LOCUS       NM_001008525             750 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus NADH:ubiquinone oxidoreductase core subunit S7
            (Ndufs7), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001008525 XM_343165
VERSION     NM_001008525.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 750)
  AUTHORS   Liu,Y., Qu,H.Q., Chang,X., Qu,J., Mentch,F.D., Nguyen,K., Tian,L.,
            Glessner,J., Sleiman,P.M.A. and Hakonarson,H.
  TITLE     Mutation burden analysis of six common mental disorders in African
            Americans by whole genome sequencing
  JOURNAL   Hum Mol Genet 31 (22), 3769-3776 (2022)
   PUBMED   35642741
REFERENCE   2  (bases 1 to 750)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   3  (bases 1 to 750)
  AUTHORS   Guo,R., Zong,S., Wu,M., Gu,J. and Yang,M.
  TITLE     Architecture of Human Mitochondrial Respiratory Megacomplex
            I2III2IV2
  JOURNAL   Cell 170 (6), 1247-1257 (2017)
   PUBMED   28844695
REFERENCE   4  (bases 1 to 750)
  AUTHORS   Frykman,S., Teranishi,Y., Hur,J.Y., Sandebring,A., Yamamoto,N.G.,
            Ancarcrona,M., Nishimura,T., Winblad,B., Bogdanovic,N.,
            Schedin-Weiss,S., Kihara,T. and Tjernberg,L.O.
  TITLE     Identification of two novel synaptic gamma-secretase associated
            proteins that affect amyloid beta-peptide levels without altering
            Notch processing
  JOURNAL   Neurochem Int 61 (1), 108-118 (2012)
   PUBMED   22521230
REFERENCE   5  (bases 1 to 750)
  AUTHORS   Leong,D.W., Komen,J.C., Hewitt,C.A., Arnaud,E., McKenzie,M.,
            Phipson,B., Bahlo,M., Laskowski,A., Kinkel,S.A., Davey,G.M.,
            Heath,W.R., Voss,A.K., Zahedi,R.P., Pitt,J.J., Chrast,R.,
            Sickmann,A., Ryan,M.T., Smyth,G.K., Thorburn,D.R. and Scott,H.S.
  TITLE     Proteomic and metabolomic analyses of mitochondrial complex
            I-deficient mouse model generated by spontaneous B2 short
            interspersed nuclear element (SINE) insertion into NADH
            dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) gene
  JOURNAL   J Biol Chem 287 (24), 20652-20663 (2012)
   PUBMED   22535952
REFERENCE   6  (bases 1 to 750)
  AUTHORS   Ugalde,C., Janssen,R.J., van den Heuvel,L.P., Smeitink,J.A. and
            Nijtmans,L.G.
  TITLE     Differences in assembly or stability of complex I and other
            mitochondrial OXPHOS complexes in inherited complex I deficiency
  JOURNAL   Hum Mol Genet 13 (6), 659-667 (2004)
   PUBMED   14749350
REFERENCE   7  (bases 1 to 750)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   8  (bases 1 to 750)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   9  (bases 1 to 750)
  AUTHORS   Murray,J., Zhang,B., Taylor,S.W., Oglesbee,D., Fahy,E.,
            Marusich,M.F., Ghosh,S.S. and Capaldi,R.A.
  TITLE     The subunit composition of the human NADH dehydrogenase obtained by
            rapid one-step immunopurification
  JOURNAL   J Biol Chem 278 (16), 13619-13622 (2003)
   PUBMED   12611891
REFERENCE   10 (bases 1 to 750)
  AUTHORS   Triepels,R.H., Hanson,B.J., van den Heuvel,L.P., Sundell,L.,
            Marusich,M.F., Smeitink,J.A. and Capaldi,R.A.
  TITLE     Human complex I defects can be resolved by monoclonal antibody
            analysis into distinct subunit assembly patterns
  JOURNAL   J Biol Chem 276 (12), 8892-8897 (2001)
   PUBMED   11112787
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086574.1.
            
            On Dec 16, 2004 this sequence version replaced XM_343165.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086574.1, FQ121859.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760476, SAMN06621351
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..750
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..750
                     /gene="Ndufs7"
                     /note="NADH:ubiquinone oxidoreductase core subunit S7"
                     /db_xref="GeneID:362837"
                     /db_xref="RGD:1310013"
     exon            1..23
                     /gene="Ndufs7"
                     /inference="alignment:Splign:2.1.0"
     CDS             8..664
                     /gene="Ndufs7"
                     /EC_number="7.1.1.2"
                     /note="NADH-ubiquinone oxidoreductase Fe-S protein 7; NADH
                     dehydrogenase (ubiquinone) Fe-S protein 7"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] iron-sulfur
                     protein 7, mitochondrial"
                     /protein_id="NP_001008525.1"
                     /db_xref="GeneID:362837"
                     /db_xref="RGD:1310013"
                     /translation="MAALAAPGLLSVRILGLRTGTVAQLRRAHQSVAATGSPSSTQSA
                     VSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMA
                     APRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCAN
                     GGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR
                     "
     exon            24..60
                     /gene="Ndufs7"
                     /inference="alignment:Splign:2.1.0"
     exon            61..126
                     /gene="Ndufs7"
                     /inference="alignment:Splign:2.1.0"
     exon            127..250
                     /gene="Ndufs7"
                     /inference="alignment:Splign:2.1.0"
     exon            251..430
                     /gene="Ndufs7"
                     /inference="alignment:Splign:2.1.0"
     exon            431..477
                     /gene="Ndufs7"
                     /inference="alignment:Splign:2.1.0"
     exon            478..566
                     /gene="Ndufs7"
                     /inference="alignment:Splign:2.1.0"
     exon            567..723
                     /gene="Ndufs7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggccaagatg gcggcgctgg cggctcctgg cttgctctct gtacggatcc tgggtctgcg
       61 cacaggcaca gtggctcagc tgcgcagagc ccaccagagt gtggcagcca ctgggagccc
      121 gagcagcaca cagtctgccg tgtccaaggc tggagctgga gccgtggtcc ctaagccctc
      181 ccatcttccc agaagccggg ccgagtatgt agtgaccaag ctggatgacc tcatcaactg
      241 ggcgcgccgg agctccctgt ggcctatgac cttcggcttg gcgtgctgtg ccgtggagat
      301 gatgcacatg gccgccccgc gctatgacat ggaccgcttt ggtgtggtgt tccgtgccag
      361 cccgcgccag gctgacgtga tgatcgtagc tggcacgctc actaacaaga tggctccagc
      421 actccgcaag gtgtacgacc agatgcccga accccggtat gtggtgtcca tggggagctg
      481 tgccaatggc ggtggctact accactactc ctactcggtt gttcgtggct gtgaccgaat
      541 tgtgccagtg gacatctatg tgccaggctg cccgcccacg gccgaggcgc tgctctacgg
      601 catcttgcag ctgcagcgga agatcaaacg cgaacagaag ctgaagatct ggtaccgcag
      661 gtagagctgc caagccgaac gtgaggatcc cagaatccct gtgaataaac ccgccctgat
      721 ccaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
