LOCUS       XM_006247322            4415 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus NBR1, autophagy cargo receptor (Nbr1),
            transcript variant X2, mRNA.
ACCESSION   XM_006247322
VERSION     XM_006247322.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051345.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006247322.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006247322.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4415
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4415
                     /gene="Nbr1"
                     /gene_synonym="Ca125; RGD1311421"
                     /note="NBR1, autophagy cargo receptor; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 3 mRNAs, 99 ESTs, 1 long SRA read, 7 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 227 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:303554"
                     /db_xref="RGD:69195"
     CDS             266..3217
                     /gene="Nbr1"
                     /gene_synonym="Ca125; RGD1311421"
                     /codon_start=1
                     /product="next to BRCA1 gene 1 protein isoform X1"
                     /protein_id="XP_006247384.1"
                     /db_xref="GeneID:303554"
                     /db_xref="RGD:69195"
                     /translation="MEPQVTLNVTFKNETQSFLVSDPENTTWADVEAMVKVSFDLNTI
                     QIKYLDEENEEISINSQGEYEEALKMANIKQGNQLQMQVHEGCHVVDEVLPQTVVEKQ
                     ATARTGKKPLAHYSSLVRVLGSDMKTTEEPTAEARSPVPCDTDKPQDKPPDWFTSYLE
                     MFREQVVKETVEKLEQRLQEKLVLQKPPFSSSPSEVSMPISEEETLFLPENQFSWHIA
                     CSHCQKRIVGVRYQCSLCPSYNICEDCEAGPYSHDTNHILLKFRRPVVISSEPFFYSK
                     YPTPRLPAALEQVRLQKQVDKNFVKAEKQRLRAEKKQRKAEVKELKKQLKLHRKIHLW
                     NSIHGLQSPKSPLGRPESLLQSNTLMLPLQPCAPVMPTLSAAFVDENLPDGTHLQPGT
                     KFIKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVLVPCLKAGHIGVVSVEFIA
                     PTLEGTYTSHWRLSHKGQQFGPRVWCSIIVDPFPSSESPVNLERDGISSSKADDFTCE
                     QEEAFLLAEEEIPLGEVTKQTEGTGSSAPQKTQHAASERELYIPSVDLLTAQDLLSFE
                     LLDINIVQELERVPHNTPVDVTPRMSPLPHDSPLIEKPGLGRIQEESEGAGLKASPDS
                     TVLTKRKAETPASVEETEEDLSGTQFVCETVIRSLTLDAAPDHNPPCRQRSPQRELQL
                     YSTEEQQPLMLPGFCRKDSSLKFALPEEGPHGDEREEIVHIAEEEAIEEEDVQDEEVQ
                     SQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGEPGIESGQEPAEAR
                     ERLPERESQPKEQSISDILTTSQHLDTVPLVPEVAGLPAALSRSAPCGQYEAPRVDSP
                     VTIQEVLPVPDHVRGEPRGSTGLANSRQKSCDHSRHHNGSSIAGGLVKGALSVAASAY
                     KALFSGPPVTAQPVISEDQTAALMAHLFEMGFCDRQLNLRLLRKHNHNILQVVTELLQ
                     VNNNDWYSHRY"
ORIGIN      
        1 ggaaaactcc gggaaacatg ggactaggcc cggtctctgt ccgccatgtt agattcaccc
