     1621 caagaaactg gaccagtgta aggatcacac ttacaaagtc cacccagata agacaaagtt
     1681 tactcaagtt acagactcgc ctgttctggt acaagcccag gtcaattcca aacagctgag
     1741 tgatctaaat tacaaagcca aacacgaaag tgagaaattc aagtgtcata tacctccgga
     1801 tgctcctgcc tttatccagc acagagtgaa tgcctataac ctgagtgaca atgtctacaa
     1861 gcaagactgg gagaagagca aagctaagaa gttcgacatc aaggtggatg ccatccccct
     1921 gctggcagcc aaagccaaca gcaagaatgc cagtgatgtg atgtacaaga aggactatga
     1981 gaagagcaaa ggcaagatga ttggtgccct cagcatcaat gatgacccca agatgctgca
     2041 ctctctgaag accgccaaga accagagtga cagactatac agagaaaact atgagaagac
     2101 aaaggccaag agcatgaatt actgtgagac ccctaagtat caactggaca cccttctgaa
     2161 gaacttcagt gagaagagtt acaaagcaga atacgaggaa gataaaggga agtgctattt
     2221 ccctcagacg ataacccaag agtacgaagc tatcaagaag ttggaccagt gtaaagatca
     2281 cacctacaaa gtgcaccctg acaagaccaa attcacagcg gtcaccgaca ctcctgtgct
     2341 actgcaagcc cagctcaaca ccaaacagct cagcgatctg aattacaaag caaagcacga
     2401 aggtgagaaa ttcaagtgca gtgtgccagc agatgcaccg gagttcatcc agcacagagt
     2461 caatgcttat aacctgagtg ataatgtcta caagcaagac tgggagaaga gcaaagctaa
     2521 gaagttcgac atcaaggtgg atgccatccc cctgctggca gccaaagcca acagcaagaa
     2581 tgccagtgat gtgatgtaca agaaggacta tgagaagagc aagggcaaga tgattggtgc
     2641 cctcagcatc aatgacgacc ccaagatgct gcactccctg aagaccgcca agaaccagag
     2701 tgatcgcgaa tatcggaaag actatgaaaa gtcaaagacg atctacacag cccctcttga
     2761 catgatccaa gtcacccaag ctaagaaatc tcaggcgatt gccagcgatg tggactacaa
     2821 acacatctta cacaattaca gctacccgcc tgacagcatc aacgtggacc tggccaagaa
     2881 ggcgtacgca ttgcagagtg acgtggagta caaagccgac tacaacagct ggatgaaggg
     2941 ctgtggctgg gtgccctttg ggtctttgga gatggaaaag gcaaagcgag cctcggaaat
     3001 tctgaatgag aaaaaatacc gccagcatcc agatacgctc aagtttacct ccattgaaga
     3061 tgctcccatt acagtgcagt ctaaaattaa ccaggcccag aggagtgata ttgcttacaa
     3121 agccaaaggg gaggaaattc tgcacaagta taacctacca gcagacctgc cgcagttcat
     3181 tcaggctaag gtgaacgcct acaacatcag tgagaatatg tacaaagctg acttgaaaga
     3241 cttaagcaag aagggctatg acctgagaat tgatgccatt cccatcaaag ccgccaaagc
     3301 tgcccgacag gctgcgagtg acattcacta caagaaagat tatgaaaaag ctaaagggaa
     3361 aatggttggc ttccaaagtc tccaagacga tcctaaactg gttcactaca tgaacgtggc
     3421 caagattcag tcagacaggg agtataagaa agactacgaa aagacgaaga ccaagtacaa
     3481 cacgcctcac gacatggtcg atgttgtggc ggctaagaag gcccaggacg tgatcagcaa
     3541 taccaactac aagcactctc tccaccacta cacctacctg ccagacgcca tggacctgga
     3601 gctgtccaag aacatgatgc acatacagag cgataacgcc tacaaggaag actataacac
     3661 ctggatgaag ggcattggct ggattccgat cggcagcctg gaccaagaaa aggttaaaaa
     3721 ggcaggggat gccctgagtg aaaagaaata caggcaacat ccagacacac tcaagttcac
     3781 cagcatcgtg gactcccccg tgatggtgca ggcaaaacag aacacccagc aagtcagtga
     3841 tatcttgtac aaagctaagg gggaagacgt gaagcataag tacaccctga accctgacct
     3901 gccacagttt cttcaggcca agtgcaacgc ttacaacata agcgacgtct gttacaaacg
     3961 ggactggcat gacttgatag ccaaaggcaa caatgtcctg gctgatgcca ttcccatcac
     4021 cgcggccaag tcatcaagaa acatcgccag tgattataaa tacaaggaag cttatgagaa
     4081 ggcgaaggga aagcacgttg gtttcagaag cctccaggac gaccccaagt tggtccatta
     4141 tatgaacgtg gccaagttgc agtcggaccg agaatacaag aaaaactacg agaacaccaa
     4201 aaccagttac catacccctg gggacatggt tagcatcact gctgcaagga tggcccagga
     4261 cgtggccacc aatgtcaact acaagcaacc aatacaccac tacacatacc tgccggattc
