LOCUS       NM_001025023            2636 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus NDC1 transmembrane nucleoporin (Ndc1), mRNA.
ACCESSION   NM_001025023 XM_575879
VERSION     NM_001025023.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2636)
  AUTHORS   Akiyama,K., Noguchi,J., Hirose,M., Kajita,S., Katayama,K.,
            Khalaj,M., Tsuji,T., Fairfield,H., Byers,C., Reinholdt,L., Ogura,A.
            and Kunieda,T.
  TITLE     A mutation in the nuclear pore complex gene Tmem48 causes
            gametogenesis defects in skeletal fusions with sterility (sks) mice
  JOURNAL   J Biol Chem 288 (44), 31830-31841 (2013)
   PUBMED   24045954
REFERENCE   2  (bases 1 to 2636)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 2636)
  AUTHORS   Mansfeld,J., Guttinger,S., Hawryluk-Gara,L.A., Pante,N., Mall,M.,
            Galy,V., Haselmann,U., Muhlhausser,P., Wozniak,R.W., Mattaj,I.W.,
            Kutay,U. and Antonin,W.
  TITLE     The conserved transmembrane nucleoporin NDC1 is required for
            nuclear pore complex assembly in vertebrate cells
  JOURNAL   Mol Cell 22 (1), 93-103 (2006)
   PUBMED   16600873
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC079443.1.
            
            On Jun 25, 2005 this sequence version replaced XM_575879.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079443.1, SRR8487231.71268.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2636
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q34"
     gene            1..2636
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /note="NDC1 transmembrane nucleoporin"
                     /db_xref="GeneID:362557"
                     /db_xref="RGD:1560173"
     exon            1..398
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     CDS             339..2360
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /note="transmembrane protein 48"
                     /codon_start=1
                     /product="nucleoporin NDC1"
                     /protein_id="NP_001020194.1"
                     /db_xref="GeneID:362557"
                     /db_xref="RGD:1560173"
                     /translation="MATAASGPCAGGSPRDILWRVLGWRIVTSVVWSVLLLPVCITAF
                     IVFSSIDLFHPIQWLSDSLNEFYSSQVIFYLLLLAVVIIIISIFNVEFYTVVPSIPGS
                     RLALIARILHPQQLTHSFIHAVMGMAVAWCAAIMTKGQSRSLVVPCTGTESLDSPAAQ
                     TCMNEYHLFFLLSGAFMGYSYSLLYFINNMNYLPFPIIQQYKFLRFRRSLLLLVKHSC
                     VESLFMVRNFCIVYYFFGHIPKAWISTALDLRTDEQAHRPLDTIGGLLNVSLLYHVWL
                     CGVFLLMTWYISWILFKIYATEAYMFPVQPPFAEESDECLPKVLNSNPPLIIKYLALQ
                     DLMLLSQYSPSRRQEVFSLSQPGGHPHNWTAISRECLSLLNDMTQKLVLYQEAAATNG
                     RMYSSYSVEPKRLSSPEETAFQTPKPSQMPSVPPLVKTSLFSPKLSTPDGSSPFGTPF
                     GSSVVNRMAGIFDVNTCCGSPQSPQLVRRGPRLWTHTSDQQVSAVSNPSPCASVTAEG
                     KTVRQPSVLYSWIQNKREQIKNFLSKRVLIMYFFSKHPEASIQAVFSDAQMHIWALEG
                     LSHLVAASFTEDRFGVVQTTLPAILNTLLTLQEAVDKYFKLPHASSKPPRTSGSLVDT
                     SYKTLRFAFRASLKTAIYRITTTFGEHLNAVQASAEHQKRLQQFLEFKE"
     exon            399..519
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            520..621
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            622..796
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            797..935
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1044
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1096
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1232
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            1233..1325
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1407
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            1408..1563
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            1564..1803
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..1919
