LOCUS       NM_138529              10465 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus neuron navigator 2 (Nav2), mRNA.
ACCESSION   NM_138529 XM_001080281 XM_001080288 XM_341864
VERSION     NM_138529.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 10465)
  AUTHORS   McNeill,E.M., Klockner-Bormann,M., Roesler,E.C., Talton,L.E.,
            Moechars,D. and Clagett-Dame,M.
  TITLE     Nav2 hypomorphic mutant mice are ataxic and exhibit abnormalities
            in cerebellar development
  JOURNAL   Dev Biol 353 (2), 331-343 (2011)
   PUBMED   21419114
REFERENCE   2  (bases 1 to 10465)
  AUTHORS   McNeill,E.M., Roos,K.P., Moechars,D. and Clagett-Dame,M.
  TITLE     Nav2 is necessary for cranial nerve development and blood pressure
            regulation
  JOURNAL   Neural Dev 5, 6 (2010)
   PUBMED   20184720
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 10465)
  AUTHORS   Manabe,R., Tsutsui,K., Yamada,T., Kimura,M., Nakano,I., Shimono,C.,
            Sanzen,N., Furutani,Y., Fukuda,T., Oguri,Y., Shimamoto,K.,
            Kiyozumi,D., Sato,Y., Sado,Y., Senoo,H., Yamashina,S., Fukuda,S.,
            Kawai,J., Sugiura,N., Kimata,K., Hayashizaki,Y. and Sekiguchi,K.
  TITLE     Transcriptome-based systematic identification of extracellular
            matrix proteins
  JOURNAL   Proc Natl Acad Sci U S A 105 (35), 12849-12854 (2008)
   PUBMED   18757743
REFERENCE   4  (bases 1 to 10465)
  AUTHORS   Peeters,P.J., Baker,A., Goris,I., Daneels,G., Verhasselt,P.,
            Luyten,W.H., Geysen,J.J., Kass,S.U. and Moechars,D.W.
  TITLE     Sensory deficits in mice hypomorphic for a mammalian homologue of
            unc-53
  JOURNAL   Brain Res Dev Brain Res 150 (2), 89-101 (2004)
   PUBMED   15158073
REFERENCE   5  (bases 1 to 10465)
  AUTHORS   Merrill,R.A., Plum,L.A., Kaiser,M.E. and Clagett-Dame,M.
  TITLE     A mammalian homolog of unc-53 is regulated by all-trans retinoic
            acid in neuroblastoma cells and embryos
  JOURNAL   Proc Natl Acad Sci U S A 99 (6), 3422-3427 (2002)
   PUBMED   11904404
  REMARK    GeneRIF: A mammalian homolog of unc-53 is regulated by all-trans
            retinoic acid in neuroblastoma cells and embryos
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Dec 17, 2009 this sequence version replaced
            XM_341864.3, XM_001080281.1, XM_001080288.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760386,
                              SAMEA5760393 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-258               JAXUCZ010000001.1  108094636-108094893
            259-376             JAXUCZ010000001.1  108213797-108213914
            377-429             JAXUCZ010000001.1  108224139-108224191
            430-502             JAXUCZ010000001.1  108248207-108248279
            503-770             JAXUCZ010000001.1  108257603-108257870
            771-937             JAXUCZ010000001.1  108268369-108268535
            938-2030            JAXUCZ010000001.1  108303017-108304109
            2031-2143           JAXUCZ010000001.1  108309255-108309367
            2144-2252           JAXUCZ010000001.1  108310338-108310446
            2253-2642           JAXUCZ010000001.1  108312243-108312632
            2643-2765           JAXUCZ010000001.1  108338921-108339043
            2766-2904           JAXUCZ010000001.1  108388222-108388360
            2905-3196           JAXUCZ010000001.1  108396866-108397157
            3197-3899           JAXUCZ010000001.1  108398561-108399263
            3900-4358           JAXUCZ010000001.1  108402324-108402782
            4359-4424           JAXUCZ010000001.1  108403809-108403874
            4425-4469           JAXUCZ010000001.1  108405205-108405249
