LOCUS       NM_001106426            1062 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus NADH:ubiquinone oxidoreductase subunit B5
            (Ndufb5), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001106426 XM_001066565 XM_215544
VERSION     NM_001106426.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Kang,K.W., Ko,J.Y., Lee,H., Shin,S.Y., Lee,W.S., Hong,J., Kim,S.W.,
            Lee,S.K. and Oak,M.H.
  TITLE     Surgically Metabolic Resection of Pericardial Fat to Ameliorate
            Myocardial Mitochondrial Dysfunction in Acute Myocardial Infarction
            Obese Rats
  JOURNAL   J Korean Med Sci 37 (9), e55 (2022)
   PUBMED   35257523
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  AUTHORS   Guo,R., Zong,S., Wu,M., Gu,J. and Yang,M.
  TITLE     Architecture of Human Mitochondrial Respiratory Megacomplex
            I2III2IV2
  JOURNAL   Cell 170 (6), 1247-1257 (2017)
   PUBMED   28844695
REFERENCE   3  (bases 1 to 1062)
  AUTHORS   Stroud,D.A., Surgenor,E.E., Formosa,L.E., Reljic,B., Frazier,A.E.,
            Dibley,M.G., Osellame,L.D., Stait,T., Beilharz,T.H., Thorburn,D.R.,
            Salim,A. and Ryan,M.T.
  TITLE     Accessory subunits are integral for assembly and function of human
            mitochondrial complex I
  JOURNAL   Nature 538 (7623), 123-126 (2016)
   PUBMED   27626371
REFERENCE   4  (bases 1 to 1062)
  AUTHORS   Kang,K.W., Kim,O.S., Chin,J.Y., Kim,W.H., Park,S.H., Choi,Y.J.,
            Shin,J.H., Jung,K.T., Lim,D.S. and Lee,S.K.
  TITLE     Diastolic Dysfunction Induced by a High-Fat Diet Is Associated with
            Mitochondrial Abnormality and Adenosine Triphosphate Levels in Rats
  JOURNAL   Endocrinol Metab (Seoul) 30 (4), 557-568 (2015)
   PUBMED   26790384
REFERENCE   5  (bases 1 to 1062)
  AUTHORS   Jarr,K.U., Eschricht,S., Burkly,L.C., Preusch,M., Katus,H.A.,
            Frey,N. and Chorianopoulos,E.
  TITLE     TNF-like weak inducer of apoptosis aggravates left ventricular
            dysfunction after myocardial infarction in mice
  JOURNAL   Mediators Inflamm 2014, 131950 (2014)
   PUBMED   24692845
REFERENCE   6  (bases 1 to 1062)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   7  (bases 1 to 1062)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   8  (bases 1 to 1062)
  AUTHORS   Murray,J., Zhang,B., Taylor,S.W., Oglesbee,D., Fahy,E.,
            Marusich,M.F., Ghosh,S.S. and Capaldi,R.A.
  TITLE     The subunit composition of the human NADH dehydrogenase obtained by
            rapid one-step immunopurification
  JOURNAL   J Biol Chem 278 (16), 13619-13622 (2003)
   PUBMED   12611891
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473961.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001066565.1, XM_215544.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB578773.1, FM093970.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q24"
     gene            1..1062
                     /gene="Ndufb5"
                     /note="NADH:ubiquinone oxidoreductase subunit B5"
                     /db_xref="GeneID:294964"
                     /db_xref="RGD:1305909"
     exon            1..198
                     /gene="Ndufb5"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..644
                     /gene="Ndufb5"
                     /note="NADH dehydrogenase (ubiquinone) 1 beta subcomplex,
                     5"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] 1 beta
                     subcomplex subunit 5, mitochondrial"
                     /protein_id="NP_001099896.1"
                     /db_xref="GeneID:294964"
                     /db_xref="RGD:1305909"
                     /translation="MAAMSLLQRASVAALTALSGRRAGTRLGVGSFLTRSFPKTVAPV
                     RHSGDHGKRLFVIKPSLYYDARFLRLMKFYLLLTGIPVIIGITLVNIFIGEAELAEIP
                     EGYIPEHWEYYKHPISRWIARTFYDGPEKNYEKTLAILQIESEKADLRLKELEVRRLM
                     RARGDGPWYQYPTPEKEFIDYSPKSTPDN"
     exon            199..287
                     /gene="Ndufb5"
                     /inference="alignment:Splign:2.1.0"
     exon            288..354
                     /gene="Ndufb5"
                     /inference="alignment:Splign:2.1.0"
     exon            355..416
                     /gene="Ndufb5"
                     /inference="alignment:Splign:2.1.0"
     exon            417..523
                     /gene="Ndufb5"
                     /inference="alignment:Splign:2.1.0"
     exon            524..1062
                     /gene="Ndufb5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attcgccttc actggtggat tgtccctccc ggctcccgtt gcctacccta cttccttccg
       61 tggctgtagt agccatggcg gctatgagcc tgctgcagcg ggcttcggtc gccgctctga
      121 cagctctgtc tggccgccgc gctggcacta ggctcggagt cggaagtttt ctcacacgga
      181 gctttccgaa gactgtcgct cctgtgcggc acagtgggga ccatggcaag agactgtttg
      241 tcatcaagcc ttccttatac tatgacgccc gcttcctgag attaatgaaa ttctaccttt
      301 tgttgactgg gatcccagtt ataatcggca taacactggt gaacatattt attggtgaag
      361 ctgaactcgc agaaatccca gaaggctaca tcccagaaca ctgggagtat tacaagcatc
      421 caatatcacg atggattgcc cggactttct acgatggacc tgaaaagaac tatgaaaaga
      481 ccctggctat cctccagatc gagtctgaaa aggccgactt acggttaaag gagctggagg
      541 ttcgaagact gatgcgtgcc cggggtgatg gaccttggta tcaatatcca acccctgaaa
      601 aggagttcat tgattattct ccaaaatcaa ctcctgacaa ctgatgattc gtctgttcct
      661 ctagtgggaa gaaaggaata aatactctgt attttcactc ggatgcacac aagcttctgt
      721 ggctgtttct tcatgtggtt caggtgatgc gtttgttctc ttggtccttt cagcttcatc
      781 tgttgcggtt tacagggcaa taataaaagc tagaggcctg ggaacttgtg atttcctaaa
      841 gtgacactgt tgataacctt cgtctggcag ggagacggtg cagaggtcct gtgagtgagt
      901 attcaggaac tgtgatcttt gccattgcag gtggggttac ttgggactac ttggaatttt
      961 aacttcacaa gaaatactga actaaccata taaaattatc agcactagaa taaataaact
     1021 agtagactag tctttagtaa acgagtctta gagtttatcc tg
//
