LOCUS       NM_001105945             738 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus nanos C2HC-type zinc finger 3 (Nanos3), mRNA.
ACCESSION   NM_001105945 XM_001072052 XM_222459
VERSION     NM_001105945.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 738)
  AUTHORS   Bhandari,D., Raisch,T., Weichenrieder,O., Jonas,S. and
            Izaurralde,E.
  TITLE     Structural basis for the Nanos-mediated recruitment of the CCR4-NOT
            complex and translational repression
  JOURNAL   Genes Dev 28 (8), 888-901 (2014)
   PUBMED   24736845
REFERENCE   2  (bases 1 to 738)
  AUTHORS   Jorgensen,A., Nielsen,J.E., Blomberg Jensen,M., Graem,N. and
            Rajpert-De Meyts,E.
  TITLE     Analysis of meiosis regulators in human gonads: a sexually
            dimorphic spatio-temporal expression pattern suggests involvement
            of DMRT1 in meiotic entry
  JOURNAL   Mol Hum Reprod 18 (11), 523-534 (2012)
   PUBMED   22899867
REFERENCE   3  (bases 1 to 738)
  AUTHORS   Julaton,V.T. and Reijo Pera,R.A.
  TITLE     NANOS3 function in human germ cell development
  JOURNAL   Hum Mol Genet 20 (11), 2238-2250 (2011)
   PUBMED   21421998
REFERENCE   4  (bases 1 to 738)
  AUTHORS   Yamaji,M., Tanaka,T., Shigeta,M., Chuma,S., Saga,Y. and Saitou,M.
  TITLE     Functional reconstruction of NANOS3 expression in the germ cell
            lineage by a novel transgenic reporter reveals distinct subcellular
            localizations of NANOS3
  JOURNAL   Reproduction 139 (2), 381-393 (2010)
   PUBMED   19861488
REFERENCE   5  (bases 1 to 738)
  AUTHORS   Suzuki,H., Tsuda,M., Kiso,M. and Saga,Y.
  TITLE     Nanos3 maintains the germ cell lineage in the mouse by suppressing
            both Bax-dependent and -independent apoptotic pathways
  JOURNAL   Dev Biol 318 (1), 133-142 (2008)
   PUBMED   18436203
REFERENCE   6  (bases 1 to 738)
  AUTHORS   Lolicato,F., Marino,R., Paronetto,M.P., Pellegrini,M., Dolci,S.,
            Geremia,R. and Grimaldi,P.
  TITLE     Potential role of Nanos3 in maintaining the undifferentiated
            spermatogonia population
  JOURNAL   Dev Biol 313 (2), 725-738 (2008)
   PUBMED   18089289
REFERENCE   7  (bases 1 to 738)
  AUTHORS   Tsuda,M., Sasaoka,Y., Kiso,M., Abe,K., Haraguchi,S., Kobayashi,S.
            and Saga,Y.
  TITLE     Conserved role of nanos proteins in germ cell development
  JOURNAL   Science 301 (5637), 1239-1241 (2003)
   PUBMED   12947200
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473972.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_001072052.1, XM_222459.3.
FEATURES             Location/Qualifiers
     source          1..738
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q11"
     gene            1..738
                     /gene="Nanos3"
                     /note="nanos C2HC-type zinc finger 3"
                     /db_xref="GeneID:288909"
                     /db_xref="RGD:1306672"
     exon            1..493
                     /gene="Nanos3"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..561
                     /gene="Nanos3"
                     /codon_start=1
                     /product="nanos homolog 3"
                     /protein_id="NP_001099415.1"
                     /db_xref="GeneID:288909"
                     /db_xref="RGD:1306672"
                     /translation="MGTFNLWTDYLGLARLVGALHEEEEPDVRLDPKPEPKPSSASQQ
                     ASKESSAAPERLCSFCKHNGESRAIYQSHVLKDEAGRVLCPILRDYVCPQCGATQEHA
                     HTRRFCPLTGQGYTSVYCYTTRNSAGKKLTRPDKAKTQNAGHRLGGEAAAGVYAGSKS
                     GRKPPGPSPSACCPSTTA"
     exon            494..738
                     /gene="Nanos3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctctgctgc tcctctggcc ggccatggga acttttaatc tttggacaga ttacctaggt
       61 ctggcaagac tggttggggc tctgcatgag gaagaggagc ctgatgtcag gctggacccc
      121 aaaccagagc ccaagccaag ctcagcaagc cagcaagcca gcaaggaatc ctcagcagct
      181 ccagaacgcc tatgttcatt ctgcaaacac aatggcgagt ctcgtgcgat ctatcagtcc
      241 catgtcctga aggatgaggc agggcgggtg ctgtgtccca tcttgcgaga ttatgtgtgt
      301 ccccagtgtg gggccactca ggagcatgcc cacactcgac gcttctgccc actcaccggc
      361 cagggctata cttctgtcta ctgctacacc acccggaatt ctgcaggcaa aaagctgacc
      421 cggcctgaca aggcaaagac acagaatgct ggccaccgcc ttggaggaga agcagcagca
      481 ggtgtctatg cgggttccaa aagtggcagg aagccccctg gaccttcacc ctcggcctgc
      541 tgtccctcca ctacggccta ggagcttgga gtggggagga ccatggtggc accgttgtca
      601 ggggtctgga cacaggcatg ctggagactg gaccttgctt aggattgagg ctggccacag
      661 tcttgtcaga ggttaccttc cccaaccctg gccctgcttg tgttgttgcc tcagtgtcta
      721 ataaatgcta agaagtgg
//