     4321 cttgagtctt gagcacacga ggaatgccaa tcaaattcag agcgataatg tgtacaaaga
     4381 cgagtacaac agcttcttca agggcatcgg gtggatcccc atcggctcgc tggaggtgga
     4441 gaaggccaag aaagcaggcg atgctctgaa cgagaggaag taccgacagc acccggacac
     4501 catcaagttc acaagtgtgc ctgactccat gggcatggtt ttggctcagc agaacacaaa
     4561 gcagctaagt gatttgaact acaaggtaga gggagagaaa ctgaagcata aatacacaat
     4621 ggaccctgaa ctgcctcagt tcatccaagc caaagttaac gccatcaaca tgagtgatgc
     4681 tcattacaaa gcagactgga agaaaacact tgccaagggt tacgacttga gaccagatgc
     4741 cattcccatc gttgctgcca aaagttcaag aaacatcgct agtgactgca agtacaagga
     4801 ggcctatgag aaagccaaag gcaagcaaat tggctttctc agtcttcagg atgaccctaa
     4861 gctggttcac tacatgaatg tggccaaaat acaatcagac cgtgaatata agaagggata
     4921 cgaggccagc aagacccggt accacacacc cctagacatg ttcagtgtga ccgctgcaaa
     4981 gaagtctcag gaagttgcaa ccaacagcaa ctacagacag ccctaccaca actacaccct
     5041 cctgcctgat gccttaaatg tggagcactc caggaatgcc atgcagattc agagtgataa
     5101 tctatacaaa tctgacttca ccaactggat gaaaggtatc ggttgggtcc cgatcgactc
     5161 cttggaggtg gagaaggcaa agaaagctgg agagattctg agtgagagga agtatcgcca
     5221 gcacccagag aagctgaagt tcacatactc catggacacc atggagcagg cacttaacaa
     5281 aagcaacaag ttgactatgg ataagaggct gtacactgag aagtggaaca aagacaagac
     5341 cagcattcat gtcatgcctg acactccaga catcctgctc tccagagtaa accagatcac
     5401 catgagtgac aaactataca aggctggctg ggaagaagag aagaagaaag gctatgatct
     5461 caagcctgat gccatctcaa taaaggctgc aaaggcctcc agagacattg ccagtgacta
     5521 caagtacaag caagcctatg aacaagccaa agggaagcac attggcttcc gcagcctgga
     5581 agacgacccc aagctggtgc acttcatgca ggtggccaag atgcagtcag accgggaata
     5641 caagaagggc tatgagaaat ccaagacatc cttccacacc ccagtggaca tggtcagtgt
     5701 ggtggcagcc aagaagtctc aggaagtggc caccaatgcc aactacagga acataatcca
     5761 cacctacaac atgctccctg atgccatggg ctttgagttg gccaagaaca tgatgcagat
     5821 ccagagtgat aatcagtata aggcagacta tgccgacttc atgaagggca ttggatggct
     5881 cccccttggc tccctggaag ccgagaaaaa caagaaagcc atggagatta ttagtgaaaa
     5941 gaaataccgg caacacccag acactttgaa gtactccaca ctgatggact caatgaacat
     6001 ggttttggcc cagaataatg caaaaattat gaataatcat ctctataagc aagcatggga
     6061 agctgacaag acgaaaatcc acatcatgcc cgatatcccc gagatcgttt tggccaaagc
     6121 aaatgcgatc aacatgagtg ataaactcta taaactttcc ctggaagaat ctagaaagaa
     6181 aggctatgac ctcagaacag atgcaattcc tatcaaagct gccaaggcgt cgagagatat
     6241 tgcaagtgat tataaataca agcacagtta tgaaaaggag aaagggaaga tggttggttt
     6301 tcgcagtctg gaagacgatc ccaaattagt ccattccatg caagtggcta agatgcagtc
     6361 tgatcgagag tacaagaaaa actacgagaa gacgaagacc agctaccata ctcctgctga
     6421 catgctgagc gtcacggctg ccaaggacgc gcaagccaac atcaccaaca ccaactacaa
     6481 gcgcctcatt cacaagtaca tcctcctccc agacgcaatg aacatcgagc tgaccaggaa
     6541 tatgaatcac atccagagtg ataacgaata taagcaagac tacagggagt ggtaccgagg
     6601 gcttggctgg agcccagctg gctccctaga ggtggagaag gccaagaaag caactgagta
     6661 tgccagtgat cagaagtacc ggcagcatcc tagcaacttc cagtttaaaa agttgaccga
     6721 ctccatggac atggtgttgg cgaagcagaa tgctcatacc atgaataagc atttatacac
     6781 cgttgactgg aataaagata aaaccaagat tcatgtgatg cctgatacac cagatatttt
     6841 gcaagccaag cagaatcaga cactttacag tcagaaattc tacagacttg gttgggaaga
     6901 ggctctgaag aaaggctacg atctccctgt tgatgcaatt tctgtccagc tggccaagac
     6961 atcaagggac attgctagtg actttaaata taaacaaggc taccggaaac aactgggaca
     7021 ccatattgga ttcctgagcg tgcaagatga cccaaagctt gtgctatcga tgaatgtagc
