LOCUS       NM_133320               2220 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus nudE neurodevelopment protein 1-like 1 (Ndel1),
            mRNA.
ACCESSION   NM_133320
VERSION     NM_133320.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2220)
  AUTHORS   Gao,F.J., Shi,L., Hines,T., Hebbar,S., Neufeld,K.L. and Smith,D.S.
  TITLE     Insulin signaling regulates a functional interaction between
            adenomatous polyposis coli and cytoplasmic dynein
  JOURNAL   Mol Biol Cell 28 (5), 587-599 (2017)
   PUBMED   28057765
REFERENCE   2  (bases 1 to 2220)
  AUTHORS   Fujiwara,T., Ye,S., Castro-Gomes,T., Winchell,C.G., Andrews,N.W.,
            Voth,D.E., Varughese,K.I., Mackintosh,S.G., Feng,Y., Pavlos,N.,
            Nakamura,T., Manolagas,S.C. and Zhao,H.
  TITLE     PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone
            homeostasis
  JOURNAL   JCI Insight 1 (17), e86330 (2016)
   PUBMED   27777970
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2220)
  AUTHORS   Shao,C.Y., Zhu,J., Xie,Y.J., Wang,Z., Wang,Y.N., Wang,Y., Su,L.D.,
            Zhou,L., Zhou,T.H. and Shen,Y.
  TITLE     Distinct functions of nuclear distribution proteins LIS1, Ndel1 and
            NudCL in regulating axonal mitochondrial transport
  JOURNAL   Traffic 14 (7), 785-797 (2013)
   PUBMED   23551859
  REMARK    GeneRIF: knocking down both Ndel1 and NudCL almost blocked
            retrograde mitochondrial axonal transport.
            Erratum:[Traffic. 2013 Oct;14(10):1105-8]
REFERENCE   4  (bases 1 to 2220)
  AUTHORS   Soares,D.C., Bradshaw,N.J., Zou,J., Kennaway,C.K., Hamilton,R.S.,
            Chen,Z.A., Wear,M.A., Blackburn,E.A., Bramham,J., Bottcher,B.,
            Millar,J.K., Barlow,P.N., Walkinshaw,M.D., Rappsilber,J. and
            Porteous,D.J.
  TITLE     The mitosis and neurodevelopment proteins NDE1 and NDEL1 form
            dimers, tetramers, and polymers with a folded back structure in
            solution
  JOURNAL   J Biol Chem 287 (39), 32381-32393 (2012)
   PUBMED   22843697
REFERENCE   5  (bases 1 to 2220)
  AUTHORS   Wang,L., Li,J., Jia,M., Yue,W., Ruan,Y., Lu,T., Zhang,J., Liu,J.
            and Zhang,D.
  TITLE     No association of polymorphisms in the CDK5, NDEL1, and LIS1 with
            autism in Chinese Han population
  JOURNAL   Psychiatry Res 190 (2-3), 369-371 (2011)
   PUBMED   21890215
  REMARK    GeneRIF: The results did not detect a significant association. It
            indicated that common genetic variations in NDEL1 genes might not
            play a role in the genetic predisposition to autism.
REFERENCE   6  (bases 1 to 2220)
  AUTHORS   Hayashi,M.A., Portaro,F.C., Bastos,M.F., Guerreiro,J.R.,
            Oliveira,V., Gorrao,S.S., Tambourgi,D.V., Sant'Anna,O.A.,
            Whiting,P.J., Camargo,L.M., Konno,K., Brandon,N.J. and Camargo,A.C.
  TITLE     Inhibition of NUDEL (nuclear distribution
            element-like)-oligopeptidase activity by disrupted-in-schizophrenia
            1
  JOURNAL   Proc Natl Acad Sci U S A 102 (10), 3828-3833 (2005)
   PUBMED   15728732
REFERENCE   7  (bases 1 to 2220)
  AUTHORS   Nguyen,M.D., Shu,T., Sanada,K., Lariviere,R.C., Tseng,H.C.,
            Park,S.K., Julien,J.P. and Tsai,L.H.
  TITLE     A NUDEL-dependent mechanism of neurofilament assembly regulates the
            integrity of CNS neurons
  JOURNAL   Nat Cell Biol 6 (7), 595-608 (2004)
   PUBMED   15208636
REFERENCE   8  (bases 1 to 2220)
  AUTHORS   Niethammer,M., Smith,D.S., Ayala,R., Peng,J., Ko,J., Lee,M.S.,
            Morabito,M. and Tsai,L.H.
