LOCUS       NM_021668               2180 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus N-acetyltransferase 8 (GCN5-related) family
            member 1 (Nat8f1), mRNA.
ACCESSION   NM_021668
VERSION     NM_021668.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2180)
  AUTHORS   Ding,Y., Ko,M.H., Pehar,M., Kotch,F., Peters,N.R., Luo,Y.,
            Salamat,S.M. and Puglielli,L.
  TITLE     Biochemical inhibition of the acetyltransferases ATase1 and ATase2
            reduces beta-secretase (BACE1) levels and Abeta generation
  JOURNAL   J Biol Chem 287 (11), 8424-8433 (2012)
   PUBMED   22267734
  REMARK    GeneRIF: Biochemical inhibition of the acetyltransferases ATase1
            and ATase2 reduces beta-secretase (BACE1) levels and Abeta
            generation.
REFERENCE   2  (bases 1 to 2180)
  AUTHORS   Shultz,M.A., Zhang,L., Gu,Y.Z., Baker,G.L., Fannuchi,M.V.,
            Padua,A.M., Gurske,W.A., Morin,D., Penn,S.G., Jovanovich,S.B.,
            Plopper,C.G. and Buckpitt,A.R.
  TITLE     Gene expression analysis in response to lung toxicants: I.
            Sequencing and microarray development
  JOURNAL   Am J Respir Cell Mol Biol 30 (3), 296-310 (2004)
   PUBMED   12947022
REFERENCE   3  (bases 1 to 2180)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   4  (bases 1 to 2180)
  AUTHORS   Popsueva,A.E., Luchinskaya,N.N., Ludwig,A.V., Zinovjeva,O.Y.,
            Poteryaev,D.A., Feigelman,M.M., Ponomarev,M.B., Berekelya,L. and
            Belyavsky,A.V.
  TITLE     Overexpression of camello, a member of a novel protein family,
            reduces blastomere adhesion and inhibits gastrulation in Xenopus
            laevis
  JOURNAL   Dev Biol 234 (2), 483-496 (2001)
   PUBMED   11397015
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF114103.1 and BC078836.1.
            
            On Apr 25, 2009 this sequence version replaced NM_021668.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF185569.1, CK480367.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132291, SAMD00132297
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-19                CF114103.1         22-40
            20-2180             BC078836.1         1-2161
FEATURES             Location/Qualifiers
     source          1..2180
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..2180
                     /gene="Nat8f1"
                     /gene_synonym="Cml2"
                     /note="N-acetyltransferase 8 (GCN5-related) family member
                     1"
                     /db_xref="GeneID:59300"
                     /db_xref="RGD:621606"
     exon            1..109
                     /gene="Nat8f1"
                     /gene_synonym="Cml2"
                     /inference="alignment:Splign:2.1.0"
     exon            110..2152
                     /gene="Nat8f1"
                     /gene_synonym="Cml2"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..837
                     /gene="Nat8f1"
                     /gene_synonym="Cml2"
                     /note="camello-like protein 1; camello-like protein 2;
                     putative N-acetyltransferase Camello 2; camello-like 1;
                     probable N-acetyltransferase CML1-like"
                     /codon_start=1
                     /product="probable N-acetyltransferase CML1"