            4470-4630           JAXUCZ010000001.1  108407944-108408104
            4631-4819           JAXUCZ010000001.1  108409537-108409725
            4820-4872           JAXUCZ010000001.1  108414647-108414699
            4873-4896           JAXUCZ010000001.1  108415587-108415610
            4897-4971           JAXUCZ010000001.1  108415720-108415794
            4972-5055           JAXUCZ010000001.1  108420867-108420950
            5056-5167           JAXUCZ010000001.1  108421360-108421471
            5168-5313           JAXUCZ010000001.1  108422812-108422957
            5314-5486           JAXUCZ010000001.1  108426104-108426276
            5487-5640           JAXUCZ010000001.1  108433084-108433237
            5641-5803           JAXUCZ010000001.1  108434258-108434420
            5804-5904           JAXUCZ010000001.1  108435297-108435397
            5905-6000           JAXUCZ010000001.1  108437947-108438042
            6001-6169           JAXUCZ010000001.1  108439302-108439470
            6170-6405           JAXUCZ010000001.1  108444186-108444421
            6406-6560           JAXUCZ010000001.1  108445603-108445757
            6561-6632           JAXUCZ010000001.1  108445958-108446029
            6633-6829           JAXUCZ010000001.1  108446727-108446923
            6830-6948           JAXUCZ010000001.1  108447199-108447317
            6949-7152           JAXUCZ010000001.1  108452507-108452710
            7153-10465          JAXUCZ010000001.1  108455234-108458546
FEATURES             Location/Qualifiers
     source          1..10465
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..10465
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /note="neuron navigator 2"
                     /db_xref="GeneID:171563"
                     /db_xref="RGD:619778"
     CDS             1..7278
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /EC_number="3.6.1.1"
                     /note="retinoic acid inducible in neuroblastoma cells 1"
                     /codon_start=1
                     /product="neuron navigator 2"
                     /protein_id="NP_612538.1"
                     /db_xref="GeneID:171563"
                     /db_xref="RGD:619778"
                     /translation="MPAILVASKMKSGLPKPVHSAAPILHVPPARTGPQPCYLKLGSK
                     VEVSKTAYTSQIPLKSQGLQEPTGEGLPLRKSSSLENGFDTQIYTDWANHYLAKSGHK
                     RLIKDLQQDVTDGVLLAQIIQVVANDKIEDINGCPKNRSQMIENIDACLNFLAAKGIN
                     TQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQQQPEKQHLSSSPLPPAGSQVAGAPS
                     QCQSGILQQQGLATPQAPCQPLQPASHQQAKTQAEMQSRLPGPTARVAAAGSEAKTRG
                     GSTAANNRRSQSFNNYDKSKPVPSPPQPAPPSNHEKEPLASSASSHPGMSENVPASLE
                     SSPSIPVNCSSSAIPQPSMTSKPWRSKSLSVKHSATSSMLSVKPAGPEAPRPTPEAMK
                     PAPNNQKSMLEKLKLFNSKGGSKAGEGSASRDTSCERLEILPSFEESEELEVANRAPP
                     TAGPASSSPKIALKGIAQRTFSRALTNKKSSPKGNEKEKEKQQREKEKETGKDLTKRV
                     SVTDRPDLKEEPKEELSGVVVTEMPKKSSKIASFIPKGGKLSSTKKEATAPSHSGIPK
                     PGMKNMPGKSPSAPIPPKEGERSRGKLSSGLPPQKPQLDSRHSSSSSSLASSEGKGPG
                     GTTLNHSISSQTVSGSIGTTQTTGSNTVSVQLPQPQQQYSHPNTATVAPFLYRSQTDT
                     EGNVTAESSSAGVSMEPSHYTKSGQPALEELTAEDPEARRLRTVKNIADLRQNLEETM
                     SSLRGTQVTHSTLETTFDTNVTTEISGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPS
                     MGNGYPPRANASRFISAEAGRYVYSAPLRRQLASRGSSICHVDVSDKVGDEVDLEGIS
                     MDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTS
                     LGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRRNLDVQTDAE
                     KHSQVERNSLWSGDDIKRSDGGSDSGVKMEPGSKWRRNPSDMSDESDKSVSGKKNPVL
                     SQTGSWRRGMTAEVGITMPRTKPSAQTGTLKTSGTGKTDDAKVSEKGRLSPKASQVKR
                     SPSDAGRSSGDESKKTLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGATVTSRSA
                     TLGKIPKSSALVGRSTGRKTSMDGAPNQDDGYLSLSSRTNLQYRSLPRPSKSNSRNGA
                     GNRCSTSSIDSNMSSKSAGLPVPKLREPSKTSLGSSLPGLVNQTDKEKGISSDNESVA
                     SCNSVKVNPATQPVSNSTQATLQPGTKYTDVASPTLRRLFGGKPTKQVPIATAETMKS
                     AVVISNPHATMTQQGNLESPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSGPS
                     NSLTWGTSSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGGLSHNSSPGPVASTKEDS
                     LMPFVRTSSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPT
                     SQLRTQEDTKEWFRSHSAGGLQETATNSPFSSGSSVTSPSGTRFNFSQLASPTAVTQM
                     SLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGS
                     SLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSL
                     GNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGS
                     AQATDLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKK
                     SPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNAHSNSLISECMDSEAETVM
                     QLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGS
                     GCSRAPSQVSISASPRQSLGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVV
                     SFQEAMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNS
                     DSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTILVTVKGLTENSLDSLVFESLIPK
                     PILQRYVSLLTEHRRIILSGPSGTGKTYLANRLSEYVVLREGRELTDGVIATFNVDHK
                     SSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYI
                     IGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNAEL
                     VKIINWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPY
                     LLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSL
                     PREGSTSKQVPPSDTEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLE
                     STL"
     exon            1..258
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            259..376
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            377..429
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            430..502
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            503..770
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            771..937
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            938..2030
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            2031..2143
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            2144..2252
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            2253..2642
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            2643..2765
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            2766..2904
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            2905..3196
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            3197..3899
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            3900..4358
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            4359..4424
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            4425..4469
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            4470..4630
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            4631..4819
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            4820..4872
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            4873..4896