     7081 caaaatgcaa agtgaaagag agtacaagaa agactttgag aagtggaaga ccaaatacac
     7141 cagccctgtg gacatgctgg gtgtggtgtt ggccaagaag tgccaggcct tggtcagtga
     7201 tgtggactac aagaactacc tacaccagtg gacgtgcttg cctgaccaga atgacgtcat
     7261 ccaagctaaa aaggtctatg agctgcaaag tgagaatatg tataagtctg atctagagtg
     7321 gctgagaggc ataggatgga gtcccctggg ttctttggaa gcagaaaaga acaagcgggc
     7381 ttcagaaatc atcagtgaaa agaaataccg ccaacctcca gacagaaata agtttaccag
     7441 cattcctgat gccatggaca tagttctggc taaaacaaat gccaaaaaca ggagcgatag
     7501 actttacaga gaagcgtggg acaaggacaa gactcagatc cacatcatgc ctgacactcc
     7561 tgacatcatt ctggctaagg caaacttaat caacacaagt gataaactct acaaaatggg
     7621 ttatgaggaa ctgaagaaaa aaggatatga tcttcctgtc gatgccattc ccatcaaagc
     7681 agctaaagcg tcccgggaaa ttgccagtga atacaaatac aaggaaggct tccgaaagca
     7741 actgggccac cacattggtg ctcggaacat caaagatgac cccaagatga tgtggtccat
     7801 gcacgtggcc aagatccaga gtgacaggga gtacaagaag gactttgaga agtggaagac
     7861 caagttcagc agcccagtgg atatgctggg ggtggtgctg gccaagaagt gccagacctt
     7921 ggtcagtgat gctgactaca ggaactacct acaccagtgg acgtgcttgc ccgaccagaa
     7981 tgatgtcatc cacgctcggc aggcctatga tctccagagc gataatttgt acaaggctga
     8041 tcttcagtgg cttaaaggca ttggctggat tacttctggt tctctcgagg atgagaaaaa
     8101 caaacgagcc actcagatcc tgagcgacca tgtctaccgt cagcacccgg ataaattcaa
     8161 gttttccagt cttatggact ccatgccaat ggtgctggca aaaaataatg ctataaccat
     8221 gaaccaccac ctctatacag aagcttggaa taatgataaa accactgtcc acattatgcc
     8281 ggacacccct gaagttatgt tggctaaaca gaacaaagta aattacagcg agaaattata
     8341 taagcttggc ctggaagaag ccaagaggaa aggctatgac atgcggcttg atgccattcc
     8401 tatcaagtca gccaaggcct ccagagacat cgccagtgac ttcaagtaca aggaaggcta
     8461 ccgtaagcag ctgggccacc acatcggtgc tcgcgctata catgatgacc ccaagatgat
     8521 gtggtccatg cacgtggcca agatccagag tgacagggag tataagaagg actttgagaa
     8581 gtggaagacc aagttcagca gcccagtgga catgctgggg gtggtgctgg ctaagaagtg
     8641 ccagaccttg gtcagtgatg tggactataa gaactaccta caccagtgga cgtgcttgcc
     8701 cgaccagaat gatgtcatcc atgctcggca ggcctatgat ctccagagcg ataacatgta
     8761 caagtctgat ctccagtggc tgagaggcat cggctgggta cccattggct ctctggatgt
     8821 ggaaaaatgc aaacgggcca cagaaatctt gagtgacaaa atctaccgtc agcccccgga
     8881 caaattcaag tttaccagtg tgactgattc tctggagcaa gtgttggcca agaacaatgc
     8941 cattactatg aacaagcgtt tgtacacgga agcctgggac aaagacaaga cccagatcca
     9001 catcatgcca gatacaccag aaatcatgtt ggcgagaatg aataaagtca actacagcga
     9061 gagtctgtat aaactggcca atgaagaagc gaagaagaaa ggctatgact tgcgaagcga
     9121 tgccatcccc atagtggcgg ccaaggcctc cagagacatc gcgagtgact acaaatacaa
     9181 agatggctac cgtaagcagc tgggtcacca catcggtgcc cgcaacatcg aagatgaccc
     9241 caagatgatg tggtccatgc acgtggccaa gatccagagt gacagggagt acaagaagga
     9301 ctttgagaag tggaagacca agtacagcag cccagtggac atgctggggg tggtgctggc
     9361 caagaagtgc cagaccttgg tcagcgatgt ggactataag aactacctac accaatggac
     9421 gtgcttacct gaccagaatg atgtcatcca tgctcggcag gcctatgatc tccagagtga
     9481 taatgtgtac aagtcagatc tccagtggct gagaggcatc ggctgggtcc ccatcgggtc
     9541 tctggatgtg gtcaagtgca agagggccgc agagatcctg agtgacaacg tctaccgcca
     9601 gcctccaaac aagttcaagt tcaccagtgt gactgactct ctggagcagg tgctggccaa
     9661 gagcaatgcc ctcaacatga acaagcgatt atacacagag gcctgggaca aagacaagat
     9721 tcaaattcac gtgatgcctg atacaccaga gattgtgctg gcaaggcaga acaggatcaa
