LOCUS       NM_001008318            2406 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus NADH:ubiquinone oxidoreductase complex assembly
            factor 7 (Ndufaf7), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001008318 XM_216627
VERSION     NM_001008318.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2406)
  AUTHORS   Zurita Rendon,O., Silva Neiva,L., Sasarman,F. and Shoubridge,E.A.
  TITLE     The arginine methyltransferase NDUFAF7 is essential for complex I
            assembly and early vertebrate embryogenesis
  JOURNAL   Hum Mol Genet 23 (19), 5159-5170 (2014)
   PUBMED   24838397
REFERENCE   2  (bases 1 to 2406)
  AUTHORS   Rhein,V.F., Carroll,J., Ding,S., Fearnley,I.M. and Walker,J.E.
  TITLE     NDUFAF7 methylates arginine 85 in the NDUFS2 subunit of human
            complex I
  JOURNAL   J Biol Chem 288 (46), 33016-33026 (2013)
   PUBMED   24089531
REFERENCE   3  (bases 1 to 2406)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   4  (bases 1 to 2406)
  AUTHORS   Carilla-Latorre,S., Gallardo,M.E., Annesley,S.J., Calvo-Garrido,J.,
            Grana,O., Accari,S.L., Smith,P.K., Valencia,A., Garesse,R.,
            Fisher,P.R. and Escalante,R.
  TITLE     MidA is a putative methyltransferase that is required for
            mitochondrial complex I function
  JOURNAL   J Cell Sci 123 (Pt 10), 1674-1683 (2010)
   PUBMED   20406883
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083810.1.
            
            On Dec 16, 2004 this sequence version replaced XM_216627.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083810.1, SRR8487226.103227.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2406
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q12"
     gene            1..2406
                     /gene="Ndufaf7"
                     /gene_synonym="RGD1311578"
                     /note="NADH:ubiquinone oxidoreductase complex assembly
                     factor 7"
                     /db_xref="GeneID:298748"
                     /db_xref="RGD:1311578"
     exon            1..55
                     /gene="Ndufaf7"
                     /gene_synonym="RGD1311578"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..1329
                     /gene="Ndufaf7"
                     /gene_synonym="RGD1311578"
                     /EC_number="2.1.1.320"
                     /note="protein midA homolog, mitochondrial; NADH
                     dehydrogenase [ubiquinone] complex I, assembly factor 7;
                     NADH dehydrogenase (ubiquinone) complex I, assembly factor
                     7; protein arginine methyltransferase NDUFAF7,
                     mitochondrial"
                     /codon_start=1
                     /product="protein arginine methyltransferase NDUFAF7,
                     mitochondrial precursor"
                     /protein_id="NP_001008319.1"
                     /db_xref="GeneID:298748"
                     /db_xref="RGD:1311578"
                     /translation="MNALVRRCVARTGIPSIWRRKCFSSGNEPAESNHVTPMLRHLMY
                     KIKSTGPITVAEYMKEVLTNPAKGYYVHHDMLGEKGDFITSPEISQIFGELLGVWFVS
                     EWMASGKSTAFQLVELGPGRGTLTADILRVFSQLGSVLKTCDISIHLVEVSQKLSEIQ
                     ALTLTEETVPLERDAESLVYMKGVTKSGIPISWYRDLKDVPTGYSFYLAHEFFDVLPV
                     HKFQKTPHGWREVFVDIDPQSPDKLRFVLAPCATPAEAFIQRDERREHVEVCPDAGVV
                     IQELSQRIASTGGAALIADYGHDGTKTDTLRGFYEHQLHDVLTAPGTADLTADVDFSY
                     LRRMAQGRVASLGPVEQRTFLKNMGIDVRLKVLLDKAGDPSLQQQLLRGYDMLMNPQK
                     MGERFHFFALLPHQRLHVGSQGGKACQSEAPSTSVPGFDELVWH"
     exon            56..219
                     /gene="Ndufaf7"
                     /gene_synonym="RGD1311578"
                     /inference="alignment:Splign:2.1.0"
     exon            220..300
                     /gene="Ndufaf7"
                     /gene_synonym="RGD1311578"
                     /inference="alignment:Splign:2.1.0"
     exon            301..411
                     /gene="Ndufaf7"
                     /gene_synonym="RGD1311578"
                     /inference="alignment:Splign:2.1.0"
