LOCUS       NM_001034000            5185 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus non-SMC condensin II complex, subunit D3
            (Ncapd3), mRNA.
ACCESSION   NM_001034000 XM_235955 XM_343512
VERSION     NM_001034000.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5185)
  AUTHORS   Martin,C.A., Murray,J.E., Carroll,P., Leitch,A., Mackenzie,K.J.,
            Halachev,M., Fetit,A.E., Keith,C., Bicknell,L.S., Fluteau,A.,
            Gautier,P., Hall,E.A., Joss,S., Soares,G., Silva,J., Bober,M.B.,
            Duker,A., Wise,C.A., Quigley,A.J., Phadke,S.R., Wood,A.J.,
            Vagnarelli,P. and Jackson,A.P.
  CONSRTM   Deciphering Developmental Disorders Study
  TITLE     Mutations in genes encoding condensin complex proteins cause
            microcephaly through decatenation failure at mitosis
  JOURNAL   Genes Dev 30 (19), 2158-2172 (2016)
   PUBMED   27737959
  REMARK    Erratum:[Genes Dev. 2017 May 1;31(9):953. PMID: 28566537]
REFERENCE   2  (bases 1 to 5185)
  AUTHORS   Lee,J., Ogushi,S., Saitou,M. and Hirano,T.
  TITLE     Condensins I and II are essential for construction of bivalent
            chromosomes in mouse oocytes
  JOURNAL   Mol Biol Cell 22 (18), 3465-3477 (2011)
   PUBMED   21795393
REFERENCE   3  (bases 1 to 5185)
  AUTHORS   Liu,W., Tanasa,B., Tyurina,O.V., Zhou,T.Y., Gassmann,R., Liu,W.T.,
            Ohgi,K.A., Benner,C., Garcia-Bassets,I., Aggarwal,A.K., Desai,A.,
            Dorrestein,P.C., Glass,C.K. and Rosenfeld,M.G.
  TITLE     PHF8 mediates histone H4 lysine 20 demethylation events involved in
            cell cycle progression
  JOURNAL   Nature 466 (7305), 508-512 (2010)
   PUBMED   20622854
REFERENCE   4  (bases 1 to 5185)
  AUTHORS   Manning,A.L., Longworth,M.S. and Dyson,N.J.
  TITLE     Loss of pRB causes centromere dysfunction and chromosomal
            instability
  JOURNAL   Genes Dev 24 (13), 1364-1376 (2010)
   PUBMED   20551165
REFERENCE   5  (bases 1 to 5185)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   6  (bases 1 to 5185)
  AUTHORS   Ono,T., Losada,A., Hirano,M., Myers,M.P., Neuwald,A.F. and
            Hirano,T.
  TITLE     Differential contributions of condensin I and condensin II to
            mitotic chromosome architecture in vertebrate cells
  JOURNAL   Cell 115 (1), 109-121 (2003)
   PUBMED   14532007
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC101928.1.
            
            On or before Oct 9, 2005 this sequence version replaced
            XM_235955.3, XM_343512.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC101928.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132265, SAMD00155310
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5185
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..5185
                     /gene="Ncapd3"
                     /note="non-SMC condensin II complex, subunit D3"
                     /db_xref="GeneID:315508"
                     /db_xref="RGD:1562176"
     exon            1..63
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            64..246
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..4670
                     /gene="Ncapd3"
                     /codon_start=1
                     /product="condensin-2 complex subunit D3"
                     /protein_id="NP_001029172.1"
                     /db_xref="GeneID:315508"
                     /db_xref="RGD:1562176"
                     /translation="MALKDLGRDLQPWCPLDLSLEWVNTVWDLDFTETEPLDPSVVAE
                     ILETGRDAFTKLYGSLFPFATDESGSLESVWSFFTENSISSNTLVALFCHFVQEAHKK
                     SASVQYREYGLRAAGLYFLLLEIPGSVVNQVFHPVMFDKCIQILKKSWPQESNLTQKR
