LOCUS       NM_001108390            2110 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus Nedd4 family interacting protein 2 (Ndfip2),
            mRNA.
ACCESSION   NM_001108390 XM_001077197 XM_341374
VERSION     NM_001108390.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2110)
  AUTHORS   Foot,N.J., Dalton,H.E., Shearwin-Whyatt,L.M., Dorstyn,L., Tan,S.S.,
            Yang,B. and Kumar,S.
  TITLE     Regulation of the divalent metal ion transporter DMT1 and iron
            homeostasis by a ubiquitin-dependent mechanism involving Ndfips and
            WWP2
  JOURNAL   Blood 112 (10), 4268-4275 (2008)
   PUBMED   18776082
REFERENCE   2  (bases 1 to 2110)
  AUTHORS   Cristillo,A.D., Nie,L., Macri,M.J. and Bierer,B.E.
  TITLE     Cloning and characterization of N4WBP5A, an inducible,
            cyclosporine-sensitive, Nedd4-binding protein in human T
            lymphocytes
  JOURNAL   J Biol Chem 278 (36), 34587-34597 (2003)
   PUBMED   12796489
REFERENCE   3  (bases 1 to 2110)
  AUTHORS   Matsuda,A., Suzuki,Y., Honda,G., Muramatsu,S., Matsuzaki,O.,
            Nagano,Y., Doi,T., Shimotohno,K., Harada,T., Nishida,E., Hayashi,H.
            and Sugano,S.
  TITLE     Large-scale identification and characterization of human genes that
            activate NF-kappaB and MAPK signaling pathways
  JOURNAL   Oncogene 22 (21), 3307-3318 (2003)
   PUBMED   12761501
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB697675.1, CO398212.1, DY565248.1, FM044778.1, DV728397.1 and
            BP495172.1.
            
            On Jul 9, 2010 this sequence version replaced NM_001108390.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EV767579.1, SRR8487231.125098.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-217               CB697675.1         1-217
            218-825             CO398212.1         1-608
            826-1141            DY565248.1         388-703
            1142-1595           FM044778.1         191-644
            1596-2108           DV728397.1         147-659
            2109-2110           BP495172.1         3-4                 c
FEATURES             Location/Qualifiers
     source          1..2110
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q22"
     gene            1..2110
                     /gene="Ndfip2"
                     /note="Nedd4 family interacting protein 2"
                     /db_xref="GeneID:361089"
                     /db_xref="RGD:1309716"
     exon            1..424
                     /gene="Ndfip2"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..1114
                     /gene="Ndfip2"
                     /codon_start=1
                     /product="NEDD4 family-interacting protein 2"
                     /protein_id="NP_001101860.2"
                     /db_xref="GeneID:361089"
                     /db_xref="RGD:1309716"
                     /translation="MGRRRSQRACASAPSMLSSARGSPELRRRSASEAEVSAAAEGAT
                     GSEVAPPGDRGGRTRGSGRGSAATASSTGEAEGAERGADTPARKPDPEAGRMDHHQLG
                     TGRYQVLHNEDDNSESSAPEQPSASSSAAQPVEAAASAPALDADSSPPPYSSITVDGP
                     TTSDADVYSEFYPVPPPYSVATSLPTYDEAEKAKAAALAAAAADAPQRNQEEECPPRD
                     DFSDVEQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKW
                     ILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYF
                     FLL"
     exon            425..590
                     /gene="Ndfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            591..724
                     /gene="Ndfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            725..818
                     /gene="Ndfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            819..943
                     /gene="Ndfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1010
                     /gene="Ndfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1116
                     /gene="Ndfip2"
                     /inference="alignment:Splign:2.1.0"
     exon            1117..2110
                     /gene="Ndfip2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcccactcc cgaccggctg acaacctaga gggctccccg ggacttgcct gacttttcca
       61 tctcctccca cctagggaca ccttcggagc ggggcctccg atgggacgcc ggcggagcca
      121 gagagcatgc gcgtccgccc cgagcatgct cagtagcgcg cgcggctccc cggagctccg
      181 acgccgatcg gcgagcgaag cggaggtctc cgccgcagcc gagggagcga caggaagtga
      241 agtggccccg ccgggcgacc gcggcggcag aacgcgaggc agcggaaggg gctctgcggc
      301 gacggcgtcg tcgaccgggg aggccgaggg agctgagcgc ggggcagaca cgcccgctcg
      361 gaagccggac cccgaggcgg gcaggatgga tcaccaccag ctggggactg gccgctacca
      421 ggtgcttcac aacgaggacg ataactcaga atcatctgcc ccagagcagc cgtcagcttc
      481 cagctcagca gcacagcctg tggaggctgc tgcctcagcg ccagccctgg acgccgactc
      541 ttctcctcca ccttacagca gcatcactgt ggacggtccc acaacttcag atgctgacgt
      601 gtacagtgag ttttaccctg tgccccctcc gtacagcgtc gctacctctc tcccgacata
      661 cgatgaggct gaaaaggcta aagctgctgc cctggccgct gcagcagcag acgcacctca
      721 aagaaaccaa gaggaagagt gtccacccag ggatgacttc agtgatgtgg agcagctcag
      781 agtaggcaat gatggcattt tcatgctggc ctttttcatg gcattcatat tcaactggct
      841 tggattctgc ttatccttct gtatcaccaa taccatagct ggaagatacg gtgctatctg
      901 tggatttggc ctctcactga tcaaatggat ccttattgtc aggttttcgg actattttac
      961 tggctatttc aatggacaat attggctttg gtggatattt cttgtacttg gcctgctcct
     1021 tttcttcaga ggatttgtta attacctaaa ggtcagaaac atgtctgaaa gtatggcagc
     1081 tgcgcacaga acaagatact tcttccttct ctagaggtgg cgtcaaccca acattcctct
     1141 cttacaccaa tgtgaaatgt ccaagtcgtc tgtaaaccta caacttcgct aagatagact
     1201 actgagcgca gaagcagatg tagtgagggg tggagcgtcg gaattaaatg acagggtggt
     1261 ttatgctaca agccatgtct gttcattcct taattctctt tggtatctca atttattttg
     1321 cacatttgca tatgtgcctg tttaaagggt atgcatatac ttgaaagaat ctgtaaagtt
     1381 gtagcagcaa agtccagtcc tacttggtta atcagtgttt gatacaattg gaagagttga
     1441 gtactaaaca gtcttccagc atgtaaatgc ttctgacttg accattagcg taataaaaat
     1501 tacattatta atcttgtcaa atgctttagt ttctggctct tagattcacc tagtaattcc
     1561 acacacgaaa tattctttgt tatatatgat gtttattaaa acttgcagta tgattattag
     1621 aaagaatttg tcagattttt aaatatgata ttatttagga aatctgtaaa taaccatgca
     1681 taagttgctc tttacattct tttcttaaat tgtgtctaga tatcttttca ttaattttaa
     1741 attaagtaaa ctaaatacat agaaataaac ttcattaaag atggagtggt ttagggtgaa
     1801 ctttaagaaa gtatgagtat accaaatgct gtttaaagaa caagttaggg ccacaccagt
     1861 tttaggggtt ttcagatgag aaccttacat tttaagatta ctcaccttac aattcttaca
     1921 agaagagatt gctttagacc ttatatttat tacatctaag acaatttaaa aaattaattt
     1981 accaaatata ttctcatttg catttgtctt tccaaaagcc aataaaagta tctttcagta
     2041 ttactgtaat catttttttc tttaaatgtt tactctgtta agcttagcaa ataaaatctt
     2101 gttctgttaa
//