     exon            412..625
                     /gene="Ndufaf7"
                     /gene_synonym="RGD1311578"
                     /inference="alignment:Splign:2.1.0"
     exon            626..684
                     /gene="Ndufaf7"
                     /gene_synonym="RGD1311578"
                     /inference="alignment:Splign:2.1.0"
     exon            685..795
                     /gene="Ndufaf7"
                     /gene_synonym="RGD1311578"
                     /inference="alignment:Splign:2.1.0"
     exon            796..939
                     /gene="Ndufaf7"
                     /gene_synonym="RGD1311578"
                     /inference="alignment:Splign:2.1.0"
     exon            940..1113
                     /gene="Ndufaf7"
                     /gene_synonym="RGD1311578"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..2373
                     /gene="Ndufaf7"
                     /gene_synonym="RGD1311578"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggccccgagg tggttggaat gaatgctttg gtgagacgct gtgtggcccg cacgggcatt
       61 cccagtattt ggagaaggaa gtgcttcagc tccgggaatg agccggcaga aagcaaccac
      121 gtgacaccga tgctgcggca tcttatgtat aaaataaagt ctacaggtcc catcactgtg
      181 gccgagtaca tgaaggaggt tttgaccaat ccagccaagg gatattacgt gcaccatgat
      241 atgctaggag aaaagggaga ctttattact tcacctgaaa taagtcaaat cttcggggag
      301 ctactcgggg tgtggttcgt tagtgaatgg atggcctccg gaaagagtac agccttccag
      361 ctggtggaac ttggtccagg tcggggtacc ctcacagcag atattttgag ggtgttcagt
      421 cagcttgggt ctgtgctaaa aacctgtgac atttcaatac accttgtaga ggtgagccaa
      481 aagttaagtg agatccaagc actgacactg accgaggaga cagtcccttt ggagagagat
      541 gctgaatccc tagtgtacat gaaaggtgtc acgaagtctg ggattccaat ctcctggtat
      601 cgagacctga aggatgttcc tacaggatac agcttttatc tcgcacatga gttttttgat
      661 gttcttcctg tgcataaatt tcagaaaaca ccacatggat ggagagaagt gtttgttgat
      721 atcgacccac aatctcctga taaactgagg ttcgtcttgg cgccttgtgc gactccagca
      781 gaagccttca tacaacgcga tgaaagaagg gagcatgtgg aggtttgtcc tgatgctggg
      841 gttgtcatcc aggaactgtc ccagcgcatt gcatcaactg gaggtgctgc cctgattgcg
      901 gattacggtc acgatggaac aaagactgac accttgagag ggttttatga acaccagctg
      961 cacgatgtcc tgacagctcc tggaacagca gacctgacag ctgacgtaga cttcagttac
     1021 ctgcgcagaa tggcacaagg acgagtagct tctctgggtc ccgtggaaca aagaacattt
     1081 ctaaaaaaca tgggcattga tgtgcggctg aaggttcttt tggataaagc aggtgaccca
     1141 tccctgcagc agcagctact tcggggatac gatatgctaa tgaatcctca gaagatggga
     1201 gagagatttc acttctttgc cttgctgcct catcagagac ttcatgtggg aagtcaagga
     1261 gggaaggcct gccagtcaga agccccctcg acctctgtac ctgggtttga tgaactggtt
     1321 tggcactgat atttcagctg ccttgattat cagaataaaa gaaattcact ttgcatactg
     1381 aagttgactt aagtactcac actgtcaact cttttcagtc gatggcctgt tttatatgaa
     1441 cacaatcaaa acggtaaaat gttaaaggtt ataaccaact cctggtataa ttgttttcaa
     1501 cccagtgaag cagtttattg tgaaattgtt tcctttatca aattactgta tttctactta
     1561 ctttttaaaa acatatgagc actgattggt ttgctatttt cagggatccg agtcaacaga
     1621 tctggatatt tttaaagggc aaaaggcagt gtattctgat agaaggctct ctaaggttta
     1681 gtatttgaaa gaagtcagat gtgagtttct agagttaaga tcctgttttt gctgaggaga
     1741 taattaactg aatatgccag tatacacttg gttctctggt ctgtggagtg cacagatgaa
     1801 ggcagagtga ctggtaagga gtcagcagtt ctccattctg gaagcaggat tcagaataca
     1861 catgcttctg tggatgaaag taaagactga taactacaat tttaaagaag tcataagtca
     1921 tagttaaaaa gactgcagca aatctgactt ttactgaagt aagaattaag agcaatgtta
     1981 actatccagg aggaacaatt tcctaggctg agctcattct gttgtatttt caggtcaata
     2041 cacaatttta gttctgtatt aaattggtct gtagaaccat tctatttatc ctgtaaatgg
     2101 gcattcctta tcagcagcag tcctgaggag ctgaggtggg aatggtatta gccatgcctc
     2161 agcctgtggt aactgcagtg aaagtcactg atggagtggt atgccactga ctcatttatt
     2221 cccgtttccg cttagccgag cgtggcctta accttctgtg tcttcgtctg tgagagggac
     2281 caggctagaa cacttgaaag aagtaaataa ttacttatat tattctttgt gctggcatcc
     2341 caataaacga accctctaga taattatgtc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2401 aaaaaa
//