                     KKEHSKSSKANYRRSRKRGKPPRKEDYQVDELSREEEEEEEEEIYFSVRDLSQIRDAI
                     FNLLKNFLRLLPKFSLKEKPQSIQTCIEVFVALTSFEPIPHKFLISQARNLSEVKHIS
                     ELAYYGLYLLCSPVHGEGNKVIGSIFHQMLNVILMLEVGEGSRCAPLAITSHVINCRN
                     QAVQFVSSLVDELQESVFPILGTLLQHICAKVVDKAEYRTYAAQSLVQLLSKLPSKEY
                     ATFIAWLYKYSRSSKIPHRVFTLDVALALLELPERLLDDTVLLEHQKFLKHKFFVQEI
                     IFDRCLDKAPTVRSKALSSFAQCLELSTSNTSENTLEIFINSTVTGIHSHFGTSLRPS
                     TVLTSQSCRSVQSSTHDSDEQTPPGERRFMTMLRKRTKDEKINVRKSALQVLMSILKH
                     CDILSMEEDLLILQDHCRDPAISVRKQALQSLTELVMAKPTCVPVQKAWLMGVIPVVM
                     DYESTVQEKALECLDQLLLQNIKHHRKFHSEDRSQVLAWALLALLTVESQDLSRYLNK
                     AFHIWSKKDKFSSTFINSVISHTDTERSAPAWMLLSKITCSSPKLDYTKIMESWEKLS
                     REQSPNSNTLGYMLCVIGHIAKHLPKSTQDKITGVIKAKLNGFQWSLELISLSVDTLQ
                     GLCRASAKTLREEQELLKRVCGDVLSTCEQHLSNILLKEDGTGNMDEDLVVKCIFTLG
                     DIAQLCPALVEKRVFLLIQSILASSAHADHLPSSQGTTDLASQLPFQARSSALPSVIR
                     AHAIITLGKLCLQHEDLAKKSIPALVRELEVCEDVAVRNNVIIVMCDLCIRYTVMVDN
                     YIPNISICLKDSDPFIRKQTLILLTNLLQEEYVKWKGSLFFRFVSTLVDSHPDIASLG
                     EFCLAHLLLKRNPTMFFQHFIECIFHFNSYEKHGQYNKFSQSERGKPLFLLKGKTNKE
                     KRMRIYKFLLEHFTDEQRFNVTSKICLNILACFTDGVLPVDMEASELLSDTFDILSSK
                     EIKLLAMRAQASKELLEEDDVALANVVMQEAQMKIISQVQKRNFIENIIPIIISLKTV
                     LEKNKIPALRELMNYLREVMQDYRDEIKDFFAVDRQLASELEYDMKKYTEQLAQEQAL
                     TEHANATNVPADGDRVPSQQVAPDLQAVPGAAAAAGAGQADANMPLPLAQSQPSAPGS
                     SFTPTLPPICEKGPLKIMSSTRPMSLSTIAILNSVKKAVASKSRTRSLGALSFNMENG
                     SPENPSSRASSLSLEQESERAVKRVTKRAISTPEKSISNVTFGAGVSYIGTPATSFFT
                     KEKPEEAQEEGNDILCLSLLDKRPPQSPQWNVKSPARSQDNPRSGRRSLRKAPLKTAN
                     "
     exon            247..401
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            402..564
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            565..749
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            750..923
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            924..985
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1073
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1074..1207
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..1280
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1281..1406
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1407..1659
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1660..1713
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1714..1785
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1786..1859
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1860..1994
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1995..2215
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            2216..2407
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            2408..2505
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            2506..2621
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            2622..2729
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            2730..2844
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            2845..2949
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            2950..3188
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            3189..3268
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            3269..3406
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            3407..3540
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            3541..3737
