LOCUS       NM_001173449            1985 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus N-acetyltransferase 8 (GCN5-related) family
            member 2 (Nat8f2), mRNA.
ACCESSION   NM_001173449 XM_001074225 XM_575587
VERSION     NM_001173449.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1985)
  AUTHORS   Ding,Y., Ko,M.H., Pehar,M., Kotch,F., Peters,N.R., Luo,Y.,
            Salamat,S.M. and Puglielli,L.
  TITLE     Biochemical inhibition of the acetyltransferases ATase1 and ATase2
            reduces beta-secretase (BACE1) levels and Abeta generation
  JOURNAL   J Biol Chem 287 (11), 8424-8433 (2012)
   PUBMED   22267734
  REMARK    GeneRIF: Biochemical inhibition of the acetyltransferases ATase1
            and ATase2 reduces beta-secretase (BACE1) levels and Abeta
            generation.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Oct 14, 2022 this sequence version replaced NM_001173449.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643286.14105.1,
                                           SRR26643286.14104.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-120               JAXUCZ010000004.1  119879639-119879758 c
            121-1985            JAXUCZ010000004.1  119877449-119879313 c
FEATURES             Location/Qualifiers
     source          1..1985
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..1985
                     /gene="Nat8f2"
                     /gene_synonym="RGD1561619"
                     /note="N-acetyltransferase 8 (GCN5-related) family member
                     2"
                     /db_xref="GeneID:500237"
                     /db_xref="RGD:1561619"
     exon            1..120
                     /gene="Nat8f2"
                     /gene_synonym="RGD1561619"
                     /inference="alignment:Splign:2.1.0"
     exon            121..1985
                     /gene="Nat8f2"
                     /gene_synonym="RGD1561619"
                     /inference="alignment:Splign:2.1.0"
     CDS             194..874
                     /gene="Nat8f2"
                     /gene_synonym="RGD1561619"
                     /note="camello-like protein 2; N-acetyltransferase-like
                     protein CML2; camello-like 2; probable N-acetyltransferase
                     CML2; probable N-acetyltransferase CML2-like"
                     /codon_start=1
                     /product="N-acetyltransferase family 8 member 2"
                     /protein_id="NP_001166920.1"
                     /db_xref="GeneID:500237"
                     /db_xref="RGD:1561619"
                     /translation="MAPYHIRQFQDRDHRRVLDLFSRGMEEHVPAAFYHVLTLPHSLL
                     LFPGVPVTIILVSGSWLLATVYSFLFLLCLRLIFWVSCRNYVAKCLQADLADITKSYL
                     NAHGSFWVAESGGQVVGIVAALPVKEPPSGRKQLQLFRLSVSSQHRGQGIAKALVRIV
                     LQFARDQGYTDVVLVTGNMQYSAMSLYQGMGFQKTGHYFVSIAKRLIGLSIFHFTYSL
                     PSVWEPRM"
ORIGIN      
        1 aggaattgtt caagctcgta cctggaaaca caggcgtttt caatgtctgg acccttaaga
       61 ggaaacagaa gatctcagaa ctgcacatct ttccacagtg tggcacctca ggtcccaaag
      121 ggctcaggaa gctgtgcaag aaggtctgga cgtccctggt gatcactgat acttgagagg
      181 cagaagtctc ctcatggctc cttatcacat cagacagttc caggacaggg accacagaag
      241 agtcctggac ttgttctcca gaggcatgga ggagcatgtc cctgctgcct tctaccatgt
      301 gctgacactg cctcattctc tcctgctctt tcctggggtg cccgtgacca taatcctagt
      361 gtctggttct tggctcctgg ccacagtgta cagtttcctc tttctccttt gcctgcggct
      421 cattttctgg gtttcatgca gaaattatgt ggctaaatgt ttgcaggccg acttggctga
      481 catcaccaag tcttacctga atgcacatgg ctccttctgg gtggctgagt ctggggggca
      541 ggtggtgggc atagtggctg ctctgccagt caaggagcct ccatcaggga ggaagcagtt
      601 gcagctcttc cgcctgtctg tgtcctcaca gcatcgagga caggggatag cgaaagcact
      661 ggtcagaatt gtgctccagt ttgcacggga ccagggctac acggatgttg tccttgtgac
      721 tggcaatatg cagtatagcg ctatgtctct gtaccagggc atgggcttcc agaagacagg
      781 ccattacttc gtcagcatag ccaagaggtt aattggtctt tctatctttc atttcaccta
      841 ctctctccct tctgtttggg aaccaagaat gtgatctttt ttcctttgtc tgcagggctc
      901 cagttcactc tgctttagga acaagccaac cctggcagtt catttaccaa gaccaaggct
      961 ccctttcgat ccctttcaga tgcagcagaa ctggtggtga cctctgggtg ttggcctcct
     1021 gctccatgct gcctttttaa gggtctctgt ttcatctttc tagtgctggg ataagagagc
     1081 acgaaaccca gccgagtgga ccctgcacac attcactagg agtctgttag ctatccgcaa
     1141 ccttggtgag ctgaagttcc agctcagaca ggattcagga tctttgcaga caagataagt
     1201 gaactcaaaa caaaggcttt cctcacacac actgaacgtg tggactattg aaaattctaa
     1261 gactcgtgta gaaatggagt cttcacagta gaggtgcacc acagtcatag gtcagggcgg
     1321 gcgccccgcg agagctagag caaggaagtg tgtaacttac tcctaagtca cccttgtgca
     1381 gaggcaggaa agggacctct gatgcagtgg gaatagcttt gaacagcctc tcctgggtgc
     1441 ttatttggtc ccagtctcat gggaaagccc aactatatgg ttacagagca tgaaaccttc
     1501 ttggggatcc aggaagatga tatggggtca ggaattctca tgaatattgc cctggagaaa
     1561 aaccccagga ccaattggca cttgcttggg tgggagagca gtaggcatcc agtgctcctg
     1621 gttatcctct gtaaaaagtt aaaatggccg ttcaggagtt agaacagcac tgtagagtgg
     1681 agaaaagtct cagaactaat gagggggttg ggtggataat atgatcttgt gtgtagtctc
     1741 ctgtatctgt ttggtctgaa ctgaagcatc ttcgtgttga gggatgactg aggatcagca
     1801 gacccagggg agggtccctc tctaaagtca cccaggcaga gagaagtctc ttaggaaccc
     1861 cagtgttgta gattgtgtga gacattacct ctgcaatggt aatactgcct gcacgaccca
     1921 tgcccccatc agtaatccct catctgagtc cctgtagctc caataaaatg tttcatccac
     1981 cttga
//