       61 cgcagggata gcagccgagc tggccgcgaa cgattcttgc actggccact ggcaagcgcc
      121 ccccgtgggc ggaaagctgg ctgacctaga actcttggac tcctgctacc atcctgctgc
      181 aacttcctga gtaactggga ctacaggtgt gtgctcacct cagcttttct ctctgacgtg
      241 caagttctat ctccagcccg acagcatgga accacaggtt actctaaatg tgacttttaa
      301 aaatgaaact caaagctttc tggtttcgga tccagaaaat acaacttggg ctgatgttga
      361 agctatggta aaagtttcat ttgatctgaa tactatccaa ataaaatacc tggatgagga
      421 aaatgaggag atatccatca atagtcaagg agaatatgaa gaagcactta agatggctaa
      481 cattaagcaa ggaaatcaac tacagatgca agtccacgaa gggtgccatg ttgtagatga
      541 agtgctcccc caaactgtag tagaaaaaca agcaactgcc aggacaggga agaagccact
      601 cgcacattac tcttcgctgg taagagtctt gggatcagat atgaagacca cagaggagcc
      661 tacagcagag gcacgttcac ctgttccttg tgacaccgac aagcctcaag acaagccccc
      721 agactggttt acaagctacc tggagatgtt cagagaacaa gtggtgaagg aaacggtgga
      781 gaagcttgaa cagaggttgc aggagaagct tgtcctccag aagccaccct tcagttcctc
      841 accctcagaa gtctcaatgc ctatttcaga ggaggaaacc ctgtttttgc cagagaacca
      901 gttcagctgg catattgctt gtagccactg ccaaaagagg atcgtcggtg tgcgctacca
      961 gtgtagcctc tgcccatcct acaacatttg tgaagattgt gaagctggac cttactccca
     1021 tgacactaac cacattttgc taaaatttcg gagacctgtt gtgatttcct ctgagccatt
     1081 tttctactca aagtatccca ctcctcgtct gcctgctgct ttggaacaag tcaggctcca
     1141 aaagcaggtg gataagaatt ttgtgaaagc agaaaagcaa aggttgcggg ctgagaagaa
     1201 acagcggaag gcagaggtca aagagcttaa aaagcagctg aaactccacc ggaagattca
     1261 tttgtggaat tcaatccatg gactccagag tcccaagtcg cctttgggtc gacctgagag
     1321 cttgctgcag tctaacaccc tcatgcttcc tttgcagccc tgtgccccag ttatgccaac
     1381 actcagtgca gcattcgtgg atgagaattt gcctgatggg actcatcttc agccaggaac
     1441 caagtttatc aaacactgga ggatgaaaaa cacagggaat gtgaagtgga gcgcagacac
     1501 aaagctcaag ttcatgtggg gaaacttgac tctggcttct acagagaaga aggatgtttt
     1561 ggttccctgc ttgaaggctg gacacatcgg ggtggtgtct gtggagttca tcgccccaac
     1621 cttggagggg acatacactt cgcattggcg tctctctcac aaaggccagc agtttgggcc
     1681 tcgggtctgg tgcagtatca tagtggatcc ttttccttcc tctgagagcc ctgttaacct
     1741 tgaaagggat gggattagct caagcaaagc tgatgacttc acctgtgagc aagaggaagc
     1801 ttttcttcta gctgaagaag agattccatt gggtgaggtg acaaagcaga cagaagggac
     1861 aggatccagt gccccacaga agacacaaca tgctgccagt gagagggagc tctacattcc
     1921 atccgtggac cttctgactg cccaggacct gctgtccttt gaactgctgg atataaacat
     1981 tgttcaagaa ttggagagag tgccacacaa cacccctgtg gatgtgactc cccgcatgtc
     2041 tcctctgccg catgacagcc ctttaataga gaagccaggc ttggggcgga tacaggaaga
     2101 gagtgaaggg gcgggattga aagcatctcc tgattccact gtattaacaa agagaaaggc
     2161 cgagacccct gcttcagtcg aagaaacgga ggaagacctg agtgggaccc aatttgtgtg