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            3738..3848
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            3849..4031
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            4032..4210
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            4211..4344
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            4345..4422
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            4423..4497
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            4498..4561
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
     exon            4562..5149
                     /gene="Ncapd3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggtcctggc ctctttccac cagaactcgg gcccagatgt tccgtaaagt cttagcacta
       61 caggttgcaa actcggctca gcgcggtgat tggtcgattg caaatcccga acgttgtgac
      121 tggttcgcag aaacgtctct gtgcgcgcgc gggaacgact gcgagccggt acgtctatgg
      181 tcggaatggc gctgaaggat ctaggaagag acctgcagcc ttggtgtccg ctggatctca
      241 gccttgaatg ggtgaacaca gtgtgggacc tggacttcac ggagaccgaa cctttggatc
      301 ccagcgtggt agcagagatc ctagagactg gaagagatgc gttcacaaag ctctatggga
      361 gcctcttccc ctttgcaacc gacgaaagtg gctctttaga gagcgtctgg tccttcttca
      421 ctgagaacag catttccagc aacactctgg tggcgttgtt ctgtcacttt gtccaggaag
      481 cccataaaaa aagtgccagt gtgcaatatc gagaatatgg ccttcgtgct gcggggctct
      541 atttcctgct gctagaaata ccaggcagcg tagtcaatca agtattccac ccagtgatgt
      601 tcgacaagtg tattcagatc ctgaagaaga gctggcctca agaatccaac ttgactcaga
      661 agagaaaaaa ggaacactcc aagagttcta aggctaatta caggaggagc agaaaaagag
      721 gaaaaccacc taggaaagag gattatcagg tggatgaact ttcaagagag gaagaggagg
      781 aggaggaaga ggagatttat ttttctgtcc gggacctttc tcaaatacga gatgccatat
      841 ttaatcttct aaagaatttt ttaaggcttc tgcccaagtt ttctcttaaa gaaaagccgc
      901 agtctattca aacatgtata gaggtgtttg ttgcattaac tagttttgaa ccaattcctc
      961 ataaatttct tatttcacaa gccaggaacc tcagtgaagt aaaacacatt tcagagctgg
     1021 cctactatgg attgtacttg ctgtgctccc cagttcatgg agaaggaaat aaggttatcg
     1081 gttctatttt tcatcaaatg ctcaatgtga tactgatgtt agaggtagga gaagggtccc
     1141 gctgtgctcc tcttgccata acctcacacg tcatcaattg tagaaaccaa gcagtccagt
     1201 ttgtcagctc acttgtggat gaactacaag aaagtgtgtt ccccatcctt ggtactttac
     1261 tgcagcacat ctgtgccaag gtggtggata aagcagaata tcggacctac gcagcacagt
     1321 ccctggtcca gctgcttagc aaacttccct ccaaggaata tgctacattc attgcctggc
     1381 tttacaaata ttcacgaagt tccaagatcc cacaccgggt cttcactctt gatgttgctt
     1441 tagctctgtt agagctgccc gaaagactgc tggatgacac tgtgctactg gagcatcaga
     1501 agtttctaaa gcataaattc tttgtgcaag aaattatatt tgatcgttgc ttagataagg
     1561 cacctactgt ccgcagcaag gcgctgtcca gctttgcaca gtgtttggag ttgtctacta
     1621 gcaacacatc tgagaacaca ctggaaatct tcattaacag tactgtgaca ggaatacaca
     1681 gtcactttgg cacctcactg agaccctcga cagtgttaac cagccaaagt tgccgctcag
     1741 tacaaagcag cacccatgac agtgatgaac agactccgcc tggagagaga cgcttcatga
     1801 caatgctgag aaaaagaacc aaagatgaga agatcaacgt taggaagtct gcactccagg
     1861 tgttaatgag tattttgaaa cactgtgaca tcttgagcat ggaggaggac ctgttgatcc
     1921 tgcaggacca ctgtcgagac cctgccatat ctgtgcggaa gcaagcccta cagtctctta
     1981 cagaacttgt catggccaag cctacttgtg tcccagtgca gaaggcctgg ctgatgggtg
     2041 tcatccctgt ggtgatggac tatgagagca cagtgcaaga gaaggccttg gagtgcctgg
     2101 accagctcct gctgcagaac attaagcacc ataggaagtt tcacagcgag gacaggagtc
     2161 aggtgctcgc ctgggcccta cttgctctcc tcaccgtaga aagccaagat ctgagccgct
     2221 atttaaataa ggcttttcat atctggtcca agaaagataa attctcatcc acttttataa
     2281 acagtgtgat atcccacact gacacagaac gttctgcgcc agcctggatg ctgctctcca