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            4897..4971
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            4972..5055
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            5056..5167
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            5168..5313
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            5314..5486
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            5487..5640
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            5641..5803
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            5804..5904
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            5905..6000
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            6001..6169
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            6170..6405
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            6406..6560
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            6561..6632
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            6633..6829
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            6830..6948
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            6949..7152
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
     exon            7153..10465
                     /gene="Nav2"
                     /gene_synonym="Rainb1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgccggcca tcctggtagc ctccaaaatg aaatcgggac tgcccaaacc ggtgcatagc
       61 gccgcgccca tcctgcacgt ccccccggcc cggactggtc ctcaaccctg ctatcttaag
      121 ttgggaagca aggtagaggt gagcaagacg gcctacacta gccaaatccc cctgaaatcg
      181 caggggctgc aggagccgac gggggagggg ctcccgttgc ggaagagcag ctctctggag
      241 aacgggttcg atacccagat ctacacggat tgggccaatc attacctcgc taaatccggc
      301 cacaaacgcc tcatcaagga cctccagcaa gatgtgaccg acggcgtgct cctggcccag
      361 atcatccagg tcgtagcaaa tgacaagatt gaagacatca atggctgtcc aaagaacagg
      421 tcgcaaatga ttgaaaacat agatgcctgc ttgaatttcc tggcagctaa ggggatcaac
      481 acccaggggc tgtctgcaga agagatcagg aatgggaacc tcaaggccat tctaggcctc
      541 ttcttcagcc tctcccgata caagcagcaa cagcagcagc agcagcctga gaagcagcac
      601 ctctcatcat cccctctgcc acctgccggg tctcaggtgg ccggggcgcc ttcccagtgc
      661 cagtctggca ttcttcagca acaggggctg gccactcccc aagccccgtg ccagcccctc
      721 cagccagctt cacatcagca agcaaaaaca caagcggaaa tgcagtccag actcccaggt
      781 cctaccgcca gggtggccgc tgcaggcagc gaggccaaaa cacgcggagg gtcaactgct
      841 gccaacaacc gccggagtca gagctttaac aactacgaca agtccaaacc tgtcccttct
      901 ccaccccaac ccgcgccacc gagtaaccat gagaaagagc cattggccag ctcagcctcc
      961 tcccatcccg gaatgagcga aaatgtgccc gcttccttgg aaagcagccc ttccatccct
     1021 gttaactgct cctcctcagc catcccccag cccagcatga cctccaagcc ttggcgcagc
     1081 aagtccctca gtgtgaagca tagtgctacg tcatccatgc tctcagtcaa acccgctggg
     1141 cctgaggctc ccaggcccac acctgaagcc atgaagcctg cccccaacaa tcagaaatcc
     1201 atgttggaaa agctcaaact tttcaacagt aagggaggct ccaaagcggg cgagggctca
     1261 gcatcccggg acacgagctg tgagcggtta gagatcctgc ccagctttga agagagcgaa
     1321 gagttggagg tcgctaacag ggcgcctcct actgcaggcc ctgcatccag tagccccaag
     1381 attgcactca agggcattgc acagaggact ttcagcaggg cgcttaccaa taagaagagc
     1441 tccccaaagg gcaatgagaa agagaaggag aaacagcaga gggagaagga gaaggagact
     1501 ggcaaggacc tcaccaagag agtctctgtg actgacaggc ctgacctcaa ggaagaaccc
     1561 aaggaagagc tcagtggggt ggttgtgaca gagatgccca aaaagtcctc caagatcgcc
     1621 agctttatcc ccaaaggcgg gaagctcagc agcaccaaga aggaggccac agcaccatcc
     1681 cacagcggca taccaaaacc agggatgaag aacatgcctg ggaagtcccc aagtgccccc
     1741 atacctccca aggaaggaga gaggagcaga gggaagctga gctcagggct tcctccccag
