LOCUS       NM_022635                779 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus N-acetyltransferase 8 (Nat8), mRNA.
ACCESSION   NM_022635
VERSION     NM_022635.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 779)
  AUTHORS   Mak,A.B., Pehar,M., Nixon,A.M., Williams,R.A., Uetrecht,A.C.,
            Puglielli,L. and Moffat,J.
  TITLE     Post-translational regulation of CD133 by ATase1/ATase2-mediated
            lysine acetylation
  JOURNAL   J Mol Biol 426 (11), 2175-2182 (2014)
   PUBMED   24556617
REFERENCE   2  (bases 1 to 779)
  AUTHORS   Veiga-da-Cunha,M., Tyteca,D., Stroobant,V., Courtoy,P.J.,
            Opperdoes,F.R. and Van Schaftingen,E.
  TITLE     Molecular identification of NAT8 as the enzyme that acetylates
            cysteine S-conjugates to mercapturic acids
  JOURNAL   J Biol Chem 285 (24), 18888-18898 (2010)
   PUBMED   20392701
REFERENCE   3  (bases 1 to 779)
  AUTHORS   Ko,M.H. and Puglielli,L.
  TITLE     Two endoplasmic reticulum (ER)/ER Golgi intermediate
            compartment-based lysine acetyltransferases post-translationally
            regulate BACE1 levels
  JOURNAL   J Biol Chem 284 (4), 2482-2492 (2009)
   PUBMED   19011241
REFERENCE   4  (bases 1 to 779)
  AUTHORS   Popsueva,A.E., Luchinskaya,N.N., Ludwig,A.V., Zinovjeva,O.Y.,
            Poteryaev,D.A., Feigelman,M.M., Ponomarev,M.B., Berekelya,L. and
            Belyavsky,A.V.
  TITLE     Overexpression of camello, a member of a novel protein family,
            reduces blastomere adhesion and inhibits gastrulation in Xenopus
            laevis
  JOURNAL   Dev Biol 234 (2), 483-496 (2001)
   PUBMED   11397015
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF185570.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AF185570.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..779
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..779
                     /gene="Nat8"
                     /gene_synonym="CCNAT; Cml4"
                     /note="N-acetyltransferase 8"
                     /db_xref="GeneID:64570"
                     /db_xref="RGD:621609"
     exon            1..779
                     /gene="Nat8"
                     /gene_synonym="CCNAT; Cml4"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..684
                     /gene="Nat8"
                     /gene_synonym="CCNAT; Cml4"
                     /EC_number="2.3.1.80"
                     /note="probable N-acetyltransferase CML4; camello-like
                     protein 4; putative N-acetyltransferase Camello 4;
                     camello-like 4; N-acetyltransferase 8 (camello like);
                     ATase2; acetyltransferase 2; cysteinyl-conjugate
                     N-acetyltransferase"
                     /codon_start=1
                     /product="N-acetyltransferase 8"
                     /protein_id="NP_072157.1"
                     /db_xref="GeneID:64570"
                     /db_xref="RGD:621609"
                     /translation="MASFHIRQFQERDYEQVVDMFSRGMKEHIPTAFRHLLLLPRTLL
                     LLLGVPLALVLVSGSWLLAVVCIFFLLPFLWFLAGQPWKNYVSKCLHTDMADITKSYL
                     SDRGSGFWVAESGGQIVGTVGALPVKDPPSGRKQLQLFRLSVSSQHRGQGIAKALVRT
                     VLQFARDQGYTDVVLVTGLLQQGAVTLYYSMGFQKTGESFMDILTWLVDVSLIHFIYP
                     LPSS"
ORIGIN      
        1 agacgaaggt ttcccatggc ttcttttcac atccgccagt tccaggagag ggactatgaa
       61 caggtcgtgg atatgttctc caggggaatg aaggaacaca tccccactgc cttccgccac
      121 ttgctgctgc tgccccgaac cctcctactc ttacttgggg tgccccttgc cctggtcctg
      181 gtgtctggct cctggctgct ggctgttgta tgcatcttct ttctgctccc atttttgtgg
      241 ttccttgctg gacagccctg gaagaattat gtgtccaaat gcttacacac agacatggct
      301 gacatcacca agtcttatct gagtgatcgt ggctcaggtt tctgggtggc tgagtctggg
      361 ggccagatag tgggcacagt gggtgctctg ccagtcaagg atcctccatc agggaggaag
      421 cagttgcagc tcttccgcct gtctgtgtcc tcacagcatc gaggacaggg gatagcgaaa
      481 gcactggtca gaactgtgct ccagtttgca cgggaccagg gctacacgga tgttgtcctt
      541 gtgactggcc ttttgcagca aggtgctgtg accctctact acagcatggg cttccagaag
      601 acaggcgaat ccttcatgga catactcaca tggcttgtgg atgtttctct aattcatttc
      661 atatacccgc tcccttcctc ctgagaacct gagtttcgat ccctctgtgt gtctgtcagc
      721 ctctggttca ctgtgctgtg ggaacaaata atcctgatat tgtagtggac aaatcaccc
//