  TITLE     NUDEL is a novel Cdk5 substrate that associates with LIS1 and
            cytoplasmic dynein
  JOURNAL   Neuron 28 (3), 697-711 (2000)
   PUBMED   11163260
REFERENCE   9  (bases 1 to 2220)
  AUTHORS   Sasaki,S., Shionoya,A., Ishida,M., Gambello,M.J., Yingling,J.,
            Wynshaw-Boris,A. and Hirotsune,S.
  TITLE     A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the
            developing and adult nervous system
  JOURNAL   Neuron 28 (3), 681-696 (2000)
   PUBMED   11163259
REFERENCE   10 (bases 1 to 2220)
  AUTHORS   Efimov,V.P. and Morris,N.R.
  TITLE     The LIS1-related NUDF protein of Aspergillus nidulans interacts
            with the coiled-coil domain of the NUDE/RO11 protein
  JOURNAL   J Cell Biol 150 (3), 681-688 (2000)
   PUBMED   10931877
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 26, 2020 this sequence version replaced NM_133320.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY008298.1, SRR26360186.2931916.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                JAXUCZ010000010.1  54061995-54062035   c
            42-139              JAXUCZ010000010.1  54053271-54053368   c
            140-293             JAXUCZ010000010.1  54051549-54051702   c
            294-442             JAXUCZ010000010.1  54048815-54048963   c
            443-579             JAXUCZ010000010.1  54047693-54047829   c
            580-753             JAXUCZ010000010.1  54043507-54043680   c
            754-845             JAXUCZ010000010.1  54040641-54040732   c
            846-997             JAXUCZ010000010.1  54037142-54037293   c
            998-2220            JAXUCZ010000010.1  54029186-54030408   c
FEATURES             Location/Qualifiers
     source          1..2220
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..2220
                     /gene="Ndel1"
                     /gene_synonym="EOPA; NUDE2; Nudel"
                     /note="nudE neurodevelopment protein 1-like 1"
                     /db_xref="GeneID:170845"
                     /db_xref="RGD:621235"
     exon            1..41
                     /gene="Ndel1"
                     /gene_synonym="EOPA; NUDE2; Nudel"
                     /inference="alignment:Splign:2.1.0"
     exon            42..139
                     /gene="Ndel1"
                     /gene_synonym="EOPA; NUDE2; Nudel"
                     /inference="alignment:Splign:2.1.0"
     CDS             54..1091
                     /gene="Ndel1"
                     /gene_synonym="EOPA; NUDE2; Nudel"
                     /note="protein Nudel; nudE nuclear distribution gene E
                     homolog like 1; nuclear distribution gene E-like homolog
                     1; endooligopeptidase A; LIS1-interacting protein NUDEL;
                     LIS1-interacting protein NUDEL; endooligopeptidase A"
                     /codon_start=1
                     /product="nuclear distribution protein nudE-like 1"
                     /protein_id="NP_579854.1"
                     /db_xref="GeneID:170845"
                     /db_xref="RGD:621235"
                     /translation="MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGS
                     RELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLS
                     QTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEK
                     ESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPA
                     TPVGKGTENSFPSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNF
                     AKDQASRKSYVPGSVNCGVMNSNGPECPRSGRATFFHKGAVNGFDPAPPPPGLGSSRP
                     SSAPGMLPLSV"
     exon            140..293
                     /gene="Ndel1"
                     /gene_synonym="EOPA; NUDE2; Nudel"
                     /inference="alignment:Splign:2.1.0"
     exon            294..442