     1801 aagccccagc tggacagcag gcactctagc tcctcctcca gcctggcatc ctcagagggg
     1861 aaaggcccgg gagggaccac tctgaaccac agcatcagca gccaaaccgt cagcggctcc
     1921 atcgggacca cacagaccac tggaagcaat accgtcagtg tccagctacc tcagcctcag
     1981 cagcaataca gccatcccaa cacagccacg gtcgcacctt ttctgtacag gtcccagacg
     2041 gacaccgaag ggaacgtcac tgccgagtcc agctcagcgg gtgtgagcat ggagcccagc
     2101 cactacacca agagtggaca gcctgctctg gaggaactca ctgcggaaga ccccgaggct
     2161 cggcgacttc ggacagtgaa gaacatcgca gacctaagac agaatttaga agagaccatg
     2221 tccagtttac ggggaactca ggttacacac agtacgttag aaaccacgtt tgacaccaac
     2281 gtcaccacag agataagcgg ccgcagcatc ctcagcctca cgggaagacc cactcccctg
     2341 tcctggagac ttggacagtc cagcccccgg ctccaggcag gagatgcccc ttcgatgggc
     2401 aatgggtatc cacctcgagc caatgccagc cgcttcatca gtgccgaggc aggccgctac
     2461 gtgtactctg ctcctctgag aaggcagctg gcctccaggg gcagcagcat ctgccatgtg
     2521 gatgtctcag acaaggtggg cgatgaagta gacctggaag gcatcagcat ggacgcccct
     2581 ggctacatga gtgatggcga cgtcctgagc aagaacatcc gaactgatga catcactagc
     2641 gggtatatga ccgatggcgg acttggcctt tacactcgtc gcctgaaccg gcttcctgat
     2701 gggatggctg tggtgcgaga gaccctacaa cgaaatacct ccctgggcct cggagatgct
     2761 gacagctggg atgacagcag ctccgtcagc agcggcatca gcgacaccat agacaacctc
     2821 agcacggatg acatcaacac cagctcatcc atcagctcct atgccaacac gcctgcctcc
     2881 tcccggagaa acctggatgt gcagactgac gctgagaagc actcacaggt ggagaggaat
     2941 tccctgtggt ctggtgacga catcaagaga tcagatggag gttccgacag tggtgtgaag
     3001 atggagccgg gctccaagtg gaggcggaac ccttcagaca tgtccgatga gtcggacaaa
     3061 agtgtgtctg gcaagaagaa tccagtcctc tcacagacag gctcatggcg gagaggcatg
     3121 acagcagagg tgggcatcac catgccaagg accaagccat cagctcagac aggcaccctg
     3181 aagacctcag ggactggaaa aacagacgat gccaaggtgt ctgagaaggg aaggctttcg
     3241 cctaaagctt cccaggtcaa gcgctccccg tcagatgctg gccgcagcag tggggatgaa
     3301 tccaaaaaga ccctccccag cagctctagg acgcccacag ccaatgccaa cagctttggg
     3361 ttcaagaaac agagtggctc tgctgctggg ctggccatga tcacagccag tggggccact
     3421 gtcaccagca ggtctgccac actgggtaaa atccccaagt cgtccgccct cgtcggtcgg
     3481 tccacgggtc ggaagacaag catggatgga gccccaaacc aggacgatgg gtatctgtcc
     3541 ctcagctccc ggacgaactt acagtaccgg agcctgccta ggcccagcaa gtccaacagc
     3601 cggaacggag cagggaatag gtgtagcacc agcagcatcg actctaacat gagcagcaag
     3661 tcagcaggcc tgcccgtgcc caagctgagg gagccctcca aaacatccct gggcagctcc
     3721 ctaccggggc ttgtcaacca gacggacaag gagaaaggca tctcttcaga caacgagagt
     3781 gtggcttcct gcaactctgt gaaggtgaac ccagccaccc aaccagtgtc caactcaact
     3841 caggccactc tgcagccagg gaccaagtac acagatgtgg cttctcccac actccgcaga
     3901 ctctttggtg ggaagcctac caagcaagtc cccatcgcca cagcagaaac catgaaaagc
     3961 gcagtggtca tctccaaccc tcatgccact atgacccagc aaggtaacct agagtcccca
     4021 tcaggcagtg gtgtcctgag cagtgggagc agcagtcctc tctacagtaa gaacgtggac
     4081 ctcaaccagt ctcctctagc gtccagcccc agctcagccc actcaggccc ttctaacagc
     4141 ctcacctggg gtaccagctc gtcggcagtg agcaaggatg gcttgggctt ccagtctgtt
     4201 agcagcctgc ataccagctg tgagtctatt gacatatccc tcggcagcgg agggggcttg
     4261 agtcacaact cctcccctgg tccagtcgcc tccactaagg aagactcctt gatgcctttt
     4321 gtccgcacca gcagtgtgaa gaccacactg tcagaaagcc ctctctcttc ccctgctgct
     4381 agccctaagt tctgcagaag tactctgccc aggaaacagg acagtgaccc gcaccttgat
     4441 aggaacactt tgcctaagaa aggactcagg tatacaccca cctcccagct tcgcacgcag
     4501 gaagacacca aagaatggtt ccggtcccac tcagcgggag gcctgcagga gactgctacc
     4561 aactccccct tttcctctgg ctctagtgtc acttctcctt ctggaacaag attcaacttc
     4621 tctcagcttg cgagtcccac cgccgtcacc cagatgagct tgtccaaccc gacgatgctg