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            1920..1970
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            1971..2034
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            2035..2135
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            2136..2296
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
     exon            2297..2610
                     /gene="Ndc1"
                     /gene_synonym="Tmem48"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caggggtcgt cgagactaca gttcccagca tgcagcaccg tcgccctttg tttttgacgc
       61 cccgatggac cctgcttcgg aaggattttt tggactccag aggacggttc ttcgagtcac
      121 agcccacctg gaggcatgtg gctacgggga agttctggcc ggttgagtct gttcaggcga
      181 agctgcggag agatggcctg gcggttttgc aggactctgt ccaggcagcg ttccgggcag
      241 ccccagctgg gtcctcctgg ggccttcctg cctttgaaca gtggtggcgg gcgggcactc
      301 tgtccccagc acgcttgaga gcgggggccg ccatctccat ggccacggct gcgagcgggc
      361 cctgcgccgg cgggtcaccg cgggacatcc tttggcgcgt tttgggctgg aggatagtta
      421 ctagtgtcgt ttggtcagtg ctgcttctcc ctgtctgcat cacagcattt atagtcttca
      481 gcagcatcga tttattccac cctatacagt ggctgtcaga ttctctcaat gagttctata
      541 gttcccaagt aatcttttac ctcctgctgc tggccgtggt cattataata ataagtattt
      601 tcaatgtgga gttctataca gttgtgccct ccatacccgg ctcccgactg gcgctgatag
      661 cacggatcct tcaccctcag cagctcacgc actccttcat acacgctgtg atgggaatgg
      721 cagtggcttg gtgtgcggcc atcatgacca agggccagtc caggtctctg gtagttccct
      781 gcactggaac ggagagctta gatagccctg ctgctcaaac ctgcatgaat gaatatcatc
      841 tgtttttcct actgtctgga gcattcatgg gctatagcta tagtcttctg tatttcatta
      901 acaacatgaa ttatcttccg tttcctatta tacagcagta caaatttttg cgtttccgga
      961 gatctctcct cttactagtt aaacatagct gtgtggaatc cctgttcatg gtcagaaatt
     1021 tctgcattgt atattatttt tttggtcata ttcccaaagc atggattagc actgctctgg
     1081 accttcgcac agacgagcag gcccacaggc ctcttgacac gataggcggt ctcctgaacg
     1141 tctcattgct ctaccatgtc tggctgtgtg gtgtctttct cttgatgact tggtatatct
     1201 catggatact cttcaaaatc tatgccacag aggcttatat gttccctgtt cagccaccat
     1261 ttgcggaaga atcagatgaa tgccttccta aagtcttaaa tagcaatccc ccactcatca
     1321 taaagtattt ggccttacag gacctgatgt tgctttctca gtattctcct tctcgaaggc
     1381 aagaagtttt cagcctcagc caaccaggtg gacatcccca caattggact gctatttcga
     1441 gggagtgttt gagtctttta aatgatatga ctcagaagct ggttctctac caagaagctg
     1501 ctgctacgaa tgggcggatg tattcctcat actcagtgga acccaagaga ctgagttctc
     1561 cagaagaaac tgcttttcag actccaaaac ctagccagat gccttccgtg ccgccattag
     1621 ttaaaacctc attgttttct ccaaaattaa gtacacctga cggttcaagt ccttttggga
     1681 ctccgtttgg ctccagtgta gtgaaccgaa tggctggaat ttttgatgta aacacctgct
     1741 gtggatctcc ccagagtcct cagcttgtca gaagagggcc gagactgtgg actcacactt
     1801 ctgatcagca agtgtctgca gtctctaatc cctctccttg tgcctctgtc actgctgagg
     1861 gcaagacagt gaggcagccc agtgtgctct actcgtggat tcagaataaa cgggagcaga
     1921 ttaagaattt cttgtcgaaa cgggtgctga taatgtactt tttcagtaag catccagagg
     1981 cctccattca ggctgttttt tcagatgccc aaatgcatat ttgggcttta gaaggtctgt
     2041 ctcacttagt agcagcatca tttacagaag atagatttgg agttgtccag accacgctcc
     2101 cagctatcct taatactttg ctgactctgc aggaggctgt tgacaaatac ttcaagctgc
     2161 cccatgcttc tagtaaacca ccccgaactt caggaagcct cgtggacaca tcctacaaaa
     2221 cattaagatt tgctttcagg gcctcactga aaactgctat ctaccgtata accaccacgt
     2281 ttggtgaaca tctgaatgct gtgcaagcat ctgcagaaca tcagaaaaga cttcaacagt
     2341 tcttggagtt caaagaatag ttaagtaata taaactgtgt tcattaccct gctgatacaa
     2401 ctacagatgg gacagtaaat gttcagcatt cttggatcag aagaaaatgg actaattaga
     2461 tgcttccttt gtcgtggtgc ctgctttgaa aactatactt taatgggaga aatcatggaa
     2521 agaaattctc agcagaataa ccgaaaactg ccttttctgt accaaatgct ttttgtgtgt
     2581 gtggtataat aaaatcttta ttcagtttta aaaaaaaaaa aaaaaaaaaa aaaaaa
//
