LOCUS       NM_001191966            4673 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus NSF attachment protein beta (Napb), mRNA.
ACCESSION   NM_001191966 XM_575249
VERSION     NM_001191966.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4673)
  AUTHORS   Burgalossi,A., Jung,S., Meyer,G., Jockusch,W.J., Jahn,O.,
            Taschenberger,H., O'Connor,V.M., Nishiki,T., Takahashi,M., Brose,N.
            and Rhee,J.S.
  TITLE     SNARE protein recycling by alphaSNAP and betaSNAP supports synaptic
            vesicle priming
  JOURNAL   Neuron 68 (3), 473-487 (2010)
   PUBMED   21040848
  REMARK    Erratum:[Neuron. 2012 Feb 9;73(3):620]
REFERENCE   2  (bases 1 to 4673)
  AUTHORS   Werner,H.B., Kuhlmann,K., Shen,S., Uecker,M., Schardt,A.,
            Dimova,K., Orfaniotou,F., Dhaunchak,A., Brinkmann,B.G., Mobius,W.,
            Guarente,L., Casaccia-Bonnefil,P., Jahn,O. and Nave,K.A.
  TITLE     Proteolipid protein is required for transport of sirtuin 2 into CNS
            myelin
  JOURNAL   J Neurosci 27 (29), 7717-7730 (2007)
   PUBMED   17634366
REFERENCE   3  (bases 1 to 4673)
  AUTHORS   Martin,H.G., Henley,J.M. and Meyer,G.
  TITLE     Novel putative targets of N-ethylmaleimide sensitive fusion protein
            (NSF) and alpha/beta soluble NSF attachment proteins (SNAPs)
            include the Pak-binding nucleotide exchange factor betaPIX
  JOURNAL   J Cell Biochem 99 (4), 1203-1215 (2006)
   PUBMED   16795052
  REMARK    GeneRIF: A yeast two-hybrid screen using NSF as bait identified
            Rab11-FIP3 and the Pak-binding nucleotide exchange factor betaPIX
            as putative binding partners
REFERENCE   4  (bases 1 to 4673)
  AUTHORS   Hong,H.K., Chakravarti,A. and Takahashi,J.S.
  TITLE     The gene for soluble N-ethylmaleimide sensitive factor attachment
            protein alpha is mutated in hydrocephaly with hop gait (hyh) mice
  JOURNAL   Proc Natl Acad Sci U S A 101 (6), 1748-1753 (2004)
   PUBMED   14755058
REFERENCE   5  (bases 1 to 4673)
  AUTHORS   Hanley,J.G., Khatri,L., Hanson,P.I. and Ziff,E.B.
  TITLE     NSF ATPase and alpha-/beta-SNAPs disassemble the AMPA
            receptor-PICK1 complex
  JOURNAL   Neuron 34 (1), 53-67 (2002)
   PUBMED   11931741
REFERENCE   6  (bases 1 to 4673)
  AUTHORS   Yoo,B.C., Cairns,N., Fountoulakis,M. and Lubec,G.
  TITLE     Synaptosomal proteins, beta-soluble N-ethylmaleimide-sensitive
            factor attachment protein (beta-SNAP), gamma-SNAP and synaptotagmin
            I in brain of patients with Down syndrome and Alzheimer's disease
  JOURNAL   Dement Geriatr Cogn Disord 12 (3), 219-225 (2001)
   PUBMED   11244216
REFERENCE   7  (bases 1 to 4673)
  AUTHORS   Nishiki,T., Nihonmatsu,I., Tsuhara,Y., Kawasaki,M., Sekiguchi,M.,
            Sato,K., Mizoguchi,A. and Takahashi,M.
