LOCUS       NM_001399442            4565 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus non-SMC condensin I complex, subunit D2 (Ncapd2),
            mRNA.
ACCESSION   NM_001399442 XM_039108812
VERSION     NM_001399442.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4565)
  AUTHORS   Martin CA, Murray JE, Carroll P, Leitch A, Mackenzie KJ, Halachev
            M, Fetit AE, Keith C, Bicknell LS, Fluteau A, Gautier P, Hall EA,
            Joss S, Soares G, Silva J, Bober MB, Duker A, Wise CA, Quigley AJ,
            Phadke SR, Wood AJ, Vagnarelli P and Jackson AP.
  CONSRTM   Deciphering Developmental Disorders Study
  TITLE     Mutations in genes encoding condensin complex proteins cause
            microcephaly through decatenation failure at mitosis
  JOURNAL   Genes Dev 30 (19), 2158-2172 (2016)
   PUBMED   27737959
  REMARK    Erratum:[Genes Dev. 2017 May 1;31(9):953. PMID: 28566537]
REFERENCE   2  (bases 1 to 4565)
  AUTHORS   Lee J, Ogushi S, Saitou M and Hirano T.
  TITLE     Condensins I and II are essential for construction of bivalent
            chromosomes in mouse oocytes
  JOURNAL   Mol Biol Cell 22 (18), 3465-3477 (2011)
   PUBMED   21795393
REFERENCE   3  (bases 1 to 4565)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 4565)
  AUTHORS   Ball AR Jr, Schmiesing JA, Zhou C, Gregson HC, Okada Y, Doi T and
            Yokomori K.
  TITLE     Identification of a chromosome-targeting domain in the human
            condensin subunit CNAP1/hCAP-D2/Eg7
  JOURNAL   Mol Cell Biol 22 (16), 5769-5781 (2002)
   PUBMED   12138188
REFERENCE   5  (bases 1 to 4565)
  AUTHORS   Bomar J, Moreira P, Balise JJ and Collas P.
  TITLE     Differential regulation of maternal and paternal chromosome
            condensation in mitotic zygotes
  JOURNAL   J Cell Sci 115 (Pt 14), 2931-2940 (2002)
   PUBMED   12082153
REFERENCE   6  (bases 1 to 4565)
  AUTHORS   Kimura K, Cuvier O and Hirano T.
  TITLE     Chromosome condensation by a human condensin complex in Xenopus egg
            extracts
  JOURNAL   J Biol Chem 276 (8), 5417-5420 (2001)
   PUBMED   11136719
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000150.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001399442.2.
            
            On Jan 7, 2022 this sequence version replaced XM_039108812.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ226121.1, FQ231221.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-141               JACYVU010000150.1  790447-790587       c
            142-287             JACYVU010000150.1  789317-789462       c
            288-363             JACYVU010000150.1  786163-786238       c
            364-422             JACYVU010000150.1  785834-785892       c
            423-604             JACYVU010000150.1  785180-785361       c
            605-747             JACYVU010000150.1  784777-784919       c
            748-875             JACYVU010000150.1  783199-783326       c
            876-999             JACYVU010000150.1  783002-783125       c
            1000-1147           JACYVU010000150.1  782673-782820       c
            1148-1345           JACYVU010000150.1  780103-780300       c
            1346-1480           JACYVU010000150.1  779079-779213       c
            1481-1568           JACYVU010000150.1  778897-778984       c
            1569-1743           JACYVU010000150.1  778648-778822       c
            1744-1859           JACYVU010000150.1  777260-777375       c
            1860-2084           JACYVU010000150.1  776770-776994       c
            2085-2259           JACYVU010000150.1  776023-776197       c
            2260-2344           JACYVU010000150.1  775702-775786       c
            2345-2478           JACYVU010000150.1  774226-774359       c
            2479-2611           JACYVU010000150.1  773780-773912       c
            2612-2696           JACYVU010000150.1  773601-773685       c