     9781 ctacagcgag agcctgtata aactggccaa tgaagaagca aagaagaaag gctatgacct
     9841 gcgtgtcgat gctatcccca tcgtggcggc caaggcctcc agagatattg ccagtgatta
     9901 caaatacaaa gatggctacc gtaagcagct gggtcaccac atcggtgccc gcaacatcga
     9961 agatgacccc aagatgatgt ggtccatgca cgtggccaag atccagagtg acagggagta
    10021 caagaaggac tttgagaagt ggaagaccaa gtacagcagc ccagtggaca tgctgggggt
    10081 ggtgctggcc aagaagtgcc agaccttggt cagtgatgtg gactacagga actacctaca
    10141 ccagtggacc tgcttgcctg accagaatga tgtcatccat gctcggcagg cctatgatct
    10201 ccagagcgat aatgtgtaca agtcagatct ccagtggcta agaggcatcg gctgggtccc
    10261 catcgggtct ctggatgtgg tcaagtgcaa gagggccgca gagatcctga gtgacaacgt
    10321 ctaccgccag cctccaaaca agttcaagtt caccagtgtg actgactctc tggagcaggt
    10381 gctggccaag aacaatgccc tcaacatgaa caagcgcttg tacacagaag cctgggataa
    10441 agacaagacc cagatccaca ttatgcctga tacacctgaa attatgttgg ccagacaaaa
    10501 taaaataaac tacagtgaga gcctttatcg ccaggccatg gaagaagcta agaaggaagg
    10561 ctatgacttg agaagcgatg ccattcccat cgtggctgcc aaggcttccc gggacattgc
    10621 tagtgattac aaatacaaag aagcctatcg gaagcagttg ggtcaccaca ttggtgccag
    10681 agccgtacac gatgatccca agatgatgtg gtccctccac attgccaaag tacagagtga
    10741 ccgtgagtat aagaaagaat ttgagaagta caagacacgg tacagcagcc cggtggacat
    10801 gcttggtatt gttctggcca agaaatgcca aaccttggtc agtgatgtgg actacaaaca
    10861 cctactgcat gaatggacct gcctcccaga ccagaatgat gtcatacagg cccggaaagc
    10921 atatgacctc cagagtgata atctgtataa ggcagacctt gaatggatga aaggcattgg
    10981 ctgggttccc attggctcct tggaagttgt caaagccaag agggccacag agatactgag
    11041 cgacaacatc taccgccagc gtccggacgc actgaagttc accagtataa ctgactcgct
    11101 ggagcaggtg ctggcaaaga acaatgcaat aaacatgaac aagcgcttgt acactgaagc
    11161 ctgggacaac gacaagaaaa ccattcatgt catgccggac acaccagaaa tcatgctggc
    11221 caaactcaac aggataaact acagcgacaa actctacaaa ctgtctctgg aagaggccag
    11281 gaggcaaggc tacgatttgc gtgtggacgc cattcccatc cgatcagcca aggcatcaag
    11341 agagattgct agtgattaca agtacaagga aggctaccgc aaacagctgg gccaccacat
    11401 tggggcccgg aacatcaaag atgaccccaa gatgatgtgg tccatacacg tggccaagat
    11461 ccagagtgac agggagtaca agaaagactt tgagaagtgg aagaccaagt acagcagccc
    11521 agtggacatg ctgggggtgg tgctggccaa gaagtgccag atccttgtaa gcgacataga
    11581 ctataagcat cctctccacg agtggacatg cctgcctgac cagaacgatg tcattcaggc
    11641 acggaaggct tatgatctcc agagcgatgc tgtgtacaag gctgatcttg agtggctgag
    11701 aggcattggc tgggttccca ttggctctgt agaggtcgag aaggtgaaga gagcagggga
    11761 aatcctgagt gacaggaaat atcgccagcc tgcagaccag ctcaagttca cctgtattac
    11821 agacacccct gaaatcgtcc tggcaaagaa taatgccatc accatgagca agcatttata
    11881 cacagaggct tgggatgctg acaaagcctc catccatgtc atgccagaca cccctgaaat
    11941 cctgctggcc aagagcaatt ctgccaatat cagccaaaaa ctatatacca agggatggga
    12001 cgaatcaaag atgaaggact atgacctgag agaggatgct atttccatca aaagtgccaa
    12061 ggcctccagg gacattgcca gtgattacaa atataaggaa gcctatgaaa aacagaaggg
    12121 ccaccacatt ggagcccagt gtgttgaaga cgatcccagg attgtgtgcg ccatgcatgc
    12181 agggaagatt cacagtgaca gggagtacaa gaaggaattc cagaaatgga agaccaagtt
    12241 cagcagcccg gtggacatgc tcggcttggt gctggccagg aagtgccaga ctctggtcag
    12301 cgacattgac tacaggaact accttcataa ctggacttgc ctgcctgacc agaacgacat
    12361 tattcaagca aagaaggcct atgaactgca gagtgatagt gtgtataaag cagatctgga
    12421 gtggctgcgt ggcattggct ggataccaga aggctccgtg gaaatgacca gagtgaaggg