  TITLE     Distribution of soluble N-ethylmaleimide fusion protein attachment
            proteins (SNAPs) in the rat nervous system
  JOURNAL   Neuroscience 107 (3), 363-371 (2001)
   PUBMED   11718992
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Oct 25, 2022 this sequence version replaced NM_001191966.1.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.677478.1,
                                           SRR26360194.999693.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760393,
                                           SAMN12840106 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-153               JAXUCZ010000003.1  156632266-156632418 c
            154-233             JAXUCZ010000003.1  156604707-156604786 c
            234-350             JAXUCZ010000003.1  156600558-156600674 c
            351-397             JAXUCZ010000003.1  156598403-156598449 c
            398-475             JAXUCZ010000003.1  156598192-156598269 c
            476-531             JAXUCZ010000003.1  156594468-156594523 c
            532-616             JAXUCZ010000003.1  156594270-156594354 c
            617-721             JAXUCZ010000003.1  156592776-156592880 c
            722-790             JAXUCZ010000003.1  156591268-156591336 c
            791-841             JAXUCZ010000003.1  156590520-156590570 c
            842-4673            JAXUCZ010000003.1  156585394-156589225 c
FEATURES             Location/Qualifiers
     source          1..4673
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..4673
                     /gene="Napb"
                     /gene_synonym="SNAP-beta; Snapb"
                     /note="NSF attachment protein beta"
                     /db_xref="GeneID:499903"
                     /db_xref="RGD:1589649"
     exon            1..153
                     /gene="Napb"
                     /gene_synonym="SNAP-beta; Snapb"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..952
                     /gene="Napb"
                     /gene_synonym="SNAP-beta; Snapb"
                     /note="N-ethylmaleimide sensitive fusion protein
                     attachment protein beta; N-ethylmaleimide-sensitive factor
                     attachment protein beta"
                     /codon_start=1
                     /product="beta-soluble NSF attachment protein"
                     /protein_id="NP_001178895.1"
                     /db_xref="GeneID:499903"
                     /db_xref="RGD:1589649"
                     /translation="MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEM
                     YTRAANMFKMAKNWSAAGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAIN
                     CLNAAIDIYTDMGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSS
                     ANKCLLKVAAYAAQLEQYQKAIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDE
                     LNAKLALEKYEEMFPAFTDSRECKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWL
                     TTMLLRIKKSIQGDGEGDGDLK"
     exon            154..233
                     /gene="Napb"
                     /gene_synonym="SNAP-beta; Snapb"
                     /inference="alignment:Splign:2.1.0"
     exon            234..350
                     /gene="Napb"
                     /gene_synonym="SNAP-beta; Snapb"
                     /inference="alignment:Splign:2.1.0"
     exon            351..397
                     /gene="Napb"
                     /gene_synonym="SNAP-beta; Snapb"
                     /inference="alignment:Splign:2.1.0"
     exon            398..475
