LOCUS       NM_001006972            1506 bp    mRNA    linear   ROD 20-FEB-2025
DEFINITION  Rattus norvegicus NADH:ubiquinone oxidoreductase core subunit V1
            (Ndufv1), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001006972 XM_215176
VERSION     NM_001006972.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1506)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1506)
  AUTHORS   Moutaoufik,M.T., Malty,R., Amin,S., Zhang,Q., Phanse,S.,
            Gagarinova,A., Zilocchi,M., Hoell,L., Minic,Z., Gagarinova,M.,
            Aoki,H., Stockwell,J., Jessulat,M., Goebels,F., Broderick,K.,
            Scott,N.E., Vlasblom,J., Musso,G., Prasad,B., Lamantea,E.,
            Garavaglia,B., Rajput,A., Murayama,K., Okazaki,Y., Foster,L.J.,
            Bader,G.D., Cayabyab,F.S. and Babu,M.
  TITLE     Rewiring of the Human Mitochondrial Interactome during Neuronal
            Reprogramming Reveals Regulators of the Respirasome and
            Neurogenesis
  JOURNAL   iScience 19, 1114-1132 (2019)
   PUBMED   31536960
REFERENCE   3  (bases 1 to 1506)
  AUTHORS   Guo,R., Zong,S., Wu,M., Gu,J. and Yang,M.
  TITLE     Architecture of Human Mitochondrial Respiratory Megacomplex
            I2III2IV2
  JOURNAL   Cell 170 (6), 1247-1257 (2017)
   PUBMED   28844695
REFERENCE   4  (bases 1 to 1506)
  AUTHORS   Wang,Z., Fan,M., Candas,D., Zhang,T.Q., Qin,L., Eldridge,A.,
            Wachsmann-Hogiu,S., Ahmed,K.M., Chromy,B.A., Nantajit,D., Duru,N.,
            He,F., Chen,M., Finkel,T., Weinstein,L.S. and Li,J.J.
  TITLE     Cyclin B1/Cdk1 coordinates mitochondrial respiration for cell-cycle
            G2/M progression
  JOURNAL   Dev Cell 29 (2), 217-232 (2014)
   PUBMED   24746669
REFERENCE   5  (bases 1 to 1506)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   6  (bases 1 to 1506)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   7  (bases 1 to 1506)
  AUTHORS   Murray,J., Zhang,B., Taylor,S.W., Oglesbee,D., Fahy,E.,
            Marusich,M.F., Ghosh,S.S. and Capaldi,R.A.
  TITLE     The subunit composition of the human NADH dehydrogenase obtained by
            rapid one-step immunopurification
  JOURNAL   J Biol Chem 278 (16), 13619-13622 (2003)
   PUBMED   12611891
REFERENCE   8  (bases 1 to 1506)
  AUTHORS   Triepels,R.H., Hanson,B.J., van den Heuvel,L.P., Sundell,L.,
            Marusich,M.F., Smeitink,J.A. and Capaldi,R.A.
  TITLE     Human complex I defects can be resolved by monoclonal antibody
            analysis into distinct subunit assembly patterns
  JOURNAL   J Biol Chem 276 (12), 8892-8897 (2001)
   PUBMED   11112787
REFERENCE   9  (bases 1 to 1506)
  AUTHORS   Ali,S.T., Duncan,A.M., Schappert,K., Heng,H.H., Tsui,L.C., Chow,W.
            and Robinson,B.H.
  TITLE     Chromosomal localization of the human gene encoding the 51-kDa
            subunit of mitochondrial complex I (NDUFV1) to 11q13
  JOURNAL   Genomics 18 (2), 435-439 (1993)
   PUBMED   8288251
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083709.1.
