LOCUS       NM_001393693            7164 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus sodium leak channel, non-selective (Nalcn),
            transcript variant 1, mRNA.
ACCESSION   NM_001393693
VERSION     NM_001393693.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7164)
  AUTHORS   Kang,Y., Wu,J.X. and Chen,L.
  TITLE     Structure of voltage-modulated sodium-selective NALCN-FAM155A
            channel complex
  JOURNAL   Nat Commun 11 (1), 6199 (2020)
   PUBMED   33273469
  REMARK    GeneRIF: Structure of voltage-modulated sodium-selective
            NALCN-FAM155A channel complex.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7164)
  AUTHORS   Al-Sayed,M.D., Al-Zaidan,H., Albakheet,A., Hakami,H., Kenana,R.,
            Al-Yafee,Y., Al-Dosary,M., Qari,A., Al-Sheddi,T., Al-Muheiza,M.,
            Al-Qubbaj,W., Lakmache,Y., Al-Hindi,H., Ghaziuddin,M., Colak,D. and
            Kaya,N.
  TITLE     Mutations in NALCN cause an autosomal-recessive syndrome with
            severe hypotonia, speech impairment, and cognitive delay
  JOURNAL   Am J Hum Genet 93 (4), 721-726 (2013)
   PUBMED   24075186
REFERENCE   3  (bases 1 to 7164)
  AUTHORS   Koroglu,C., Seven,M. and Tolun,A.
  TITLE     Recessive truncating NALCN mutation in infantile neuroaxonal
            dystrophy with facial dysmorphism
  JOURNAL   J Med Genet 50 (8), 515-520 (2013)
   PUBMED   23749988
REFERENCE   4  (bases 1 to 7164)
  AUTHORS   Lu,B., Su,Y., Das,S., Liu,J., Xia,J. and Ren,D.
  TITLE     The neuronal channel NALCN contributes resting sodium permeability
            and is required for normal respiratory rhythm
  JOURNAL   Cell 129 (2), 371-383 (2007)
   PUBMED   17448995
REFERENCE   5  (bases 1 to 7164)
  AUTHORS   Nash,H.A., Scott,R.L., Lear,B.C. and Allada,R.
  TITLE     An unusual cation channel mediates photic control of locomotion in
            Drosophila
  JOURNAL   Curr Biol 12 (24), 2152-2158 (2002)
   PUBMED   12498692
REFERENCE   6  (bases 1 to 7164)
  AUTHORS   Lee,J.H., Cribbs,L.L. and Perez-Reyes,E.
  TITLE     Cloning of a novel four repeat protein related to voltage-gated
            sodium and calcium channels
  JOURNAL   FEBS Lett 445 (2-3), 231-236 (1999)
   PUBMED   10094463
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.2232786.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-277               JAXUCZ010000015.1  107147582-107147858 c
            278-424             JAXUCZ010000015.1  107118749-107118895 c
            425-607             JAXUCZ010000015.1  107115383-107115565 c
            608-691             JAXUCZ010000015.1  107110119-107110202 c
            692-831             JAXUCZ010000015.1  107109009-107109148 c
            832-960             JAXUCZ010000015.1  107108783-107108911 c
            961-1115            JAXUCZ010000015.1  107092118-107092272 c
            1116-1258           JAXUCZ010000015.1  107041348-107041490 c
            1259-1363           JAXUCZ010000015.1  107041106-107041210 c
            1364-1450           JAXUCZ010000015.1  107034573-107034659 c
            1451-1582           JAXUCZ010000015.1  107014462-107014593 c
            1583-1750           JAXUCZ010000015.1  106980557-106980724 c
            1751-1942           JAXUCZ010000015.1  106978346-106978537 c
            1943-2080           JAXUCZ010000015.1  106931604-106931741 c
            2081-2155           JAXUCZ010000015.1  106916111-106916185 c
            2156-2292           JAXUCZ010000015.1  106893058-106893194 c
            2293-2434           JAXUCZ010000015.1  106891554-106891695 c
            2435-2508           JAXUCZ010000015.1  106873600-106873673 c
            2509-2610           JAXUCZ010000015.1  106858104-106858205 c
            2611-2680           JAXUCZ010000015.1  106857614-106857683 c
            2681-2772           JAXUCZ010000015.1  106855084-106855175 c
            2773-2895           JAXUCZ010000015.1  106854873-106854995 c
            2896-2952           JAXUCZ010000015.1  106851571-106851627 c
            2953-3073           JAXUCZ010000015.1  106850958-106851078 c
            3074-3205           JAXUCZ010000015.1  106850731-106850862 c
            3206-3373           JAXUCZ010000015.1  106849738-106849905 c
            3374-3478           JAXUCZ010000015.1  106848068-106848172 c
