LOCUS       NM_001044252            3134 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus NAD kinase 2, mitochondrial (Nadk2), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_001044252 XM_001054488 XM_001057153 XM_345167
VERSION     NM_001044252.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3134)
  AUTHORS   Zhang,R.
  TITLE     MNADK, a Long-Awaited Human Mitochondrion-Localized NAD Kinase
  JOURNAL   J Cell Physiol 230 (8), 1697-1701 (2015)
   PUBMED   25641397
  REMARK    Review article
REFERENCE   2  (bases 1 to 3134)
  AUTHORS   Ohashi,K., Kawai,S. and Murata,K.
  TITLE     Identification and characterization of a human mitochondrial NAD
            kinase
  JOURNAL   Nat Commun 3, 1248 (2012)
   PUBMED   23212377
REFERENCE   3  (bases 1 to 3134)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001044252.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ504300.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-102               JAXUCZ010000002.1  59844854-59844955
            103-249             JAXUCZ010000002.1  59845565-59845711
            250-338             JAXUCZ010000002.1  59857374-59857462
            339-427             JAXUCZ010000002.1  59858237-59858325
            428-509             JAXUCZ010000002.1  59859542-59859623
            510-593             JAXUCZ010000002.1  59865265-59865348
            594-730             JAXUCZ010000002.1  59866348-59866484
            731-809             JAXUCZ010000002.1  59871380-59871458
            810-905             JAXUCZ010000002.1  59875563-59875658
            906-961             JAXUCZ010000002.1  59878209-59878264
            962-1015            JAXUCZ010000002.1  59878383-59878436
            1016-1139           JAXUCZ010000002.1  59883683-59883806
            1140-3134           JAXUCZ010000002.1  59884994-59886988
FEATURES             Location/Qualifiers
     source          1..3134
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q16"
     gene            1..3134
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /note="NAD kinase 2, mitochondrial"
                     /db_xref="GeneID:365699"
                     /db_xref="RGD:1306809"
     CDS             1..1278
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /EC_number="2.7.1.23"
                     /note="NAD kinase domain-containing protein 1,
                     mitochondrial; NAD kinase domain containing 1;
                     mitochondrial NAD kinase"
                     /codon_start=1
                     /product="NAD kinase 2, mitochondrial"
                     /protein_id="NP_001037717.1"
                     /db_xref="GeneID:365699"
                     /db_xref="RGD:1306809"
                     /translation="MDTSAIQQTLVKIYQRQAWQPPRKASKNETTVGKPRELAGGGSP
                     ADGGFRPSRVVVVAKTTRYEFEQQRYRYAELSEEDLKQLLALKGSSYSGLLERHHIHT
                     KNVEHIIDSLRDEGIEVRLVKRREYDEETVRWADAVIAAGGDGTMLLAASKVLDRLKP
                     VIGVNTDPERSEGHLCLPVRYTHSFPEALQKFSRGEFRWLWRQRIRLYLEGTGINPSP
                     VDLHEQQLSLNQHSRAFNIERVDDERSEASGPQLLPVRALNEVFIGESLSSRASYYEI
                     SVDDGPWEKQKSSGLNLCTGTGSKAWSFNINRVAAQAVEDVLNIARRQGNLTLPLNKE
                     LVEKVTNEYNESLLYSPEEPKILFSIREPIANRVFSSSRQRCFSSKVCVRSRCWDACM
                     VVDGGTSFEFNDGAIASMMINKEDELRTVILEQ"
     exon            1..102
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /inference="alignment:Splign:2.1.0"
     exon            103..249
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /inference="alignment:Splign:2.1.0"
     exon            250..338
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /inference="alignment:Splign:2.1.0"
     exon            339..427
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /inference="alignment:Splign:2.1.0"
     exon            428..509
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /inference="alignment:Splign:2.1.0"
     exon            510..593
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /inference="alignment:Splign:2.1.0"
     exon            594..730
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /inference="alignment:Splign:2.1.0"
     exon            731..809
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /inference="alignment:Splign:2.1.0"
     exon            810..905
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /inference="alignment:Splign:2.1.0"
     exon            906..961