    12481 cgcccaagac cttgtgaatg agagattgta taggacacgg ccagaagcct tgaagttcac
    12541 ctccattgtg gacactccag aagttgtcct ggcaaaagcc aattctctgc aaatgagtga
    12601 gaggctgtac caggaagcct ggaataaaga taaaaccaac atcagcattc ccttggacac
    12661 tccagcgatg ctgcaggccc agatcaatgc cttgcagatt agcaacaaac tctaccaaaa
    12721 agactgggat gaagccaagc agaaaggcta cgacttaaga gcagacgcca ttgaaatcaa
    12781 gcacgccaaa gcctccaggg agatcgccag tgagtacaaa tacaaagaag gttaccgaaa
    12841 gcagctaggc catcacgtgg gtttccgtag cctgcaggat gaccccaagt tggtatggtc
    12901 tatacacgct gctaagatcc agagtgacag agagtacaag aaggcctacg agaagtcgaa
    12961 aggcatttac aacacgccct tggacatgat gtcaatcgtt caagccaaga aatgccaagt
    13021 cctggtcagc gacgttgact atcgcaatta cctgcaccag tggacgtgcc tgccggatca
    13081 gaacgacgtg atccaggcta agaaagccta cgagctgcag agcgataatg tgtacaagtc
    13141 agacctggaa tggatgaagg gtatcggatg gttgacggag ggttctgtgg atgtgatgag
    13201 agtgaagaat gctcagaatc ttttgaatga aaggttgtat cgcataaagc ctgaggccta
    13261 caagttcacg agcatcgtcg acaccccaga ggtgatcctg gcgaagacga atgccctgca
    13321 aatcagtgag ccattgtatc gtgatgcctg ggacaaagag aaggccaacg tgaatgtgcc
    13381 agctgacacc cctgtgatgt tgcagtccaa actgaatgcc atccagatta gcaataaaca
    13441 gtatcagaag gcttgggaag acgtcaagat gacaggttat gacatccgtg cagatgccat
    13501 tgggatccag catgccaagg cctctcggga tattgccagc gactatctgt acaagactgc
    13561 ttatgagaag cagaaaggcc attacattgg atgtcccagt gccaaggaag acccaaaact
    13621 ggtttgggca gcaaacgtgt tgaagatgca gaatgacagg ctgtacaaaa aagcctacaa
    13681 tgatcacaag gccaagatct ccatccccgg ggacatggtg tccatcaacg ctgccaagga
    13741 gggccaggca ttggcaagca acgtggacta tcggcagtac ctgcaccagt ggtcctgctt
    13801 tcctgaccag aatgacgtga tccaagccag gaaagcctac gacctgcaga gtgatgccat
    13861 ctacaaggct gacttggagt ggctgcgtgg cattggctgg atgccagaag gctctcctga
    13921 agtactgaga gtcaaaaatg cccaagagat cctctgcgac agtgtctatc ggacccccgt
    13981 ggtgaagctc aagtacacga gtattgtgga tacaccggaa gttgtccttg ctaagtcaaa
    14041 tgctgaaaat attagtattc caaaatacag agaagtttgg gacaaagata aaacttccat
    14101 ccacataatg ccagacacgc ctgaaattaa tctcgctcga gcaaacgctc ttaatgtgag
    14161 ccataaactc taccgtgagg ggtgggatga agtcaagatg agctgtgatg tccggctgga
    14221 tgccatcccc atccaggctg ccaaggcctc cagggagatt gctagtgatt ataaatacaa
    14281 gcttgaccac gagaagcaga agggacacta cgtgggcacc ctcacagcca gggatgacaa
    14341 caagatccgg tgggccctca tcgctggcaa gatccagaat gaaagggagt acaggctgca
    14401 gtgggccaaa tggaagacca agttccagag ccccgtggac atgctgtcca tcctgcattc
    14461 caagaagtgc cagacgctgg tcagcgacat tgactatcgc aattacctac accagtggac
    14521 ctgcatgcct gaccagaacg acgtgattca ggccaagaaa gcctacgagc tacagagcga
    14581 cgctgtttac aaggctgact tggagtggtt acgtggcatt gggtggatgc caaacgattc
    14641 tgtctctgtc aatcacgcca aacacgctgc tgatatcttc agcgagaaaa aataccgcac
    14701 gaaaatagaa actctcaact tcactcctgt ggatgacaga gtggattacg tgacagcgaa
    14761 acaaagcagt gagatccgag atgacattaa atatcggaaa gattggaacg ccatcaaatc
    14821 aaagtatacc cttacagaaa ccccactgct gcacactgcc caggaggctg cccggatcct
    14881 ggaccagtac ctctacaagg aaggttggga aaaacagaaa gccacgggct acatcctgcc
    14941 acctgatgct gtcccatttg ttcatgccca ccattccagt gacgttcaga gtgagctaaa
    15001 gtacaaggct gaacacgtta agcagagagg ccactacgtc ggggttccca caatgagaga
    15061 cgaccccaag ctggtttggt ttgagcacgc aggccagatt caaaatgaca gactctacaa
    15121 ggagagctac cacaagtcaa aggccaaaat caatatacct gctgacatgg tgtcggttgt
    15181 ggctgccaag gaagggcaga gccttgtcag tgacatcgat taccgtcagt acctacacca