            2697-2861           JACYVU010000150.1  773359-773523       c
            2862-3034           JACYVU010000150.1  773000-773172       c
            3035-3146           JACYVU010000150.1  771724-771835       c
            3147-3270           JACYVU010000150.1  771526-771649       c
            3271-3426           JACYVU010000150.1  771289-771444       c
            3427-3604           JACYVU010000150.1  770755-770932       c
            3605-3699           JACYVU010000150.1  770570-770664       c
            3700-3780           JACYVU010000150.1  769828-769908       c
            3781-3964           JACYVU010000150.1  769535-769718       c
            3965-4100           JACYVU010000150.1  768472-768607       c
            4101-4256           JACYVU010000150.1  768217-768372       c
            4257-4565           JACYVU010000150.1  767698-768006       c
FEATURES             Location/Qualifiers
     source          1..4565
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..4565
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /note="non-SMC condensin I complex, subunit D2"
                     /db_xref="GeneID:362438"
                     /db_xref="RGD:1562596"
     exon            1..141
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            142..287
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     CDS             161..4342
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /codon_start=1
                     /product="condensin complex subunit 1"
                     /protein_id="NP_001386371.1"
                     /db_xref="GeneID:362438"
                     /db_xref="RGD:1562596"
                     /translation="MSPHNFEFHLPLSPEELLKSRGVNQYVVQEVLPIKHLPTQLRAF
                     QSAFRAQGPLAILDHFDTIYSIIHHFRSIEPGLKEDTLEFLMKVVSCHSQELSSILDD
                     AALSGSDRSAHLNALKMNCYALIRLLESFENMTSQTGLIDLDIGGKGKKARAKTALGF
                     VWEEERQPVLELLTQLLQLDIRHLWSHSVIEEEFVSLVTGCCYRLLENPTISHQKNRS
                     TKEAIAHLLGVALVRYNHMLSATVKIIQMLQHFEHLPSVLVAAVTLWATDYGMKSIVG
                     EIVREIGQKCPQEMSRDTAGAKGFAAFLTELAERIPAALMSSMCMLLDHLDGENYMMR
                     NAVLAAMAEMILQVLNGDQLEESARETRDQFLDILQAHGHDVNSFVRSRVLQLFTRIV
                     QQKALPLTRFQAVVALAVGRLADKSVLVCKNAIQLLASFLANNPFSCKLSDTDLAGPL
                     QKEIQKLQEMRAQRRTAAASAALDSEEEWEAMLPELKSTVQQLLKLPQEEAEQQIADG
                     ETAEEVKGRIHQLLARASYKQAILLTREATSRFQESEPFSHTEPEEKDFLNLLGVIFK
                     GPEASTHESPRHTDPGLTGSKDSPSVPEPEGSQRDDELLKQEMLVQYLQDAYSFSQKI
                     TEAIGVISKMMYENTTTVVQEVIEFFVMVFQFGVPQALFGVRRMLPLIWSKELGVREA
                     VLNAYRQLYLSPKGDSARATAQALIQNLSLLLVDASVGTIQCLEEILCEFVQKDEIKP
                     AVIQLLWERATEKVPCSPLERCSSVMLLGMMARGKPEIVGSNLDTLVKVGLDEKFPQD
                     YRLAQQVCLAIANISDRRKPSLGERHPPFRLPQEHKLFERLQEMVTKGFAHPDPFWIP
                     FKEVAVTLTYQLAEGPDVICSQMLQGCAKQALEKLEKNTTEGDSKETAPKLPTFLLMN
                     LLSLAGDVALQQLVHLEQAVSGELGRRRVLREEQEHRTKVPKEKTTSSETTMEEELGL
                     VGATADDTEAELVRSICEKELLDGTQVLAAFVPLLLKVCNNPGAYSNPELSAAASLAL
                     GKFCMISAPFCDSQLRLLFTMLEKSSLPTVRSNLMVATGDLAIRFPNLVDPWTPHLYA
                     RLRDPAQQVRRTAGLVMTHLILKDMVKVKGQVSEMAVLLIDPVPQIAALAKNFFNELS
                     HKGNAIYNLLPDIISRLSDPEGGVGEEPFHTIMKQLLSYITKDKQTESLVEKLCQRFR
                     TARTERQYRDLAYCVSQLPLTERGLHKMLDNFDCFGDKLIDESVFSAFLSIVGKLRRG
                     AKPEGKAVIDEFEQKLRACHTRGMDGIEELETGQGGSQRALSAKKPSAGVRVSRQQPL
                     TSVDSDNDFVTPKPRRTKPRRPQTQQRKSQRKAKVVFSSDESSEDELSAEMTEEETPK
                     KTTPIRRASAQRHRS"
     exon            288..363
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            364..422
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            423..604
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            605..747
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            748..875