     4681 aggacccaca gcctgtccaa cgcggatggc cagtatgacc cctacaccga cagccgcttc
     4741 cgcaacagct ccatgtctct ggacgagaag agccgaacga tgagtcgatc gggctccttc
     4801 cgggatgggt ttgaggaagt tcatggatcc tccctgtcct tggtttccag cacatcctcc
     4861 atctactcta cgccagaaga aaaatgccag tcagagattc gaaagctgcg gcgagagctg
     4921 gatgcctccc aggaaaaggt gtctgcgctg accacccagc tgactgcaaa tgctcacctt
     4981 gtggcagcct ttgagcagag tctgggaaac atgaccatca ggctgcagag tttaactatg
     5041 actgccgagc agaaggattc agaactgaat gagttaagaa aaaccatcga gctgctaaag
     5101 aaacagaatg cagctgccca ggctgccatt aatggagtaa ttaacacgcc agagctcaac
     5161 tgcaaaggaa atggcagtgc ccaggctaca gacctacgca tccgcaggca gcactcctcc
     5221 gacagtgtct ccagtatcaa tagtgccacc agccactcga gtgttggcag taacatagag
     5281 agtgactcga agaaaaagaa gaggaaaaac tggttacgca gctccttcaa gcaagctttt
     5341 ggaaagaaga aatcccccaa gtcagcatcc tctcactcag acatcgagga gatgacggat
     5401 tcttcgttgc cctcctcacc aaaactgcca cacaatggat ccacaggctc taccccgctg
     5461 ctgaggaacg cccactcaaa ctccctcatt tccgagtgta tggacagcga agccgagacg
     5521 gtcatgcagc tacgaaatga gctgagagac aaggagatga agctgacaga catccgcctg
     5581 gaagcgctca gctccgctca ccagttagac cagctccgag aggccatgaa caggatgcag
     5641 agtgaaatcg agaagctgaa agccgagaat gaccgactga agtccgagtc ccaaggcagt
     5701 ggctgtagcc gggccccctc ccaggtgtcc atctctgctt ccccaaggca gtctttaggg
     5761 ctctcacagc atagcctgaa cctcacagag tctacgagtc tagacatgtt gctggatgac
     5821 actggtgaat gctcggctcg gaaggaagga ggcaggcatg ttaagatagt tgtcagcttt
     5881 caggaggcaa tgaagtggaa ggaggactcc agaccgcacc tcttcctcat tggctgcatt
     5941 ggagttagtg gcaaaacaaa gtgggacgtg ctcgatgggg tggttagacg gctgttcaaa
     6001 gaatacatca ttcatgtgga tccagtgagt cagctggggc tgaattcaga cagtgttctc
     6061 ggctacagca ttggtgagat caagcgcagc aacacctcgg agacccccga gctcctcccc
     6121 tgtggctatc tcgtgggaga gaacaccacc atcttggtga ccgtcaaagg gctcacggaa
     6181 aatagcctag actctctggt gttcgagtcc ctgatcccca agcccatcct gcagcgctac
     6241 gtatccctgc tgacagagca ccggcggatc atcctctcgg gccccagcgg cactggcaaa
     6301 acctacctgg ccaaccggct ctccgagtac gtggtactcc gggaaggacg ggagttgaca
     6361 gatggcgtca ttgcgacctt taatgtggat cacaagtcca gcaaggaact gcgccagtat
     6421 ctgtccaacc tggctgacca gtgcaacagc gagaacaatg ccgtggatat gcctctagtc
     6481 atcatcctgg acaacctgca ccatgtgagc tccctgggcg agatcttcaa cggactgctt
     6541 aactgcaaat accataaatg cccttacatc atcggcacga tgaaccaggc tacctcttcc
     6601 acccctaacc tgcagcttca tcataacttc aggtgggtgc tttgcgccaa ccacacggag
     6661 cccgtgaagg gtttcctagg ccgcttcctg aggaggaagc tcatggaaac ggagatcagt
     6721 gggcgggtgc gcaatgcaga gctggtgaaa atcatcaact ggatcccgaa ggtctggcat
     6781 cacctcaacc gcttcctgga ggcccacagc tcgtcggatg tcaccatcgg tccccgtctc
     6841 ttcctgtcgt gtcccattga cgtggatggt tccagagtgt ggttcaccga cctgtggaac
     6901 tactccataa tcccctacct cctggaagca gtcagagaag gactccagct ctacggaagg
     6961 cgtgccccct gggaggaccc ggccaagtgg gtaatggaca cctacccctg ggctgccagc
     7021 ccacagcagc acgagtggcc cccgctcctg cagctccggc ctgaggacgt gggcttcgat
     7081 ggctactccc tgcctaggga ggggtcgaca agcaagcagg tgccccccag cgacaccgaa
     7141 ggagacccac tgatgaacat gttgatgagg ttacaggagg cggccaacta ctccagcccc
     7201 cagagctacg acagcgactc gaacagcaac agccaccacg acgacatcct ggactcatcc
     7261 ctagagtcta ccctgtgacc gaggcccctg cttttcctct cttcatccca cccggcatcc
     7321 tccacttcat tctgaagatg acttcctgag ccagccctgg ctgccacagc cttgaagcca
     7381 gagcagagta gcaggagacc cttgtccctt gcgctctgcc cttgcatgag cagcccagga
     7441 cctcttcctc caacagtgac aactgtccta gcctctgttc taccctcatt ctcgttttct
     7501 gccttgttgc cgtgacctcc acgagacact gaaaatactt catgggaaag gatcctcacc