            3479-3585           JAXUCZ010000015.1  106835859-106835965 c
            3586-3706           JAXUCZ010000015.1  106830129-106830249 c
            3707-3805           JAXUCZ010000015.1  106829947-106830045 c
            3806-3899           JAXUCZ010000015.1  106827002-106827095 c
            3900-4006           JAXUCZ010000015.1  106826380-106826486 c
            4007-4081           JAXUCZ010000015.1  106826113-106826187 c
            4082-4201           JAXUCZ010000015.1  106825295-106825414 c
            4202-4270           JAXUCZ010000015.1  106823033-106823101 c
            4271-4419           JAXUCZ010000015.1  106821929-106822077 c
            4420-4513           JAXUCZ010000015.1  106820931-106821024 c
            4514-4646           JAXUCZ010000015.1  106819243-106819375 c
            4647-4762           JAXUCZ010000015.1  106818479-106818594 c
            4763-4920           JAXUCZ010000015.1  106816548-106816705 c
            4921-5071           JAXUCZ010000015.1  106814091-106814241 c
            5072-5221           JAXUCZ010000015.1  106812237-106812386 c
            5222-5339           JAXUCZ010000015.1  106809344-106809461 c
            5340-5435           JAXUCZ010000015.1  106808677-106808772 c
            5436-7164           JAXUCZ010000015.1  106805209-106806937 c
FEATURES             Location/Qualifiers
     source          1..7164
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q25"
     gene            1..7164
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /note="sodium leak channel, non-selective"
                     /db_xref="GeneID:266760"
                     /db_xref="RGD:628710"
     exon            1..277
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            278..424
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             317..5629
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     sodium leak channel non-selective protein; sodium leak
                     channel NALCN; brain voltage-gated cation channel; voltage
                     gated channel-like protein 1; four domain-type
                     voltage-gated ion channel alpha-1 subunit; voltage gated
                     channel like 1; rb21-channel"
                     /codon_start=1
                     /product="sodium leak channel NALCN isoform 1"
                     /protein_id="NP_001380622.1"
                     /db_xref="GeneID:266760"
                     /db_xref="RGD:628710"
                     /translation="MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRI
                     CAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSY
                     VKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRF
                     ELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTKPGNVT
                     WNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEA
                     SSQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQ
                     MWGTRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILS
                     MVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSL
                     HKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGS
                     LVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNA
                     VGHMWAPLVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTK
                     EKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDTCCLFRILP
                     STSSSSCDNPKRPTVEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLS
                     GSFEGQPAKERSILSVQHHIRQERRSLRHGSNSQRISRGKSLETLTQDHSNTVRYRNA
                     QREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRA
                     RFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMITVTICSCISMMFESPFRRVMH
                     APTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWM
                     PQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLV
                     FASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPR
                     VWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMI
                     GLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMY
                     DITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVPLATMSVVFTFIFVLEVTMKIIA