                     /gene="Napb"
                     /gene_synonym="SNAP-beta; Snapb"
                     /inference="alignment:Splign:2.1.0"
     exon            476..531
                     /gene="Napb"
                     /gene_synonym="SNAP-beta; Snapb"
                     /inference="alignment:Splign:2.1.0"
     exon            532..616
                     /gene="Napb"
                     /gene_synonym="SNAP-beta; Snapb"
                     /inference="alignment:Splign:2.1.0"
     exon            617..721
                     /gene="Napb"
                     /gene_synonym="SNAP-beta; Snapb"
                     /inference="alignment:Splign:2.1.0"
     exon            722..790
                     /gene="Napb"
                     /gene_synonym="SNAP-beta; Snapb"
                     /inference="alignment:Splign:2.1.0"
     exon            791..841
                     /gene="Napb"
                     /gene_synonym="SNAP-beta; Snapb"
                     /inference="alignment:Splign:2.1.0"
     exon            842..4673
                     /gene="Napb"
                     /gene_synonym="SNAP-beta; Snapb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcgtcccgg gagcctcgca agtcagcaga ggaggcttta gctgcagccg gtgacatgga
       61 caacgcaggg aaagaacgag aagcggtcca gcttatggcg gaggccgaga agcgagtgaa
      121 ggcttcccac tccttcctcc gagggttgtt cggaggaaac acaagaatag aagaggcatg
      181 tgaaatgtat accagagctg caaatatgtt caagatggcc aagaactgga gtgctgcagg
      241 aaatgcattt tgtcaagccg ccaagctcca catgcagctt cagagcaagc atgactctgc
      301 tacgagcttt gtggatgctg gaaatgctta caagaaagca gaccctcaag aggctatcaa
      361 ctgcttaaat gcagccatcg acatttacac agacatggga agattcacaa tcgcagccaa
      421 gcaccatatc accattgctg agatctatga gactgagctc gtggacattg agaaggctat
      481 tgcacattat gaacaatctg ctgattatta caaaggagaa gaatctaaca gctctgctaa
      541 caagtgtctg ctgaaggtgg cagcctatgc tgcacagctg gagcagtacc agaaagccat
      601 cgagatctat gagcaggtgg gagcaaacac tatggataac cccttgctga agtacagcgc
      661 aaaggattac ttcttcaagg cagcactctg tcacttcata gtggatgagc tgaatgcaaa
      721 gcttgctctt gagaaatacg aggaaatgtt tccagcattt actgactcca gagaatgtaa
      781 attattgaaa aaacttctag aagctcatga agaacagaac agtgaagctt acactgaagc
      841 agtgaaggag tttgactcaa tatcacgttt ggatcagtgg ctgactacca tgttgcttcg
      901 tatcaagaag tccattcaag gggatggaga aggagatgga gacctcaagt gaagcgctgg
      961 catctttgtg gcatgcagct ccttcctttt tattttgtct ttgggcagag ctgtctttct
     1021 gagatgctca tttaatgact taattttgtt gtaaataagc cagccacaca gtttatgtat
     1081 tgttttagct caccacatct gtgtaatgtg agagttggag gcttctattc agtttgtggt
     1141 tatgacaacc aaagtatatc atgcttatcc gagtcctcct agttttctga gaagtactgc
     1201 caaatctttt tcttgttctt ttgatatttt cagggcccac ggttaatgtt gccacgtttt
     1261 gtgttttctt ttttcttgaa ctctggtctt caacccagtt ttatagatgc tttgcaaaga
     1321 ccctatgcac tggtatctgg atgcaacctt tatacaagtg gcttagttta gggtggttat
     1381 tagaagtagg tttgtattta atagaaaccg tttggctttc ttttatagct atcttgaagg
     1441 tgctagtgat gaatttgttt cttgttttgc tccatatgct cacatgtgca tggcaaacac
     1501 tgaaaacatc tgggatctgt tgacatcact tgcatcattc ggggaaggaa cttgctggca
     1561 ggtcctgagg tcgtttgctg tggtggagga tgtcaaggta gatttcattg tttttgtttt
     1621 tacatgcaca tgcgcacaca aaacctacaa gatggaattt tccccttctc tagacagttt
     1681 ccacttttat ttgtaatgga aatcccttca tatttgcctt aaaccatctt tagctggcat
     1741 ctcctttatt cacacattga tatactcctc cacatagtgt tctgggccac agtcatgtca
     1801 agcttgagca gagctagaca gaagattcca gctgaataca tgtagtgaag tgtccatttg