     7561 gctgaaatat aaagagttta aatggatatt ttaaatgtaa gattccactt ggtgccctga
     7621 aacccaacag catccctcca cacgctaccc accccagaca gaaaagacta aacccaacac
     7681 agacagtagg gcttccccca gtacagaccc accagcttgg gtctggccac cagcacccca
     7741 gagccatgcc acccaccctc cacggaagaa ttggtgctaa tgagggcgcc tgcttggagc
     7801 gccacccagg gacaccagta gatcacgtgt ctcagttttc cacatggtgc tctccttccc
     7861 gagaggtatt ctgtctattc ccgtgtgccc tttcccctgt ttccggtccg tcagcccaga
     7921 tgatctgtga gagcgagtga agacgcgaga atgtgagtga gcggatgggg ctagcaacac
     7981 ggtaaagtgc gcccgtttcc tttgtttgtc caaacggtcg ggtttctgtc cgcaaacact
     8041 gtgtactgtg tgagtagttc tttggagaac tttcgacccc tgcctatgtc tgcctttctt
     8101 cctggttgat tgtgaaggcc cctttccctc cccaacccct gaaccctact cctttgacca
     8161 gaattagtcc tttggtgaaa tcaagagcta aatagaattt gcctcctccc tcaacctggg
     8221 atttccagtg tccgttatca cagttttggg gccctcgaca ccaccttctg gagctctgtg
     8281 ggcatttgta tccttgcaga tagatgagga ccagttctcc tgtgggtgag ccacggacct
     8341 cgcctttcct tctcgtctct gagatctgag aaccccacat catcacctca ggcaccccag
     8401 accccagttg caggaggagt tgacgatgcc ccctcaccaa acactggcat tttcctcaga
     8461 accaacggga cacagcttag ccagggaggg gcggccaccc ttcccagaat cctggccgtg
     8521 cctccgtcct gatgagcctt gcctgacctc ttcggtgctg accgccccca tgcaatgcct
     8581 tactggtttc gtactgaccg tgtccattca catgagtgtt gtgcctgcct ggggttgtgt
     8641 gtgtgtgtgt gtctccccca tcgaagtaaa cagggctata agtcatctat ccatgaagag
     8701 aatacaagtt gctgacttct catccaaaag agtcatctgt gtggacgtat gattgagaga
     8761 gagagaaaga gagagagaga gagagagaga gagagagaga gagatctatg ttttttaggc
     8821 tcctatcagt ctccagtcaa ctcactagac agtgacccca caaatccatg tgaccttgta
     8881 aacccatgct ctaggagaca taccccagtg tgccatgact tcagcacact agtgttctcc
     8941 tcaccgtatg gacatctttg ggctctttgt gttttataga gactttcctg gccccaccaa
     9001 gggtgtctct gttaacaatc agggttttta tcccatcttt tgctattcta ttcttgaatg
     9061 tttgtctctc cagtttttgt tttgttttgt tttttgtttt ttttttttct taccctaaga
     9121 gtttgaccca gaactgctca ctttgcttgg aatggcactg gttttcttcc tcgttgaaag
     9181 gaaggagaac gtgtcctgtt aactggtgaa tggaaacatt tccactccct gctgtaatcc
     9241 cagatccagc ctgccttggc tactagtatg gatgcgagtg tgtcttctac tgttttgttt
     9301 gtaataaaag tttaaaacca tatgtctagc ctgtgaccag ggccaaaccc tgatccttcc
     9361 agtgcccctg aagggtcgcc cttctcagtc tatctcccag caacggccgt acactctcat
     9421 actgtgaatt tgggaggtgg gaaaatcaag cccgtcccca tgcatagttt tctcagtcac
     9481 cttaggaata caccccacca acattgctta gaactgtttc tttaacgaca ccctctgtct
     9541 gctctccaca cccagacttc tctctcccac cacatccagg atcgaaactg caacgcgtgt
     9601 acccattgct gcctgacttg gttttgtagt ccctgagcgc ctcccagctc agccaccttc
     9661 ctgaagcact gggagggggg ctgtctgaaa ggcacgtttc tgaccgggtc atgatttttc
     9721 ctttcctgtt gctcgacctt gaacaaagtg actttgtact cacttagagc tctgtctgaa
     9781 atgcttcctt ttttttctgt agataggctc attttgaaat gtaagaaatc ctatgcaact
     9841 gccgatggtg ggagccaaaa gttttcttcc caggaggccc agaattccac agacttcctt
     9901 ttaacttaag gtttggggtg ggagggtggg agtgtgacaa gggcattact tggccctgat
     9961 cttcctccga ccttgaggac attttaaatt ttattgttta atgctcggct ttaaagttgt
    10021 gtgcccagat ctgaccgtgg caaacctgct ttcagaaagc aaaaaacgat ccagcctcgt
    10081 ggatacggaa tggggggttt gctgttttga cccgcttgtc tcgagccgag cggttcatga
    10141 aacgtgttct ataagatgta catttttttt tcctcattgt aacatagaga ctgtaaataa
    10201 ccggcgaaac tgctgcattt tgatgacttt tttctagcca tttttaaaga gaaaactagg
    10261 aattgagtat tttgtgtacg gtatgtttcc accgctcccc tgccccccac ccctccctct
    10321 ccctatttaa ttctcatgtg tcatcaggtt tttgggtttg agaacaatct gctggagatc
    10381 tgccccgtgt catagagaat aaatctgacg attgtaccag tcttaaatta ttcatgattc
    10441 aataaactta atgcttattt attca
//
