LOCUS       NP_001386464             568 aa            linear   ROD 01-APR-2024
DEFINITION  protein NDNF precursor [Rattus norvegicus].
ACCESSION   NP_001386464 XP_038964621
VERSION     NP_001386464.1
DBSOURCE    REFSEQ: accession NM_001399535.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 568)
  AUTHORS   Ohashi,K., Enomoto,T., Joki,Y., Shibata,R., Ogura,Y., Kataoka,Y.,
            Shimizu,Y., Kambara,T., Uemura,Y., Yuasa,D., Matsuo,K.,
            Hayakawa,S., Hiramatsu-Ito,M., Murohara,T. and Ouchi,N.
  TITLE     Neuron-derived neurotrophic factor functions as a novel modulator
            that enhances endothelial cell function and revascularization
            processes
  JOURNAL   J Biol Chem 289 (20), 14132-14144 (2014)
   PUBMED   24706764
REFERENCE   2  (residues 1 to 568)
  AUTHORS   Kuang,X.L., Zhao,X.M., Xu,H.F., Shi,Y.Y., Deng,J.B. and Sun,G.T.
  TITLE     Spatio-temporal expression of a novel neuron-derived neurotrophic
            factor (NDNF) in mouse brains during development
  JOURNAL   BMC Neurosci 11, 137 (2010)
   PUBMED   20969804
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 568)
  AUTHORS   Manabe,R., Tsutsui,K., Yamada,T., Kimura,M., Nakano,I., Shimono,C.,
            Sanzen,N., Furutani,Y., Fukuda,T., Oguri,Y., Shimamoto,K.,
            Kiyozumi,D., Sato,Y., Sado,Y., Senoo,H., Yamashina,S., Fukuda,S.,
            Kawai,J., Sugiura,N., Kimata,K., Hayashizaki,Y. and Sekiguchi,K.
  TITLE     Transcriptome-based systematic identification of extracellular
            matrix proteins
  JOURNAL   Proc Natl Acad Sci U S A 105 (35), 12849-12854 (2008)
   PUBMED   18757743
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Jan 10, 2022 this sequence version replaced XP_038964621.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.16651.1,
                                           SRR26643290.16298.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q31"
     Protein         1..568
                     /product="protein NDNF precursor"
                     /note="protein NDNF"
                     /calculated_mol_wt=62442
     sig_peptide     1..19
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2282
     Region          192..335
                     /region_name="NDNF"
                     /note="Neuron-derived neurotrophic factor, first Fn(III)
                     domain; pfam10179"
                     /db_xref="CDD:462981"
     Region          394..568
                     /region_name="NDNF_C"
                     /note="Neuron-derived Neurotrophic Factor C-terminal;
                     pfam19433"
                     /db_xref="CDD:466079"
     CDS             1..568
                     /gene="Ndnf"
                     /gene_synonym="AABR07060833.1; RGD1311080"
                     /coded_by="NM_001399535.1:489..2195"
                     /db_xref="GeneID:312401"
                     /db_xref="RGD:1311080"
ORIGIN      
        1 mellywcllc lllpltsrtq klptrdeelf qmqirdkalf hdssvipdga eissylfrdt
       61 prryffmvee dntplsvtvt pcdaplewkl slqelpeess adgsgdpepl dqqkqqmtdv
      121 egtelfsykg ndveyflsss spsglyqlel lstekdthfk vyatttpesd qpypdlpydp
      181 rvdvtsigrt tvtlawkqsp tasmlkqpie ycvvinkehn fkslcaaetk msaddafmva
      241 pkpgldfspf dfahfgfptd nlgkdrsfla kpspkvgrhv ywrpkvdikk icigsknift
      301 vsdlkpntqy yfdvfmvntn tnmstafvga fartkeeakq ktvelkdgrv tdvvvkrkgk
      361 kflrfapvss hqkvtlfihs cmdtvqvqvr rdgklllsqn vegirqfqlr gkpkgkylir
      421 lkgnkkgasm lkilattrps khafpslpdd trikafdklr tcssvtvawl gtqerrkfci
      481 yrkevggnys eeqkrrernq clgpdtrkks ekvlckyfhs qnlqkavtte tirdlqpgks
      541 ylldvyvvgh gghsvkyqsk lvktrkvc
//