            
            On Nov 22, 2004 this sequence version replaced XM_215176.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083709.1, FQ212198.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1506
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1506
                     /gene="Ndufv1"
                     /note="NADH:ubiquinone oxidoreductase core subunit V1"
                     /db_xref="GeneID:293655"
                     /db_xref="RGD:1359247"
     exon            1..84
                     /gene="Ndufv1"
                     /inference="alignment:Splign:2.1.0"
     CDS             13..1407
                     /gene="Ndufv1"
                     /EC_number="7.1.1.2"
                     /note="NADH dehydrogenase (ubiquinone) flavoprotein 1,
                     51kDa"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] flavoprotein 1,
                     mitochondrial"
                     /protein_id="NP_001006973.1"
                     /db_xref="GeneID:293655"
                     /db_xref="RGD:1359247"
                     /translation="MLAARHFLGGSVPVRVSVRLSSGTTAPKKTSFGSLKDEDRIFTN
                     LYGRHDWRLKGAQRRGDWYKTKEILLKGPDWILGEMKTSGLRGRGGAGFPTGLKWSFM
                     NKPSDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLVEGCLVGGRAMGARAAYIYIRG
                     EFYNEASNLQVAIREAYEAGLIGKNACDSDYDFDVFVVRGAGAYICGEETALIESIEG
                     KQGKPRLKPPFPADVGVFGCPTTVANVETVAVSPTICRRGGTWFAGFGRERNSGTKLF
                     NISGHVNHPCTVEEEMSVPLKELIEKHAGGVLGGWDNLLAVIPGGSSTPLIPKSVCET
                     VLMDFDALVQAQTGLGTAAVIVMNSSTDIVKAIARLIEFYKHESCGQCTPCREGVDWM
                     NKVMARFVKGDARPAEIDSLWEISKQIEGHTICALGDGAAWPVQGLIRHFRPELEDRM
                     QRFAQQHQARQAAS"
     exon            85..167
                     /gene="Ndufv1"
                     /inference="alignment:Splign:2.1.0"
     exon            168..338
                     /gene="Ndufv1"
                     /inference="alignment:Splign:2.1.0"
     exon            339..522
                     /gene="Ndufv1"
                     /inference="alignment:Splign:2.1.0"
     exon            523..712
                     /gene="Ndufv1"
                     /inference="alignment:Splign:2.1.0"
     exon            713..925
                     /gene="Ndufv1"
                     /inference="alignment:Splign:2.1.0"
     exon            926..1092
                     /gene="Ndufv1"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1174
                     /gene="Ndufv1"
                     /inference="alignment:Splign:2.1.0"
     exon            1175..1320
                     /gene="Ndufv1"
                     /inference="alignment:Splign:2.1.0"
     exon            1321..1481
                     /gene="Ndufv1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggcttccg cgatgctagc agcacggcat tttctcggcg ggtcggttcc cgtgcgggta
       61 tctgtgcgtc tcagcagcgg cacgacagca cccaagaaaa cctcatttgg ctcgctgaag
      121 gatgaagacc ggatcttcac caacctgtat gggcgccatg actggaggct gaagggtgcc
      181 cagaggcggg gtgattggta caagacaaag gagatcctgc tgaaggggcc tgactggatc
      241 ttgggtgaaa tgaagacatc gggtttacgg ggccgtggtg gtgctggctt ccccactggc
      301 ctcaaatgga gctttatgaa taagccctcg gatggcaggc ccaagtacct ggtggtgaat
      361 gctgacgagg gtgagcccgg cacctgtaag gaccgagaga tcatgcgcca tgaccctcac
      421 aagctggtgg aaggctgcct ggtgggaggc cgggccatgg gggcccgggc tgcctatatc
      481 tacatccgag gggaattcta caatgaggcc tccaatttgc aggtagctat ccgagaggcc
      541 tatgaagcag gtctgattgg caaaaatgcc tgtgactctg attatgattt tgatgtgttt
      601 gtggtgcgtg gggctggggc ctacatctgt ggagaagaga ctgcgcttat tgagtccatt
      661 gaaggcaagc agggaaagcc acgcctgaag ccgccctttc cagcagatgt gggagtattt
      721 ggatgcccca caactgtggc caatgtggag acggtggctg tgtcccccac catctgccgt
      781 cgtggcggca cctggtttgc tggctttggc cgagaacgca actcaggtac caaactgttc
      841 aacatctctg gccatgtcaa ccacccctgc actgtggagg aagagatgtc tgtgccactc
      901 aaagaactga ttgagaaaca tgctggtggt gtcttaggtg gctgggacaa cctccttgct
      961 gtgattcctg gtggctcatc cactccactg atccccaaat ctgtgtgtga gacagtgctg
     1021 atggactttg atgccctggt gcaggctcag acgggcctgg gcacagctgc ggttattgtt
     1081 atgaacagct cgacagacat tgtgaaagcc atcgctcgtc tcattgagtt ctacaagcat
     1141 gagagctgtg gccagtgcac cccgtgccgg gagggcgttg attggatgaa caaggtgatg
     1201 gcccgatttg tgaaggggga tgcccggcca gctgagatcg actccctgtg ggagatcagc
     1261 aagcagatag aaggccacac catttgtgct ctgggtgatg gggccgcctg gccagtacag
     1321 ggtctgatcc gacatttccg gcccgagctt gaggatcgga tgcaacgatt tgcccagcag
     1381 caccaggcca ggcaggcggc ctcctgagcc tgcatcctag cctgccaatt ttacatccct
     1441 ttgggaagct ggacaataaa caagtgctgc ccactctcca aaaaaaaaaa aaaaaaaaaa
     1501 aaaaaa
//
