LOCUS       NM_001108624             484 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Rattus norvegicus NADH:ubiquinone oxidoreductase subunit B2
            (Ndufb2), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001108624 XM_001070173 XM_342664
VERSION     NM_001108624.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Guo,R., Zong,S., Wu,M., Gu,J. and Yang,M.
  TITLE     Architecture of Human Mitochondrial Respiratory Megacomplex
            I2III2IV2
  JOURNAL   Cell 170 (6), 1247-1257 (2017)
   PUBMED   28844695
REFERENCE   3  (bases 1 to 484)
  AUTHORS   Stroud,D.A., Surgenor,E.E., Formosa,L.E., Reljic,B., Frazier,A.E.,
            Dibley,M.G., Osellame,L.D., Stait,T., Beilharz,T.H., Thorburn,D.R.,
            Salim,A. and Ryan,M.T.
  TITLE     Accessory subunits are integral for assembly and function of human
            mitochondrial complex I
  JOURNAL   Nature 538 (7623), 123-126 (2016)
   PUBMED   27626371
REFERENCE   4  (bases 1 to 484)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 484)
  AUTHORS   Murray,J., Zhang,B., Taylor,S.W., Oglesbee,D., Fahy,E.,
            Marusich,M.F., Ghosh,S.S. and Capaldi,R.A.
  TITLE     The subunit composition of the human NADH dehydrogenase obtained by
            rapid one-step immunopurification
  JOURNAL   J Biol Chem 278 (16), 13619-13622 (2003)
   PUBMED   12611891
REFERENCE   6  (bases 1 to 484)
  AUTHORS   Xiao,H.S., Huang,Q.H., Zhang,F.X., Bao,L., Lu,Y.J., Guo,C.,
            Yang,L., Huang,W.J., Fu,G., Xu,S.H., Cheng,X.P., Yan,Q., Zhu,Z.D.,
            Zhang,X., Chen,Z., Han,Z.G. and Zhang,X.
  TITLE     Identification of gene expression profile of dorsal root ganglion
            in the rat peripheral axotomy model of neuropathic pain
  JOURNAL   Proc Natl Acad Sci U S A 99 (12), 8360-8365 (2002)
   PUBMED   12060780
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            C06706.1, BC166901.1 and BG668360.1.
            
            On Jan 1, 2009 this sequence version replaced NM_001108624.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CO554907.1, CA339767.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                C06706.1           1-23
            24-450              BC166901.1         1-427
            451-484             BG668360.1         311-344
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q23"
     gene            1..484
                     /gene="Ndufb2"
                     /note="NADH:ubiquinone oxidoreductase subunit B2"
                     /db_xref="GeneID:362344"
                     /db_xref="RGD:1308130"
     exon            1..133
                     /gene="Ndufb2"
                     /inference="alignment:Splign:2.1.0"
     CDS             36..353
                     /gene="Ndufb2"
                     /note="NADH dehydrogenase (ubiquinone) 1 beta subcomplex,
                     2"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] 1 beta
                     subcomplex subunit 2, mitochondrial"
                     /protein_id="NP_001102094.2"
                     /db_xref="GeneID:362344"
                     /db_xref="RGD:1308130"
                     /translation="MSALARLAPFGRVGGRLLRGCRARAAGDGGVRHVGDGGHIQPRY
                     REFPQLTQSQVIHGEVLSSLMWFWILWRFWHDSDAVLGHFSYPDPSKWTDEELGVPPD
                     DED"
     exon            134..278
                     /gene="Ndufb2"
                     /inference="alignment:Splign:2.1.0"
     exon            279..377
                     /gene="Ndufb2"
                     /inference="alignment:Splign:2.1.0"
     exon            378..457
                     /gene="Ndufb2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacgcatcag gggtggggac tgctctcccg ctaggatgtc tgcgctggcc cgcctggcac
       61 ctttcggtcg cgttggaggc cgcctgcttc ggggctgccg cgcgcgggca gctggagacg
      121 gtggagtccg tcatgttggc gatggtggac acattcagcc ccggtacagg gagtttcccc
      181 agcttaccca gtcccaggtg atccatggtg aggtcttaag ctcactcatg tggttctgga
      241 ttctttggag attttggcat gactcggatg ctgtgctggg tcacttttca tatccagatc
      301 catcgaagtg gacagatgaa gaactggggg tccctcctga cgacgaggac tgaaagtgta
      361 aactcctctc tgtacgagag caaggtgaga caattcaaga aattacagcc ctcattaaag
      421 gtgtaaatta aagtagcttg ccaaaatgag gaaccgaaaa aaaaaaaaaa aaaaaaaaaa
      481 aaaa
//