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            876..999
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1147
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            1148..1345
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            1346..1480
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1568
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            1569..1743
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            1744..1859
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            1860..2084
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            2085..2259
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            2260..2344
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            2345..2478
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            2479..2611
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            2612..2696
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            2697..2861
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            2862..3034
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            3035..3146
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            3147..3270
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            3271..3426
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            3427..3604
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            3605..3699
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            3700..3780
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            3781..3964
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            3965..4100
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            4101..4256
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
     exon            4257..4565
                     /gene="Ncapd2"
                     /gene_synonym="RGD1562596"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggattggc tggtttctcc gccagcttga aaaccttctc gctgtttggc gcgtattgtt
       61 ctctagtgtt ttcttccttc cttttcagcg ggggatctcc agttgaagaa gcggcgggtg
      121 aggggtgtcg gaggtgttca ggtaaaccag tgggagaaag atgtctcccc acaactttga
      181 gttccacctg cccttatctc cagaggagct gctgaaaagt agaggtgtga atcagtatgt
      241 tgttcaggag gtactaccca tcaagcatct tccaacccag cttagagcat ttcagtctgc
      301 cttccgagct caggggcccc tggccatact ggaccacttc gatacaatct acagcattat
      361 acatcacttt cgaagtatag aacctggcct caaggaagac accctggaat tcctgatgaa
      421 agtggtatcc tgccactccc aggaactgtc atccatcctg gatgacgcag ctttgagtgg
      481 atcagataga agcgcccacc taaatgccct caaaatgaac tgctatgccc tgatacgcct
      541 cttggagtcc tttgagaata tgaccagcca gacaggcctc attgacctgg acattggtgg
      601 gaagggtaag aaagcccggg ccaaaacagc tcttggcttt gtctgggagg aagagaggca
      661 accagtcctt gagcttttaa cacagctgct ccagctggac attcgtcact tgtggagcca
      721 ctcggtaatt gaagaggaat ttgtcagttt ggttactggc tgttgctacc gcctgttgga
      781 gaatcccacc attagccacc agaagaaccg ctccaccaag gaggccatag cacacctgct
      841 tggggtggcc ttggtccgct acaaccatat gctcagtgcg accgtgaaga tcatccagat
      901 gctacagcac tttgagcacc tgccctctgt cctggtggca gctgtgactc tgtgggcaac
      961 ggattacgga atgaagagca tagtgggaga gatcgtaaga gagattggac agaagtgtcc
     1021 acaggagatg agtcgagaca cagcaggggc aaagggcttt gctgctttcc tcactgagct
     1081 ggcagagcga atcccagctg ccctgatgtc cagcatgtgc atgttgctag atcatctgga
     1141 tggagagaat tatatgatgc gcaatgctgt gttagcagct atggccgaga tgatactcca
     1201 ggttctaaat ggtgaccaat tagaagaatc ggcccgagaa accagagatc agttcttgga
     1261 catcttgcaa gctcatgggc atgatgtgaa ctcctttgtt cgaagccgtg ttttacaact
     1321 ctttacccga attgtccaac aaaaggcgct ccccctgacc cgtttccagg cagtggtggc
     1381 cttagcagtg ggacgtctgg cagacaagtc ggtgctggtg tgtaaaaatg cgattcagct
     1441 gctggccagc tttctagcca acaatccctt ttcctgcaag cttagtgata ccgaccttgc
