LOCUS       NM_001009409            1335 bp    mRNA    linear   ROD 20-AUG-2024
DEFINITION  Rattus norvegicus N-acetylneuraminic acid phosphatase (Nanp), mRNA.
ACCESSION   NM_001009409 XM_230779
VERSION     NM_001009409.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1335)
  AUTHORS   Maliekal,P., Vertommen,D., Delpierre,G. and Van Schaftingen,E.
  TITLE     Identification of the sequence encoding
            N-acetylneuraminate-9-phosphate phosphatase
  JOURNAL   Glycobiology 16 (2), 165-172 (2006)
   PUBMED   16237198
REFERENCE   2  (bases 1 to 1335)
  AUTHORS   Van Rinsum,J., Van Dijk,W., Hooghwinkel,G.J. and Ferwerda,W.
  TITLE     Subcellular localization and tissue distribution of sialic
            acid-forming enzymes. N-acetylneuraminate-9-phosphate synthase and
            N-acetylneuraminate 9-phosphatase
  JOURNAL   Biochem J 223 (2), 323-328 (1984)
   PUBMED   6093772
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CO399358.1, CO568277.1 and
            BC087587.1.
            
            On Jan 26, 2005 this sequence version replaced XM_230779.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087587.1, EX488625.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-21                CO399358.1         1-21
            22-598              CO568277.1         1-577
            599-1335            BC087587.1         600-1336
FEATURES             Location/Qualifiers
     source          1..1335
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..1335
                     /gene="Nanp"
                     /gene_synonym="Hdhd4; RGD1306009"
                     /note="N-acetylneuraminic acid phosphatase"
                     /db_xref="GeneID:311530"
                     /db_xref="RGD:1306009"
     exon            1..106
                     /gene="Nanp"
                     /gene_synonym="Hdhd4; RGD1306009"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..763
                     /gene="Nanp"
                     /gene_synonym="Hdhd4; RGD1306009"
                     /EC_number="3.1.3.29"
                     /note="neu5Ac-9-Pase; haloacid dehalogenase-like hydrolase
                     domain containing 4"
                     /codon_start=1
                     /product="N-acylneuraminate-9-phosphatase"
                     /protein_id="NP_001009409.1"
                     /db_xref="GeneID:311530"
                     /db_xref="RGD:1306009"
                     /translation="MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEE
                     AEVICDKVQVKLSKECFHPYSTCITDVRTSHWEEAIQETKGGADNRKLAEECYFLWKS
                     TRLQHMTLEEDVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAIVVGGEQ
                     KEEKPAPSIFYHCCDLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKSGGVPLT
                     SSPMPHYMVSSVLELPALLQSIDCKVSMSV"
     exon            107..1325
                     /gene="Nanp"
                     /gene_synonym="Hdhd4; RGD1306009"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1294..1299
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nanp"
                     /gene_synonym="Hdhd4; RGD1306009"
     polyA_site      1325
                     /gene="Nanp"
                     /gene_synonym="Hdhd4; RGD1306009"
ORIGIN      
        1 ttgggttgcg gaggctatgg ggctgagtcg ggtccgcgcg gtcttctttg acctggacaa
       61 cacactcatc gacacggccg gggcgagcag gagaggcatg ttggaggtaa taaagctctt
      121 acaatcaaaa taccactaca aagaagaggc tgaagtcatc tgcgataaag ttcaagttaa
      181 actgagcaag gagtgctttc atccctatag tacatgcatt acagatgtga ggacttcgca
      241 ctgggaagaa gcaatccagg aaaccaaagg tggtgccgac aataggaaat tggctgagga
      301 atgttatttc ctgtggaaat ctacacgctt acagcacatg accctagaag aagatgtcaa
      361 agccatgctc actgaacttc gtaaagaggt ccgcctactc ttgttaacaa acggtgacag
      421 acagacacag agggaaaaga tcgaggcttg tgcctgccag tcttactttg atgccattgt
      481 tgtaggagga gaacagaagg aagagaaacc agcaccttcc atattttatc actgctgtga
      541 tcttcttgga gtgcagccag gggactgtgt gatggttggt gacacactag aaaccgatat
      601 acaaggaggc ctgaatgcag gactgaaagc cacggtctgg ataaacaaga gtggaggagt
      661 gccactgaca tcgtccccca tgcctcacta tatggtttcc tctgtgttag aattacctgc
      721 tctcttgcaa agcatagatt gcaaagtcag catgtctgtg taaatacaga agggcacagt
      781 gaccatgttc agagccagtt tccaggatta caactaagga aagctacggt gttctgtata
      841 ttttgttcaa ttctaagaat aatgtgagtg aggaattcat agtcaaactg tgaagatcct
      901 cccaaccctg ctgctgttga taaccatagg cttgtttcat gtcagaaatc caggttttaa
      961 tcatgtagtc caaaaaactt gaagaaaggc agaatagctt atatgatgat atacaggtac
     1021 tgatttctag agtagaaata gattttttta aaaaatagat attctaaaat agagattcag
     1081 gcagctgaat cggattagta taaatactaa atcacacaaa tcaagacatt tcatagtgaa
     1141 attttacata tttaggcaaa tttttgttat aaatattgtg cctactttca atgtatatgt
     1201 tcttacctgt tatctaattt ttctgcatga ctttcggagg gctgaatttt ttgtggtgtg
     1261 atcataacag attgttatag tgtggggaaa actattaaaa ttcaaaccat ggtgcttttt
     1321 ctccaaaaaa aaaaa
//