                     /gene="Ndel1"
                     /gene_synonym="EOPA; NUDE2; Nudel"
                     /inference="alignment:Splign:2.1.0"
     exon            443..579
                     /gene="Ndel1"
                     /gene_synonym="EOPA; NUDE2; Nudel"
                     /inference="alignment:Splign:2.1.0"
     exon            580..753
                     /gene="Ndel1"
                     /gene_synonym="EOPA; NUDE2; Nudel"
                     /inference="alignment:Splign:2.1.0"
     exon            754..845
                     /gene="Ndel1"
                     /gene_synonym="EOPA; NUDE2; Nudel"
                     /inference="alignment:Splign:2.1.0"
     exon            846..997
                     /gene="Ndel1"
                     /gene_synonym="EOPA; NUDE2; Nudel"
                     /inference="alignment:Splign:2.1.0"
     exon            998..2220
                     /gene="Ndel1"
                     /gene_synonym="EOPA; NUDE2; Nudel"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccgagcg gcggcgaaca tgcgcttttg acacattggc ggctttcttg atcatggatg
       61 gtgaagatat accggatttt tcaagtttaa aggaagaaac tgcttattgg aaggaacttt
      121 ccttgaagta taagcaaagc ttccaggaag ctcgggatga gctagttgaa ttccaggaag
      181 gaagcagaga attagaagca gaattggagg cacagttagt acaggctgaa caaagaaata
      241 gagacctgca ggctgataac caaagactga aatacgaagt ggaggcgtta aaggagaaac
      301 tagagcatca gtatgcacag agctataagc aggtctcagt gttagaagat gatttaagtc
      361 agacccgggc cattaaggag caactgcata agtatgtgag agagctggag caggccaatg
      421 atgacctgga gcgagcaaaa cgggcaacaa tagtttcact ggaagacttt gaacaaaggc
      481 taaatcaggc cattgaacga aatgcatttt tagaaagtga acttgatgaa aaggaatctt
      541 tgttggtctc agtacagagg ttaaaggatg aagcaagaga tttaaggcaa gagctagcag
      601 ttcgggaacg gcaacaggaa gtgacccgaa agtctgctcc cagctctcca actctggact
      661 gtgagaagat ggattctgcc gtccaggctt cgctctcctt gcctgcaacg cctgtgggga
      721 aaggcacaga aaacagtttt ccttcaccaa aagctatacc aaatggcttt ggaaccagtc
      781 cactaactcc ttctgctagg atatcagcac taaacatcgt gggagatctc ttgcggaaag
      841 taggggcttt agaatccaag ttagcagctt gcaggaactt tgcaaaagac caagcatccc
      901 gaaaatccta tgttccaggg agcgttaact gtggggtaat gaacagcaac ggtccagagt
      961 gcccaaggtc agggcgtgca actttcttcc ataaaggggc agtaaacggc tttgatccag
     1021 ctcctcctcc tcctgggctg ggctcctcac gcccatcgtc agcaccgggt atgctgcctc
     1081 tcagtgtgtg agtgcccggc ctccaggtgg ggcccctgcc ctcttccagc agcccaggac
     1141 acctacgcct cgtccctcgg tgcctgggtc cagccctgtg cccctctgtc tgcctcttca
     1201 ccgctggcag agggcaggct gcatgcagtg gccgctgctg ggccctgccc agccccagga
     1261 ctctgcgcga tatcaatact ggctattttc tcttctcgcc gtagtgccgt tggtttcaca
     1321 tgattgcact tttgtgggtc ccaagtgata cacacataca tacgtgtgtt tctcgatcac
     1381 tggatgtgga agcacccgtt catcacatct gcctcatagc ccccatattg ctgtgctgat
     1441 aggatttagt tgtgtttagg acattgcaga tcttctagaa gtttccctca atcaggttgg
     1501 taaggccttc taagctcctg ccaagcatct tcagtgctca caatcatgtg tccccagcct
     1561 cacccctgca gtcaggaacg tctctgaatt acggaacact gtctgtacct tctggcttta
     1621 tgtaagcagt ccattccatt gcttgtttct caaagcagcg agatgcctgt ctgagctgca
     1681 agaggcaggg gcagctgaga catgggcact ccagggctga gcctctgtgc tgccctctcc
     1741 tctgtgcctc agactcagga ggcaggtggc agccttcttg ccagctttcc aggccctcag
     1801 gtcagtgaca tctctcagag cggttttgtt tttttttttt tttttcttct cctctgaagg
     1861 gccatcaagt tgcactgggg agggttgagg ggcccgattg tgggctggcg gtgtcagctc
     1921 ttgggcacag actggctaga ggtgtttgtc ccttgcaccc tttggctatt ctcatgctgc
     1981 acttactgtt tacatttgtt ttactgtaca taggtttgta aacattattg cctaagatat
     2041 ttgtatataa cttgggcttt gtagctttta tttattcaga ctcacatggc atgttaatta
     2101 atgacttacg atggtgtccg actctgggca gctggatagg atcatcatgt ggttaacaga
     2161 agatacttcc ctccaaaaaa tcttttaatg tggaaacaat aaatttcaca gaaaacaaaa
//