    15241 atggacctgc caccccgacc aaaatgatgt tattcaagca aaaattgcct atgatcttca
    15301 gagtgacaat gtctacaaag ctgacctgga atggctccga ggaattggct ggatccctct
    15361 ggattctgtg gaccatgtga gggttacaaa gaaccaggaa atggtgaatc agataaaata
    15421 caagaaagac gctcttgaca actatcccaa cttcacaagt gtggtggacc ctccagagat
    15481 tgtcttagcc aagatcaact cagtcaatca aagtgatgta aaatataaag aaacattcaa
    15541 taaagccaag ggcaagtaca tgttttctcc agacacaccg tacatctccc actccaaaga
    15601 catggggaaa ctctacagta ctatactata caagggagca tgggagggaa ccaaggccta
    15661 cggctatacc ctggatgagc gctatattcc gattgttgga gccaagcatg ctgacctggt
    15721 gaacagtgag cttaaataca aggaaaccta tgagaaacag aaaggtcact acctggctgg
    15781 aaaagaaata agcgagttcc ctggtgtggt ccactgcttg gatttccagc agatgcggag
    15841 tgcgttgaac tacagaaaag actacgagga caccaaagca aacgtgcata ttcccaacga
    15901 catgatgaac cacgtgctgg cgaagaggtg ccagtacatc ctcagcgacc tggagtaccg
    15961 acactacttt caccagtgga cgtcacttcc tgaggagccc aatgttatcc gtgcccgaaa
    16021 cgcccaggag atcttaagtg ataatgtata taaagacgac ttgaactggc tgaagggcat
    16081 cggctgctat gtttgggata caccccagat cctccatgcc aagaaatcat atgacctcca
    16141 gagtcagcta caatacacag cagcaagtaa agaaaatctg cagaactata acctggtcac
    16201 agacacacca gtttacgtga ctgctcttca gagtggcatc aatgccagtg aggtgaaata
    16261 taaagaaaat taccatcaga ttaaggacaa gtataccaca gtgctggaga cagccgacta
    16321 tgacagaacc aagaacttga agagcctgta cagcagtaac atatacaaag aggcctggga
    16381 taaggtgaaa gccaccagct ataacctgcc aaccagcacc ttgtccttga cacatgccaa
    16441 gaaccagaag cacctggcca gccgtatcaa ataccgagaa gaatatgaga agttcaaagc
    16501 cctttacacg ttaccgaaaa gtgttgacga cgatccgaac acagcacggt gtctccgagt
    16561 gggcaagctt aatatcgatc gcttgtacag gtcagtgtac gagaagaaca agatgaaaat
    16621 caacatcgtg cccgacatgg tggagatggt gacggccaag gactctcaga agaaagtcag
    16681 cgagatcgac taccgcctgc accttcatga gtggatttgc caccctgact tacaagtcaa
    16741 cagtcacgtc agaaaagtga cagaccagat cagcgacatt gtgtacaagg atgacctcac
    16801 ctggctgaag ggcattggtt gctacgtctg ggacactcct gaaattctcc atgcaaaaca
    16861 tgcttatgat ctacgcaacg atatcaagta taaagctcat gtgcagaaga cgaggaatga
    16921 ctacaagctg gtgactgaca caccggtgta cgtccaggcc gtcaagagtg ggaagcagct
    16981 cagtgatgct gtctaccact atgactacat acacagtgtc agaggcaaag tggccccaac
    17041 taccaagact gtggatctgg accgggccct ccacgcatat aagcttcaga gtgagaatct
    17101 gtacaagaaa ggcctgcgtt tcctgcctac tgggtacagg ctccccgttg atacccctca
    17161 tttcaaccac accaaggaca cccgctacat gagcagctat tttaagtaca aagaagccta
    17221 tgaacacatc aaggcaaatg gctacacgct tggacccaag gacgtcccat ttgtccatgt
    17281 ccggagagtc aacaacgtta ctagtgagag actatatcga gaactgtatc ataaactgaa
    17341 agacaagata catacaactc cagacacacc tgaaatccgc caagtcaaga agacacaaga
    17401 ggctgtcagt gagttgatct acaaatcaga cttcttcaag atgcagggac acatgatctc
    17461 gctgccatac acaccccaag tgttgcactg tcgctacgtg ggagacatca ccagtgacat
    17521 taaatacaaa gaggacctgc agatcttgaa gggacttggc tgcttcctgt atgacacccc
    17581 tgacatggtc cgctcccggc acctaaggaa actctggtcg aattacctgt acacggataa
    17641 agccaggaag atgcgagaca aatacaaagt ggtgcttgat accccagagt acagaaaagt
    17701 gcaggaactg aagacacatc tgagtgagct ggtttacaga gcctcaggca agaagcagaa
    17761 gtccatcttc acttcagttc ccgatacccc tgaccttcta agagccaagc gaggacagaa
    17821 gcttcagagt cagtatctct atgttgagct tgccactaaa gagagacccc accaccacgc
    17881 tgggaatcag accacagcct tgcaacacgc taaagatgtg aaggacatgg tcagcgagaa
