LOCUS       NP_001014104             563 aa            linear   ROD 02-JUN-2024
DEFINITION  BOS complex subunit NCLN precursor [Rattus norvegicus].
ACCESSION   NP_001014104 XP_234929
VERSION     NP_001014104.1
DBSOURCE    REFSEQ: accession NM_001014082.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 563)
  AUTHORS   Dettmer,U., Kuhn,P.H., Abou-Ajram,C., Lichtenthaler,S.F.,
            Kruger,M., Kremmer,E., Haass,C. and Haffner,C.
  TITLE     Transmembrane protein 147 (TMEM147) is a novel component of the
            Nicalin-NOMO protein complex
  JOURNAL   J Biol Chem 285 (34), 26174-26181 (2010)
   PUBMED   20538592
REFERENCE   2  (residues 1 to 563)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083785.1.
            
            On Apr 20, 2005 this sequence version replaced XP_234929.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083785.1, SRR8487231.48847.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..563
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     Protein         1..563
                     /product="BOS complex subunit NCLN precursor"
                     /note="nicastrin-like protein; nicalin homolog; BOS
                     complex subunit NCLN"
                     /calculated_mol_wt=58665
     sig_peptide     1..42
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=4345
     mat_peptide     43..563
                     /product="BOS complex subunit NCLN. /id=PRO_0000019689"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5XIA1.1)"
                     /calculated_mol_wt=58665
     Region          127..429
                     /region_name="M28_nicalin_like"
                     /note="M28 Zn-Peptidase Nicalin, Nicastrin-like protein;
                     cd03882"
                     /db_xref="CDD:349878"
     Site            241
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q5XIA1.1)"
     Site            428
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q5XIA1.1)"
     Site            523..543
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5XIA1.1)"
     CDS             1..563
                     /gene="Ncln"
                     /gene_synonym="RGD1309355"
                     /coded_by="NM_001014082.1:82..1773"
                     /db_xref="GeneID:314648"
                     /db_xref="RGD:1309355"
ORIGIN      
        1 mleeagevle nvlkasclpl gfivflpavl llvapplpaa daaheftvyr mqqydlqgqp
       61 ygtrnavlnt eartvdadvl srrcvlmrll dfsyehyqka lrqsagavvi ilpramaavp
      121 qdvvrqfmei epemlametv vpvyfavede allsiyeqtq aasasqgsas aaevllhtat
      181 angfqmvtsg aqsqavsdwl itsvegrltg lggedlptiv ivahydafgv apwlslgads
      241 ngsgisvlle larlfsrlyt ykrthaaynl lffasgggkf nyqgtkrwle dsldhtdssl
      301 lqdnvafvlc ldtvgrgshl rlhvskppre gtlqhvflre lemvaahqfp dvsfsmvhkk
      361 inladdvlaw eherfairrl paftlshlen hragprssim dvrsrvdskt ltrntriiae
      421 altrviynlt ekgtppdmpv fteqmqvqqe qidsvmdwlt nqpraaqlld kdgtflstle
      481 hflsrylkdv rqhhvkadkr dpefvfydql kqvmnayrvk paifdlllal cigaylgmay
      541 tavqhfhvly ktvqrlllka kaq
//