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1015
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /inference="alignment:Splign:2.1.0"
     exon            1016..1139
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /inference="alignment:Splign:2.1.0"
     exon            1140..3134
                     /gene="Nadk2"
                     /gene_synonym="Nadkd1; RGD1306809"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggacacat cagctatcca gcagacactg gttaaaattt accaaagaca agcatggcaa
       61 ccacccagaa aagctagcaa aaatgaaaca actgtgggga agccgcgcga gctggcgggc
      121 ggtggtagcc ccgccgacgg cggcttccgc ccctcgcggg tggttgtggt ggcgaaaacc
      181 acccgctatg agttcgagca gcagcggtac cgctatgcgg agctctccga ggaggacctg
      241 aagcagctgc ttgcattgaa aggctcgagc tacagtgggc tacttgagcg acatcatatc
      301 cacaccaaaa atgtcgaaca catcattgat agcttacggg atgaagggat cgaggtgcgc
      361 ctggtaaagc ggagagagta cgacgaagag actgttcgat gggcagatgc tgtcatagcc
      421 gcaggaggtg atggcacgat gcttctggcc gccagtaaag ttctggacag acttaaacct
      481 gtcattgggg tcaacactga tccggaacgg tctgaaggtc acttatgtct gcctgtgcga
      541 tacacacatt ccttccccga agccttacag aagttctctc gtggtgagtt caggtggtta
      601 tggaggcagc ggatcaggtt atatctggaa gggaccggca tcaaccccag tcccgtggac
      661 ctccacgaac agcagctgag cttgaatcag cacagccgag cctttaacat cgaaagagtg
      721 gacgatgaaa gatccgaggc ttcaggacct cagcttctgc cggtgagagc gctcaatgaa
      781 gtcttcattg gggagagcct gtcatccagg gcttcttact atgaaatttc agttgatgat
      841 ggcccatggg agaagcagaa gagttcaggg ctcaatttgt gtactggaac aggatcgaag
      901 gcctggtcat tcaatatcaa cagggttgca gctcaggccg ttgaagatgt tttaaatatc
      961 gccagacgac aaggaaatct gactcttcca ctgaacaaag aattggtaga aaaagtaaca
     1021 aacgaatata acgagtcact gctctacagt ccagaagaac ccaaaatact cttcagtatc
     1081 cgagagccaa tagcaaacag agttttctca agcagccgtc agcgttgttt ctcctcaaaa
     1141 gtttgtgttc gttctcggtg ttgggatgcc tgcatggttg tggatggagg aacatctttt
     1201 gagtttaacg acggagcaat tgcttcaatg atgatcaata aagaagatga gcttcgaact
     1261 gtgattctag aacagtgaag agtttcctca gctgatagac ttgattggta gacttttctg
     1321 cagatacaga tgaccagcca gagaccgaca ttttaatggt tcttatgagg accaccacta
     1381 gagtcaaggt gacaatggga tgacgcgtgt gctgtcctgc tgattctgac aagagctgtt
     1441 cactatgaca gacagatgga ctgaatggac tagaattatg tgaatctgta ttatttacag
     1501 ttggtaacca agagcatcga tactctttag agaggcaggt taaataaagg attaagtatt
     1561 taggatttga aatttaactg tacaagtgtt gttttcttcc taactttgtg gaattggcca
     1621 catgtatcag ttgattagta cattattttt atagtaccta aaagtaaaga tttttaaaaa
     1681 ttttgatgga gaattttgat aaatcctgat gttgacttaa ctgaagttgg taaatgtgtt
     1741 ttatatagct aagacttttc taattctagg aaacagtcat gagtgactat tgattgaaaa
     1801 aagtgggatc attttaagat tatctgtaga caaattctga cttgttttgg gtaatgtcaa
     1861 caatgttaga tgaaccacat ctatgggaca aatcatgaca ctttgtaaag gtattaattt
     1921 ccatagtaat tgttgttcag acaagtaaag gagtccaaaa ggctctttcc tgtgtttgaa
     1981 tttctattac gaaaacaagg attagtagga taaccaatga ttgtattatg ttacaggagt
     2041 tcagtaaaat gttcaaaaac ccttccttta atattgggat ggattcttta ggaaacacct
     2101 aatacccagg acacagtttt ggaattgcct aagttagtat tatattcatt tactgtattc
     2161 taaaatacaa cacattctaa aatttaaaca atagctttga gggataaaac atcagcgctt
     2221 ctccatcctc tagtatgaaa acaactttta gttttggagc aagctatttt aattcttgct
     2281 tttgttttca caaaaatctt ccattgctaa ataaggggtt gtcttttcat gccatttttc
     2341 agacttgtgt attttcactt ggtgaaattg ttttttttat tgccaaaatg tttattgaag
     2401 actcattctg tgccatcata tgttatagcc atatatctat atcatgttat agatatgtca
     2461 catatgatat aatgaagtgt cgtacagaca tcggaataga ctatggaact tgagcctagt
     2521 gagatcagaa gtcaaaatct aaagccagga tgtatgatca gaccatatgt tcttagcctt
     2581 gccaaacaac acgctgctct taaaatgaaa caaatggatg tcactgtgaa gtaactgaga
     2641 tctgtctagg ttttggtgtt tattcagaac actttctttg actacattag gaaataagtg
     2701 tttttgctga gccaactcta atttctagtt tagcttttta aaaaaggata tatttaagat
     2761 accccttaat atgaaagtta aattctacac tatagaaatt cccctaaaag gcttaaaata
     2821 ccttgatagg gaaaaaaaaa atgccactct catccttact atatctagat ctggttgtcc
     2881 atgaccacca cagatgtatt tctatgcacc attaactggt aactagctgt gtggaattgt
     2941 tcataagctg cctttggaaa gatattaaaa ttacttacca tgctgggctg acagtctaac
     3001 ttctgctctg tggcaggcag ggatctattt gtaatagact catggcagag gatgttggaa
     3061 tatcaaaaat gtctttgaat gggttaacct ttcatgacca ctttatgcaa ataaaattaa
     3121 accattgtct gttc
//