                     /protein_id="NP_067700.2"
                     /db_xref="GeneID:59300"
                     /db_xref="RGD:621606"
                     /translation="MPRFETQKSPMAPYHIRQYQDSDHKSVVDVFTKGMEEHIPSTFR
                     HMLMLPRTLLLLLGVPLALVLVSGSWLLAVVCIFFLLLLLRFLAGQPWKEYVATCLRT
                     DMADITKSYLNAHGSFWVAESGNQVVGIVAALPVKDPPSGRKQLQLFRLSVSSQHRGQ
                     GIAKALVRTVLQFARDQGYTDVVLETSTLQQGAMTLYLGMGFQKTGQRFLTMFWRLVG
                     IRTIQLKYPFPSA"
ORIGIN      
        1 aactactatt aatgctaggc gcttgtggcg gaggctgagg atagctactt ctgctttgtc
       61 ccggcttcgg aagcagaaag caccctacag gttgggccta gtagttgagg gttcagggat
      121 aggtatagct gtctctcctg gatgccaaga tttgagaccc agaagtctcc catggctcct
      181 tatcacatcc gccagtacca agacagcgac cacaaaagtg tcgtggatgt gttcaccaag
      241 ggcatggaag aacacatccc ctccaccttc cgccacatgc ttatgctgcc ccgaaccctc
      301 ctactcttac ttggggtgcc ccttgccctg gtcctggtgt ctggctcctg gctgctggct
      361 gttgtatgca tcttctttct gctcctactc ctgcggttcc ttgctggaca gccctggaag
      421 gagtatgtgg ctacatgttt gcggacagac atggctgaca tcaccaagtc ttacctgaat
      481 gcacatggct ccttctgggt ggctgagtct ggaaaccagg tggtgggcat agtggctgct
      541 ctgccagtca aggatcctcc atcagggagg aagcagctgc agctctttcg cctgtctgtg
      601 tcctcacagc atcgaggaca ggggatagcg aaagcactgg tcagaactgt cctccagttt
      661 gcacgggacc agggctacac tgatgttgtc cttgagacca gtaccttgca acaaggtgct
      721 atgaccctct acctgggcat gggcttccag aagacaggcc aacgcttcct gactatgttc
      781 tggaggttag tgggtattcg gacaattcaa ttaaagtatc ccttcccttc tgcctaggaa
      841 agggggctgt gaccttgagt tcctgtggag caagcatgct tctctaaact ctgctacagg
      901 aaccagtgaa ccctgtcatg tcagtgtgat taacaataaa agcttgttgc tgcacaccag
      961 cttctaatgc atgtgatggc tgacaggggg tgtgggggct ctgctgcatt cgaggtgtct
     1021 ggggtgcctg tgtttcatat acctagcccg atattactgt tgtattagaa accgtgcaaa
     1081 atactaatgt atgtatttca cttttgagtg tggaccagaa gtttctgtaa ggctggagtt
     1141 cacctaccgc caggacacct agttggttga atgtaaacat gggaagtgaa catgaaggtt
     1201 tctctctctc tctctgttcc tacatttcag gaagccatga gctttggcct ctggtcattg
     1261 tccttctcag actcagtgaa tgacaccttt gttttaattc tttgccaggt tcacacatgg
     1321 atacactgag tttcttattc tactgtcttc actcacacag gcatcactac agccgagccc
     1381 agcccacaaa caagccagga gctccccagg actggatact gatgcaagta tcagaagggt
     1441 gtttggggaa aagatcagca tcccagggtc ttgaggtgtt ttagctcatg tttacatcct
     1501 cagagtagag attttcatta gaaagatgtg cagagttata caaaatacta agaaagctca
     1561 tttaccccca ggcttcaata aaagtacatt tctaactatc gcctgtgttt agaacccaag
     1621 aaccctgtta tcctggtaga gaagatctct gactcctcag aagtagaata tgggtgtgca
     1681 tatagtcact atagtctcct tatttggaag ttagaaaaaa agtgccttta tcactttctc
     1741 ttacagcagc gcactctgca gtaaacttgc tatgtagcta tttcctaaga aatgaaacgc
     1801 tacccctttc attttatttc ctaggaaata gctactttct gaaagctcat gagacttgta
     1861 agtaagacag gttcaagagg tgagacaact taacaagatc aggaagcacc tgaaacttaa
     1921 aggattcact gaggcccacc ccaaggttct attagcagct actgctggag agaagagact
     1981 taccttcaga gctgcttgga agtggtgcag ggctccagaa tgaatggatg ttttgtaagt
     2041 catgcctgtg cctttccagt gatgaagctg cctttgagtc atccatgctc ctgtaagtaa
     2101 ctccttgttc tcattcttat acacagctca ataaactcac taattcaact aaaaaaaaaa
     2161 aaaaaaaaaa aaaaaaaaaa
//