     2221 tgagactgta atccgatccc taaccttgga tgctgctcca gaccacaacc ctccttgcag
     2281 gcagaggtcc ccacagaggg aattacagct gtattccaca gaagaacagc agcctcttat
     2341 gctgcccgga ttctgcagaa aggattcttc cttgaaattt gccttgcctg aagaaggacc
     2401 acatggagat gagagggagg agattgtcca cattgctgag gaagaagcca ttgaggaaga
     2461 ggatgtccaa gatgaagaag ttcagagtca gtcttctgct tcctctgaag attatatcat
     2521 catcctgcct gagtgctttg ataccagccg ccccctgggg gactccatgt acagctctgc
     2581 gctctcccag ccaggcctgg agcgaggggc tgaaggtgaa cctgggatcg agtctgggca
     2641 ggaaccagct gaggctagag agagactccc ggaaagggag agccagccaa aggagcagag
     2701 catcagtgac atcctcacga cctcacagca tctggacaca gtgcctctag tcccagaagt
     2761 ggcaggactt ccagcagcac tgtccaggag cgccccttgt ggacagtatg aggcaccacg
     2821 agtggattca ccagttacca tccaagaagt tctcccagtc cccgatcacg tcagaggaga
     2881 gcccagaggc tcaacaggac tcgcaaacag ccgacagaag agctgtgacc actcaaggca
     2941 ccacaatggg agcagcattg ctggaggact ggtgaaaggg gctttgtctg ttgctgcctc
     3001 tgcgtacaag gccctgtttt ctgggccacc agtcactgca cagcccgtca tttctgaaga
     3061 tcagaccgca gccctgatgg cccatctctt tgaaatggga ttctgcgaca ggcagctgaa
     3121 cctaagactg ctgagaaaac acaatcacaa tatcctgcag gttgtgacag agctcctcca
     3181 agtgaacaac aacgactggt acagccaccg ctattgagga ctggcctcgt attaaataac
     3241 tgcctgccgc tcagaggtgg tctgtgccgt catgtcattg aggtgtgggt ggaagccctt
     3301 gcttgctttt taatctgatg aatctatgtc gagcgtccct gaattgtcaa agccgtacct
     3361 gttacagtat tttttggagc aatcaaaggc cagaacttaa attttcactt tagaaatgga
     3421 tgaatggtag gaagacagtt ttcaactgat ctggacagaa ctctctctgc tgtagtatgt
     3481 ggaagcgtgt aacttggact tcctgtagac tgcttctcct tctgcttgta ttgaagttga
     3541 gtattttcct ttggtttatg tggatgtttt taatgggctg ttaaatgtta gtttggtttt
     3601 tctgtttttt aaagattaac cttgaatgtt ttcaagaatt attctaattt ctataaccaa
     3661 ccccaagctt catagctatg taaagacagc agatcaagaa agtcatgtcc ctaaaagact
     3721 tagtaaataa gtaacacttt gctttcagaa gacctggcag gaacctggaa ggatggcagg
     3781 catgctggtt aacccacagc acctactgga cagcgtctgt caaagtaact ctgcatacat
     3841 tttttaagga aaaatcctgg gtagtgtgaa atattttgct agtcctataa agagggggaa
     3901 acccacctgt tggagaaagg gaacgttaac atcatctttt tttctgtcac agcagatggt
     3961 aaggaggaca ggtgtgtgta aatattcaca tcagtaaggt tacggtgcga aggaggggac
     4021 acacatgctg gtgacgtctc gaatgtgtgt aatccccttc tgaggtgtcc agccaagagc
     4081 aagaagtagt gcttgggggc taacccacag aaaggtcagt ttaccactac agtaagtggg
     4141 aagaagcttc ctttcagagt tctaggtctc atttagttta taaaagggca ctttgggtac
     4201 agatgggtac agaggtcaca acactaaaga ttttactcct ggtaagaatt tgagagaagg
     4261 aatctggact ccagttcaaa ggggaaagat aggtgaaata gtattattta acttagttgg
     4321 tatttataat aaatggcgat tttaattatt cataatatgt ttatttacag tctaactctt
     4381 gaatgcttct aaataaacca caattcaaac tgcaa
//