     2341 agatcacttg ctcgtcaccc aagctggact ataccaaaat aatggagtcg tgggagaaac
     2401 tcagcagaga acaatctccc aactcaaaca ccttaggcta catgctgtgt gtcattgggc
     2461 atattgcaaa gcatcttcca aagagcacac aggacaagat aactggtgtg atcaaggcca
     2521 agctgaatgg atttcagtgg tctctagagc tgatcagttt gtccgttgac acattacaag
     2581 ggctttgcag agcatctgca aagacactgc gggaagagca ggaactgctg aagcgggtgt
     2641 gtggggatgt cctctccacc tgtgagcaac acctctctaa catccttctg aaggaagacg
     2701 ggacagggaa catggatgaa gacctggtgg tgaaatgcat ttttacccta ggagatatag
     2761 cccagttatg tccagcccta gtagagaagc gagtcttcct tctaatccag tctattctgg
     2821 cttcttctgc tcatgcggat cacttgccat catctcaagg gaccacagac ctcgccagtc
     2881 agctgccttt ccaggccagg agctctgccc tgccgtctgt gattagagca catgccatca
     2941 tcactctggg taaactctgc ttacagcatg aagaccttgc aaagaaaagc atcccagccc
     3001 ttgtgcgaga acttgaagtc tgtgaggatg tggctgtccg caacaatgtc atcattgtga
     3061 tgtgtgatct ttgtatccgg tacactgtca tggtggacaa ttatattccc aatatttcca
     3121 tttgcctgaa ggattcagac ccgttcatcc gaaagcagac actgatcttg cttaccaacc
     3181 tcttacagga ggaatatgtg aagtggaagg gctctctgtt cttccgattt gtcagcactc
     3241 tggtagactc acacccagac attgccagcc ttggggagtt ctgcctggct cacttgttgc
     3301 tgaagaggaa ccctaccatg tttttccagc acttcattga gtgcatattc cacttcaaca
     3361 gctatgagaa gcatgggcag tataacaagt tttcccagtc ggagaggggg aagccactgt
     3421 ttttgctaaa gggaaagaca aacaaggaga agcgaatgag aatctacaag tttcttcttg
     3481 agcacttcac agatgagcag cgattcaatg tcacttccaa gatctgtctt aacattttgg
     3541 cgtgcttcac ggatggcgtc ctgcccgtgg acatggaagc cagcgagctg ctctccgata
     3601 cctttgacat cctcagctct aaggagatca aactattggc aatgagagcg caggcatcca
     3661 aggagctcct ggaggaagat gacgtggctc tggcgaatgt ggtcatgcag gaggcccaga
     3721 tgaagattat ctcgcaggtt caaaagagga atttcataga gaatattatt ccaatcatca
     3781 tctccctgaa gactgtgctg gagaaaaata agatccctgc tttaagggaa ctcatgaact
     3841 acctcaggga agtaatgcag gattaccgcg atgagatcaa agacttcttt gcagtggaca
     3901 gacagctggc gtctgagctt gagtatgaca tgaagaagta cactgaacaa ctggcccagg
     3961 agcaagctct gacggagcat gctaatgcca ccaacgtgcc tgcagacggg gacagggtcc
     4021 cctcccagca ggttgctcca gacttacaag ctgtacctgg cgctgctgcc gccgctggtg
     4081 ctggccaggc cgatgctaac atgcctctgc ctctggccca gagccagcct tcagcacctg
     4141 ggtccagctt cacaccaact ttgcctccta tatgcgaaaa gggacctctg aagataatgt
     4201 ccagtaccag gcccatgtct ctgagtacca tcgcaatcct gaattcagtc aagaaagctg
     4261 ttgcgtctaa gagcaggaca cgcagtttag gagccctgtc tttcaacatg gagaacggaa
     4321 gcccagaaaa tccctccagc cgtgcgtctt ccttgagctt ggagcaggag tctgagagag
     4381 ccgtcaagcg tgtgactaaa agggcgatca gcaccccaga gaagtccatc agcaatgtca
     4441 catttggagc aggggtcagt tacataggga caccagcaac ttcgtttttt accaaagaga
     4501 aacctgaaga agcccaggaa gaaggaaatg acattttatg tttgtcattg cttgataaaa
     4561 ggcctccgca gtctccacag tggaatgtga agtctccagc caggagccaa gacaaccccc
     4621 ggtccggcag aaggtccctt cgcaaggccc cgctgaagac agccaactga gacctgcggg
     4681 gatatctgcc ttccccgtgt gtgtgcaagg aggaaagatg gtgtggcctg cacccacaca
     4741 ggagagaccc gctgcgccct gccaactcct gtctaggaca ccaatgcaac tttgtgcagc
     4801 ttgtatctct ccttgtgtgc atcatcgttg ttgagatttg taaatagaga catgatgtat
     4861 ttagactttc tcacaataac attaagctat ttaatactgt gatgttctat ttgagtatca
     4921 aaccttctgt ggtaagttac actctggtct ttaaggaaca cgattttaga aaccagcttt
     4981 cttctgtgta acataagtgt ctatagtttg tgtgaattca atataataga tatgtcccct
     5041 tagctaatgg caaaattttg aatatttttc tattatttat aattgcaaat ttgtattaaa
     5101 agagatgtac agtctttcta aaacaaataa aggtcaaata taaatgtaaa aaaaaaaaaa
     5161 aaaaaaaaaa aaaaaaaaaa aaaaa
//