                     MSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVT
                     LKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKA
                     ITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAY
                     IMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLL
                     RLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEE
                     LLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELSRFLN
                     PPSIETTQPSEDTNANSQDHNTQPESSSQQQLLSPTLSDRGGSRQDAADTGKPQRKIG
                     QWRLPSAAIAEKTAPVNKMSSYSQDPEREEEEVSKGFLAPKPISHSVSSVNLRFGGRT
                     TMKSVVCKMNPMPDTASCGSEVKKWWTRQLTVESDESGDDLLDI"
     exon            425..607
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            608..691
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            692..831
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            832..960
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1115
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1116..1258
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1363
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1364..1450
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1582
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1583..1750
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1751..1942
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1943..2080
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2081..2155
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2156..2292
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2293..2434
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2435..2508
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2509..2610
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2611..2680
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2681..2772
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2773..2895
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2896..2952
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2953..3073
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            3074..3205
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            3206..3373
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            3374..3478
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            3479..3585
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            3586..3706
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            3707..3805
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            3806..3899
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            3900..4006
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            4007..4081
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            4082..4201
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            4202..4270
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            4271..4419
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            4420..4513
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            4514..4646
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            4647..4762
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            4763..4920
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            4921..5071
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            5072..5221
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            5222..5339
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            5340..5435
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            5436..7164
                     /gene="Nalcn"
                     /gene_synonym="Vgcnl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agctgcggcg ctgccttgag catcctctgt agctcgcgcc gcaaagccaa ctgcaaaagg
       61 caagcgaata aacgcaaggc caggactccc gcagctctcc ccttacccct cgcccatgag
      121 gcagacgcta gtgcagaagc agagcggagc tgactgaagc gccatacgtg aggggccgcg
      181 tccccgcccg ctcaggccgg cgcgccccgc acggatcccg cctgctgccg ctactgcagc
      241 ctcagcacca tgaccactcc gcgcgctgcg gttacagact gtggttttgt acctgcctcc
      301 cacagctaac ttcaccatgc tcaaaagaaa gcagagttcc agggtggaag cccagccagt
