LOCUS       NM_001037338             534 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus NADH:ubiquinone oxidoreductase subunit B4
            (Ndufb4), mRNA.
ACCESSION   NM_001037338 XM_213619
VERSION     NM_001037338.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Guo,R., Zong,S., Wu,M., Gu,J. and Yang,M.
  TITLE     Architecture of Human Mitochondrial Respiratory Megacomplex
            I2III2IV2
  JOURNAL   Cell 170 (6), 1247-1257 (2017)
   PUBMED   28844695
REFERENCE   2  (bases 1 to 534)
  AUTHORS   Stroud,D.A., Surgenor,E.E., Formosa,L.E., Reljic,B., Frazier,A.E.,
            Dibley,M.G., Osellame,L.D., Stait,T., Beilharz,T.H., Thorburn,D.R.,
            Salim,A. and Ryan,M.T.
  TITLE     Accessory subunits are integral for assembly and function of human
            mitochondrial complex I
  JOURNAL   Nature 538 (7623), 123-126 (2016)
   PUBMED   27626371
REFERENCE   3  (bases 1 to 534)
  AUTHORS   Zhao,X., Leon,I.R., Bak,S., Mogensen,M., Wrzesinski,K., Hojlund,K.
            and Jensen,O.N.
  TITLE     Phosphoproteome analysis of functional mitochondria isolated from
            resting human muscle reveals extensive phosphorylation of inner
            membrane protein complexes and enzymes
  JOURNAL   Mol Cell Proteomics 10 (1), M110.000299 (2011)
   PUBMED   20833797
REFERENCE   4  (bases 1 to 534)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   5  (bases 1 to 534)
  AUTHORS   Murray,J., Taylor,S.W., Zhang,B., Ghosh,S.S. and Capaldi,R.A.
  TITLE     Oxidative damage to mitochondrial complex I due to peroxynitrite:
            identification of reactive tyrosines by mass spectrometry
  JOURNAL   J Biol Chem 278 (39), 37223-37230 (2003)
   PUBMED   12857734
REFERENCE   6  (bases 1 to 534)
  AUTHORS   Murray,J., Zhang,B., Taylor,S.W., Oglesbee,D., Fahy,E.,
            Marusich,M.F., Ghosh,S.S. and Capaldi,R.A.
  TITLE     The subunit composition of the human NADH dehydrogenase obtained by
            rapid one-step immunopurification
  JOURNAL   J Biol Chem 278 (16), 13619-13622 (2003)
   PUBMED   12611891
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Apr 8, 2021 this sequence version replaced NM_001037338.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ217067.1, CB732095.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-270               JAXUCZ010000011.1  76569178-76569447
            271-417             JAXUCZ010000011.1  76574140-76574286
            418-534             JAXUCZ010000011.1  76575763-76575879
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     gene            1..534
                     /gene="Ndufb4"
                     /note="NADH:ubiquinone oxidoreductase subunit B4"
                     /db_xref="GeneID:288088"
                     /db_xref="RGD:1307072"
     exon            1..270
                     /gene="Ndufb4"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..480
                     /gene="Ndufb4"
                     /note="NADH dehydrogenase (ubiquinone) 1 beta subcomplex,
                     4, 15kDa; NADH dehydrogenase (ubiquinone) 1 beta
                     subcomplex 4"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] 1 beta
                     subcomplex subunit 4"
                     /protein_id="NP_001032415.1"
                     /db_xref="GeneID:288088"
                     /db_xref="RGD:1307072"
                     /translation="MSFSKYKPAPLAALPNTLDPAEYDVSPETRKAQVERMSIRARLK
                     REYLLQYNDPKRQTHIEDPALIRWTYARSANVYPNFRPTPKNSLLGAVAGLGPLIFWY
                     YVIKTDRDKKERLIQEGKLDRKFSISY"
     exon            271..417
                     /gene="Ndufb4"
                     /inference="alignment:Splign:2.1.0"
     exon            418..534
                     /gene="Ndufb4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcgcaggc gcacttcctg agtctgaagg tcaaactaaa gagggcagcc cttatatccg
       61 cgcaggcgca aatgttcgcc gggagccaag atgtcgtttt ccaagtataa gcctgcaccc
      121 ctggccgctc tccccaatac cctcgacccc gccgagtatg acgtgtctcc ggagacccga
      181 aaggcgcagg tcgagcgcat gagcataagg gcccggctta aacgggagta tctgcttcag
      241 tacaacgacc ccaaacgcca aacgcacatc gaggatcctg ccttgattcg ttggacctat
      301 gcaagatcag caaatgttta tcctaatttc agacccactc ccaagaactc acttttagga
      361 gcagtggcag gtttagggcc tctcatcttc tggtattacg ttatcaaaac agacagggac
      421 aaaaaggaaa gacttatcca ggaaggaaaa ctggacagaa aatttagcat ctcctactaa
      481 gttcggcaag gatgcctctg ttcttgcatc aataaatctc ctattaatca gtca
//