    17941 aaagtacaag attcagtatg aaaagatgaa ggacaagtat acaccagttg cagacacgcc
    18001 aatcctcatc agagccaaga gagcttactg gaacgccagc gatcttcgct acaaagaaac
    18061 atttcaaaag acgaaaggga aatatcacac tgtgaaggac gccctggaca tcgtgtatca
    18121 tcgcaaagtc accgacgaca tcagtaaagt gaaatacaag gaaaactaca tgagccagct
    18181 gggaatctgg agttccattc ctgatcgccc tgaacatttc caccaccggg cagtcactga
    18241 tgccgtcagc gatgtgaaat ataaagaaga tttgacctgg cttaaaggca ttggctgcta
    18301 tgcctatgat acccctgact tggcattagc tgaacagaac aagactctct acagcaagta
    18361 taagtataaa gaagtatttg aaagaacaaa gtcaaacttc aagtatgttg ctgactgtcc
    18421 aattaacagg catttcaagt acgcaactca gttgatgaac gagaaaaaat acagagctga
    18481 ttatgagcag cggaaagata aataccacct ggtagtcgat gaacctagac atctgctggc
    18541 taagacggca ggcgaccaga tcagccagag aaaatataag tctagtgcca agatgcttct
    18601 gaaacaaggc tgtaatgaga tcctgcgtcc agatatgttg actgctctct acaatacaca
    18661 catgtggagc cagatcaaat acaggaaaaa gtatgagaag tcaaaggaca aattcacctc
    18721 cgttgtggac accccggagc acctgcgcac cacaaaagtc aacaagcaaa tcagtgacat
    18781 actttataag ctggagtaca acaaagccag acccagaggc tacaccacca tccatgacac
    18841 acccatgctg ctccatgtcc gaaaagtgaa ggatgaagtc agtgatctga aatataagga
    18901 agtttaccaa aggaataaat ctaactgcac catcaagccg gatgctgttc acatcaaggc
    18961 agcaaaagat gcctacaaag tcaacacgaa tctggactac aagaagcagt atgaggccaa
    19021 taaagcctac tggaagtgga cacccgaccg cccagacttc atccaggccg ccaagtcatc
    19081 cctgcagcaa agcgattttg aatacaagct ggaccgagag tttctcaagg gctgcaagct
    19141 ttctgtcact gatgataagg acatggtgtt ggccctcagg aactccttaa tagaaagcga
    19201 tctgaaatac aaagagaaac acgtaaagga aaggggaacc tgtcatgctg tgcctgacac
    19261 cccacagatc ctcttggcaa agactgtcag caatctggtg tctgagaaca agtacaagga
    19321 ccatgtcaag aagcacctgg cccagggctc atacacaaca ctgccagaga ccagggatac
    19381 agttcatgtc aaggcagtga ccaagcacgt cagtgataca aactacaaga agaagttcgt
    19441 caaagagaaa gggaagtcca actactccat catgcaagag cctccagagg tgaagcatgc
    19501 gatggacgtg gccaagaagc agagtgatgt tgcttataaa aaagatgcca aagagaatct
    19561 gcattacacc acagtggccg acaggccaga catcaagaag gccacccagg cagccaaaca
    19621 ggccagtgag gtggagtaca gagccaagca ccgcaaggaa ggcagccacg ggttaagcat
    19681 gcttggccgc ccagacattg agatggccaa gaaggcggcc aagctgagca gccaggttaa
    19741 ataccgagaa aactttgaca aggagaaagg caaaacaccc aaatacaacc caaaagacag
    19801 ccagctctac aaaactatga aagatgccaa caaccttgca agtgaggtca aatacaaggc
    19861 tgacctgaag aaactccaca aacccgtgac tgacatgaag gaatccctga taatgcatca
    19921 cgtcctgaat acaagccagc tcgccagctc ttaccagtac aagaagaact atgagaagag
    19981 caaaggccac taccacacga tacccgataa cctggaacag ctacacctca aagaagccac
    20041 agagctgcag agtatcgtga aatacaaaga aaaatatgaa aaagaacgag gcaagcccat
    20101 gctggacttt gagactccaa catacatcac tgccaaagag tctcagcaga tgcagagtgg
    20161 gaaagaatat aggaaagatt acgaagagtc cattaaaggc agaaacctga cgggcctgga
    20221 ggtcacgcca gcattgttac atgtcagaca tgcaaccaaa atagcgagcg agaaagagta
    20281 taggaaagac ctagaagaaa gcatccgggg cagaggtctc actgaaatgg aagatactcc
    20341 cgaaatgctg agagccaaga atgcaactca aatcctcaat gagaaagaat ataagcgaga
    20401 cctagagctg gaagtcaaag gaagaggcct gaatgccatg gccaacgaga ctccagattt
    20461 tatgcgggcc aggaatgcta ccgacattgc cagccagatt aagtacaagc aatcggcaga
    20521 aatggaaaag gccaatttca cttctgttgt tgatacccca gaaattatcc atgctcagca
    20581 ggtcaagaac ctctctagcc agaaaaagta caaggaagat gcagagaagt ccatgtcata