     1861 ttggacatgg tggtaaaatg ctaccagtgt ggcataagaa tctatgttat acctggttag
     1921 ataagaactt cacctatgtt tgagggtctg tggtttatct cttaactgaa ggagggattt
     1981 cattagtgtg tattagctct aatgtcctac ttgctttacc taagatgtat gctgtgtttt
     2041 ttcagatttt aacactccct gctactttat atgctgatat aactgtagac atggccttgt
     2101 ttcttgagtc tcctgtgcta tttttatgct ggggtgattt gtgcttgaag agcatgtgtt
     2161 ttagacatat tttgttatcc gttgtcctaa tgtactgcta tcatgtgaca gtgaaactcc
     2221 tgataagcag gtaaaaatgg caccagaatg gtgttttcat ctttggctgg ccctagtcta
     2281 gagttggagg atcttagagt agtacctctg cccaggccca aggctgagtg aggagtttga
     2341 ggactgatga gaaagtcaga agtaatagca agtagcaaga ggaggctgga gagatggtta
     2401 ctcttccaga gaacccacgc ttgatttcca gcacccatgt tgggtggctc aaacctacac
     2461 tccagttccc ccaggagttc cagtgcactt gccctccata tgcatgtgca tacagataaa
     2521 catacaggta aatgaaatct acacatatac gcaagcaaaa cactcatgtg taaaatgatc
     2581 tttttattat ttttaaaaag aaaagtagca gatgaagctg aaactggccc catgaggaca
     2641 ggtgttaggt gtctgtcaga ccgtcatggt ggtaataggg tgtaagtgca agaagcttcg
     2701 aggcctctgc atgtctgaaa aggggggaaa tgtgccctag aatctaatga ggattccttt
     2761 ctccttcagt gtctttaggg ggtttctgaa tgatagctga ctgtaccaaa ggtaaaattt
     2821 gcaatggaac ctaattgata cttcatggct cctttagaat ctctaaagac aaaaagtgag
     2881 ttattggggc tagagagatg cctcatttgc tcttccagag gacccagggt taaagtccca
     2941 gcactcatgt gtgggttcac acctgtctat aactcccgtc ctaagggatc caccatcttc
     3001 ttttcctcca ctggcaccag gcatgtatgt ggtacacaca catacatgca gacaaaacat
     3061 gcatacactt aagaaaaaac tatagtgtat agaaaagtga gttattgctt tattcacaac
     3121 tggccacagg cagccttgga aataaggtgt ggaaatggct ctaatcagtt cagcagaaga
     3181 gcatctaaac actgagagcc tctgtgctct gcctccctag ttcagtttcc tgatgtgact
     3241 atttaaagtg agagccatgt ggtatcttac aggacactgt tttacctttc atcaaggttg
     3301 cctaacacat ctccatgaag aagtgttggg ttgttaaagt actgtttgta ttactttgtt
     3361 gtttctttaa aagtcactta tttgctttta ctgaagttaa atgctggggc aggcatcatg
     3421 aacacttgta attctgtggt atctaggtat taagtgtagc agagaataat aaaaaaggat
     3481 ttagcttcct acacgggtgg gccatatggc accagcaagg tgttctctcg gtagacctct
     3541 aaccctttgt tctcaaaatg tttccacccg actagctaag ttcccgtgca ggttggtacc
     3601 atgccagccc cacacatcca aattccaaga cctttctctt gaactcagtt gagttgtctc
     3661 atgaaggaaa acaccacaca aacttagttt agaattaacc tgtaactcaa tcgctgggcg
     3721 ccaactacta acatcctaat tagtaagcca tactaagtta aatcctcctg agtttgaggc
     3781 cagcctgggc tacctagtta attccaggcc agcccttggt tacaatgtga gactccatct
     3841 caaaaaacaa acaaaccaac caaccacaag aagaagaaga aaaaaaaaaa aaaaaaaaaa
     3901 aaaaggaaag aaaggctgag atcagtctga gcttggatct atgttgtccc agaacttggg
     3961 aggctgaggc acgaggagca tgatttctgg actaggctaa gccacatagt agcaagacca
     4021 cctttaaaaa aaacgtgtgt gtctacacac acatatacct ggcagaagat aaaagtgagg
     4081 aaaaagtcca gacagtagta tgcacgctta ctgcctttag acatcctgca gacacagggc
     4141 agagcctaga ctttaggctt tcatggtctc tagaatatta tgagcaaagc acaatgatca
     4201 gttgttctca tacttgagtg catctggaga tagttcatag ttatggcagt caatatttct
     4261 tactgaaaag ctttcctttt gtggcaacat ttttataggt tgtgtgaatt cctttttttt
     4321 aatgacataa tacagtattt ttgcacagtt gtaaccatgt gtgatggtgt cactataacc
     4381 aaagtacatg caccagccct tgtgcattta ttgttccctc tggtattgtg cacttaaaat
     4441 gtccaaatac aaacctttgt gactgtgaag aatctggcag cacagcatgc ccgtgacctg
     4501 cctgctgcag tgtgagctgt gtggccataa gcaggccctg taaagtccta agttgctctc
     4561 aggcaagtgg gtacattata aaaacaaatc gtgtaacaat aaatctacct aagctaaaag
     4621 aacgtttgtt ttatgtgaac ctgtacagta aataaagtgg aagttatcag taa
//