      361 aactgacttt ggtcctgacg aatctctgtc agacaatgct gacatactct ggattaataa
      421 gccatgggtg cactctctgc tgcgcatctg tgccatcatc agcgtcatct cagtgtgcat
      481 gaacacacct atgaccttcg agcactatcc tccccttcag tatgtgacct tcaccctgga
      541 cactttactg atgtttctct acactgcaga gatgatagca aagatgcaca tacggggaat
      601 tgtcaagggc gatagctcct atgtgaagga ccgctggtgt gtttttgatg gattcatggt
      661 cttttgcctt tgggtttctc tcgtgttaca ggtgtttgaa atagctgaca tagttgatca
      721 gatgtcacct tggggcatgc tgcggatccc acggccactc attatgatcc gggctttcag
      781 gatttatttc cgattcgaac tgccaaggac ccgaattaca aacattttaa agcggtcagg
      841 agaacaaata tggagtgtct caatcttcct cctcttcttc cttcttctgt atgggatttt
      901 aggagttcag atgtttggaa catttaccta ccactgcgta gtcaatgaca caaagccagg
      961 gaatgtaacc tggaatagct tagctatccc agatacgcac tgctcgccag agctagaaga
     1021 aggctatcag tgccccccag gatttaaatg catggacctg gaagacctgg gacttagcag
     1081 gcaagagctg ggctacagtg gctttaatga gataggcacg agtatattca cagtctatga
     1141 ggcttcatct caggaaggct gggtattcct catgtacaga gcaatcgaca gtttcccccg
     1201 ttggcgttcc tacttctact tcatcacgct gattttcttc cttgcctggc ttgtcaagaa
     1261 tgtgttcatt gctgtcatca ttgagacatt tgcagaaatc agagtacaat ttcaacaaat
     1321 gtggggaact cggagcagca caacttccac tgccaccacg cagatgttcc atgaagatgc
     1381 tgccggtggc tggcagctgg tagctgtgga tgtcaacaag ccccagggac gtgccccagc
     1441 ctgcctacag aaaatgatgc ggtcatcagt tttccacatg tttatcctga gcatggtgac
     1501 tgtggatgta atagttgctg ccagcaacta ctacaaggga gagaacttca gaaggcagta
     1561 tgacgagttc taccttgcag aggtggcttt tacagttctt tttgatctgg aagcacttct
     1621 gaagatatgg tgtttggggt ttactggcta catcagctca tctctccaca agtttgaact
     1681 acttctggtt attgggacaa ctctccatgt atacccagat ctttatcatt ctcaatttac
     1741 ctacttccag gttcttcggg tagtccggct tattaagatt tccccagcat tggaagattt
     1801 tgtgtacaag atatttggtc ccgggaaaaa acttggaagc ttggtggtgt tcactgccag
     1861 tctcctgata gttatgtccg ccatcagttt gcagatgttc tgcttcgtcg aagaactgga
     1921 cagattcacc acatttccaa gggcatttat gtccatgttc cagatcctca cccaggaagg
     1981 atgggtggat gtgatggatc agactctgaa tgctgtgggg catatgtggg ctccactggt
     2041 tgccatctat ttcatcctct accatctctt tgcaacgctg atcctcctga gtttgtttgt
     2101 tgctgttatt ttggacaact tagaacttga tgaagatcta aagaagctca aacaattaaa
     2161 acaaagtgaa gcgaacgcag ataccaaaga aaaacttcct ttgcgcttga gaatcttcga
     2221 aaaattccca aacagaccgc aaatggtgaa aatctcaaaa cttccttcag attttacagt
     2281 tcctaagatc agggaaagct tcatgaagca gttcattgac cgccagcaac aggacacctg
     2341 ctgtctcttc agaattctcc cctctacctc ttcctcatcc tgtgacaacc ccaagcggcc
     2401 cacagttgaa gacaacaaat acattgatca aaaactccgc aagtctgttt tcagcataag
     2461 ggcaaggaac cttctggaaa aggagaccgc agtcacaaaa atcttaagag cttgcactcg
     2521 acagcgcatg ctgagcggat cattcgaggg gcagccagca aaggagaggt cgatcctcag
     2581 cgtgcagcat cacatccgcc aggagcgcag gtcactcaga catggatcca acagccagag
     2641 gatcagcagg ggcaaatctc ttgaaacgtt aactcaagat cattccaata cggtgcgcta
     2701 cagaaatgca caaagagaag acagtgaaat aaagatgatc caggagaaga aggagcaagc
     2761 agagatgaaa aggaaggtgc aagaagagga gctgcgagag aaccacccat actttgacaa
     2821 gcctctcttc atcgtgggtc gagaacacag gttcagaaac ttctgccgcg tggtggttcg
     2881 agcacgcttc aatgcatcca aaacagaccc tgtcacggga gctgtgaaaa atacaaagta
     2941 ccaccaactt tatgatttgc tgggacttgt cacctacctg gactgggtca tgatcactgt
     3001 aaccatctgc tcttgcattt ctatgatgtt cgaatccccc ttccggagag tcatgcatgc
     3061 acccacttta cagatcgctg aatatgtgtt tgtgatattc atgagcattg agcttaatct
     3121 gaagattatg gcagatggct tgtttttcac tccaactgct gtcatcaggg actttggtgg
     3181 cgtcatggac atatttatct atcttgtgag cttgatattt ctttgttgga tgcctcaaaa
     3241 tgtgcctgct gagtcaggag cccagctcct gatggttctt cggtgcctaa gacctcttcg
     3301 gatattcaaa ctggtgccac aaatgaggaa agttgttcga gaacttttca gtggtttcaa
     3361 ggaaatattt ttggtctcca ttctgttgct gacactaatg cttgtttttg caagctttgg
     3421 tgttcagctc tttgccggaa agctagccaa gtgcaatgac cccaacatta tcagaaggga
     3481 agactgtaac ggcatcttca gaattaatgt aagtgtgtcc aagaacttaa atttaaaact
     3541 aagacctgga gagaaaaaac ctggattttg ggtgccccgt gtttgggcaa atcctcgtaa
     3601 ctttaacttt gacaatgtgg gaaatgctat gctggcattg tttgaagttc tgtccttgaa
     3661 aggctgggta gaagtgagag atgtcattat tcatcgtgtg gggccgatcc atggaatcta
     3721 tattcatgtt ttcgtattcc tgggttgcat gattggactg actctttttg tcggtgtagt