     1501 tgggccactg cagaaggaga ttcagaagtt acaagaaatg agagcccaga ggcggactgc
     1561 agctgcgtct gcagcactag actcagagga agaatgggag gccatgttgc cagaactgaa
     1621 gtctactgtg cagcagcttc tgaagcttcc ccaagaagag gcagagcagc agattgccga
     1681 tggagagact gcggaggaag tgaaaggacg catccaccaa ctgcttgcca gagctagtta
     1741 caaacaggcc attcttctca ctcgagaagc taccagtcgc ttccaggagt ctgaaccctt
     1801 cagtcacaca gagccagagg agaaggactt cctgaatctc ttgggtgtca tcttcaaagg
     1861 ccctgaagct tccacacacg aatctcctag gcacacagat ccagggctaa ctggcagtaa
     1921 agactctcct agtgtgcctg agcctgaggg gtcccagagg gacgatgagc tgctgaagca
     1981 ggagatgctg gtgcagtacc tgcaggatgc ctacagcttc tcccagaaga tcacagaagc
     2041 cattggcgtc atcagcaaga tgatgtatga gaacacaact acagtggtgc aggaggtgat
     2101 tgagttcttt gtgatggtat tccaatttgg ggtaccccag gccctgtttg gggtacgccg
     2161 catgctgcct ctcatctggt ctaaggagct tggtgtccgg gaagctgtcc ttaatgcata
     2221 ccgccaactg tacctcagcc cgaaagggga ctcagccaga gccacagcgc aggccttgat
     2281 tcagaacctc tcgttgctgt tagtagatgc ctccgtcggg accattcagt gtcttgaaga
     2341 aattctttgt gagtttgtgc agaaggatga gataaagcca gcagtgatcc agctgctgtg
     2401 ggaacgggca acggagaagg tcccgtgctc tcctctggag cgctgttcct ctgtcatgct
     2461 tcttggcatg atggcacgag gaaaaccaga aattgtagga agcaacttag acaccctggt
     2521 gaaggtaggg ctggatgaga agtttccaca ggactacagg ctggcccagc aggtgtgcct
     2581 cgccattgcc aacatctcgg acaggaggaa gccttccctg ggtgaacgtc accctccctt
     2641 ccggctgcct caggagcaca agttgtttga acgacttcag gagatggtca caaagggctt
     2701 tgcacaccca gatcccttct ggatcccatt caaagaggtg gcagtgaccc tgacttacca
     2761 attggcagag gggcctgacg tgatctgttc ccagatgctg caaggctgtg caaagcaagc
     2821 cttggagaaa cttgagaaga ataccactga gggggactcc aaggaaacag cccctaagct
     2881 ccccacgttc ctgctgatga acctgctctc cctggctggg gatgtggccc tacagcagct
     2941 ggtccatttg gaacaggctg tgagcggaga gctgggtcgg cggcgagttc ttcgagagga
     3001 gcaggagcac aggaccaagg tccccaagga gaagaccaca agctctgaaa caacaatgga
     3061 ggaagaactg gggctggtgg gggccactgc tgatgacacg gaggcggagc tcgtccggag
     3121 catctgtgag aaggaactgt tggatggcac tcaggtactc gctgcctttg ttccactgct
     3181 gcttaaagtc tgcaacaacc ctggggcata cagcaaccca gagctctctg cagctgcttc
     3241 tctggccctt ggcaagttct gcatgatcag tgcccctttc tgcgactccc agctccgtct
     3301 tctgttcacc atgcttgaga agtcttcact gcccactgtg cggtctaacc tcatggttgc
     3361 cactggggat ctggctatcc gcttccctaa cctggtggat ccctggactc cccatctata
     3421 tgcccgcctc cgagatccag ctcagcaggt gcggaggaca gcggggctgg tgatgacgca
     3481 cctgatcctg aaggacatgg tgaaagtgaa gggacaggtg agcgagatgg ccgtgctgct
     3541 cattgaccct gtgcctcaga ttgctgcctt ggccaagaat ttcttcaatg agctctccca
     3601 caagggcaat gcaatctata atctcctccc tgatatcatc agtcgcctgt cagacccaga
     3661 gggtggagtg ggggaggagc ccttccacac catcatgaag cagctcctct cctacatcac
     3721 caaggacaag cagactgaga gcttggtaga gaaactgtgt cagcggttcc gcacagcccg
     3781 aactgagcgt cagtaccggg atctggccta ctgtgtgtcc cagctgcccc tcacagagcg
     3841 aggcctccac aaaatgctgg acaactttga ctgctttggc gataagctga tagatgagtc
     3901 tgtcttcagt gctttcttgt caattgtggg caaactgcgt cgtggggcca agcctgaggg
     3961 caaggctgta atagatgaat ttgagcagaa gcttcgtgcc tgtcacacca gaggcatgga
     4021 tggaatagag gagcttgaaa ctggccaagg aggcagccag cgggccctgt ctgccaagaa
     4081 accctccgcc ggtgtgagag tctcaaggca acagcctctg acttctgtag actcagacaa
     4141 tgactttgtc acacctaagc ctcgacgtac caaaccccgt cgtccacaaa ctcagcaacg
     4201 caagtcccag aggaaagcca aagttgtctt ctcaagtgac gagtccagtg aagatgaact
     4261 ttcagcggag atgaccgaag aagagacacc caagaaaacc acccccatcc gcagagcatc
     4321 tgcgcaaaga cacaggtcct aggagctgcc tttgcctatt cccatccctg ctgtgcaggg
     4381 tatcttactg aatgatcgag aattcaacgc cccccccccc ccttggaaaa tacttgttgc
     4441 ctccttgttt ttaacatgta aatggtcttt tcgagcaagg cctttctctt agagcccctg
     4501 actgctactt tccaagatcc aatcaccatg ttttctagtg aataaatgtt tttatatact
     4561 tttaa
//