    20641 ttacgagact gtcttggata ccccagagat gcaaagagtc cgtgagaacc agaagaactt
    20701 cagcctcctt caataccagt gtgaccttaa aaacagtaag gggaaaatta cagtggtcca
    20761 agacacgcca gaaatactgc gtgttaaaga aaaccaaaag aatttcagct cggttttata
    20821 taaagaggat gtgtccccgg gaacagcaat cggaaagact ccggagatgc tcagggtgaa
    20881 gcaaactcag gaccacatta gctcggtcaa gtataaagaa gcaattggac aaggaactcc
    20941 catccctgac ctgcccgaag tgaagcgcgt caaggagacc cagaagcaca ttagctcggt
    21001 tatgtacaaa gaaaacctgg gaacaggcat cccaaccact gtcaccccag agattgagag
    21061 agtcaaacgc aatcaagaga actttagctc ggttttgtac aaagaaagtt tgggaaaagg
    21121 aacccctaca gctgtcactc cagagatgga gagagtcaag cgcaatcaag agaactttag
    21181 ctcgatattg tacaaagaga acctgagcaa ggggaccccc ttacctgtca ctccagagat
    21241 ggagagagtc aagcgcaatc aagagaactt tagctcgata ttgtacaaag agaacctgag
    21301 caaggggacc cccttacctg tcactccaga gatggagaga gtcaagcgca atcaagaaaa
    21361 ctttagctcg gtgttgtata aagagaacct tggaaaaggg attccgatcc ccatcactcc
    21421 agagatggag agagtcaaac acaatcaaga aaactttagt tcggtgctat acaaagaaaa
    21481 cctggggaca ggaattccca tccccatcac tccagagatg cagagagtaa aactcaatca
    21541 agaaaacctt agctcggtgc tatataaaga aaacatgggc aagggaaccc ctttacctgt
    21601 cactccagag atggagagag tcaaacacaa tcaagaaaat attagctcgg ttttgtacaa
    21661 agaaaatgtg ggtaaagcca ccccaacccc tgtcactcca gagatgcaga gagtcaaacg
    21721 caatcaagaa aacattagct cggtgctata caaagagaac ctggggaaag caacccccac
    21781 acccttcact cctgagatgg aaagagtcaa acgcaatcaa gaaaacttta gctcggtatt
    21841 gtacaaagag aacatgagaa aagcaacacc aacacctgtc actccagaca tggagagagc
    21901 caaacgcaac caagaaaata ttagctcggt tctttactcc gatagcttcc ggaaacaaat
    21961 acaaggtaaa gctgcctatg tgctagatac accagagatg aggcgggtta gggaaaccca
    22021 acggcacatc tcaacagtga aatatcatga agactttgag aaacacaaag gctgtttcac
    22081 accggtggtg acagacccta tcactgaacg agtaaagaaa aacacacagg acttcagtga
    22141 cattaactac cgaggtattc agagaaaagt ggtggaaata gaacagaagc ggaatgacca
    22201 ggatcaagat accattacag gcctgcgtgt ctggcggact aaccctggtt cagtttttga
    22261 ttatgacccg gcagaagata acatccagtc ccgaagtttg cacatggtca atgtccaagc
    22321 tcaacgccgg agccgggacc agtccagatc tgccagtgca ctgagcatca gtgggggtga
    22381 ggagaagtct gagcactcgg aggccgcaga ccagcgcctt tccacataca gtgacggagg
    22441 tgccttcttc tctgcaacct caacagctta caaacatgtg aaaaccaccg agctcccaca
    22501 gcagcgatca tcctcagttg ccacccagca gacaacactg tcttccatcc cgtcacaccc
    22561 atctactgcc ggaaaaatct tccgtgccat atatgactat atggctgcag atgcggatga
    22621 agtgtccttt aaagatggag atgctatagt gaatgctcag gcgattgatg aaggctggat
    22681 gtatggcact gtgcagagga ccggcaggac cggcatgctc cctgccaact atgtggaagc
    22741 tatttaagca cttcaagatc tccatcagtc tgcagtgtct gcacctctgc aggcaacatc
    22801 tcagtggaga ctccaatgta cccatggccc tcaagctctc taatgttttc acctgtatca
    22861 gaatcacttc atggtttctc ttctacggaa accacggtta ttctccatgg aacccaacat
    22921 taattcagtt cttaaactag acttacaact tcattttttt tttctggatt gatacatgaa
    22981 actagagaca gtaaacatgt aaaagcttat ttccaaaaga agcttttaca tcatgaaacc
    23041 tgttttaaag taagctgaaa ttcacaatag aatttttaaa cgcttctgta gtataatgta
    23101 accaaaccag tccttcccaa ttataaaaac attgacctta ttctgaacac ccaaacagta
    23161 aaagaaaaac agaagggaga accacctttc tcttgtttac taagtgcaaa agcttgtgtt
    23221 tctaatttca tttctgtaag ctataaagat gacagtcaat ataaaatgtt gagaaactag
    23281 aaactaataa aacctatagt accaaaataa actgtacacg gctaaacttt aataaagtct
    23341 gagtttaagt tacctaa
//
