LOCUS       NM_001108813             440 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus NADH:ubiquinone oxidoreductase subunit A1
            (Ndufa1), mRNA.
ACCESSION   NM_001108813 XM_001063150 XM_343760
VERSION     NM_001108813.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Stroud DA, Surgenor EE, Formosa LE, Reljic B, Frazier AE, Dibley
            MG, Osellame LD, Stait T, Beilharz TH, Thorburn DR, Salim A and
            Ryan MT.
  TITLE     Accessory subunits are integral for assembly and function of human
            mitochondrial complex I
  JOURNAL   Nature 538 (7623), 123-126 (2016)
   PUBMED   27626371
REFERENCE   2  (bases 1 to 440)
  AUTHORS   Vogel RO, Dieteren CE, van den Heuvel LP, Willems PH, Smeitink JA,
            Koopman WJ and Nijtmans LG.
  TITLE     Identification of mitochondrial complex I assembly intermediates by
            tracing tagged NDUFS3 demonstrates the entry point of mitochondrial
            subunits
  JOURNAL   J Biol Chem 282 (10), 7582-7590 (2007)
   PUBMED   17209039
REFERENCE   3  (bases 1 to 440)
  AUTHORS   Lamhonwah AM and Tein I.
  TITLE     Novel localization of OCTN1, an organic cation/carnitine
            transporter, to mammalian mitochondria
  JOURNAL   Biochem Biophys Res Commun 345 (4), 1315-1325 (2006)
   PUBMED   16729965
REFERENCE   4  (bases 1 to 440)
  AUTHORS   Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl
            E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES and
            Mann M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 440)
  AUTHORS   Murray J, Zhang B, Taylor SW, Oglesbee D, Fahy E, Marusich MF,
            Ghosh SS and Capaldi RA.
  TITLE     The subunit composition of the human NADH dehydrogenase obtained by
            rapid one-step immunopurification
  JOURNAL   J Biol Chem 278 (16), 13619-13622 (2003)
   PUBMED   12611891
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB567280.1, FM054992.1 and BC168213.1.
            
            On Mar 28, 2012 this sequence version replaced NM_001108813.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB802130.1, CB315398.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                CB567280.1         18-32
            16-416              FM054992.1         1-401
            417-440             BC168213.1         2549-2572
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq35"
     gene            1..440
                     /gene="Ndufa1"
                     /gene_synonym="RGD1560955"
                     /note="NADH:ubiquinone oxidoreductase subunit A1"
                     /db_xref="GeneID:363441"
                     /db_xref="RGD:1560955"
     exon            1..188
                     /gene="Ndufa1"
                     /gene_synonym="RGD1560955"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..299
                     /gene="Ndufa1"
                     /gene_synonym="RGD1560955"
                     /EC_number="1.6.99.3"
                     /note="NADH dehydrogenase (ubiquinone) 1 alpha subcomplex,
                     1"
                     /codon_start=1
                     /product="NADH dehydrogenase [ubiquinone] 1 alpha
                     subcomplex subunit 1"
                     /protein_id="NP_001102283.2"
                     /db_xref="GeneID:363441"
                     /db_xref="RGD:1560955"
                     /translation="MWFEILPGLAIMGVCLVIPGVSTAYIHKFTNGGKEKRVARVHYQ
                     WYLMERDRRISGVNRYYVSKGLENID"
     exon            189..278
                     /gene="Ndufa1"
                     /gene_synonym="RGD1560955"
                     /inference="alignment:Splign:2.1.0"
     exon            279..425
                     /gene="Ndufa1"
                     /gene_synonym="RGD1560955"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgctgccgg aagagcggtg aagcccccgg tcacctctga ggagccggta acggtgacgg
       61 gttggagtgt gagtaacggt gaggagatgt ggttcgagat tctccctggc ctcgccatta
      121 tgggggtgtg cctggtcatc cccggggtgt ccactgcgta catccacaag ttcaccaacg
      181 ggggcaagga aaagagagtt gctcgagttc attaccaatg gtatttgatg gaacgcgata
      241 gacgcatctc tggtgtcaat cgctactatg tgtccaaggg cctggagaac attgactaag
      301 gaagcatttt cctggctgat gaaaaaaatt actcagctat ggtcatctgt tcctgttaga
      361 aggctgtgca gcatattata tactatgcac atgttatgaa atgcataata aaaagtaaaa
      421 aaaaaaaaaa aaaaaaaaaa
//