     3781 tattgctaac ttcaatgaaa acaaggggac agccctgctg acggtagatc agagaagatg
     3841 ggaagatctc aagagcagat tgaagatcgc acagcctctt catctcccac ctcggccgga
     3901 taatgatgga tttagagcta aaatgtatga cataacccag catccgtttt ttaaaaggac
     3961 aattgcgttg ctggttctgg cccagtctgt gttgctatct gtcaagtggg atgttgagga
     4021 tcctgtgaca gttcctttgg caaccatgtc ggtcgtgttc accttcatct ttgtcttaga
     4081 ggttacaatg aagatcatag caatgtcacc agctggtttc tggcaaagca gaagaaaccg
     4141 atatgatctc ttggtgacgt ctcttggtgt tgtgtgggtg gtgctccatt ttgctctgct
     4201 gaatgcatac acctacatga tgggagcctg tgtgattgtc tttagatttt tctccatctg
     4261 tggaaagcat gtgacattaa agatgctcct tttgactgtg gttgtcagca tgtacaagag
     4321 cttctttatc atcgtaggaa tgtttctctt gctgctgtgc tatgcctttg ctggggtggt
     4381 tctgtttggc actgtaaagt atggagagaa cattaacagg catgccaatt tttcttcagc
     4441 tggcaaagcc attactgtat tgttccgaat tgtcacaggg gaagactgga ataagattat
     4501 gcatgattgt atggttcagc ctccattttg tactcctgat gaatttacat attgggcaac
     4561 agactgtggc aattatgcag gggcacttat gtacttctgc tcattctatg tcatcatcgc
     4621 ctacatcatg ctgaatctac ttgtagccat aattgtggag aatttctctt tgttttattc
     4681 cactgaagag gaccagcttt tgagttacaa tgatcttcgc cattttcaaa tcatatggaa
     4741 tatggtagat gataaacgag agggtgtgat ccccaccttc cgagtgaagt tcctgctacg
     4801 gctactgcgt gggaggctag aagtggacct tgataaagac aagcttttgt ttaagcacat
     4861 gtgctatgag atggagaggc tgcacaatgg tggtgatgtc accttccatg atgtcttgag
     4921 catgctgtcc taccgctctg tagacatcag gaagagcctg cagctagagg aactgctggc
     4981 aagggagcag ctggagtaca ccatagagga ggaggtggct aagcagacta ttcgcatgtg
     5041 gctgaagaag tgcttaaaac gcatccgggc taaacagcag cagtcatgca gcatcatcca
     5101 cagcctgaga gagagccagc agcaagagtt gagccgattc ctgaatcctc ccagcattga
     5161 gaccacccaa ccaagcgaag ataccaacgc caacagccag gaccacaata cgcaacctga
     5221 gtcaagcagt cagcagcagc tcttgagccc tactctgtca gacagaggag gaagtcgaca
     5281 ggatgcagca gatactggga aaccccaaag aaagattggg caatggcgtc tgccctcagc
     5341 tgccatcgct gagaagacgg cacctgttaa caaaatgagc agttacagcc aagatccaga
     5401 aagagaggag gaagaggttt ccaagggctt cctggctccc aaaccaataa gccattctgt
     5461 gtcttcggtt aacctacggt ttggaggaag gacaacaatg aagtctgtgg tgtgcaagat
     5521 gaaccccatg ccagacacag cttcctgtgg ctccgaagtt aaaaagtggt ggaccagaca
     5581 gctgactgtg gagagtgacg agagtggaga tgacctccta gatatctaga ggggaagcaa
     5641 agcataggga tttatcgggt gaaaaccact gcctaatctc ttgttttatc tctgagagag
     5701 caaactgtag ttgccaaacc ctaaatttca cccgagcatg gcattttcag aattaacttt
     5761 tgttcattta ttggaatggt ccctcaaaga gtatgaagtt tcggattact ctcatgtatt
     5821 aaagaaaatc tggggcttgg gatgtaagtc agtgaaagac cacttgtcca acctatgaaa
     5881 acccgtgtgt ttaaaaccca gaaatacaag aaaagaagga aaatatgtat aatgcagtat
     5941 tgataatatt agaagctgca tcaatagtag atgtgtatta aatattcatg tattctgtct
     6001 gtgtaagata agctgtactc acctgcactc ctgtattttg ttactactcc tctcaaagag
     6061 tgctaagccc atactggccc atattgatag tacaggagtt gtagctctag ttcacctttt
     6121 tttcccattt ccaatagaaa tactttcctt gggagaaatt atttatgatt gatctgaaaa
     6181 ggtcaatcat gctaaaatga cagcagcttc aaaactacag attctggatt tttaaaaaca
     6241 ttccttttct catattattt aaaaaatatg cctgatgtta aaaaaattag acaatttgat
     6301 tttttatttc aagtactcta attgaactgt ggcctgcttc caagaaagtt atatatgtag
     6361 gtcccatgta aaggaactgg ctatagatat aattggtata taacaaacct gtaggtatat
     6421 tattcatgga cttgatgaga caaaaatatt ttgaaatctt taaaaaccct ttaaataact
     6481 gagtttataa aaaaagaata aaagtgttgg agtcaacata gctaaaagtt tacacttgag
     6541 acttattgtg gacttcatgg cttatccttg ctgtatccat tttgctatga atcagcagga
     6601 acattatggg ttggctttaa tacaccatta ctatgtagat tgaaaataat ttccctgctt
     6661 ccagaattat ctattgaaat aataacagaa gggtgccaaa acttcactct aaaccccatt
     6721 gggaatacca caacataatt atattttccc acacaccaat gctccaggtt ctctgggaaa
     6781 agtggaaata taaaattatt ggaaagcatt gatgggccct ggctgggcag ggtctcccct
     6841 gagttgtcat tatcaattgc atatttgatg atcagattat tttaagagat tgagtgtgta
     6901 aaaattccct gatgcctagg ttgctttatg atatcctttt gtctatttaa ccttcttcaa
     6961 atagccaaac attgtgtcct tcctacacag aagatgtgat ataatgtgcc catctactgc
     7021 ttttatgatt acttgtgact attagataat aggcaattca agttcatgca gccaaggggg
     7081 atttttattg ggttttatgt ttggtcagaa tttgattttt ggatataaaa gcaaaataaa
     7141 actctgattt gtaaaagaat ttac
//
